-
1
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West AB, Moore DJ, Biskup S, Bugayenko A, Smith WW, et al. (2005) Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proc Natl Acad Sci U S A 102: 16842-16847.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
-
2
-
-
70350450693
-
LRRK2 in Parkinson's disease: Function in cells and neurodegeneration
-
Webber PJ, West AB (2009) LRRK2 in Parkinson's disease: function in cells and neurodegeneration. FEBS J 276: 6436-6444.
-
(2009)
FEBS J
, vol.276
, pp. 6436-6444
-
-
Webber, P.J.1
West, A.B.2
-
3
-
-
31144443248
-
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
-
Gloeckner CJ, Kinkl N, Schumacher A, Braun RJ, O'Neill E, et al. (2006) The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity. Hum Mol Genet 15: 223-232.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 223-232
-
-
Gloeckner, C.J.1
Kinkl, N.2
Schumacher, A.3
Braun, R.J.4
O'Neill, E.5
-
4
-
-
61349137536
-
LRRK2 and neurodegeneration
-
Santpere G, Ferrer I (2009) LRRK2 and neurodegeneration. Acta Neuropathol 117: 227-246.
-
(2009)
Acta Neuropathol
, vol.117
, pp. 227-246
-
-
Santpere, G.1
Ferrer, I.2
-
5
-
-
39549117093
-
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
-
Plowey ED, Cherra SJ, 3rd, Liu YJ, Chu CT (2008) Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem 105: 1048-1056.
-
(2008)
J Neurochem
, vol.105
, pp. 1048-1056
-
-
Plowey, E.D.1
Cherra, S.J.2
Liu, Y.J.3
Chu, C.T.4
-
6
-
-
70349991886
-
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
-
Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, et al. (2009) LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model. Hum Mol Genet 18: 4022-4034.
-
(2009)
Hum Mol Genet
, vol.18
, pp. 4022-4034
-
-
Alegre-Abarrategui, J.1
Christian, H.2
Lufino, M.M.3
Mutihac, R.4
Venda, L.L.5
-
7
-
-
78650025189
-
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
-
Mortiboys H, Johansen KK, Aasly JO, Bandmann O (2010) Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2. Neurology 75: 2017-2020.
-
(2010)
Neurology
, vol.75
, pp. 2017-2020
-
-
Mortiboys, H.1
Johansen, K.K.2
Aasly, J.O.3
Bandmann, O.4
-
8
-
-
46549089664
-
LRRK2 regulates synaptic vesicle endocytosis
-
Shin N, Jeong H, Kwon J, Heo HY, Kwon JJ, et al. (2008) LRRK2 regulates synaptic vesicle endocytosis. Exp Cell Res 314: 2055-2065.
-
(2008)
Exp Cell Res
, vol.314
, pp. 2055-2065
-
-
Shin, N.1
Jeong, H.2
Kwon, J.3
Heo, H.Y.4
Kwon, J.J.5
-
9
-
-
79955544006
-
Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)
-
Chan D, Citro A, Cordy JM, Shen GC, Wolozin B (2011) Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). J Biol Chem 286: 16140-16149.
-
(2011)
J Biol Chem
, vol.286
, pp. 16140-16149
-
-
Chan, D.1
Citro, A.2
Cordy, J.M.3
Shen, G.C.4
Wolozin, B.5
-
10
-
-
78149446290
-
ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2
-
Haebig K, Gloeckner CJ, Miralles MG, Gillardon F, Schulte C, et al. (2010) ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. PLoS One 5: e13762.
-
(2010)
PLoS One
, vol.5
, pp. e13762
-
-
Haebig, K.1
Gloeckner, C.J.2
Miralles, M.G.3
Gillardon, F.4
Schulte, C.5
-
11
-
-
84863241584
-
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
-
Dodson MW, Zhang T, Jiang C, Chen S, Guo M (2012) Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning. Hum Mol Genet 21: 1350-1363.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1350-1363
-
-
Dodson, M.W.1
Zhang, T.2
Jiang, C.3
Chen, S.4
Guo, M.5
-
12
-
-
70349574622
-
Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease
-
Higashi S, Moore DJ, Yamamoto R, Minegishi M, Sato K, et al. (2009) Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease. J Neuropathol Exp Neurol 68: 994-1005.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 994-1005
-
-
Higashi, S.1
Moore, D.J.2
Yamamoto, R.3
Minegishi, M.4
Sato, K.5
-
13
-
-
34247098407
-
Leucine-rich repeat kinase 2 associates with lipid rafts
-
Hatano T, Kubo S, Imai S, Maeda M, Ishikawa K, et al. (2007) Leucine-rich repeat kinase 2 associates with lipid rafts. Hum Mol Genet 16: 678-690.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 678-690
-
-
Hatano, T.1
Kubo, S.2
Imai, S.3
Maeda, M.4
Ishikawa, K.5
-
14
-
-
33845298032
-
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
-
Biskup S, Moore DJ, Celsi F, Higashi S, West AB, et al. (2006) Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Ann Neurol 60: 557-569.
-
(2006)
Ann Neurol
, vol.60
, pp. 557-569
-
-
Biskup, S.1
Moore, D.J.2
Celsi, F.3
Higashi, S.4
West, A.B.5
-
15
-
-
84873281274
-
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk
-
MacLeod DA, Rhinn H, Kuwahara T, Zolin A, Di Paolo G, et al. (2013) RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk. Neuron 77: 425-439.
-
(2013)
Neuron
, vol.77
, pp. 425-439
-
-
MacLeod, D.A.1
Rhinn, H.2
Kuwahara, T.3
Zolin, A.4
Di Paolo, G.5
-
16
-
-
84894322830
-
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
-
Beilina A, Rudenko IN, Kaganovich A, Civiero L, Chau H, et al. (2014) Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc Natl Acad Sci U S A 111: 2626-2631.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2626-2631
-
-
Beilina, A.1
Rudenko, I.N.2
Kaganovich, A.3
Civiero, L.4
Chau, H.5
-
17
-
-
33750367865
-
Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes
-
Wasmeier C, Romao M, Plowright L, Bennett DC, Raposo G, et al. (2006) Rab38 and Rab32 control post-Golgi trafficking of melanogenic enzymes. J Cell Biol 175: 271-281.
-
(2006)
J Cell Biol
, vol.175
, pp. 271-281
-
-
Wasmeier, C.1
Romao, M.2
Plowright, L.3
Bennett, D.C.4
Raposo, G.5
-
18
-
-
67449159212
-
Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes
-
Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, et al. (2009) Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol Biol Cell 20: 2900-2908.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2900-2908
-
-
Tamura, K.1
Ohbayashi, N.2
Maruta, Y.3
Kanno, E.4
Itoh, T.5
-
19
-
-
79953217720
-
Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes
-
Tamura K, Ohbayashi N, Ishibashi K, Fukuda M (2011) Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes. J Biol Chem 286: 7507-7521.
-
(2011)
J Biol Chem
, vol.286
, pp. 7507-7521
-
-
Tamura, K.1
Ohbayashi, N.2
Ishibashi, K.3
Fukuda, M.4
-
20
-
-
70449704085
-
Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth
-
Burgo A, Sotirakis E, Simmler MC, Verraes A, Chamot C, et al. (2009) Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep 10: 1117-1124.
-
(2009)
EMBO Rep
, vol.10
, pp. 1117-1124
-
-
Burgo, A.1
Sotirakis, E.2
Simmler, M.C.3
Verraes, A.4
Chamot, C.5
-
21
-
-
85046983921
-
Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles
-
Bultema JJ, Di Pietro SM (2013) Cell type-specific Rab32 and Rab38 cooperate with the ubiquitous lysosome biogenesis machinery to synthesize specialized lysosome-related organelles. Small GTPases 4: 16-21.
-
(2013)
Small GTPases
, vol.4
, pp. 16-21
-
-
Bultema, J.J.1
Di Pietro, S.M.2
-
23
-
-
34547929585
-
Lysosome-related organelles: Driving post-Golgi compartments into specialisation
-
Raposo G, Marks MS, Cutler DF (2007) Lysosome-related organelles: driving post-Golgi compartments into specialisation. Curr Opin Cell Biol 19: 394-401.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 394-401
-
-
Raposo, G.1
Marks, M.S.2
Cutler, D.F.3
-
24
-
-
84861730626
-
BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles
-
Bultema JJ, Ambrosio AL, Burek CL, Di Pietro SM (2012) BLOC-2, AP-3, and AP-1 proteins function in concert with Rab38 and Rab32 proteins to mediate protein trafficking to lysosome-related organelles. J Biol Chem 287: 19550-19563.
-
(2012)
J Biol Chem
, vol.287
, pp. 19550-19563
-
-
Bultema, J.J.1
Ambrosio, A.L.2
Burek, C.L.3
Di Pietro, S.M.4
-
25
-
-
84868609117
-
Mechanism of platelet dense granule biogenesis: Study of cargo transport and function of Rab32 and Rab38 in a model system
-
Ambrosio AL, Boyle JA, Di Pietro SM (2012) Mechanism of platelet dense granule biogenesis: study of cargo transport and function of Rab32 and Rab38 in a model system. Blood 120: 4072-4081.
-
(2012)
Blood
, vol.120
, pp. 4072-4081
-
-
Ambrosio, A.L.1
Boyle, J.A.2
Di Pietro, S.M.3
-
26
-
-
84869491973
-
BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor
-
Gerondopoulos A, Langemeyer L, Liang JR, Linford A, Barr FA (2012) BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor. Curr Biol 22: 2135-2139.
-
(2012)
Curr Biol
, vol.22
, pp. 2135-2139
-
-
Gerondopoulos, A.1
Langemeyer, L.2
Liang, J.R.3
Linford, A.4
Barr, F.A.5
-
27
-
-
0037135975
-
Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics
-
Alto NM, Soderling J, Scott JD (2002) Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics. J Cell Biol 158: 659-668.
-
(2002)
J Cell Biol
, vol.158
, pp. 659-668
-
-
Alto, N.M.1
Soderling, J.2
Scott, J.D.3
-
28
-
-
36549032850
-
Rab32 regulates melanosome transport in Xenopus melanophores by protein kinase a recruitment
-
Park M, Serpinskaya AS, Papalopulu N, Gelfand VI (2007) Rab32 regulates melanosome transport in Xenopus melanophores by protein kinase a recruitment. Curr Biol 17: 2030-2034.
-
(2007)
Curr Biol
, vol.17
, pp. 2030-2034
-
-
Park, M.1
Serpinskaya, A.S.2
Papalopulu, N.3
Gelfand, V.I.4
-
29
-
-
68949214328
-
A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions
-
Hirota Y, Tanaka Y (2009) A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions. Cell Mol Life Sci 66: 2913-2932.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2913-2932
-
-
Hirota, Y.1
Tanaka, Y.2
-
30
-
-
79952807443
-
Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes
-
Seto S, Tsujimura K, Koide Y (2011) Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes. Traffic 12: 407-420.
-
(2011)
Traffic
, vol.12
, pp. 407-420
-
-
Seto, S.1
Tsujimura, K.2
Koide, Y.3
-
31
-
-
84869105189
-
A Rab32-dependent pathway contributes to Salmonella typhi host restriction
-
Spano S, Galan JE (2012) A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science 338: 960-963.
-
(2012)
Science
, vol.338
, pp. 960-963
-
-
Spano, S.1
Galan, J.E.2
-
32
-
-
84866765486
-
Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice
-
Liang Y, Lin S, Zou L, Zhou H, Zhang J, et al. (2012) Expression profiling of Rab GTPases reveals the involvement of Rab20 and Rab32 in acute brain inflammation in mice. Neurosci Lett 527: 110-114.
-
(2012)
Neurosci Lett
, vol.527
, pp. 110-114
-
-
Liang, Y.1
Lin, S.2
Zou, L.3
Zhou, H.4
Zhang, J.5
-
33
-
-
77951499029
-
MR urography in children. Part 2: How to use ImageJ MR urography processing software
-
Vivier PH, Dolores M, Taylor M, Dacher JN (2010) MR urography in children. Part 2: how to use ImageJ MR urography processing software. Pediatr Radiol 40: 739-746.
-
(2010)
Pediatr Radiol
, vol.40
, pp. 739-746
-
-
Vivier, P.H.1
Dolores, M.2
Taylor, M.3
Dacher, J.N.4
-
34
-
-
84873431777
-
ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2?
-
Gillardon F, Kremmer E, Froehlich T, Ueffing M, Hengerer B, et al. (2013) ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions. A method to directly monitor the active conformation of LRRK2? J Neurosci Methods 214: 62-68.
-
(2013)
J Neurosci Methods
, vol.214
, pp. 62-68
-
-
Gillardon, F.1
Kremmer, E.2
Froehlich, T.3
Ueffing, M.4
Hengerer, B.5
-
35
-
-
84878502417
-
A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6
-
Thyrock A, Ossendorf E, Stehling M, Kail M, Kurtz T, et al. (2013) A new Mint1 isoform, but not the conventional Mint1, interacts with the small GTPase Rab6. PLoS One 8: e64149.
-
(2013)
PLoS One
, vol.8
, pp. e64149
-
-
Thyrock, A.1
Ossendorf, E.2
Stehling, M.3
Kail, M.4
Kurtz, T.5
-
36
-
-
0027953535
-
Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks
-
Elazar Z, Mayer T, Rothman JE (1994) Removal of Rab GTP-binding proteins from Golgi membranes by GDP dissociation inhibitor inhibits inter-cisternal transport in the Golgi stacks. J Biol Chem 269: 794-797.
-
(1994)
J Biol Chem
, vol.269
, pp. 794-797
-
-
Elazar, Z.1
Mayer, T.2
Rothman, J.E.3
-
37
-
-
34249978483
-
Giantin interacts with both the small GTPase Rab6 and Rab1
-
Rosing M, Ossendorf E, Rak A, Barnekow A (2007) Giantin interacts with both the small GTPase Rab6 and Rab1. Exp Cell Res 313: 2318-2325.
-
(2007)
Exp Cell Res
, vol.313
, pp. 2318-2325
-
-
Rosing, M.1
Ossendorf, E.2
Rak, A.3
Barnekow, A.4
-
38
-
-
77949495744
-
Fundamental of medical image processing with personal computer system-Image processing of computed tomography with imageJ
-
Yamamoto S (2009) [Fundamental of medical image processing with personal computer system-Image processing of computed tomography with imageJ]. Nihon Hoshasen Gijutsu Gakkai Zasshi 65: 1680-1682.
-
(2009)
Nihon Hoshasen Gijutsu Gakkai Zasshi
, vol.65
, pp. 1680-1682
-
-
Yamamoto, S.1
-
39
-
-
84934441890
-
Identification and characterization of interacting partners of Rab GTPases by yeast two-hybrid analyses
-
Kail M, Barnekow A (2008) Identification and characterization of interacting partners of Rab GTPases by yeast two-hybrid analyses. Methods Mol Biol 440: 111-125.
-
(2008)
Methods Mol Biol
, vol.440
, pp. 111-125
-
-
Kail, M.1
Barnekow, A.2
-
40
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
42
-
-
0036156128
-
Molecular cloning, bacterial expression and properties of Rab31 and Rab32
-
Bao X, Faris AE, Jang EK, Haslam RJ (2002) Molecular cloning, bacterial expression and properties of Rab31 and Rab32. Eur J Biochem 269: 259-271.
-
(2002)
Eur J Biochem
, vol.269
, pp. 259-271
-
-
Bao, X.1
Faris, A.E.2
Jang, E.K.3
Haslam, R.J.4
-
43
-
-
10744223190
-
Identification and characterization of mouse Rab32 by mRNA and protein expression analysis
-
Cohen-Solal KA, Sood R, Marin Y, Crespo-Carbone SM, Sinsimer D, et al. (2003) Identification and characterization of mouse Rab32 by mRNA and protein expression analysis. Biochim Biophys Acta 1651: 68-75.
-
(2003)
Biochim Biophys Acta
, vol.1651
, pp. 68-75
-
-
Cohen-Solal, K.A.1
Sood, R.2
Marin, Y.3
Crespo-Carbone, S.M.4
Sinsimer, D.5
-
44
-
-
0024441661
-
Transformation of human kidney epithelial cells to tumorigenicity by nickel(II) and V-HA-RAS oncogene
-
Haugen A, Ryberg D, Hansteen IL, Dalen H (1989) Transformation of human kidney epithelial cells to tumorigenicity by nickel(II) and V-HA-RAS oncogene. Biol Trace Elem Res 21: 451-458.
-
(1989)
Biol Trace Elem Res
, vol.21
, pp. 451-458
-
-
Haugen, A.1
Ryberg, D.2
Hansteen, I.L.3
Dalen, H.4
-
45
-
-
40949145205
-
Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease
-
Westerlund M, Belin AC, Anvret A, Bickford P, Olson L, et al. (2008) Developmental regulation of leucine-rich repeat kinase 1 and 2 expression in the brain and other rodent and human organs: Implications for Parkinson's disease. Neuroscience 152: 429-436.
-
(2008)
Neuroscience
, vol.152
, pp. 429-436
-
-
Westerlund, M.1
Belin, A.C.2
Anvret, A.3
Bickford, P.4
Olson, L.5
-
47
-
-
78649389313
-
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
-
Cookson MR (2010) The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease. Nat Rev Neurosci 11: 791-797.
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 791-797
-
-
Cookson, M.R.1
-
48
-
-
84892588907
-
LRRK2 phosphorylates novel tau epitopes and promotes tauopathy
-
Bailey RM, Covy JP, Melrose HL, Rousseau L, Watkinson R, et al. (2013) LRRK2 phosphorylates novel tau epitopes and promotes tauopathy. Acta Neuropathol 126: 809-827.
-
(2013)
Acta Neuropathol
, vol.126
, pp. 809-827
-
-
Bailey, R.M.1
Covy, J.P.2
Melrose, H.L.3
Rousseau, L.4
Watkinson, R.5
-
49
-
-
29444437871
-
Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration
-
Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, et al. (2005) Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration. Proc Natl Acad Sci U S A 102: 18676-18681.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18676-18681
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Moore, D.J.4
Liang, Y.5
-
50
-
-
0030004228
-
Prediction and analysis of coiled-coil structures
-
Lupas A (1996) Prediction and analysis of coiled-coil structures. Methods Enzymol 266: 513-525.
-
(1996)
Methods Enzymol
, vol.266
, pp. 513-525
-
-
Lupas, A.1
-
51
-
-
0033999818
-
Rab7: A key to lysosome biogenesis
-
Bucci C, Thomsen P, Nicoziani P, McCarthy J, van Deurs B (2000) Rab7: a key to lysosome biogenesis. Mol Biol Cell 11: 467-480.
-
(2000)
Mol Biol Cell
, vol.11
, pp. 467-480
-
-
Bucci, C.1
Thomsen, P.2
Nicoziani, P.3
McCarthy, J.4
Van Deurs, B.5
-
52
-
-
0026744303
-
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
-
Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, et al. (1992) The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell 70: 715-728.
-
(1992)
Cell
, vol.70
, pp. 715-728
-
-
Bucci, C.1
Parton, R.G.2
Mather, I.H.3
Stunnenberg, H.4
Simons, K.5
-
53
-
-
76949098165
-
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
-
Wegner CS, Malerod L, Pedersen NM, Progida C, Bakke O, et al. (2010) Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5. Histochem Cell Biol 133: 41-55.
-
(2010)
Histochem Cell Biol
, vol.133
, pp. 41-55
-
-
Wegner, C.S.1
Malerod, L.2
Pedersen, N.M.3
Progida, C.4
Bakke, O.5
-
54
-
-
0028224561
-
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network
-
Riederer MA, Soldati T, Shapiro AD, Lin J, Pfeffer SR (1994) Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol 125: 573-582.
-
(1994)
J Cell Biol
, vol.125
, pp. 573-582
-
-
Riederer, M.A.1
Soldati, T.2
Shapiro, A.D.3
Lin, J.4
Pfeffer, S.R.5
-
57
-
-
0003880161
-
-
New York: Garland Science
-
Alberts B, Johnson A, Lewis J, Raff M, Roberts K, et al. (2002) Molecular Biology of the Cell. 4 ed. New York: Garland Science.
-
(2002)
Molecular Biology of the Cell. 4 Ed.
-
-
Alberts, B.1
Johnson, A.2
Lewis, J.3
Raff, M.4
Roberts, K.5
-
58
-
-
80055078598
-
Thousands of rab GTPases for the cell biologist
-
Diekmann Y, Seixas E, Gouw M, Tavares-Cadete F, Seabra MC, et al. (2011) Thousands of rab GTPases for the cell biologist. PLoS Comput Biol 7: e1002217.
-
(2011)
PLoS Comput Biol
, vol.7
, pp. e1002217
-
-
Diekmann, Y.1
Seixas, E.2
Gouw, M.3
Tavares-Cadete, F.4
Seabra, M.C.5
-
59
-
-
84866635836
-
Analysis of LRRK2 accessory repeat domains: Prediction of repeat length, number and sites of Parkinson's disease mutations
-
Mills RD, Mulhern TD, Cheng HC, Culvenor JG (2012) Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations. Biochem Soc Trans 40: 1086-1089.
-
(2012)
Biochem Soc Trans
, vol.40
, pp. 1086-1089
-
-
Mills, R.D.1
Mulhern, T.D.2
Cheng, H.C.3
Culvenor, J.G.4
-
60
-
-
84896111174
-
Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)
-
Mills RD, Mulhern TD, Liu F, Culvenor JG, Cheng HC (2014) Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2). Hum Mutat 35: 395-412.
-
(2014)
Hum Mutat
, vol.35
, pp. 395-412
-
-
Mills, R.D.1
Mulhern, T.D.2
Liu, F.3
Culvenor, J.G.4
Cheng, H.C.5
-
61
-
-
79951534656
-
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool
-
Piccoli G, Condliffe SB, Bauer M, Giesert F, Boldt K, et al. (2011) LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci 31: 2225-2237.
-
(2011)
J Neurosci
, vol.31
, pp. 2225-2237
-
-
Piccoli, G.1
Condliffe, S.B.2
Bauer, M.3
Giesert, F.4
Boldt, K.5
-
62
-
-
77957790021
-
Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties
-
Bui M, Gilady SY, Fitzsimmons RE, Benson MD, Lynes EM, et al. (2010) Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem 285: 31590-31602.
-
(2010)
J Biol Chem
, vol.285
, pp. 31590-31602
-
-
Bui, M.1
Gilady, S.Y.2
Fitzsimmons, R.E.3
Benson, M.D.4
Lynes, E.M.5
-
63
-
-
84891904255
-
Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
-
Muda K, Bertinetti D, Gesellchen F, Hermann JS, von Zweydorf F, et al. (2014) Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3. Proc Natl Acad Sci U S A 111: E34-43.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E34-E43
-
-
Muda, K.1
Bertinetti, D.2
Gesellchen, F.3
Hermann, J.S.4
Von Zweydorf, F.5
-
64
-
-
84896736721
-
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
-
Parisiadou L, Yu J, Sgobio C, Xie C, Liu G, et al. (2014) LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity. Nat Neurosci 17: 367-376.
-
(2014)
Nat Neurosci
, vol.17
, pp. 367-376
-
-
Parisiadou, L.1
Yu, J.2
Sgobio, C.3
Xie, C.4
Liu, G.5
-
65
-
-
84864150600
-
Mitochondrial dysfunction in Parkinson's disease: Molecular mechanisms and pathophysiological consequences
-
Exner N, Lutz AK, Haass C, Winklhofer KF (2012) Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J 31: 3038-3062.
-
(2012)
EMBO J
, vol.31
, pp. 3038-3062
-
-
Exner, N.1
Lutz, A.K.2
Haass, C.3
Winklhofer, K.F.4
-
66
-
-
84910004657
-
LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity
-
Gomez-Suaga P, Rivero-Rios P, Fdez E, Blanca Ramirez M, Ferrer I, et al. (2014) LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity. Hum Mol Genet.
-
(2014)
Hum Mol Genet
-
-
Gomez-Suaga, P.1
Rivero-Rios, P.2
Fdez, E.3
Blanca Ramirez, M.4
Ferrer, I.5
|