메뉴 건너뛰기




Volumn 20, Issue 37, 2014, Pages 13573-13581

Novel approach to identifying the hepatitis B virus pre-S deletions associated with hepatocellular carcinoma

Author keywords

Capillary gel electrophoresis; Hepatitis B virus; Hepatocellular carcinoma; Pre S deletion; Sequence analysis

Indexed keywords

HEPATITIS B SURFACE ANTIGEN; VIRUS DNA; PROTEIN PRECURSOR;

EID: 84909996562     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i37.13573     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 66149187115 scopus 로고    scopus 로고
    • Hepatitis B virus DNA levels and outcomes in chronic hepatitis B
    • PMID: 19399801
    • Chen CJ, Yang HI, Iloeje UH. Hepatitis B virus DNA levels and outcomes in chronic hepatitis B. Hepatology 2009; 49: S72-S84 [PMID: 19399801 DOI: 10.1002/hep.22884]
    • (2009) Hepatology , vol.49 , pp. S72-S84
    • Chen, C.J.1    Yang, H.I.2    Iloeje, U.H.3
  • 3
    • 34248345071 scopus 로고    scopus 로고
    • Immunoadhesins containing pre-S domains of hepatitis B virus large envelope protein are secreted and inhibit virus infection
    • PMID: 17329331
    • Chai N, Gudima S, Chang J, Taylor J. Immunoadhesins containing pre-S domains of hepatitis B virus large envelope protein are secreted and inhibit virus infection. J Virol 2007; 81: 4912-4918 [PMID: 17329331 DOI: 10.1128/JVI.02865-06]
    • (2007) J Virol , vol.81 , pp. 4912-4918
    • Chai, N.1    Gudima, S.2    Chang, J.3    Taylor, J.4
  • 4
    • 84862777020 scopus 로고    scopus 로고
    • Mutational complex genotype of the hepatitis B virus X?/precore regions as a novel predictive marker for hepatocellular carcinoma
    • PMID: 22136288
    • Jang JW, Chun JY, Park YM, Shin SK, Yoo W, Kim SO, Hong SP. Mutational complex genotype of the hepatitis B virus X?/precore regions as a novel predictive marker for hepatocellular carcinoma. Cancer Sci 2012; 103: 296-304 [PMID: 22136288 DOI: 10.1111/j.1349-7006.2011.02170.x]
    • (2012) Cancer Sci , vol.103 , pp. 296-304
    • Jang, J.W.1    Chun, J.Y.2    Park, Y.M.3    Shin, S.K.4    Yoo, W.5    Kim, S.O.6    Hong, S.P.7
  • 5
    • 68249152595 scopus 로고    scopus 로고
    • Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: A meta-analysis
    • PMID: 19574418
    • Liu S, Zhang H, Gu C, Yin J, He Y, Xie J, Cao G. Associations between hepatitis B virus mutations and the risk of hepatocellular carcinoma: a meta-analysis. J Natl Cancer Inst 2009; 101: 1066-1082 [PMID: 19574418 DOI: 10.1093/jnci/djp180]
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1066-1082
    • Liu, S.1    Zhang, H.2    Gu, C.3    Yin, J.4    He, Y.5    Xie, J.6    Cao, G.7
  • 6
    • 80054769187 scopus 로고    scopus 로고
    • Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients
    • PMID: 22014121
    • Tatsukawa M, Takaki A, Shiraha H, Koike K, Iwasaki Y, Kobashi H, Fujioka S, Sakaguchi K, Yamamoto K. Hepatitis B virus core promoter mutations G1613A and C1653T are significantly associated with hepatocellular carcinoma in genotype C HBV-infected patients. BMC Cancer 2011; 11: 458 [PMID: 22014121 DOI: 10.1186/1471-2407-11-458]
    • (2011) BMC Cancer , vol.11 , pp. 458
    • Tatsukawa, M.1    Takaki, A.2    Shiraha, H.3    Koike, K.4    Iwasaki, Y.5    Kobashi, H.6    Fujioka, S.7    Sakaguchi, K.8    Yamamoto, K.9
  • 7
    • 56649089786 scopus 로고    scopus 로고
    • Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: A casecontrol study
    • PMID: 18939932
    • Chen CH, Changchien CS, Lee CM, Hung CH, Hu TH, Wang JH, Wang JC, Lu SN. Combined mutations in pre-s/surface and core promoter/precore regions of hepatitis B virus increase the risk of hepatocellular carcinoma: a casecontrol study. J Infect Dis 2008; 198: 1634-1642 [PMID: 18939932 DOI: 10.1086/592990]
    • (2008) J Infect Dis , vol.198 , pp. 1634-1642
    • Chen, C.H.1    Changchien, C.S.2    Lee, C.M.3    Hung, C.H.4    Hu, T.H.5    Wang, J.H.6    Wang, J.C.7    Lu, S.N.8
  • 9
    • 35649014367 scopus 로고    scopus 로고
    • Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients
    • PMID: 17915220
    • Chen CH, Hung CH, Lee CM, Hu TH, Wang JH, Wang JC, Lu SN, Changchien CS. Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients. Gastroenterology 2007; 133: 1466-1474 [PMID: 17915220 DOI: 10.1053/j.gastro.2007.09.002]
    • (2007) Gastroenterology , vol.133 , pp. 1466-1474
    • Chen, C.H.1    Hung, C.H.2    Lee, C.M.3    Hu, T.H.4    Wang, J.H.5    Wang, J.C.6    Lu, S.N.7    Changchien, C.S.8
  • 10
    • 78650737532 scopus 로고    scopus 로고
    • Combined pre-S deletion and core promoter mutations related to hepatocellular carcinoma: A nested case-control study in China
    • PMID: 20973883
    • Qu LS, Liu TT, Jin F, Guo YM, Chen TY, Ni ZP, Shen XZ. Combined pre-S deletion and core promoter mutations related to hepatocellular carcinoma: A nested case-control study in China. Hepatol Res 2011; 41: 54-63 [PMID: 20973883 DOI: 10.1111/j.1872-034X.2010.00732.x]
    • (2011) Hepatol Res , vol.41 , pp. 54-63
    • Qu, L.S.1    Liu, T.T.2    Jin, F.3    Guo, Y.M.4    Chen, T.Y.5    Ni, Z.P.6    Shen, X.Z.7
  • 11
    • 84984539148 scopus 로고    scopus 로고
    • High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases
    • PMID: 16618410
    • Chen BF, Liu CJ, Jow GM, Chen PJ, Kao JH, Chen DS. High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. Gastroenterology 2006; 130: 1153-1168 [PMID: 16618410 DOI: 10.1053/j.gastro.2006.01.011]
    • (2006) Gastroenterology , vol.130 , pp. 1153-1168
    • Chen, B.F.1    Liu, C.J.2    Jow, G.M.3    Chen, P.J.4    Kao, J.H.5    Chen, D.S.6
  • 12
    • 84984550855 scopus 로고    scopus 로고
    • Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma
    • PMID: 17608857
    • Lin CL, Liu CH, Chen W, Huang WL, Chen PJ, Lai MY, Chen DS, Kao JH. Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma. J Gastroenterol Hepatol 2007; 22: 1098-1103 [PMID: 17608857 DOI: 10.1111/j.1440-1746.2006.04515.x]
    • (2007) J Gastroenterol Hepatol , vol.22 , pp. 1098-1103
    • Lin, C.L.1    Liu, C.H.2    Chen, W.3    Huang, W.L.4    Chen, P.J.5    Lai, M.Y.6    Chen, D.S.7    Kao, J.H.8
  • 14
    • 84875491070 scopus 로고    scopus 로고
    • Pre-S deletion and complex mutations of hepatitis B virus related to young age hepatocellular carcinoma in Qidong, China
    • PMID: 23555717
    • Qu L, Kuai X, Liu T, Chen T, Ni Z, Shen X. Pre-S deletion and complex mutations of hepatitis B virus related to young age hepatocellular carcinoma in Qidong, China. PLoS One 2013; 8: e59583 [PMID: 23555717 DOI: 10.1371/journal.pone.0059583]
    • (2013) PLoS One , vol.8 , pp. e59583
    • Qu, L.1    Kuai, X.2    Liu, T.3    Chen, T.4    Ni, Z.5    Shen, X.6
  • 15
    • 84876370404 scopus 로고    scopus 로고
    • Molecular analysis of the hepatitis B virus presurface and surface gene in patients from eastern China with occult hepatitis B
    • PMID: 23588723
    • Huang X, Qin Y, Li W, Shi Q, Xue Y, Li J, Liu C, Hollinger FB, Shen Q. Molecular analysis of the hepatitis B virus presurface and surface gene in patients from eastern China with occult hepatitis B. J Med Virol 2013; 85: 979-986 [PMID: 23588723 DOI: 10.1002/jmv.23556]
    • (2013) J Med Virol , vol.85 , pp. 979-986
    • Huang, X.1    Qin, Y.2    Li, W.3    Shi, Q.4    Xue, Y.5    Li, J.6    Liu, C.7    Hollinger, F.B.8    Shen, Q.9
  • 16
    • 84861731096 scopus 로고    scopus 로고
    • Precore mutation of hepatitis B virus may contribute to hepatocellular carcinoma risk: Evidence from an updated meta-analysis
    • PMID: 22675557
    • Liao Y, Hu X, Chen J, Cai B, Tang J, Ying B, Wang H, Wang L. Precore mutation of hepatitis B virus may contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis. PLoS One 2012; 7: e38394 [PMID: 22675557 DOI: 10.1371/journal.pone.0038394]
    • (2012) PLoS One , vol.7 , pp. e38394
    • Liao, Y.1    Hu, X.2    Chen, J.3    Cai, B.4    Tang, J.5    Ying, B.6    Wang, H.7    Wang, L.8
  • 17
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • PMID: 7612225
    • Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis. Annu Rev Immunol 1995; 13: 29-60 [PMID: 7612225 DOI: 10.1146/annurev.iy.13.040195.000333]
    • (1995) Annu Rev Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 18
    • 33745593035 scopus 로고    scopus 로고
    • Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis
    • PMID: 16863502
    • Wang HC, Huang W, Lai MD, Su IJ. Hepatitis B virus pre-S mutants, endoplasmic reticulum stress and hepatocarcinogenesis. Cancer Sci 2006; 97: 683-688 [PMID: 16863502 DOI: 10.1111/j.1349-7006.2006.00235.x]
    • (2006) Cancer Sci , vol.97 , pp. 683-688
    • Wang, H.C.1    Huang, W.2    Lai, M.D.3    Su, I.J.4
  • 19
    • 84884682491 scopus 로고    scopus 로고
    • The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress, Cell Proliferation and its Secretion
    • PMID: 24282423
    • Liu W, Cao Y, Wang T, Xiang G, Lu J, Zhang J, Hou P. The N-Glycosylation Modification of LHBs (Large Surface Proteins of HBV) Effects on Endoplasmic Reticulum Stress, Cell Proliferation and its Secretion. Hepat Mon 2013; 13: e12280 [PMID: 24282423 DOI: 10.5812/hepatmon.12280]
    • (2013) Hepat Mon , vol.13 , pp. e12280
    • Liu, W.1    Cao, Y.2    Wang, T.3    Xiang, G.4    Lu, J.5    Zhang, J.6    Hou, P.7
  • 20
    • 16244375544 scopus 로고    scopus 로고
    • Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes
    • PMID: 15726643
    • Wang HC, Chang WT, Chang WW, Wu HC, Huang W, Lei HY, Lai MD, Fausto N, Su IJ. Hepatitis B virus pre-S2 mutant upregulates cyclin A expression and induces nodular proliferation of hepatocytes. Hepatology 2005; 41: 761-770 [PMID: 15726643 DOI: 10.1002/hep.20615]
    • (2005) Hepatology , vol.41 , pp. 761-770
    • Wang, H.C.1    Chang, W.T.2    Chang, W.W.3    Wu, H.C.4    Huang, W.5    Lei, H.Y.6    Lai, M.D.7    Fausto, N.8    Su, I.J.9
  • 21
    • 84873562300 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients
    • PMID: 23172669
    • Hsieh YH, Su IJ, Yen CJ, Tsai TF, Tsai HW, Tsai HN, Huang YJ, Chen YY, Ai YL, Kao LY, Hsieh WC, Wu HC, Huang W. Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients. Carcinogenesis 2013; 34: 475-485 [PMID: 23172669 DOI: 10.1093/carcin/bgs365]
    • (2013) Carcinogenesis , vol.34 , pp. 475-485
    • Hsieh, Y.H.1    Su, I.J.2    Yen, C.J.3    Tsai, T.F.4    Tsai, H.W.5    Tsai, H.N.6    Huang, Y.J.7    Chen, Y.Y.8    Ai, Y.L.9    Kao, L.Y.10    Hsieh, W.C.11    Wu, H.C.12    Huang, W.13
  • 22
    • 35948946094 scopus 로고    scopus 로고
    • Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclin-dependent kinase inhibitor p27Kip1 through c-Jun activation domainbinding protein 1
    • PMID: 17951406
    • Hsieh YH, Su IJ, Wang HC, Tsai JH, Huang YJ, Chang WW, Lai MD, Lei HY, Huang W. Hepatitis B virus pre-S2 mutant surface antigen induces degradation of cyclin-dependent kinase inhibitor p27Kip1 through c-Jun activation domainbinding protein 1. Mol Cancer Res 2007; 5: 1063-1072 [PMID: 17951406 DOI: 10.1158/1541-7786]
    • (2007) Mol Cancer Res , vol.5 , pp. 1063-1072
    • Hsieh, Y.H.1    Su, I.J.2    Wang, H.C.3    Tsai, J.H.4    Huang, Y.J.5    Chang, W.W.6    Lai, M.D.7    Lei, H.Y.8    Huang, W.9
  • 23
    • 0037127256 scopus 로고    scopus 로고
    • The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex
    • PMID: 11704659
    • Tomoda K, Kubota Y, Arata Y, Mori S, Maeda M, Tanaka T, Yoshida M, Yoneda-Kato N, Kato JY. The cytoplasmic shuttling and subsequent degradation of p27Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J Biol Chem 2002; 277: 2302-2310 [PMID: 11704659 DOI: 10.1074/jbc.M104431200]
    • (2002) J Biol Chem , vol.277 , pp. 2302-2310
    • Tomoda, K.1    Kubota, Y.2    Arata, Y.3    Mori, S.4    Maeda, M.5    Tanaka, T.6    Yoshida, M.7    Yoneda-Kato, N.8    Kato, J.Y.9
  • 24
    • 84055216950 scopus 로고    scopus 로고
    • Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells
    • PMID: 22216150
    • Hung JH, Teng YN, Wang LH, Su IJ, Wang CC, Huang W, Lee KH, Lu KY, Wang LH. Induction of Bcl-2 expression by hepatitis B virus pre-S2 mutant large surface protein resistance to 5-fluorouracil treatment in Huh-7 cells. PLoS One 2011; 6: e28977 [PMID: 22216150 DOI: 10.1371/journal.pone.0028977]
    • (2011) PLoS One , vol.6 , pp. e28977
    • Hung, J.H.1    Teng, Y.N.2    Wang, L.H.3    Su, I.J.4    Wang, C.C.5    Huang, W.6    Lee, K.H.7    Lu, K.Y.8    Wang, L.H.9
  • 25
    • 0036905426 scopus 로고    scopus 로고
    • Full-length sequence and functional analysis of hepatitis B virus genome in a virus carrier: A case report suggesting the impact of pre-S and core promoter mutations on the progression of the disease
    • PMID: 11876799
    • Kajiya Y, Hamasaki K, Nakata K, Nakagawa Y, Miyazoe S, Takeda Y, Ohkubo K, Ichikawa T, Nakao K, Kato Y, Eguchi K. Full-length sequence and functional analysis of hepatitis B virus genome in a virus carrier: a case report suggesting the impact of pre-S and core promoter mutations on the progression of the disease. J Viral Hepat 2002; 9: 149-156 [PMID: 11876799]
    • (2002) J Viral Hepat , vol.9 , pp. 149-156
    • Kajiya, Y.1    Hamasaki, K.2    Nakata, K.3    Nakagawa, Y.4    Miyazoe, S.5    Takeda, Y.6    Ohkubo, K.7    Ichikawa, T.8    Nakao, K.9    Kato, Y.10    Eguchi, K.11
  • 26
    • 58149460672 scopus 로고    scopus 로고
    • Occult hepatitis B virus infection in hepatitis B vaccinated children in Taiwan
    • PMID: 19070923
    • Mu SC, Lin YM, Jow GM, Chen BF. Occult hepatitis B virus infection in hepatitis B vaccinated children in Taiwan. J Hepatol 2009; 50: 264-272 [PMID: 19070923 DOI: 10.1016/j.jhep.2008.09.017]
    • (2009) J Hepatol , vol.50 , pp. 264-272
    • Mu, S.C.1    Lin, Y.M.2    Jow, G.M.3    Chen, B.F.4
  • 27
    • 53849144618 scopus 로고    scopus 로고
    • High prevalence of hepatitis B virus pre-S mutation and its association with hepatocellular carcinoma in Qidong, China
    • PMID: 18726170
    • Cao Z, Bai X, Guo X, Jin Y, Qian G, Tu H. High prevalence of hepatitis B virus pre-S mutation and its association with hepatocellular carcinoma in Qidong, China. Arch Virol 2008; 153: 1807-1812 [PMID: 18726170 DOI: 10.1007/s00705-008-0176-9]
    • (2008) Arch Virol , vol.153 , pp. 1807-1812
    • Cao, Z.1    Bai, X.2    Guo, X.3    Jin, Y.4    Qian, G.5    Tu, H.6
  • 28
    • 70349687648 scopus 로고    scopus 로고
    • A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers
    • PMID: 19751529
    • Shen FC, Su IJ, Wu HC, Hsieh YH, Yao WJ, Young KC, Chang TC, Hsieh HC, Tsai HN, Huang W. A pre-S gene chip to detect pre-S deletions in hepatitis B virus large surface antigen as a predictive marker for hepatoma risk in chronic hepatitis B virus carriers. J Biomed Sci 2009; 16: 84 [PMID: 19751529 DOI: 10.1186/1423-0127-16-84]
    • (2009) J Biomed Sci , vol.16 , pp. 84
    • Shen, F.C.1    Su, I.J.2    Wu, H.C.3    Hsieh, Y.H.4    Yao, W.J.5    Young, K.C.6    Chang, T.C.7    Hsieh, H.C.8    Tsai, H.N.9    Huang, W.10
  • 29
    • 84863994760 scopus 로고    scopus 로고
    • Analysis of T-cell receptor-γ gene rearrangements using heteroduplex analysis by high-resolution microcapillary electrophoresis
    • PMID: 22738890
    • Beaufils N, Ben Lassoued A, Essaydi A, Dales JP, Formisano-Tréziny C, Bonnet N, Grob JJ, Gabert J. Analysis of T-cell receptor-γ gene rearrangements using heteroduplex analysis by high-resolution microcapillary electrophoresis. Leuk Res 2012; 36: 1119-1123 [PMID: 22738890 DOI: 10.1016/j.leukres.2012.06.003]
    • (2012) Leuk Res , vol.36 , pp. 1119-1123
    • Beaufils, N.1    Ben Lassoued, A.2    Essaydi, A.3    Dales, J.P.4    Formisano-Tréziny, C.5    Bonnet, N.6    Grob, J.J.7    Gabert, J.8
  • 30
    • 0036819603 scopus 로고    scopus 로고
    • Rapid detection of alpha + thalassaemia deletion & amp; alpha-globin gene triplication by Gap-PCR in Indian subjects
    • PMID: 12674830
    • Agarwal S, Sarwai S, Nigam N, Singhal P. Rapid detection of alpha + thalassaemia deletion & amp; alpha-globin gene triplication by Gap-PCR in Indian subjects. Indian J Med Res 2002; 116: 155-161 [PMID: 12674830]
    • (2002) Indian J Med Res , vol.116 , pp. 155-161
    • Agarwal, S.1    Sarwai, S.2    Nigam, N.3    Singhal, P.4
  • 31
    • 34447507899 scopus 로고    scopus 로고
    • Fully automated analysis of Carbohydrate-Deficient Transferrin (CDT) by using a multicapillary electrophoresis system
    • PMID: 17575578
    • Bortolotti F, De Paoli G, Pascali JP, Tagliaro F. Fully automated analysis of Carbohydrate-Deficient Transferrin (CDT) by using a multicapillary electrophoresis system. Clin Chim Acta 2007; 380: 4-7 [PMID: 17575578]
    • (2007) Clin Chim Acta , vol.380 , pp. 4-7
    • Bortolotti, F.1    De Paoli, G.2    Pascali, J.P.3    Tagliaro, F.4
  • 32
    • 84884580039 scopus 로고    scopus 로고
    • Merging a sensitive capillary electrophoresis-ultraviolet detection method with chemometric exploratory data analysis for the determination of phenolic acids and subsequent characterization of avocado fruit
    • PMID: 23993512
    • Hurtado-Fernández E, Contreras-Gutiérrez PK, Cuadros-Rodríguez L, Carrasco-Pancorbo A, Fernández-Gutiérrez A. Merging a sensitive capillary electrophoresis-ultraviolet detection method with chemometric exploratory data analysis for the determination of phenolic acids and subsequent characterization of avocado fruit. Food Chem 2013; 141: 3492-3503 [PMID: 23993512 DOI: 10.1016/j.foodchem.2013.06.007]
    • (2013) Food Chem , vol.141 , pp. 3492-3503
    • Hurtado-Fernández, E.1    Contreras-Gutiérrez, P.K.2    Cuadros-Rodríguez, L.3    Carrasco-Pancorbo, A.4    Fernández-Gutiérrez, A.5
  • 33
    • 0037180958 scopus 로고    scopus 로고
    • Detection of genetically modified maize by the polymerase chain reaction and capillary gel electrophoresis with UV detection and laserinduced fluorescence
    • PMID: 11853473
    • García-Cañas V, González R, Cifuentes A. Detection of genetically modified maize by the polymerase chain reaction and capillary gel electrophoresis with UV detection and laserinduced fluorescence. J Agric Food Chem 2002; 50: 1016-1021 [PMID: 11853473]
    • (2002) J Agric Food Chem , vol.50 , pp. 1016-1021
    • García-Cañas, V.1    González, R.2    Cifuentes, A.3
  • 34
    • 4644244923 scopus 로고    scopus 로고
    • High-throughput protein analysis by multiplexed sodium dodecyl sulfate capillary gel electrophoresis with UV absorption detection
    • PMID: 15532564
    • Luo S, Feng J, Pang HM. High-throughput protein analysis by multiplexed sodium dodecyl sulfate capillary gel electrophoresis with UV absorption detection. J Chromatogr A 2004; 1051: 131-134 [PMID: 15532564]
    • (2004) J Chromatogr A , vol.1051 , pp. 131-134
    • Luo, S.1    Feng, J.2    Pang, H.M.3
  • 35
    • 0024213708 scopus 로고
    • Rapid separation of DNA restriction fragments using capillary electrophoresis
    • PMID: 2853173
    • Cohen AS, Najarian D, Smith JA, Karger BL. Rapid separation of DNA restriction fragments using capillary electrophoresis. J Chromatogr 1988; 458: 323-333 [PMID: 2853173]
    • (1988) J Chromatogr , vol.458 , pp. 323-333
    • Cohen, A.S.1    Najarian, D.2    Smith, J.A.3    Karger, B.L.4
  • 36
    • 0030724565 scopus 로고    scopus 로고
    • Method for phosphorothioate antisense DNA sequencing by capillary electrophoresis with UV detection
    • PMID: 9336449
    • Froim D, Hopkins CE, Belenky A, Cohen AS. Method for phosphorothioate antisense DNA sequencing by capillary electrophoresis with UV detection. Nucleic Acids Res 1997; 25: 4219-4223 [PMID: 9336449]
    • (1997) Nucleic Acids Res , vol.25 , pp. 4219-4223
    • Froim, D.1    Hopkins, C.E.2    Belenky, A.3    Cohen, A.S.4
  • 37
    • 0037172695 scopus 로고    scopus 로고
    • Multiplexed capillary electrophoresis for DNA sequencing with ultra violet absorption detection
    • PMID: 12150561
    • Zhong W, Yeung ES. Multiplexed capillary electrophoresis for DNA sequencing with ultra violet absorption detection. J Chromatogr A 2002; 960: 229-239 [PMID: 12150561]
    • (2002) J Chromatogr A , vol.960 , pp. 229-239
    • Zhong, W.1    Yeung, E.S.2
  • 38
    • 80053229217 scopus 로고    scopus 로고
    • A seventeen-year prospective cohort study on association of hepatitis B virus e antigen with the risk of hepatocellular carcinoma
    • Sun Y, Chen TY, Lu PX, Wang JB, Wu Y, Zhang QN, Jin Y, Qian GS, Tu H. A seventeen-year prospective cohort study on association of hepatitis B virus e antigen with the risk of hepatocellular carcinoma. Tumor 2011; 31: 841-845
    • (2011) Tumor , vol.31 , pp. 841-845
    • Sun, Y.1    Chen, T.Y.2    Lu, P.X.3    Wang, J.B.4    Wu, Y.5    Zhang, Q.N.6    Jin, Y.7    Qian, G.S.8    Tu, H.9
  • 39
    • 38349116816 scopus 로고    scopus 로고
    • Guideline on prevention and treatment of chronic hepatitis B in China (2005)
    • Chinese Medical Association PMID: 18167196
    • Chinese Society of Hepatology, Chinese Medical Association, Chinese Society of Infectious Diseases, Chinese Medical Association. Guideline on prevention and treatment of chronic hepatitis B in China (2005). Chin Med J (Engl) 2007; 120: 2159-2173 [PMID: 18167196]
    • (2007) Chin Med J (Engl) , vol.120 , pp. 2159-2173
    • Chinese Society of Hepatology1    Chinese Society of Infectious Diseases2
  • 40
    • 56349099754 scopus 로고    scopus 로고
    • Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: A matched nested case-control study
    • PMID: 18931087
    • Fang ZL, Sabin CA, Dong BQ, Wei SC, Chen QY, Fang KX, Yang JY, Huang J, Wang XY, Harrison TJ. Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case-control study. J Gen Virol 2008; 89: 2882-2890 [PMID: 18931087 DOI: 10.1099/vir.0.2008/002824-0]
    • (2008) J Gen Virol , vol.89 , pp. 2882-2890
    • Fang, Z.L.1    Sabin, C.A.2    Dong, B.Q.3    Wei, S.C.4    Chen, Q.Y.5    Fang, K.X.6    Yang, J.Y.7    Huang, J.8    Wang, X.Y.9    Harrison, T.J.10
  • 41
    • 79952197374 scopus 로고    scopus 로고
    • Profile of pre-S deletions in the natural history of chronic hepatitis B infection
    • PMID: 20872710
    • Yeung P, Wong DK, Lai CL, Fung J, Seto WK, Yuen MF. Profile of pre-S deletions in the natural history of chronic hepatitis B infection. J Med Virol 2010; 82: 1843-1849 [PMID: 20872710 DOI: 10.1002/jmv.21901]
    • (2010) J Med Virol , vol.82 , pp. 1843-1849
    • Yeung, P.1    Wong, D.K.2    Lai, C.L.3    Fung, J.4    Seto, W.K.5    Yuen, M.F.6
  • 43
    • 70649083901 scopus 로고    scopus 로고
    • Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children
    • PMID: 19719772
    • Abe K, Thung SN, Wu HC, Tran TT, Le Hoang P, Truong KD, Inui A, Jang JJ, Su IJ. Pre-S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children. Cancer Sci 2009; 100: 2249-2254 [PMID: 19719772 DOI: 10.1111/j.1349-7006.2009.01309.x]
    • (2009) Cancer Sci , vol.100 , pp. 2249-2254
    • Abe, K.1    Thung, S.N.2    Wu, H.C.3    Tran, T.T.4    Le Hoang, P.5    Truong, K.D.6    Inui, A.7    Jang, J.J.8    Su, I.J.9
  • 44
    • 79751523518 scopus 로고    scopus 로고
    • Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B
    • PMID: 21227916
    • Yeung P, Wong DK, Lai CL, Fung J, Seto WK, Yuen MF. Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B. J Infect Dis 2011; 203: 646-654 [PMID: 21227916 DOI: 10.1093/infdis/jiq096]
    • (2011) J Infect Dis , vol.203 , pp. 646-654
    • Yeung, P.1    Wong, D.K.2    Lai, C.L.3    Fung, J.4    Seto, W.K.5    Yuen, M.F.6
  • 46
    • 78649597541 scopus 로고    scopus 로고
    • Hepatitis B virus-DNA level and basal core promoter A1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma
    • PMID: 20814897
    • Yeh CT, So M, Ng J, Yang HW, Chang ML, Lai MW, Chen TC, Lin CY, Yeh TS, Lee WC. Hepatitis B virus-DNA level and basal core promoter A1762T/G1764A mutation in liver tissue independently predict postoperative survival in hepatocellular carcinoma. Hepatology 2010; 52: 1922-1933 [PMID: 20814897 DOI: 10.1002/hep.23898]
    • (2010) Hepatology , vol.52 , pp. 1922-1933
    • Yeh, C.T.1    So, M.2    Ng, J.3    Yang, H.W.4    Chang, M.L.5    Lai, M.W.6    Chen, T.C.7    Lin, C.Y.8    Yeh, T.S.9    Lee, W.C.10
  • 47
    • 84984535405 scopus 로고    scopus 로고
    • Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma
    • PMID: 22676233
    • Kao JH, Liu CJ, Jow GM, Chen PJ, Chen DS, Chen BF. Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma. Liver Int 2012; 32: 1373-1381 [PMID: 22676233 DOI: 10.1111/j.1478-3231.2012.02826.x]
    • (2012) Liver Int , vol.32 , pp. 1373-1381
    • Kao, J.H.1    Liu, C.J.2    Jow, G.M.3    Chen, P.J.4    Chen, D.S.5    Chen, B.F.6
  • 48
    • 84855434517 scopus 로고    scopus 로고
    • The association of hepatitis B virus genotype and the basal core promoter mutation in Qidong, China
    • PMID: 20678441
    • Jin Y, Zhu Y, Chen TY, Guo X, Zhang J, Wang JB, Chen WZ, Qian GS, Tu H. [The association of hepatitis B virus genotype and the basal core promoter mutation in Qidong, China]. Zhonghua Ganzangbing Zazhi 2010; 18: 511-515 [PMID: 20678441 DOI: 10.3760/cma.j.issn.1007-3418.2010.07.010]
    • (2010) Zhonghua Ganzangbing Zazhi , vol.18 , pp. 511-515
    • Jin, Y.1    Zhu, Y.2    Chen, T.Y.3    Guo, X.4    Zhang, J.5    Wang, J.B.6    Chen, W.Z.7    Qian, G.S.8    Tu, H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.