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Volumn 20, Issue 10, 2014, Pages 1371-1380

Differential effects of fingolimod on B-cell populations in multiple sclerosis

Author keywords

B cells; CD138; CD38; Fingolimod; Memory B cell; Multiple sclerosis; Plasmablast; Proliferation; Resistance; Sphingosine 1 phosphate receptor 1

Indexed keywords

CD19 ANTIGEN; CD27 ANTIGEN; CD38 ANTIGEN; CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR3; FINGOLIMOD; HLA DR ANTIGEN; KI 67 ANTIGEN; MESSENGER RNA; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SYNDECAN 1; BIOLOGICAL MARKER; CD38 PROTEIN, HUMAN; IMMUNOSUPPRESSIVE AGENT; MEMBRANE PROTEIN; PROPANEDIOL DERIVATIVE; S1PR1 PROTEIN, HUMAN; SDC1 PROTEIN, HUMAN; SPHINGOSINE;

EID: 84909992655     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458514523496     Document Type: Article
Times cited : (54)

References (35)
  • 1
    • 11144357340 scopus 로고    scopus 로고
    • Expression of CCR7 in multiple sclerosis: Implications for CNS immunity
    • Kivisakk P, Mahad DJ, Callahan MK, et al. Expression of CCR7 in multiple sclerosis: Implications for CNS immunity. Ann Neurol 2004; 55: 627-638.
    • (2004) Ann Neurol , vol.55 , pp. 627-638
    • Kivisakk, P.1    Mahad, D.J.2    Callahan, M.K.3
  • 2
    • 84859385704 scopus 로고    scopus 로고
    • Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs
    • Cyster JG and Schwab SR. Sphingosine-1-phosphate and lymphocyte egress from lymphoid organs. Ann Rev Immunol 2012; 30: 69-94.
    • (2012) Ann Rev Immunol , vol.30 , pp. 69-94
    • Cyster, J.G.1    Schwab, S.R.2
  • 3
    • 79955455801 scopus 로고    scopus 로고
    • Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis
    • Cohen JA and Chun J. Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis. Ann Neurol 2011; 69: 759-777.
    • (2011) Ann Neurol , vol.69 , pp. 759-777
    • Cohen, J.A.1    Chun, J.2
  • 4
    • 76149093586 scopus 로고    scopus 로고
    • A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis
    • Kappos L, Radue EW, O'Connor P, et al. A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 2010; 362: 387-401.
    • (2010) N Engl J Med , vol.362 , pp. 387-401
    • Kappos, L.1    Radue, E.W.2    O'Connor, P.3
  • 5
    • 76149140914 scopus 로고    scopus 로고
    • Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
    • Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010; 362: 402-415.
    • (2010) N Engl J Med , vol.362 , pp. 402-415
    • Cohen, J.A.1    Barkhof, F.2    Comi, G.3
  • 6
    • 77955358808 scopus 로고    scopus 로고
    • Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis
    • Mehling M, Lindberg R, Raulf F, et al. Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis. Neurology 2010; 75: 403-410.
    • (2010) Neurology , vol.75 , pp. 403-410
    • Mehling, M.1    Lindberg, R.2    Raulf, F.3
  • 7
    • 84888238788 scopus 로고    scopus 로고
    • Tumefactive MS lesions under fingolimod: A case report and literature review
    • Pilz G, Harrer A, Wipfler P, et al. Tumefactive MS lesions under fingolimod: A case report and literature review. Neurology 2013; 81: 1654-1658.
    • (2013) Neurology , vol.81 , pp. 1654-1658
    • Pilz, G.1    Harrer, A.2    Wipfler, P.3
  • 8
    • 84868018268 scopus 로고    scopus 로고
    • Emerging tumefactive multiple sclerosis after switching therapy from natalizumab to fingolimod
    • Jander S, Turowski B, Kieseier BC, et al. Emerging tumefactive multiple sclerosis after switching therapy from natalizumab to fingolimod. Mult Scler 2012; 18: 1650-1652.
    • (2012) Mult Scler , vol.18 , pp. 1650-1652
    • Jander, S.1    Turowski, B.2    Kieseier, B.C.3
  • 9
    • 84871224051 scopus 로고    scopus 로고
    • Tumefactive multiple sclerosis lesions under fingolimod treatment
    • Visser F, Wattjes MP, Pouwels PJ, et al. Tumefactive multiple sclerosis lesions under fingolimod treatment. Neurology 2012; 79: 2000-2003.
    • (2012) Neurology , vol.79 , pp. 2000-2003
    • Visser, F.1    Wattjes, M.P.2    Pouwels, P.J.3
  • 10
    • 64049116465 scopus 로고    scopus 로고
    • Hemorrhaging focal encephalitis under fingolimod (FTY720) treatment: A case report
    • Leypoldt F, Munchau A, Moeller F, et al. Hemorrhaging focal encephalitis under fingolimod (FTY720) treatment: A case report. Neurology 2009; 72: 1022-1024.
    • (2009) Neurology , vol.72 , pp. 1022-1024
    • Leypoldt, F.1    Munchau, A.2    Moeller, F.3
  • 11
    • 84881295728 scopus 로고    scopus 로고
    • A case of neuromyelitis optica spectrum disorder developing a fulminant course with multiple white-matter lesions, following fingolimod treatment
    • Izaki S, Narukawa S, Kubota A, et al. [A case of neuromyelitis optica spectrum disorder developing a fulminant course with multiple white-matter lesions, following fingolimod treatment]. Rinsho Shinkeigaku 2013; 53: 513-517.
    • (2013) Rinsho Shinkeigaku , vol.53 , pp. 513-517
    • Izaki, S.1    Narukawa, S.2    Kubota, A.3
  • 12
    • 84862908479 scopus 로고    scopus 로고
    • Development of extensive brain lesions following fingolimod (FTY720) treatment in a patient with neuromyelitis optica spectrum disorder
    • Min JH, Kim BJ and Lee KH. Development of extensive brain lesions following fingolimod (FTY720) treatment in a patient with neuromyelitis optica spectrum disorder. Mult Scler 2012; 18: 113-115.
    • (2012) Mult Scler , vol.18 , pp. 113-115
    • Min, J.H.1    Kim, B.J.2    Lee, K.H.3
  • 13
    • 0032758913 scopus 로고    scopus 로고
    • B-cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions
    • Baranzini SE, Jeong MC, Butunoi C, et al. B-cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions. J Immunol 1999; 163: 5133-5144.
    • (1999) J Immunol , vol.163 , pp. 5133-5144
    • Baranzini, S.E.1    Jeong, M.C.2    Butunoi, C.3
  • 14
    • 0032167731 scopus 로고    scopus 로고
    • Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis
    • Qin Y, Duquette P, Zhang Y, et al. Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis. J Clin Invest 1998; 102: 1045-1050.
    • (1998) J Clin Invest , vol.102 , pp. 1045-1050
    • Qin, Y.1    Duquette, P.2    Zhang, Y.3
  • 15
    • 39049142995 scopus 로고    scopus 로고
    • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    • Hauser SL, Waubant E, Arnold DL, et al. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 2008; 358: 676-688.
    • (2008) N Engl J Med , vol.358 , pp. 676-688
    • Hauser, S.L.1    Waubant, E.2    Arnold, D.L.3
  • 16
    • 79954611536 scopus 로고    scopus 로고
    • Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS
    • Kowarik MC, Pellkofer HL, Cepok S, et al. Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS. Neurology 2011; 76: 1214-1221.
    • (2011) Neurology , vol.76 , pp. 1214-1221
    • Kowarik, M.C.1    Pellkofer, H.L.2    Cepok, S.3
  • 17
    • 79952501096 scopus 로고    scopus 로고
    • Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
    • Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011; 69: 292-302.
    • (2011) Ann Neurol , vol.69 , pp. 292-302
    • Polman, C.H.1    Reingold, S.C.2    Banwell, B.3
  • 18
    • 33845358504 scopus 로고    scopus 로고
    • Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica
    • Takahashi T, Fujihara K, Nakashima I, et al. Establishment of a new sensitive assay for anti-human aquaporin-4 antibody in neuromyelitis optica. Tohoku J Exp Med 2006; 210: 307-313.
    • (2006) Tohoku J Exp Med , vol.210 , pp. 307-313
    • Takahashi, T.1    Fujihara, K.2    Nakashima, I.3
  • 19
    • 79952762854 scopus 로고    scopus 로고
    • Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
    • Chihara N, Aranami T, Sato W, et al. Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc Natl Acad Sci USA 2011; 108: 3701-3706.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 3701-3706
    • Chihara, N.1    Aranami, T.2    Sato, W.3
  • 20
    • 45949087769 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses
    • Gohda M, Kunisawa J, Miura F, et al. Sphingosine 1-phosphate regulates the egress of IgA plasmablasts from Peyer's patches for intestinal IgA responses. J Immunol 2008; 180: 5335-5343.
    • (2008) J Immunol , vol.180 , pp. 5335-5343
    • Gohda, M.1    Kunisawa, J.2    Miura, F.3
  • 21
    • 33751530065 scopus 로고    scopus 로고
    • Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism
    • Kabashima K, Haynes NM, Xu Y, et al. Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism. J Exp Med 2006; 203: 2683-2690.
    • (2006) J Exp Med , vol.203 , pp. 2683-2690
    • Kabashima, K.1    Haynes, N.M.2    Xu, Y.3
  • 22
    • 3342884206 scopus 로고    scopus 로고
    • Recapitulation of B-cell differentiation in the central nervous system of patients with multiple sclerosis
    • Corcione A, Casazza S, Ferretti E, et al. Recapitulation of B-cell differentiation in the central nervous system of patients with multiple sclerosis. Proc Natl Acad Sci USA 2004; 101: 11064-11069.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11064-11069
    • Corcione, A.1    Casazza, S.2    Ferretti, E.3
  • 23
    • 77957126531 scopus 로고    scopus 로고
    • Memory B cells from a subset of treatment-naive relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFNgamma production in response to myelin basic protein and myelin oligodendrocyte glycoprotein
    • Harp CT, Ireland S, Davis LS, et al. Memory B cells from a subset of treatment-naive relapsing-remitting multiple sclerosis patients elicit CD4(+) T-cell proliferation and IFNgamma production in response to myelin basic protein and myelin oligodendrocyte glycoprotein. Eur J Immunol 2010; 40: 2942-2956.
    • (2010) Eur J Immunol , vol.40 , pp. 2942-2956
    • Harp, C.T.1    Ireland, S.2    Davis, L.S.3
  • 24
    • 84867907413 scopus 로고    scopus 로고
    • Immune activation and increased IL-21R expression are associated with the loss of memory B cells during HIV-1 infection
    • Ruffin N, Lantto R, Pensieroso S, et al. Immune activation and increased IL-21R expression are associated with the loss of memory B cells during HIV-1 infection. J Intern Med 2012; 272: 492-503.
    • (2012) J Intern Med , vol.272 , pp. 492-503
    • Ruffin, N.1    Lantto, R.2    Pensieroso, S.3
  • 25
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • Gerdes J, Lemke H, Baisch H, et al. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984; 133: 1710-1715.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3
  • 26
    • 13544251387 scopus 로고    scopus 로고
    • Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response
    • Odendahl M, Mei H, Hoyer BF, et al. Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune response. Blood 2005; 105: 1614-1621.
    • (2005) Blood , vol.105 , pp. 1614-1621
    • Odendahl, M.1    Mei, H.2    Hoyer, B.F.3
  • 27
    • 84892425327 scopus 로고    scopus 로고
    • Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica
    • Chihara N, Aranami T, Oki S, et al. Plasmablasts as migratory IgG-producing cells in the pathogenesis of neuromyelitis optica. PLoS One 2013; 8: e83036.
    • (2013) PLoS One , vol.8 , pp. e83036
    • Chihara, N.1    Aranami, T.2    Oki, S.3
  • 28
    • 10744230053 scopus 로고    scopus 로고
    • Pharmacodynamics of single doses of the novel immunosuppressant FTY720 in stable renal transplant patients
    • Budde K, L Schmouder R Nashan B, et al. Pharmacodynamics of single doses of the novel immunosuppressant FTY720 in stable renal transplant patients. Am J Transpl 2003; 3: 846-854.
    • (2003) Am J Transpl , vol.3 , pp. 846-854
    • Budde, K.1    Schmouder, R.2    Nashan, B.L.3
  • 29
    • 33646098169 scopus 로고    scopus 로고
    • FTY720 treatment of kidney transplant patients: A differential effect on B cells, naive T cells, memory T cells and NK cells
    • Vaessen LM, Van Besouw NM, Mol WM, et al. FTY720 treatment of kidney transplant patients: A differential effect on B cells, naive T cells, memory T cells and NK cells. Transpl Immunol 2006; 15: 281-288.
    • (2006) Transpl Immunol , vol.15 , pp. 281-288
    • Vaessen, L.M.1    Van Besouw, N.M.2    Mol, W.M.3
  • 30
    • 54449099880 scopus 로고    scopus 로고
    • FTY720 therapy exerts differential effects on T-cell subsets in multiple sclerosis
    • Mehling M, Brinkmann V, Antel J, et al. FTY720 therapy exerts differential effects on T-cell subsets in multiple sclerosis. Neurology 2008; 71: 1261-1267.
    • (2008) Neurology , vol.71 , pp. 1261-1267
    • Mehling, M.1    Brinkmann, V.2    Antel, J.3
  • 31
    • 78650144281 scopus 로고    scopus 로고
    • Distinct properties of circulating CD8+ T cells in FTY720-treated patients with multiple sclerosis
    • Johnson TA, Lapierre Y, Bar-Or A, et al. Distinct properties of circulating CD8+ T cells in FTY720-treated patients with multiple sclerosis. Arch Neurol 2010; 67: 1449-1455.
    • (2010) Arch Neurol , vol.67 , pp. 1449-1455
    • Johnson, T.A.1    Lapierre, Y.2    Bar-Or, A.3
  • 32
    • 79960420758 scopus 로고    scopus 로고
    • Reduction of the peripheral blood CD56(bright) NK lymphocyte subset in FTY720-treated multiple sclerosis patients
    • Johnson TA, Evans BL, Durafourt BA, et al. Reduction of the peripheral blood CD56(bright) NK lymphocyte subset in FTY720-treated multiple sclerosis patients. J Immunol 2011; 187: 570-579.
    • (2011) J Immunol , vol.187 , pp. 570-579
    • Johnson, T.A.1    Evans, B.L.2    Durafourt, B.A.3
  • 34
    • 33744802197 scopus 로고    scopus 로고
    • B-lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production and therapeutic modulation
    • Meinl E, Krumbholz M and Hohlfeld R. B-lineage cells in the inflammatory central nervous system environment: Migration, maintenance, local antibody production and therapeutic modulation. Ann Neurol 2006; 59: 880-892.
    • (2006) Ann Neurol , vol.59 , pp. 880-892
    • Meinl, E.1    Krumbholz, M.2    Hohlfeld, R.3


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