Memory B cells from a subset of treatment-naïve relapsing-remitting multiple sclerosis patients elicit CD4+ T-cell proliferation and IFN-γ production in response to myelin basic protein and myelin oligodendrocyte glycoprotein

European Journal of Immunology

Volumn 40, Issue 10, 2010, Pages 2942-2956

  Harp, Christopher T ^a   Ireland, Sara ^a   Davis, Laurie S ^a   Remington, Gina ^a   Cassidy, Bonnie ^a   Cravens, Petra D ^a   Stuve, Olaf ^a,b   Lovett Racke, Amy E ^c   Eagar, Todd N ^a   Greenberg, Benjamin M ^a   Racke, Michael K ^c   Cowell, Lindsay G ^d   Karandikar, Nitin J ^a,e   Frohman, Elliot M ^a   Monson, Nancy L ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA North Texas Health Care System   (United States)

^c THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Ag presentation; Autoimmunity; B cells; MS

Indexed keywords

GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; LYMPHOTOXIN ALPHA BETA; MYELIN BASIC PROTEIN; MYELIN OLIGODENDROCYTE GLYCOPROTEIN;

ADULT; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN CELL; INTERFERON PRODUCTION; LYMPHOCYTE PROLIFERATION; MALE; MEMORY CELL; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RECURRENT DISEASE;

ADULT; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOLOGIC MEMORY; IMMUNOPHENOTYPING; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; LYMPHOTOXIN-ALPHA; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; MYELIN BASIC PROTEINS; MYELIN-ASSOCIATED GLYCOPROTEIN; YOUNG ADULT;

EID: 77957126531     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201040516     Document Type: Article

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