The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina

Journal of Neuroscience

Volumn 34, Issue 46, 2014, Pages 15356-15368

  Masuda, Xtomohiro ^a   Zhang, Xiaodong ^b   Berlinicke, Cindy ^a   Wan, Jun ^a   Yerrabelli, Anitha ^a   Conner, Elizabeth A ^d   Kjellstrom, Sten ^d   Bush, Ronald ^d   Thorgeirsson, Snorri S ^d   Swaroop, Anand ^d   Chen, Shiming ^b,c   Zack, Donald J ^a,e,f,g,h  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Departments of Ophthalmology and Visual Sciences   (France)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e Departments of Molecular Biology and Genetics   (France)

^f Neuroscience   (France)

^g JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h INSTITUT DE LA VISION   (France)

Author keywords

Gene expression; Opsin; Photoreceptor; Retina; Transcription factor

Indexed keywords

CELL NUCLEUS RECEPTOR; CONE OPSIN; CYCLOPHILIN A; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 5; GENERAL TRANSCRIPTION FACTOR 2 I REPEAT DOMAIN CONTAINING PROTEIN 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HISTONE DEACETYLASE 2; HOMEOBOX PROTEIN CHX10; HOMEOBOX PROTEIN CUX2; M OPSIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PHOSDUCIN; PROTEIN; RELAXIN INSULIN LIKE FAMILY PEPTIDE RECEPTOR 1; RETINA S ANTIGEN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RETINOID RELATED ORPHAN RECEPTOR BETA; RHODOPSIN; S OPSIN; SMALL INTERFERING RNA; STAT3 PROTEIN; THYROID HORMONE RECEPTOR BETA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CRX; TRANSCRIPTION FACTOR NEURAL RETINA LEUCINE ZIPPER; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; UNINDEXED DRUG; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CONE ROD HOMEOBOX PROTEIN; EYE PROTEIN; GTF2IRD1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; MUSCLE PROTEIN; NRL PROTEIN, MOUSE; NUCLEAR PROTEIN; OPSIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL FATE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CRYOPROTECTION; ELECTROPHYSIOLOGY; ELECTRORETINOGRAPHY; GENE EXPRESSION; GENE INACTIVATION; GENE MUTATION; GENETIC SCREENING; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; IN VITRO STUDY; IN VIVO STUDY; LASER CAPTURE MICRODISSECTION; LASER MICROSCOPY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PHOTORECEPTOR; POLYMERASE CHAIN REACTION; PRIMARY CELL CULTURE; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; REGULATOR GENE; RETINA; RETINA CONE; RETINA ROD; RNA EXTRACTION; TRANSIENT TRANSFECTION; VISUAL SYSTEM FUNCTION; WESTERN BLOTTING; ANIMAL; GENE EXPRESSION REGULATION; KNOCKOUT MOUSE; METABOLISM; PHYSIOLOGY;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; ELECTRORETINOGRAPHY; EYE PROTEINS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; MICE; MICE, KNOCKOUT; MUSCLE PROTEINS; NUCLEAR PROTEINS; OPSINS; PRIMARY CELL CULTURE; RETINA; RETINAL CONE PHOTORECEPTOR CELLS; RETINAL ROD PHOTORECEPTOR CELLS; RHODOPSIN; THYROID HORMONE RECEPTORS BETA; TRANS-ACTIVATORS;

EID: 84909972090     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2089-14.2014     Document Type: Article

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