The contribution of cell surface FcRn in monoclonal antibody serum uptake from the intestine in suckling rat pups

Frontiers in Pharmacology

Volumn 5, Issue OCT, 2014, Pages

  Cooper, Philip R ^a   Kliwinski, Connie M ^b   Perkinson, Robert A ^a   Ragwan, Edwin ^a   Mabus, John R ^a   Powers, Gordon D ^a   Dorai, Haimanti ^a   Giles Komar, Jill ^a   Hornby, Pamela J ^a  

^a Johnson Johnson Pharmaceutical R D   (United States)

^b Biologics Research   (United States)

Author keywords

Bioavailability; Cell surface receptor; FcRn; IgG; Uptake

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IMMUNOASSAY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOHISTOCHEMISTRY; INTESTINE ABSORPTION; MALE; NONHUMAN; PH; PINOCYTOSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; RAT; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SURFACE PLASMON RESONANCE; TISSUE DISTRIBUTION;

EID: 84909967019     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2014.00225     Document Type: Article

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