Contribution of FcRn binding to intestinal uptake of IgG in suckling rat pups and human FcRn-transgenic mice

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 304, Issue 3, 2013, Pages

  Kliwinski, C ^a   Cooper, P R ^b   Perkinson, R ^b   Mabus, J R ^b   Tam, S H ^b   Wilkinson, T M ^b   Giles Komar, J ^b   Scallon, B ^b   Powers, G D ^b   Hornby, P J ^b  

^a Biologics Toxicology   (United States)

^b Biotechnology Center of Excellence   (United States)

Author keywords

Antibody; FcRn; Gastrointestinal; IgG; Neonatal receptor; Transcytosis

Indexed keywords

FC RECEPTOR; FCRN PROTEIN; IMMUNOGLOBULIN G; ISOFLURANE; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD SAMPLING; CIRCULATION; CONTROLLED STUDY; FEMALE; IMMUNOASSAY; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INTESTINE ABSORPTION; INTESTINE CELL; INTESTINE EPITHELIUM CELL; INTESTINE LYMPH; INTESTINE VILLUS; MALE; MOUSE; NEWBORN; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; RAT; SUCKLING; TRANSCYTOSIS; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; ANIMALS, SUCKLING; ANTIBODIES, MONOCLONAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTEROCYTES; EPITHELIAL CELLS; FEMALE; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOASSAY; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; INTESTINES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; RATS; RECEPTORS, FC; TRANSCYTOSIS;

EID: 84873362213     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00340.2012     Document Type: Article

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