Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis

Pharmaceutical Research

Volumn 31, Issue 4, 2014, Pages 908-922

  Hornby, Pamela J ^a,e   Cooper, Philip R ^a   Kliwinski, Connie ^b   Ragwan, Edwin ^a   Mabus, John R ^a   Harman, Benjamin ^a   Thompson, Suzanne ^c   Kauffman, Amanda L ^a   Yan, Zhengyin ^d   Tam, Susan H ^a   Dorai, Haimanti ^a   Powers, Gordon D ^a   Giles Komar, Jill ^a  

^a Biologics Research   (United States)

^b Biologics Toxicology   (United States)

^c ETHICON INC   (United States)

^d Discovery Sciences Janssen Pharmaceutical J and J   (United States)

^e JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

drug delivery; epithelial cell; Fc receptor; monoclonal antibody; oral bioavailability

Indexed keywords

FC RECEPTOR; GROWTH FACTOR M13; GROWTH FACTOR M15; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY H435A; MONOCLONAL ANTIBODY N434A; RSV B21M ANTIBODY; UNCLASSIFIED DRUG; FC RECEPTOR, NEONATAL; HLA ANTIGEN CLASS 1; IMMUNOGLOBULIN G; MESSENGER RNA;

ANIMAL EXPERIMENT; ARTICLE; ASCENDING COLON; BINDING AFFINITY; CELL SURFACE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG UPTAKE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HAPLORHINI; HUMAN; HUMAN CELL; ILEUM; IMMUNOHISTOCHEMISTRY; INTESTINE CELL; INTESTINE MUCOSA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCYTOSIS; ADULT; ANIMAL; BIOSYNTHESIS; CACO 2 CELL LINE; GENE EXPRESSION REGULATION; MACACA FASCICULARIS; METABOLISM; MIDDLE AGED; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; YOUNG ADULT;

ADULT; ANIMALS; CACO-2 CELLS; FEMALE; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNOGLOBULIN G; INTESTINAL MUCOSA; MACACA FASCICULARIS; MALE; MIDDLE AGED; ORGAN CULTURE TECHNIQUES; RATS; RECEPTORS, FC; RNA, MESSENGER; TRANSCYTOSIS; YOUNG ADULT;

EID: 84897015338     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1212-3     Document Type: Article

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