Gln-362 of angiopoietin-2 mediates migration of tumor and endothelial cells through association with α5β1 integrin

Journal of Biological Chemistry

Volumn 289, Issue 45, 2014, Pages 31330-31340

  Lee, Hyo Seon ^a   Oh, Seung Ja ^a   Lee, Kwang Hoon ^a,c   Lee, Yoon Sook ^a   Ko, Eun ^a   Kim, Kyung Eun ^a   Kim, Hyung Chan ^a   Kim, Seokkyun ^a   Song, Paul H ^a   Kim, Yong In ^a   Kim, Chungho ^a,b   Han, Sangyeul ^a  

^a SAMSUNG Electronics   (South Korea)

^b Korea University   (South Korea)

^c New Drug Development Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; TUMORS;

ANGIOGENESIS; ANGIOPOIETIN-2; FOCAL ADHESION KINASE; INTEGRIN REGULATION; MOLECULAR MECHANISM; NON-ENDOTHELIAL CELLS; TUMOR INVASION; WILD TYPES;

ENDOTHELIAL CELLS;

ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; FOCAL ADHESION KINASE; GLUTAMINE; VERY LATE ACTIVATION ANTIGEN 5; INTEGRIN;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ANGIOGENESIS; ARTICLE; BINDING KINETICS; BINDING SITE; CANCER CELL; CANCER CELL LINE; CELL ADHESION; CELL MIGRATION; CELL MIGRATION ASSAY; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CORRELATIONAL STUDY; GLIOMA CELL; HUMAN; HUMAN CELL; METASTASIS; MUTATIONAL ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RESIDUE ANALYSIS; SIGNAL TRANSDUCTION; TUMOR INVASION; UMBILICAL VEIN ENDOTHELIAL CELL; WILD TYPE; ANIMAL; CELL MOTION; CHO CELL LINE; CRICETULUS; CYTOLOGY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HAMSTER; METABOLISM; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PLASMID; PROTEIN TERTIARY STRUCTURE; TUMOR CELL LINE;

ANGIOPOIETIN-2; ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHO CELLS; CRICETINAE; CRICETULUS; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLUTAMINE; HUMANS; INTEGRIN ALPHA5BETA1; INTEGRINS; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, TIE-2;

EID: 84909619196     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.572594     Document Type: Article

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