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Volumn 20, Issue 33, 2014, Pages 11727-11735

MicroRNAs as novel predictive biomarkers and therapeutic targets in colorectal cancer

Author keywords

5 fluorouracil; Colorectal cancer; Epidermal growth factor receptor; microRNAs; Targeted therapy

Indexed keywords

ANGIOGENESIS INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; FLUOROURACIL; MICRORNA; MICRORNA 126; MICRORNA 129; MICRORNA 143; MICRORNA 148A; MICRORNA 192; MICRORNA 19B; MICRORNA 200C; MICRORNA 203; MICRORNA 21; MICRORNA 215; MICRORNA 31; MICRORNA 34A; MICRORNA LET 7; TUMOR MARKER; UNCLASSIFIED DRUG; VASCULOTROPIN; ANTINEOPLASTIC AGENT;

EID: 84909608169     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i33.11727     Document Type: Review
Times cited : (74)

References (73)
  • 2
    • 84890586884 scopus 로고    scopus 로고
    • Selected gastrointestinal cancer presentations from the American Society of Clinical Oncology annual meeting 2013 in review: It is not about the destination, it is about the journey
    • PMID: 24283747
    • Scartozzi M, Giampieri R, Del Prete M, Faloppi L, Bianconi M, Vincenzi B, Tonini G, Santini D, Cascinu S. Selected gastrointestinal cancer presentations from the American Society of Clinical Oncology annual meeting 2013 in review: it is not about the destination, it is about the journey. Expert Opin Pharmacother 2014; 15: 143-150 [PMID: 24283747 DOI: 10.1517/14656566.2014.860964]
    • (2014) Expert Opin Pharmacother , vol.15 , pp. 143-150
    • Scartozzi, M.1    Giampieri, R.2    Del Prete, M.3    Faloppi, L.4    Bianconi, M.5    Vincenzi, B.6    Tonini, G.7    Santini, D.8    Cascinu, S.9
  • 3
    • 58649089340 scopus 로고    scopus 로고
    • Role of cancer microenvironment in metastasis: Focus on colon cancer
    • PMID: 19308686
    • Gout S, Huot J. Role of cancer microenvironment in metastasis: focus on colon cancer. Cancer Microenviron 2008; 1: 69-83 [PMID: 19308686 DOI: 10.1007/s12307-008-0007-2]
    • (2008) Cancer Microenviron , vol.1 , pp. 69-83
    • Gout, S.1    Huot, J.2
  • 6
    • 62449205665 scopus 로고    scopus 로고
    • Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition
    • PMID: 19244128
    • Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren G, Samuel S, Kim MP, Lim SJ, Ellis LM. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res 2009; 69: 1951-1957 [PMID: 19244128 DOI: 10.1158/0008-5472.CAN-08-2023]
    • (2009) Cancer Res , vol.69 , pp. 1951-1957
    • Dallas, N.A.1    Xia, L.2    Fan, F.3    Gray, M.J.4    Gaur, P.5    Van Buren, G.6    Samuel, S.7    Kim, M.P.8    Lim, S.J.9    Ellis, L.M.10
  • 7
    • 84878862969 scopus 로고    scopus 로고
    • Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: Evidence in human tumor-derived cell lines and mouse xenografts
    • PMID: 23762272
    • de la Cueva A, Ramírez de Molina A, Alvarez-Ayerza N, Ramos MA, Cebrián A, Del Pulgar TG, Lacal JC. Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PLoS One 2013; 8: e64961 [PMID: 23762272 DOI: 10.1371/journal.pone.0064961]
    • (2013) PLoS One , vol.8 , pp. e64961
    • De La Cueva, A.1    Ramírez De Molina, A.2    Alvarez-Ayerza, N.3    Ramos, M.A.4    Cebrián, A.5    Del Pulgar, T.G.6    Lacal, J.C.7
  • 10
    • 53449098390 scopus 로고    scopus 로고
    • Predictive value of thymidylate synthase expression in advanced colorectal cancer patients receiving fluoropyrimidine-based chemotherapy: Evidence from 24 studies
    • PMID: 18729195
    • Qiu LX, Tang QY, Bai JL, Qian XP, Li RT, Liu BR, Zheng MH. Predictive value of thymidylate synthase expression in advanced colorectal cancer patients receiving fluoropyrimidine-based chemotherapy: evidence from 24 studies. Int J Cancer 2008; 123: 2384-2389 [PMID: 18729195 DOI: 10.1002/ijc.23822]
    • (2008) Int J Cancer , vol.123 , pp. 2384-2389
    • Qiu, L.X.1    Tang, Q.Y.2    Bai, J.L.3    Qian, X.P.4    Li, R.T.5    Liu, B.R.6    Zheng, M.H.7
  • 11
    • 84877641194 scopus 로고    scopus 로고
    • Research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma
    • PMID: 23691439
    • Ye DJ, Zhang JM. Research development of the relationship between thymidine phosphorylase expression and colorectal carcinoma. Cancer Biol Med 2013; 10: 10-15 [PMID: 23691439 DOI: 10.7497/j.issn.2095-3941.2013.01.002]
    • (2013) Cancer Biol Med , vol.10 , pp. 10-15
    • Ye, D.J.1    Zhang, J.M.2
  • 12
    • 67651154618 scopus 로고    scopus 로고
    • Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy
    • PMID: 19386128
    • Chang DZ, Kumar V, Ma Y, Li K, Kopetz S. Individualized therapies in colorectal cancer: KRAS as a marker for response to EGFR-targeted therapy. J Hematol Oncol 2009; 2: 18 [PMID: 19386128 DOI: 10.1186/1756-8722-2-18]
    • (2009) J Hematol Oncol , vol.2 , pp. 18
    • Chang, D.Z.1    Kumar, V.2    Ma, Y.3    Li, K.4    Kopetz, S.5
  • 13
    • 84869178810 scopus 로고    scopus 로고
    • Functional dissection of the epidermal growth factor receptor epitopes targeted by panitumumab and cetuximab
    • PMID: 23226096
    • Voigt M, Braig F, Göthel M, Schulte A, Lamszus K, Bokemeyer C, Binder M. Functional dissection of the epidermal growth factor receptor epitopes targeted by panitumumab and cetuximab. Neoplasia 2012; 14: 1023-1031 [PMID: 23226096]
    • (2012) Neoplasia , vol.14 , pp. 1023-1031
    • Voigt, M.1    Braig, F.2    Göthel, M.3    Schulte, A.4    Lamszus, K.5    Bokemeyer, C.6    Binder, M.7
  • 15
    • 84874167463 scopus 로고    scopus 로고
    • EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: A systematic review and meta analysis
    • PMID: 23441167
    • Jiang Z, Li C, Li F, Wang X. EGFR gene copy number as a prognostic marker in colorectal cancer patients treated with cetuximab or panitumumab: a systematic review and meta analysis. PLoS One 2013; 8: e56205 [PMID: 23441167 DOI: 10.1371/journal.pone.0056205]
    • (2013) PLoS One , vol.8 , pp. e56205
    • Jiang, Z.1    Li, C.2    Li, F.3    Wang, X.4
  • 16
    • 17844362179 scopus 로고    scopus 로고
    • Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: A cohort study
    • PMID: 15863375
    • Moroni M, Veronese S, Benvenuti S, Marrapese G, Sartore-Bianchi A, Di Nicolantonio F, Gambacorta M, Siena S, Bardelli A. Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study. Lancet Oncol 2005; 6: 279-286 [PMID: 15863375 DOI: 10.1016/S1470-2045(05)70102-9]
    • (2005) Lancet Oncol , vol.6 , pp. 279-286
    • Moroni, M.1    Veronese, S.2    Benvenuti, S.3    Marrapese, G.4    Sartore-Bianchi, A.5    Di Nicolantonio, F.6    Gambacorta, M.7    Siena, S.8    Bardelli, A.9
  • 19
    • 84871879404 scopus 로고    scopus 로고
    • Antiangiogenesis therapy in the treatment of metastatic colorectal cancer
    • PMID: 23118806
    • Grothey A, Allegra C. Antiangiogenesis therapy in the treatment of metastatic colorectal cancer. Ther Adv Med Oncol 2012; 4: 301-319 [PMID: 23118806 DOI: 10.1177/1758834012454464]
    • (2012) Ther Adv Med Oncol , vol.4 , pp. 301-319
    • Grothey, A.1    Allegra, C.2
  • 20
    • 43249095919 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • PMID: 18463380
    • Kerbel RS. Tumor angiogenesis. N Engl J Med 2008; 358: 2039-2049 [PMID: 18463380 DOI: 10.1056/NEJMra0706596]
    • (2008) N Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 21
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: Mechanisms of anti-tumour activity
    • PMID: 18596824
    • Ellis LM, Hicklin DJ. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat Rev Cancer 2008; 8: 579-591 [PMID: 18596824 DOI: 10.1038/nrc2403]
    • (2008) Nat Rev Cancer , vol.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 22
    • 84879153063 scopus 로고    scopus 로고
    • Anti-VEGF agents in metastatic colorectal cancer (mCRC): Are they all alike?
    • PMID: 23807861
    • Saif MW. Anti-VEGF agents in metastatic colorectal cancer (mCRC): are they all alike? Cancer Manag Res 2013; 5: 103-115 [PMID: 23807861 DOI: 10.2147/CMAR.S45193]
    • (2013) Cancer Manag Res , vol.5 , pp. 103-115
    • Saif, M.W.1
  • 23
    • 84861382251 scopus 로고    scopus 로고
    • Intravenous (IV) aflibercept versus placebo in combination with irinotecan/5-FU (FOLFIRI) for second-line treatment of metastatic colorectal cancer (mCRC): Results of a multinational phase III trial (EFC10262-VELOUR)
    • Van Cutsem E, Tabernero J, Lakomy R, Prausova J, Ruff P, Van Hazel G. Intravenous (IV) aflibercept versus placebo in combination with irinotecan/5-FU (FOLFIRI) for second-line treatment of metastatic colorectal cancer (mCRC): Results of a multinational phase III trial (EFC10262-VELOUR). Ann Oncol 2011; 22 suppl 5: 18 [DOI: 10.1093/annonc/mdr285]
    • (2011) Ann Oncol , vol.22 , pp. 18
    • Van Cutsem, E.1    Tabernero, J.2    Lakomy, R.3    Prausova, J.4    Ruff, P.5    Van Hazel, G.6
  • 24
    • 84865243485 scopus 로고    scopus 로고
    • Overcoming resistance to antiangiogenic therapies
    • PMID: 22773560
    • Tejpar S, Prenen H, Mazzone M. Overcoming resistance to antiangiogenic therapies. Oncologist 2012; 17: 1039-1050 [PMID: 22773560 DOI: 10.1634/theoncologist.2012-0068]
    • (2012) Oncologist , vol.17 , pp. 1039-1050
    • Tejpar, S.1    Prenen, H.2    Mazzone, M.3
  • 25
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • PMID: 14744438
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297 [PMID: 14744438]
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 26
    • 71049136170 scopus 로고    scopus 로고
    • MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application
    • PMID: 19912656
    • Slaby O, Svoboda M, Michalek J, Vyzula R. MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer 2009; 8: 102 [PMID: 19912656 DOI: 10.1186/1476-4598-8-102]
    • (2009) Mol Cancer , vol.8 , pp. 102
    • Slaby, O.1    Svoboda, M.2    Michalek, J.3    Vyzula, R.4
  • 27
    • 52449115337 scopus 로고    scopus 로고
    • MicroRNAs in development and disease
    • PMID: 18713256
    • Erson AE, Petty EM. MicroRNAs in development and disease. Clin Genet 2008; 74: 296-306 [PMID: 18713256 DOI: 10.1111/j.1399-0004.2008.01076.x]
    • (2008) Clin Genet , vol.74 , pp. 296-306
    • Erson, A.E.1    Petty, E.M.2
  • 30
    • 84880223123 scopus 로고    scopus 로고
    • The role of microRNAs in breast cancer stem cells
    • PMID: 23860207
    • Schwarzenbacher D, Balic M, Pichler M. The role of microRNAs in breast cancer stem cells. Int J Mol Sci 2013; 14: 14712-14723 [PMID: 23860207 DOI: 10.3390/ijms140714712]
    • (2013) Int J Mol Sci , vol.14 , pp. 14712-14723
    • Schwarzenbacher, D.1    Balic, M.2    Pichler, M.3
  • 32
    • 84867015470 scopus 로고    scopus 로고
    • MicroRNAs in renal cell carcinoma: Implications for pathogenesis, diagnosis, prognosis and therapy
    • PMID: 22993312
    • Al-Ali BM, Ress AL, Gerger A, Pichler M. MicroRNAs in renal cell carcinoma: implications for pathogenesis, diagnosis, prognosis and therapy. Anticancer Res 2012; 32: 3727-3732 [PMID: 22993312]
    • (2012) Anticancer Res , vol.32 , pp. 3727-3732
    • Al-Ali, B.M.1    Ress, A.L.2    Gerger, A.3    Pichler, M.4
  • 33
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • PMID: 17898713
    • Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 2007; 449: 682-688 [PMID: 17898713 DOI: 10.1038/nature06174]
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 35
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • PMID: 15531879
    • Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ. Processing of primary microRNAs by the Microprocessor complex. Nature 2004; 432: 231-235 [PMID: 15531879 DOI: 10.1038/nature03049]
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 36
    • 77955593347 scopus 로고    scopus 로고
    • microRNA: A master regulator of cellular processes for bioengineering systems
    • PMID: 20415587
    • Sun W, Julie Li YS, Huang HD, Shyy JY, Chien S. microRNA: a master regulator of cellular processes for bioengineering systems. Annu Rev Biomed Eng 2010; 12: 1-27 [PMID: 20415587 DOI: 10.1146/annurev-bioeng-070909-105314]
    • (2010) Annu Rev Biomed Eng , vol.12 , pp. 1-27
    • Sun, W.1    Julie Li, Y.S.2    Huang, H.D.3    Shyy, J.Y.4    Chien, S.5
  • 37
    • 77954386625 scopus 로고    scopus 로고
    • MicroRNAs, ultraconserved genes and colorectal cancers
    • PMID: 19497386
    • Rossi S, Kopetz S, Davuluri R, Hamilton SR, Calin GA. MicroRNAs, ultraconserved genes and colorectal cancers. Int J Biochem Cell Biol 2010; 42: 1291-1297 [PMID: 19497386 DOI: 10.1016/j.biocel.2009.05.018]
    • (2010) Int J Biochem Cell Biol , vol.42 , pp. 1291-1297
    • Rossi, S.1    Kopetz, S.2    Davuluri, R.3    Hamilton, S.R.4    Calin, G.A.5
  • 38
    • 84861454572 scopus 로고    scopus 로고
    • Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer
    • PMID: 22549179
    • Pichler M, Winter E, Stotz M, Eberhard K, Samonigg H, Lax S, Hoefler G. Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer. Br J Cancer 2012; 106: 1826-1832 [PMID: 22549179 DOI: 10.1038/bjc.2012.175]
    • (2012) Br J Cancer , vol.106 , pp. 1826-1832
    • Pichler, M.1    Winter, E.2    Stotz, M.3    Eberhard, K.4    Samonigg, H.5    Lax, S.6    Hoefler, G.7
  • 39
    • 84894255801 scopus 로고    scopus 로고
    • miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor
    • PMID: 24098024
    • Pichler M, Winter E, Ress AL, Bauernhofer T, Gerger A, Kiesslich T, Lax S, Samonigg H, Hoefler G. miR-181a is associated with poor clinical outcome in patients with colorectal cancer treated with EGFR inhibitor. J Clin Pathol 2014; 67: 198-203 [PMID: 24098024 DOI: 10.1136/jclin-path-2013-201904]
    • (2014) J Clin Pathol , vol.67 , pp. 198-203
    • Pichler, M.1    Winter, E.2    Ress, A.L.3    Bauernhofer, T.4    Gerger, A.5    Kiesslich, T.6    Lax, S.7    Samonigg, H.8    Hoefler, G.9
  • 40
    • 77955478900 scopus 로고    scopus 로고
    • miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation
    • PMID: 20647341
    • Boni V, Bitarte N, Cristobal I, Zarate R, Rodriguez J, Maiello E, Garcia-Foncillas J, Bandres E. miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation. Mol Cancer Ther 2010; 9: 2265-2275 [PMID: 20647341 DOI: 10.1158/1535-7163.MCT-10-0061]
    • (2010) Mol Cancer Ther , vol.9 , pp. 2265-2275
    • Boni, V.1    Bitarte, N.2    Cristobal, I.3    Zarate, R.4    Rodriguez, J.5    Maiello, E.6    Garcia-Foncillas, J.7    Bandres, E.8
  • 48
    • 84857942226 scopus 로고    scopus 로고
    • The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer
    • PMID: 22397399
    • Hansen TF, Sørensen FB, Lindebjerg J, Jakobsen A. The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer. BMC Cancer 2012; 12: 83 [PMID: 22397399 DOI: 10.1186/1471-2407-12-83]
    • (2012) BMC Cancer , vol.12 , pp. 83
    • Hansen, T.F.1    Sørensen, F.B.2    Lindebjerg, J.3    Jakobsen, A.4
  • 49
    • 52249096359 scopus 로고    scopus 로고
    • The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
    • PMID: 18663744
    • Guo C, Sah JF, Beard L, Willson JK, Markowitz SD, Guda K. The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 2008; 47: 939-946 [PMID: 18663744 DOI: 10.1002/gcc.20596]
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 939-946
    • Guo, C.1    Sah, J.F.2    Beard, L.3    Willson, J.K.4    Markowitz, S.D.5    Guda, K.6
  • 52
    • 84883742865 scopus 로고    scopus 로고
    • MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial
    • PMID: 23922111
    • Hansen TF, Christensen Rd, Andersen RF, Sørensen FB, Johnsson A, Jakobsen A. MicroRNA-126 and epidermal growth factor-like domain 7-an angiogenic couple of importance in metastatic colorectal cancer. Results from the Nordic ACT trial. Br J Cancer 2013; 109: 1243-1251 [PMID: 23922111 DOI: 10.1038/bjc.2013.448]
    • (2013) Br J Cancer , vol.109 , pp. 1243-1251
    • Hansen, T.F.1    Rd, C.2    Andersen, R.F.3    Sørensen, F.B.4    Johnsson, A.5    Jakobsen, A.6
  • 53
    • 78049511518 scopus 로고    scopus 로고
    • Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells
    • PMID: 21062447
    • Wang CJ, Stratmann J, Zhou ZG, Sun XF. Suppression of microRNA-31 increases sensitivity to 5-FU at an early stage, and affects cell migration and invasion in HCT-116 colon cancer cells. BMC Cancer 2010; 10: 616 [PMID: 21062447 DOI: 10.1186/1471-2407-10-616]
    • (2010) BMC Cancer , vol.10 , pp. 616
    • Wang, C.J.1    Stratmann, J.2    Zhou, Z.G.3    Sun, X.F.4
  • 54
    • 84862932892 scopus 로고    scopus 로고
    • microRNA-192, -194 and -215 are frequently downregulated in colorectal cancer
    • PMID: 22969930
    • Chiang Y, Song Y, Wang Z, Liu Z, Gao P, Liang J, Zhu J, Xing C, Xu H. microRNA-192, -194 and -215 are frequently downregulated in colorectal cancer. Exp Ther Med 2012; 3: 560-566 [PMID: 22969930 DOI: 10.3892/etm.2011.436]
    • (2012) Exp Ther Med , vol.3 , pp. 560-566
    • Chiang, Y.1    Song, Y.2    Wang, Z.3    Liu, Z.4    Gao, P.5    Liang, J.6    Zhu, J.7    Xing, C.8    Xu, H.9
  • 57
    • 80053987030 scopus 로고    scopus 로고
    • MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer
    • PMID: 21455217
    • Zhang H, Li Y, Huang Q, Ren X, Hu H, Sheng H, Lai M. MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. Cell Death Differ 2011; 18: 1702-1710 [PMID: 21455217 DOI: 10.1038/cdd.2011.28]
    • (2011) Cell Death Differ , vol.18 , pp. 1702-1710
    • Zhang, H.1    Li, Y.2    Huang, Q.3    Ren, X.4    Hu, H.5    Sheng, H.6    Lai, M.7
  • 58
    • 84867048400 scopus 로고    scopus 로고
    • The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer
    • PMID: 23056401
    • Takahashi M, Cuatrecasas M, Balaguer F, Hur K, Toiyama Y, Castells A, Boland CR, Goel A. The clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancer. PLoS One 2012; 7: e46684 [PMID: 23056401 DOI: 10.1371/journal.pone.0046684]
    • (2012) PLoS One , vol.7 , pp. e46684
    • Takahashi, M.1    Cuatrecasas, M.2    Balaguer, F.3    Hur, K.4    Toiyama, Y.5    Castells, A.6    Boland, C.R.7    Goel, A.8
  • 59
    • 84892993914 scopus 로고    scopus 로고
    • Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment
    • PMID: 24119443
    • Kjersem JB, Ikdahl T, Lingjaerde OC, Guren T, Tveit KM, Kure EH. Plasma microRNAs predicting clinical outcome in metastatic colorectal cancer patients receiving first-line oxaliplatin-based treatment. Mol Oncol 2014; 8: 59-67 [PMID: 24119443 DOI: 10.1016/j.molonc.2013.09.001]
    • (2014) Mol Oncol , vol.8 , pp. 59-67
    • Kjersem, J.B.1    Ikdahl, T.2    Lingjaerde, O.C.3    Guren, T.4    Tveit, K.M.5    Kure, E.H.6
  • 61
    • 84893669133 scopus 로고    scopus 로고
    • Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro
    • PMID: 24275137
    • Deng J, Lei W, Fu JC, Zhang L, Li JH, Xiong JP. Targeting miR-21 enhances the sensitivity of human colon cancer HT-29 cells to chemoradiotherapy in vitro. Biochem Biophys Res Commun 2014; 443: 789-795 [PMID: 24275137 DOI: 10.1016/j.bbrc.2013.11.064]
    • (2014) Biochem Biophys Res Commun , vol.443 , pp. 789-795
    • Deng, J.1    Lei, W.2    Fu, J.C.3    Zhang, L.4    Li, J.H.5    Xiong, J.P.6
  • 63
    • 84879621292 scopus 로고    scopus 로고
    • miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer
    • PMID: 23744359
    • Karaayvaz M, Zhai H, Ju J. miR-129 promotes apoptosis and enhances chemosensitivity to 5-fluorouracil in colorectal cancer. Cell Death Dis 2013; 4: e659 [PMID: 23744359 DOI: 10.1038/cddis.2013.193]
    • (2013) Cell Death Dis , vol.4 , pp. e659
    • Karaayvaz, M.1    Zhai, H.2    Ju, J.3
  • 65
    • 34548215742 scopus 로고    scopus 로고
    • Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro
    • PMID: 17702597
    • Rossi L, Bonmassar E, Faraoni I. Modification of miR gene expression pattern in human colon cancer cells following exposure to 5-fluorouracil in vitro. Pharmacol Res 2007; 56: 248-253 [PMID: 17702597 DOI: 10.1016/j.phrs.2007.07.001]
    • (2007) Pharmacol Res , vol.56 , pp. 248-253
    • Rossi, L.1    Bonmassar, E.2    Faraoni, I.3
  • 66
    • 34848868157 scopus 로고    scopus 로고
    • Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells
    • PMID: 17875987
    • Tazawa H, Tsuchiya N, Izumiya M, Nakagama H. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells. Proc Natl Acad Sci USA 2007; 104: 15472-15477 [PMID: 17875987 DOI: 10.1073/pnas.0707351104]
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 15472-15477
    • Tazawa, H.1    Tsuchiya, N.2    Izumiya, M.3    Nakagama, H.4
  • 67
    • 78649633708 scopus 로고    scopus 로고
    • Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells
    • PMID: 21067862
    • Akao Y, Noguchi S, Iio A, Kojima K, Takagi T, Naoe T. Dysregulation of microRNA-34a expression causes drug-resistance to 5-FU in human colon cancer DLD-1 cells. Cancer Lett 2011; 300: 197-204 [PMID: 21067862 DOI: 10.1016/j.canlet.2010.10.006]
    • (2011) Cancer Lett , vol.300 , pp. 197-204
    • Akao, Y.1    Noguchi, S.2    Iio, A.3    Kojima, K.4    Takagi, T.5    Naoe, T.6
  • 70
    • 70350433121 scopus 로고    scopus 로고
    • MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells
    • PMID: 19843160
    • Borralho PM, Kren BT, Castro RE, da Silva IB, Steer CJ, Rodrigues CM. MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. FEBS J 2009; 276: 6689-6700 [PMID: 19843160 DOI: 10.1111/j.1742-4658.2009.07383.x]
    • (2009) FEBS J , vol.276 , pp. 6689-6700
    • Borralho, P.M.1    Kren, B.T.2    Castro, R.E.3    Da Silva, I.B.4    Steer, C.J.5    Rodrigues, C.M.6
  • 72
    • 84881551103 scopus 로고    scopus 로고
    • MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis
    • PMID: 22735571
    • Hur K, Toiyama Y, Takahashi M, Balaguer F, Nagasaka T, Koike J, Hemmi H, Koi M, Boland CR, Goel A. MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis. Gut 2013; 62: 1315-1326 [PMID: 22735571 DOI: 10.1136/gutjnl-2011-301846]
    • (2013) Gut , vol.62 , pp. 1315-1326
    • Hur, K.1    Toiyama, Y.2    Takahashi, M.3    Balaguer, F.4    Nagasaka, T.5    Koike, J.6    Hemmi, H.7    Koi, M.8    Boland, C.R.9    Goel, A.10
  • 73
    • 84895923572 scopus 로고    scopus 로고
    • Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer
    • PMID: 23982750
    • Toiyama Y, Hur K, Tanaka K, Inoue Y, Kusunoki M, Boland CR, Goel A. Serum miR-200c is a novel prognostic and metastasis-predictive biomarker in patients with colorectal cancer. Ann Surg 2014; 259: 735-743 [PMID: 23982750 DOI: 10.1097/SLA.0b013e3182a6909d]
    • (2014) Ann Surg , vol.259 , pp. 735-743
    • Toiyama, Y.1    Hur, K.2    Tanaka, K.3    Inoue, Y.4    Kusunoki, M.5    Boland, C.R.6    Goel, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.