Gastrointestinal hormones and their targets

Advances in Experimental Medicine and Biology

Volumn 817, Issue , 2014, Pages 157-175

  Rehfeld, Jens F ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; F FACTOR; G PROTEIN COUPLED RECEPTOR; GASTRIC INHIBITORY POLYPEPTIDE; GASTRIN; GASTROINTESTINAL HORMONE; GHRELIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; GROWTH FACTOR; GROWTH HORMONE RELEASING FACTOR; HORMONE; HORMONE PRECURSOR; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; INSULIN; MOTILIN; NEUROKININ A; NEUROKININ B; NEUROPEPTIDE Y; NEUROTRANSMITTER; OBESTATIN; PANCREAS POLYPEPTIDE; PEPTIDE HISTIDINE ISOLEUCINE; PEPTIDE YY; RELAXIN; SECRETIN; SOMATOSTATIN; SUBSTANCE P; VASOACTIVE INTESTINAL POLYPEPTIDE; PROTEIN PRECURSOR;

ALTERNATIVE RNA SPLICING; ARTICLE; AUTOCRINE EFFECT; CANCER CELL; CELL MEMBRANE; DIGESTIVE SYSTEM; ENDOCRINE CELL; ENTEROENDOCRINE CELL; GASTROINTESTINAL TRACT; GENE EXPRESSION; HORMONE RELEASE; HORMONE SYNTHESIS; HUMAN; NERVE CELL; NEUROSECRETORY CELL; PARACRINE SIGNALING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPERMATOZOON; STRUCTURAL HOMOLOGY; TARGET CELL; ANIMAL; GENETICS; METABOLISM; PHYSIOLOGY; REVIEW;

ANIMALS; GASTROINTESTINAL HORMONES; GENE EXPRESSION; HUMANS; PROTEIN PRECURSORS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84909606800     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-1-4939-0897-4_7     Document Type: Article

References (63)

1. Bayliss WM, Starling EH (1902) The mechanism of pancreatic secretion. J Physiol 28 (5):325-353
2. Edkins JS (1906) The chemical mechanism of gastric secretion. J Physiol 34(1-2):133-144
3. Starling EH (1905) The Croonian lecture on the chemical correlation of the function of the body. Lancet II:399-341
4. Ivy AC, Oldberg E (1928) A hormone mechanism for gallbladder contraction and evacuation. Am J Physiol 86:599-613
5. Harper AA, Raper HS (1943) Pancreozymin, a stimulation of the secretion of pancreatic enzymes in extracts of the small intestine. J Physiol 102(1):115-125
6. Jorpes JE, Mutt V (1966) Cholecystokinin and pancreozymin, one single hormone? Acta Physiol Scand 66(1):196-202
7. Rehfeld JF (1998) The new biology of gastrointestinal hormones. Physiol Rev 78 (4):1087-1108
8. Rehfeld JF (2004) A centenary of gastrointestinal endocrinology. Horm Metab Res 36 (11-12):735-741
9. Schultz SG, Mackhlouf GM, Rauner BB (eds) (1989) Handbook of physiology. The gastrointestinal system. Neural and endocrine biology. American Physiology Society, Bethesda
10. Walsh JH, Dockray GJ (eds) (1994) Gut peptides. Raven, New York
11. Taché Y, Goto Y, Ohning G (eds) (2002) Gut-brain peptides in the new millennium. Cure Foundation, Los Angeles
12. Rehfeld JF (2012) Beginnings: a reflection on the history of gastrointestinal endocrinology. Regul Pept 177(Suppl):S1-S5
13. Amara SG, Jonas V, Rosenfeld MG, Onges ES, Evans RM (1982) Alternative RNA processing in calcitonin gene expression generates mRNAs encoding different polypeptide products. Nature 298(5871):240-244
14. Gafvelin G, Jörnvall H, Mutt V (1990) Processing of prosecretin: isolation of a secretin precursor from porcine intestine. Proc Natl Acad Sci U S A 87(17):6781-6785
15. Kopin AS, Wheeler MB, Nishtani J, McBride EW, Chang TM, Chey WY et al (1991) The secretin gene: evolutionary history, alternative splicing and developmental regulation. Proc Natl Acad Sci U S A 88(12):5335-5339
16. Rehfeld JF (2011) Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: cholecystokinin and gastrin peptides. Acta Physiol (Oxf) 201 (4):405-411
17. Persson P, Håkanson R, Axelson J, Sundler F (1989) Gastrin releases a blood-calcium lowering peptide from the acid producing part of the stomach. Proc Natl Acad Sci U S A 86 (8):2834-2838
18. Kronenberg HM, Lanske B, Kovacs CS, Chung UI, Lee K, Segre GV, Schipani E, Jüppner H (1998) Functional analysis of the PTH/PTHrP network of ligands and receptors. Recent Prog Horm Res 53:283-301
19. Glover ID, Barlow DJ, Pitts JE, Wood SP, Tickle IJ, Blundell TL et al (1984) Conformational studies on the pancreatic polypeptide hormone family. Eur J Biochem 142(2):379-385
20. Johnsen AH, Rehfeld JF (1990) Cionin: a di-sulfotyrosyl hybrid of cholecystokinin and gastrin from the protochordate Ciona intestinalis. J Biol Chem 265(6):3054-3058
21. Anastasi A, Erspamer V, Endean R (1968) Isolation and amino acid sequence of caerulein, the active decapeptide of the skin of hyla caerulea. Arch Biochem Biophys 125(1):57-68
22. Doolittle RF, Feng DF, Tsang S, Cho G, Little E (1996) Determining divergence times of the major kingdoms of living organisms with a protein clock. Science 271(5248):470-477
23. Johnsen AH (1998) Phylogeny of the cholecystokinin/gastrin family. Front Neuroendocrinol 19(2):73-99
24. Rourke IJ, Rehfeld JF, Møller M, Johnsen AH (1997) Characterization of the cholecystokinin and gastrin genes from the bullfrog, Rana catesbeiana: evolutionary conservation of primary and secondary sites of gene expression. Endocrinology 138(4):1719-1727
25. Holzer P (1994) Calcitonin gene-related peptide. In: Walsh JH, Dockray GJ (eds) Gut peptides: biochemistry and physiology. Raven, New York, pp 493-534
26. Nawa H, Kotani H, Nakanishi S (1984) Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing. Nature 312(5996):729-734
27. Mutt V, Jorpes JE, Magnusson S (1970) Structure of porcine secretin. The amino acid sequence. Eur J Biochem 15(3):513-519
28. Dockray GJ, Varro A, Dimaline R, Wang T (2001) The gastrins: their production and biological activities. Annu Rev Physiol 63:119-139
29. Ørskov C, Bersani M, Johnsen AH, Højrup P, Holst JJ (1989) Complete sequences of glucagon-like peptide-1 from human and pig small intestine. J Biol Chem 264 (22):12826-12829
30. Drucker DJ, Erlich P, Asa SL, Brubaker PL (1996) Induction of intestinal epithelial proliferation by glucagon-like peptide 2. Proc Natl Acad Sci U S A 93(15):7911-7916
31. Holst JJ, Ørskov C, Nielsen OV, Schwartz TW (1987) Truncated glucagon-like peptide-I, an insulin-releasing hormone from the distal gut. FEBS Lett 211(2):169-174
32. Bell GI, Santerre RF, Müllenbach GT (1983) Hamster preproglucagon contains the sequence of glucagon and two related peptides. Nature 302(5910):716-718
33. Mojsov S, Weir GC, Habener JF (1987) Insulintropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas. J Clin Invest 79(2):616-619
34. Rehfeld JF (1990) Posttranslational attenuation of peptide gene expression. FEBS Lett 268 (1):1-4
35. Lüttichau HR, van Solinge WW, Nielsen FC, Rehfeld JF (1993) Developmental expression of the gastrin and cholecystokinin genes in rat colon. Gastroenterology 104(4):1092-1098
36. Larsson LI, Rehfeld JF, Sundler F, Håkanson R (1976) Pancreatic gastrin in foetal and neonatal rats. Nature 262(5569):609-610
37. Bardram L, Hilsted L, Rehfeld JF (1990) Progastrin expression in mammalian pancreas. Proc Natl Acad Sci U S A 87(1):298-302
38. Rehfeld JF (1978) Localisation of gastrins to neuro- and adenohypophysis. Nature 271 (5647):771-773
39. Larsson LI, Rehfeld JF (1981) Pituitary gastrins occur in corticotrophs and melanotrophs. Science 213(4509):768-770
40. Rehfeld JF, Hansen HF, Larsson LI, Stengaard-Pedersen K, Thorn NA (1984) Gastrin and cholecystokinin in pituitary neurons. Proc Natl Acad Sci U S A 81(6):1902-1905
41. Uvnäs-Wallensten K, Rehfeld JF, Larsson LI, Uvnäs B (1977) Heptadecapeptide gastrin in the vagal nerve. Proc Natl Acad Sci U S A 74(12):5707-5710
42. Schalling M, Persson H, Pelto-Huikko M, Odum L, Ekman P, Gottlieb C et al (1990) Expression and localization of gastrin messenger RNA and peptide in human spermatogenetic cells. J Clin Invest 86(2):660-669
43. Bundgaard JR, Vuust J, Rehfeld JF (1995) Tyrosine O-sulfation promotes proteolytic processing of progastrin. EMBO J 14(13):3073-3079
44. Larsson LI, Goltermann N, de Magistris L, Rehfeld JF, Schwartz TW (1979) Somatostatin cell processes as pathways for paracrine secretion. Science 205(4413):1393-1395
45. Sporn MB, Roberts AB (1985) Autocrine growth factors and cancer. Nature 313 (6005):745-747
46. Cuttitta F, Carney DN, Mulshine J, Moody TW, Fedorko J, Fischler A et al (1985) Bombesinlike peptides can function as autocrine growth factors in human small-cell lung cancer. Nature 316(6031):823-826
47. Layton JE, Scanlon DB, Soveny C, Mostyn G (1988) Effects of Bombesin antagonists on the growth of small cell lung cancer cells in vitro. Cancer Res 48(17):4783-4789
48. Sethi T, Rozengurt E (1992) Gastrin stimulates Ca2 + -mobilization and clonal growth in small cell lung cancer cells. Cancer Res 52(21):6031-6035
49. Blackmore M, Hirst BH (1992) Autocrine stimulation of growth of AR4-2J rat pancreatic tumour cells by gastrin. Br J Cancer 66(1):32-38
50. Weinstock J, Baldwin GS (1988) Binding of gastrin(17) to human gastric carcinoma cell lines. Cancer Res 48(4):932-937
51. Hoosein NM, Kiener PA, Curry RC, Brattain MG (1990) Evidence for autocrine growth stimulation of cultured colon tumor cells by gastrin/cholecystokinin-like peptide. Exp Cell Res 186(1):15-21
52. Heald EB, Kramer ST, Smith JP (1992) Trophic effects of unsulfated cholecystokinin on mouse pancreas and human pancreatic cancer. Pancreas 7(5):530-535
53. Persson H, Rehfeld JF, Ericsson A, Schalling M, Pelto-Huikko M, Hökfelt T (1989) Transient expression on the cholecystokinin gene in male germ cells and accumulation of the peptide in the acrosomal granule: possible role of cholecystokinin in fertilization. Proc Natl Acad Sci U S A 86(16):6166-6170
54. Li M, Mbikay M, Nakayama K, Miyata A, Arimura A (2000) Prohormone convertase PC4 processes the precursor of PACAP in the testis. Ann N Y Acad Sci 921:333-339
55. Shintani N, Mori W, Hashimoto H, Imai M, Tanaka K, Tomomoto S et al (2002) Defects in reproductive functions in PACAP-deficient female mice. Regul Pept 109(1-3):45-48
56. Reubi JC (2003) Peptide receptors as molecular targets for cancer diagnosis and therapy. Endocr Rev 24(4):389-427
57. Körner M, Eltschinger V, Waser B, Schönbrunn A, Reubi JC (2005) Value of immunohistochemistry for somatostatin receptor subtype sst2A in cancer tissuer: lessons from the comparison of anti-sst2A antibodies with somatostatin receptor autoradiography. Am J Surg Pathol 29 (12):1642-1651
58. Volante M, Brizzi MP, Faggiano A, La Rosa S, Rapa I, Ferrero A et al (2007) Somatostatin receptor type 2A immunohistochemistry in neuroendocrine tumors: a proposal of scoring system correlated with somatostatin receptor scintigraphy. Mod Pathol 20(11):1172-1182
59. Fischer T, Doll C, Jacobs S, Kolodziej A, Stumm R, Schulz S (2008) Reassessment of sst2 somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-1. J Clin Endocrinol Metab 93(11):4519-4524
60. Körner M, Waser B, Schönbrunn A, Perren A, Reubi JC (2012) Somatostatin receptor subtype 2A immunohistochemistry using a new monoclonal antibody selects tumors suitable for in vivo somatostatin receptor targeting. Am J Surg Pathol 36(2):242-252
61. Lupp A, Hunder A, Petrich A, Nagel F, Doll C, Schulz S (2011) Reassessment of sst (5) somatostatin receptor expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-4. Neuroendocrinology 94(3):255-264
62. Pyke C, Knudsen LB (2013) The glucagon-like peptide-1 receptor - or not? Endocrinology 154(1):4-8
63. Michel MC, Wieland T, Tsujimoto G (2009) How reliable are G-protein-coupled receptor antibodies? Naunyn Schmiedebergs Arch Pharmacol 379(4):385-388