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Volumn 201, Issue 4, 2011, Pages 405-411

Incretin physiology beyond glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide: Cholecystokinin and gastrin peptides

Author keywords

Cholecystokinin; Gastrin; Glucagon like peptide 1; Glucose dependent insulinotropic polypeptide; Incretin; Insulin

Indexed keywords

CHOLECYSTOKININ; GASTRIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INCRETIN;

EID: 79952512270     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2010.02235.x     Document Type: Review
Times cited : (78)

References (73)
  • 1
    • 0024213841 scopus 로고
    • Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig
    • Ahrén, B., Martensson, H. & Nobin, A. 1988. Cholecystokinin (CCK)-4 and CCK-8 stimulate islet hormone secretion in vivo in the pig. Pancreas 3, 279-284.
    • (1988) Pancreas , vol.3 , pp. 279-284
    • Ahrén, B.1    Martensson, H.2    Nobin, A.3
  • 2
    • 0021989365 scopus 로고
    • Nesidioblastosis and islet cell changes related to endogenous hypergastrinemia
    • Bani, S.T., Bani, D. & Biliotti, G. 1985. Nesidioblastosis and islet cell changes related to endogenous hypergastrinemia. Virchows Arch B Cell Pathol Incl Mol Pathol 48, 261-276.
    • (1985) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.48 , pp. 261-276
    • Bani, S.T.1    Bani, D.2    Biliotti, G.3
  • 3
    • 0024999420 scopus 로고
    • Gastrin in non-neoplastic pancreatic tissue from patients with and without gastrinomas
    • Bardram, L. 1990. Gastrin in non-neoplastic pancreatic tissue from patients with and without gastrinomas. Scand J Gastroenterol 25, 935-943.
    • (1990) Scand J Gastroenterol , vol.25 , pp. 935-943
    • Bardram, L.1
  • 5
    • 84944484435 scopus 로고
    • The mechanism of pancreatic secretion
    • Bayliss, W.M. & Starling, E.H. 1902. The mechanism of pancreatic secretion. J Physiol 28, 325-353.
    • (1902) J Physiol , vol.28 , pp. 325-353
    • Bayliss, W.M.1    Starling, E.H.2
  • 6
    • 33748442464 scopus 로고    scopus 로고
    • Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82weeks in 314 overweight patients with type 2 diabetes
    • Blonde, L., Klein, E.J., Han, J., Zhang, B., Mac, S.M., Poon, T.H., Taylor, K.L., Trautmann, M.E., Kim, D.D. & Kendall, D.M. 2006. Interim analysis of the effects of exenatide treatment on A1C, weight and cardiovascular risk factors over 82weeks in 314 overweight patients with type 2 diabetes. Diabetes Obes Metab 8, 436-447.
    • (2006) Diabetes Obes Metab , vol.8 , pp. 436-447
    • Blonde, L.1    Klein, E.J.2    Han, J.3    Zhang, B.4    Mac, S.M.5    Poon, T.H.6    Taylor, K.L.7    Trautmann, M.E.8    Kim, D.D.9    Kendall, D.M.10
  • 7
    • 0021278513 scopus 로고
    • Complete tyrosine-O-sulphation of gastrin in neonatal rat pancreas
    • Brand, S.J., Andersen, B.N. & Rehfeld, J.F. 1984. Complete tyrosine-O-sulphation of gastrin in neonatal rat pancreas. Nature 309, 456-458.
    • (1984) Nature , vol.309 , pp. 456-458
    • Brand, S.J.1    Andersen, B.N.2    Rehfeld, J.F.3
  • 8
    • 0036968693 scopus 로고    scopus 로고
    • Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin
    • Brand, S.J., Tagerud, S., Lambert, P., Magil, S.G., Tatarkiewicz, K., Doiron, K. & Yan, Y. 2002. Pharmacological treatment of chronic diabetes by stimulating pancreatic beta-cell regeneration with systemic co-administration of EGF and gastrin. Pharmacol Toxicol 91, 414-420.
    • (2002) Pharmacol Toxicol , vol.91 , pp. 414-420
    • Brand, S.J.1    Tagerud, S.2    Lambert, P.3    Magil, S.G.4    Tatarkiewicz, K.5    Doiron, K.6    Yan, Y.7
  • 9
    • 0023053042 scopus 로고
    • Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas
    • Cantor, P., Andersen, B.N. & Rehfeld, J.F. 1986. Complete tyrosine O-sulfation of gastrin in adult and neonatal cat pancreas. FEBS Lett 195, 272-274.
    • (1986) FEBS Lett , vol.195 , pp. 272-274
    • Cantor, P.1    Andersen, B.N.2    Rehfeld, J.F.3
  • 10
    • 0032538298 scopus 로고    scopus 로고
    • Novel aspects of gastrin-induced activation of histidine decarboxylase in rat stomach ECL cells
    • Chen, D., Zhao, C.M., Yamada, H., Norlen, P. & Håkanson, R. 1998. Novel aspects of gastrin-induced activation of histidine decarboxylase in rat stomach ECL cells. Regul Pept 77, 169-175.
    • (1998) Regul Pept , vol.77 , pp. 169-175
    • Chen, D.1    Zhao, C.M.2    Yamada, H.3    Norlen, P.4    Håkanson, R.5
  • 12
    • 53749085064 scopus 로고    scopus 로고
    • Incretin-based therapies in type 2 diabetes mellitus
    • Chia, W.C. & Egan, J.M. 2008. Incretin-based therapies in type 2 diabetes mellitus. J Clin Endocrinol Metab 93, 3703-3716.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 3703-3716
    • Chia, W.C.1    Egan, J.M.2
  • 13
    • 15044352155 scopus 로고    scopus 로고
    • The (pre-)history of the incretin concept
    • Creutzfeldt, W. 2005. The (pre-)history of the incretin concept. Regul Pept 128, 87-91.
    • (2005) Regul Pept , vol.128 , pp. 87-91
    • Creutzfeldt, W.1
  • 14
    • 2342599057 scopus 로고    scopus 로고
    • One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes
    • Degn, K.B., Juhl, C.B., Sturis, J., Jakobsen, G., Brock, B., Chandramouli, V., Rungby, J., Landau, B.R. & Schmitz, O. 2004. One week's treatment with the long-acting glucagon-like peptide 1 derivative liraglutide (NN2211) markedly improves 24-h glycemia and alpha- and beta-cell function and reduces endogenous glucose release in patients with type 2 diabetes. Diabetes 53, 1187-1194.
    • (2004) Diabetes , vol.53 , pp. 1187-1194
    • Degn, K.B.1    Juhl, C.B.2    Sturis, J.3    Jakobsen, G.4    Brock, B.5    Chandramouli, V.6    Rungby, J.7    Landau, B.R.8    Schmitz, O.9
  • 15
    • 0018101373 scopus 로고
    • Isolation, structure and biological activity of two cholecystokinin octapeptides from sheep brain
    • Dockray, G.J., Gregory, R.A., Hutchison, J.B., Harris, J.I. & Runswick, M.J. 1978. Isolation, structure and biological activity of two cholecystokinin octapeptides from sheep brain. Nature 274, 711-713.
    • (1978) Nature , vol.274 , pp. 711-713
    • Dockray, G.J.1    Gregory, R.A.2    Hutchison, J.B.3    Harris, J.I.4    Runswick, M.J.5
  • 16
    • 33644618433 scopus 로고    scopus 로고
    • The biology of incretin hormones
    • Drucker, D.J. 2006. The biology of incretin hormones. Cell Metab 3, 153-165.
    • (2006) Cell Metab , vol.3 , pp. 153-165
    • Drucker, D.J.1
  • 17
    • 33644841711 scopus 로고    scopus 로고
    • Cholecystokinin and gastrin receptors
    • Dufresne, M., Seva, C. & Fourmy, D. 2006. Cholecystokinin and gastrin receptors. Physiol Rev 86, 805-847.
    • (2006) Physiol Rev , vol.86 , pp. 805-847
    • Dufresne, M.1    Seva, C.2    Fourmy, D.3
  • 18
    • 0014494844 scopus 로고
    • Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man
    • Dupre, J., Curtis, J.D., Unger, R.H., Waddell, R.W. & Beck, J.C. 1969. Effects of secretin, pancreozymin, or gastrin on the response of the endocrine pancreas to administration of glucose or arginine in man. J Clin Invest 48, 745-757.
    • (1969) J Clin Invest , vol.48 , pp. 745-757
    • Dupre, J.1    Curtis, J.D.2    Unger, R.H.3    Waddell, R.W.4    Beck, J.C.5
  • 19
    • 33845344395 scopus 로고
    • Plasma insulin responses to oral and intravenous glucose administration
    • Elrick, H., Stimmler, L., Hlad, C.J. & Arai, Y. 1964. Plasma insulin responses to oral and intravenous glucose administration. J Clin Endocrinol Metab 24, 1076-1082.
    • (1964) J Clin Endocrinol Metab , vol.24 , pp. 1076-1082
    • Elrick, H.1    Stimmler, L.2    Hlad, C.J.3    Arai, Y.4
  • 20
    • 0015506435 scopus 로고
    • Isolation of two "big gastrins" from Zollinger-Ellison tumour tissue
    • Gregory, R.A. & Tracy, H.J. 1972. Isolation of two "big gastrins" from Zollinger-Ellison tumour tissue. Lancet 2, 797-799.
    • (1972) Lancet , vol.2 , pp. 797-799
    • Gregory, R.A.1    Tracy, H.J.2
  • 23
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • Holst, J.J. 2007. The physiology of glucagon-like peptide 1. Physiol Rev 87, 1409-1439.
    • (2007) Physiol Rev , vol.87 , pp. 1409-1439
    • Holst, J.J.1
  • 24
    • 0027537582 scopus 로고
    • Differential gene expression of CCK(A) and CCK(B) receptors in the rat brain
    • Honda, T., Wada, E., Battey, J.F. & Wank, S.A. 1993. Differential gene expression of CCK(A) and CCK(B) receptors in the rat brain. Mol Cell Neurosci 4, 143-154.
    • (1993) Mol Cell Neurosci , vol.4 , pp. 143-154
    • Honda, T.1    Wada, E.2    Battey, J.F.3    Wank, S.A.4
  • 25
    • 0017239340 scopus 로고
    • The trophic action of gastrointestinal hormones
    • Johnson, L.R. 1976. The trophic action of gastrointestinal hormones. Gastroenterology 70, 278-288.
    • (1976) Gastroenterology , vol.70 , pp. 278-288
    • Johnson, L.R.1
  • 26
    • 0014627556 scopus 로고
    • Effect of gastrin on the in vivo incorporation of 14C-leucine into protein of the digestive tract
    • Johnson, L.R., Aures, D. & Håkanson, R. 1969. Effect of gastrin on the in vivo incorporation of 14C-leucine into protein of the digestive tract. Proc Soc Exp Biol Med 132, 996-998.
    • (1969) Proc Soc Exp Biol Med , vol.132 , pp. 996-998
    • Johnson, L.R.1    Aures, D.2    Håkanson, R.3
  • 27
    • 0014506678 scopus 로고
    • Stimulation of insulin secretion by the C-terminal tetrapeptide amide of gastrin
    • Kaneto, A., Tasaka, Y., Kosaka, K. & Nakao, K. 1969. Stimulation of insulin secretion by the C-terminal tetrapeptide amide of gastrin. Endocrinology 84, 1098-1106.
    • (1969) Endocrinology , vol.84 , pp. 1098-1106
    • Kaneto, A.1    Tasaka, Y.2    Kosaka, K.3    Nakao, K.4
  • 28
    • 2342626059 scopus 로고    scopus 로고
    • Gastro-intestinal hormones GIP and GLP-1
    • Kieffer, T.J. 2004. Gastro-intestinal hormones GIP and GLP-1. Ann Endocrinol (Paris) 65, 13-21.
    • (2004) Ann Endocrinol (Paris) , vol.65 , pp. 13-21
    • Kieffer, T.J.1
  • 30
    • 0141523873 scopus 로고
    • Sur le possibilité d'un traitement du diabète par l'incrétine
    • La Barre, J. 1932. Sur le possibilité d'un traitement du diabète par l'incrétine. Bull Acad R Med Belg 12, 620-634.
    • (1932) Bull Acad R Med Belg , vol.12 , pp. 620-634
    • La Barre, J.1
  • 31
    • 0001101009 scopus 로고
    • Studies on the physiology of secretin
    • La Barre, J. & Still, E.U. 1930. Studies on the physiology of secretin. Am J Physiol 91, 649-653.
    • (1930) Am J Physiol , vol.91 , pp. 649-653
    • La Barre, J.1    Still, E.U.2
  • 32
    • 0018415422 scopus 로고
    • Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous system
    • Larsson, L.I. & Rehfeld, J.F. 1979a. Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous system. Brain Res 165, 201-218.
    • (1979) Brain Res , vol.165 , pp. 201-218
    • Larsson, L.I.1    Rehfeld, J.F.2
  • 33
    • 0018772116 scopus 로고
    • Peptidergic and adrenergic innervation of pancreatic ganglia
    • Larsson, L.I. & Rehfeld, J.F. 1979b. Peptidergic and adrenergic innervation of pancreatic ganglia. Scand J Gastroenterol 14, 433-437.
    • (1979) Scand J Gastroenterol , vol.14 , pp. 433-437
    • Larsson, L.I.1    Rehfeld, J.F.2
  • 35
  • 37
    • 0027460545 scopus 로고
    • The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization
    • Lee, Y.M., Beinborn, M., McBride, E.W., Lu, M., Kolakowski, L.F. Jr & Kopin, A.S. 1993. The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization. J Biol Chem 268, 8164-8169.
    • (1993) J Biol Chem , vol.268 , pp. 8164-8169
    • Lee, Y.M.1    Beinborn, M.2    Mcbride, E.W.3    Lu, M.4    Kolakowski Jr, L.F.5    Kopin, A.S.6
  • 38
    • 15044356921 scopus 로고
    • The effect of duodenal instillation of hydrochloric acid upon fasting blood sugar of dogs
    • Loew, E.R., Gray, J.S. & Ivy, A.C. 1939. The effect of duodenal instillation of hydrochloric acid upon fasting blood sugar of dogs. Am J Physiol 126, 270-276.
    • (1939) Am J Physiol , vol.126 , pp. 270-276
    • Loew, E.R.1    Gray, J.S.2    Ivy, A.C.3
  • 39
    • 15044366202 scopus 로고
    • The effect of acid stimulation of the duodenum upon experimental hyperglycemia and utilization of glucose
    • Loew, E.R., Gray, J.S. & Ivy, A.C. 1940a. The effect of acid stimulation of the duodenum upon experimental hyperglycemia and utilization of glucose. Am J Physiol 128, 298-308.
    • (1940) Am J Physiol , vol.128 , pp. 298-308
    • Loew, E.R.1    Gray, J.S.2    Ivy, A.C.3
  • 40
    • 0000103499 scopus 로고
    • Is a duodenal hormone involved in carbohydrate metabolism?
    • Loew, E.R., Gray, J.S. & Ivy, A.C. 1940b. Is a duodenal hormone involved in carbohydrate metabolism? Am J Physiol 129, 659-663.
    • (1940) Am J Physiol , vol.129 , pp. 659-663
    • Loew, E.R.1    Gray, J.S.2    Ivy, A.C.3
  • 41
    • 0002294149 scopus 로고
    • New interpretation of oral glucose tolerance
    • McIntyre, N., Holdsworth, C.D. & Turner, D.A. 1964. New interpretation of oral glucose tolerance. Lancet II, 20-21.
    • (1964) Lancet , vol.2 , pp. 20-21
    • Mcintyre, N.1    Holdsworth, C.D.2    Turner, D.A.3
  • 42
    • 0002025725 scopus 로고
    • On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane
    • Moore, B., Edie, E.S. & Abram, J.H. 1906. On the treatment of diabetes mellitus by acid extract of duodenal mucous membrane. Biochem J 1, 28-38.
    • (1906) Biochem J , vol.1 , pp. 28-38
    • Moore, B.1    Edie, E.S.2    Abram, J.H.3
  • 43
    • 0014572556 scopus 로고
    • Effect of the C-terminal tetrapeptide amide of gastrin on insulin secretion in man
    • Ohgawara, H., Mizuno, Y., Tasaka, Y. & Kosaka, K. 1969. Effect of the C-terminal tetrapeptide amide of gastrin on insulin secretion in man. J Clin Endocrinol Metab 29, 1261-1262.
    • (1969) J Clin Endocrinol Metab , vol.29 , pp. 1261-1262
    • Ohgawara, H.1    Mizuno, Y.2    Tasaka, Y.3    Kosaka, K.4
  • 44
    • 0014985305 scopus 로고
    • Effect of gastrin and its C-terminal tetrapeptide on insulin secretion in man
    • Rehfeld, J.F. 1971. Effect of gastrin and its C-terminal tetrapeptide on insulin secretion in man. Acta Endocrinol (Copenh) 66, 169-176.
    • (1971) Acta Endocrinol (Copenh) , vol.66 , pp. 169-176
    • Rehfeld, J.F.1
  • 45
    • 0017154645 scopus 로고
    • Disturbed islet-cell function related to endogenous gastrin release. Studies on insulin secretion and glucose tolerance in pernicious anemia
    • Rehfeld, J.F. 1976. Disturbed islet-cell function related to endogenous gastrin release. Studies on insulin secretion and glucose tolerance in pernicious anemia. J Clin Invest 58, 41-49.
    • (1976) J Clin Invest , vol.58 , pp. 41-49
    • Rehfeld, J.F.1
  • 46
    • 0017899221 scopus 로고
    • Immunochemical studies on cholecystokinin. II. Distribution and molecular heterogeneity in the central nervous system and small intestine of man and hog
    • Rehfeld, J.F. 1978. Immunochemical studies on cholecystokinin. II. Distribution and molecular heterogeneity in the central nervous system and small intestine of man and hog. J Biol Chem 253, 4022-4030.
    • (1978) J Biol Chem , vol.253 , pp. 4022-4030
    • Rehfeld, J.F.1
  • 47
    • 0032583133 scopus 로고    scopus 로고
    • How to measure cholecystokinin in tissue, plasma and cerebrospinal fluid
    • Rehfeld, J.F. 1998a. How to measure cholecystokinin in tissue, plasma and cerebrospinal fluid. Regul Pept 78, 31-39.
    • (1998) Regul Pept , vol.78 , pp. 31-39
    • Rehfeld, J.F.1
  • 48
    • 0031722813 scopus 로고    scopus 로고
    • The new biology of gastrointestinal hormones
    • Rehfeld, J.F. 1998b. The new biology of gastrointestinal hormones. Physiol Rev 78, 1087-1108.
    • (1998) Physiol Rev , vol.78 , pp. 1087-1108
    • Rehfeld, J.F.1
  • 49
    • 0023026263 scopus 로고
    • Characterization of preprocholecystokinin products in the porcine cerebral cortex. Evidence of different processing pathways
    • Rehfeld, J.F. & Hansen, H.F. 1986. Characterization of preprocholecystokinin products in the porcine cerebral cortex. Evidence of different processing pathways. J Biol Chem 261, 5832-5840.
    • (1986) J Biol Chem , vol.261 , pp. 5832-5840
    • Rehfeld, J.F.1    Hansen, H.F.2
  • 50
    • 0028023011 scopus 로고
    • Identification of gastrin component I as gastrin-71. The largest possible bioactive progastrin product
    • Rehfeld, J.F. & Johnsen, A.H. 1994. Identification of gastrin component I as gastrin-71. The largest possible bioactive progastrin product. Eur J Biochem 223, 765-773.
    • (1994) Eur J Biochem , vol.223 , pp. 765-773
    • Rehfeld, J.F.1    Johnsen, A.H.2
  • 51
    • 0015631891 scopus 로고
    • The effect of gastrin on basal- and glucose-stimulated insulin secretion in man
    • Rehfeld, J.F. & Stadil, F. 1973. The effect of gastrin on basal- and glucose-stimulated insulin secretion in man. J Clin Invest 52, 1415-1426.
    • (1973) J Clin Invest , vol.52 , pp. 1415-1426
    • Rehfeld, J.F.1    Stadil, F.2
  • 53
    • 0018139383 scopus 로고
    • The effect of gastrin on basal and aminoacid-stimulated insulin and glucagon secretion in man
    • Rehfeld, J.F., Holst, J.J. & Kuhl, C. 1978. The effect of gastrin on basal and aminoacid-stimulated insulin and glucagon secretion in man. Eur J Clin Invest 8, 5-9.
    • (1978) Eur J Clin Invest , vol.8 , pp. 5-9
    • Rehfeld, J.F.1    Holst, J.J.2    Kuhl, C.3
  • 55
    • 0028816811 scopus 로고
    • Post-poly(Glu) cleavage and degradation modified by O-sulfated tyrosine: a novel post-translational processing mechanism
    • Rehfeld, J.F., Hansen, C.P. & Johnsen, A.H. 1995. Post-poly(Glu) cleavage and degradation modified by O-sulfated tyrosine: a novel post-translational processing mechanism. EMBO J 14, 389-396.
    • (1995) EMBO J , vol.14 , pp. 389-396
    • Rehfeld, J.F.1    Hansen, C.P.2    Johnsen, A.H.3
  • 56
    • 0035145814 scopus 로고    scopus 로고
    • The predominant cholecystokinin in human plasma and intestine is cholecystokinin-33
    • Rehfeld, J.F., Sun, G., Christensen, T. & Hillingso, J.G. 2001. The predominant cholecystokinin in human plasma and intestine is cholecystokinin-33. J Clin Endocrinol Metab 86, 251-258.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 251-258
    • Rehfeld, J.F.1    Sun, G.2    Christensen, T.3    Hillingso, J.G.4
  • 58
    • 41549129970 scopus 로고    scopus 로고
    • The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6
    • Rehfeld, J.F., Bundgaard, J.R., Hannibal, J., Zhu, X., Norrbom, C., Steiner, D.F. & Friis-Hansen, L. 2008. The cell-specific pattern of cholecystokinin peptides in endocrine cells versus neurons is governed by the expression of prohormone convertases 1/3, 2, and 5/6. Endocrinology 149, 1600-1608.
    • (2008) Endocrinology , vol.149 , pp. 1600-1608
    • Rehfeld, J.F.1    Bundgaard, J.R.2    Hannibal, J.3    Zhu, X.4    Norrbom, C.5    Steiner, D.F.6    Friis-Hansen, L.7
  • 59
    • 0042854927 scopus 로고    scopus 로고
    • Peptide receptors as molecular targets for cancer diagnosis and therapy
    • Reubi, J.C. 2003. Peptide receptors as molecular targets for cancer diagnosis and therapy. Endocr Rev 24, 389-427.
    • (2003) Endocr Rev , vol.24 , pp. 389-427
    • Reubi, J.C.1
  • 60
    • 0030902066 scopus 로고    scopus 로고
    • Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors
    • Reubi, J.C., Schaer, J.C. & Waser, B. 1997. Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors. Cancer Res 57, 1377-1386.
    • (1997) Cancer Res , vol.57 , pp. 1377-1386
    • Reubi, J.C.1    Schaer, J.C.2    Waser, B.3
  • 62
    • 1542284736 scopus 로고    scopus 로고
    • Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan
    • Rooman, I. & Bouwens, L. 2004. Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan. Diabetologia 47, 259-265.
    • (2004) Diabetologia , vol.47 , pp. 259-265
    • Rooman, I.1    Bouwens, L.2
  • 63
    • 0036310118 scopus 로고    scopus 로고
    • Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue
    • Rooman, I., Lardon, J. & Bouwens, L. 2002. Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue. Diabetes 51, 686-690.
    • (2002) Diabetes , vol.51 , pp. 686-690
    • Rooman, I.1    Lardon, J.2    Bouwens, L.3
  • 66
    • 50249234375 scopus 로고
    • The Croonian Lectures on the chemical correlation of the functions of the body
    • Starling, E.H. 1905. The Croonian Lectures on the chemical correlation of the functions of the body. Lancet 2, 339-583.
    • (1905) Lancet , vol.2 , pp. 339-583
    • Starling, E.H.1
  • 67
    • 24144446405 scopus 로고    scopus 로고
    • Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice
    • Suarez-Pinzon, W.L., Yan, Y., Power, R., Brand, S.J. & Rabinovitch, A. 2005. Combination therapy with epidermal growth factor and gastrin increases beta-cell mass and reverses hyperglycemia in diabetic NOD mice. Diabetes 54, 2596-2601.
    • (2005) Diabetes , vol.54 , pp. 2596-2601
    • Suarez-Pinzon, W.L.1    Yan, Y.2    Power, R.3    Brand, S.J.4    Rabinovitch, A.5
  • 68
    • 58149357117 scopus 로고    scopus 로고
    • Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice
    • Suarez-Pinzon, W.L., Power, R.F., Yan, Y., Wasserfall, C., Atkinson, M. & Rabinovitch, A. 2008. Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice. Diabetes 57, 3281-3288.
    • (2008) Diabetes , vol.57 , pp. 3281-3288
    • Suarez-Pinzon, W.L.1    Power, R.F.2    Yan, Y.3    Wasserfall, C.4    Atkinson, M.5    Rabinovitch, A.6
  • 69
    • 0027194337 scopus 로고
    • Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells
    • Wang, T.C., Bonner-Weir, S., Oates, P.S., Chulak, M., Simon, B., Merlino, G.T., Schmidt, E.V. & Brand, S.J. 1993. Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J Clin Invest 92, 1349-1356.
    • (1993) J Clin Invest , vol.92 , pp. 1349-1356
    • Wang, T.C.1    Bonner-Weir, S.2    Oates, P.S.3    Chulak, M.4    Simon, B.5    Merlino, G.T.6    Schmidt, E.V.7    Brand, S.J.8
  • 70
    • 0030747583 scopus 로고    scopus 로고
    • Expression of gastrin and transforming growth factor-alpha during duct to islet cell differentiation in the pancreas of duct-ligated adult rats
    • Wang, R.N., Rehfeld, J.F., Nielsen, F.C. & Kloppel, G. 1997. Expression of gastrin and transforming growth factor-alpha during duct to islet cell differentiation in the pancreas of duct-ligated adult rats. Diabetologia 40, 887-893.
    • (1997) Diabetologia , vol.40 , pp. 887-893
    • Wang, R.N.1    Rehfeld, J.F.2    Nielsen, F.C.3    Kloppel, G.4
  • 71
    • 0028845124 scopus 로고
    • Cholecystokinin receptors
    • Wank, S.A. 1995. Cholecystokinin receptors. Am J Physiol 269, G628-G646.
    • (1995) Am J Physiol , vol.269
    • Wank, S.A.1
  • 72
    • 0026559686 scopus 로고
    • Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas
    • Wank, S.A., Harkins, R., Jensen, R.T., Shapira, H., de, W.A. & Slattery, T. 1992. Purification, molecular cloning, and functional expression of the cholecystokinin receptor from rat pancreas. Proc Natl Acad Sci USA 89, 3125-3129.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3125-3129
    • Wank, S.A.1    Harkins, R.2    Jensen, R.T.3    Shapira, H.4    de, W.A.5    Slattery, T.6


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