Temperature-modulated photodynamic therapy for the treatment of actinic keratosis on the extremities: A pilot study

Dermatologic Surgery

Volumn 40, Issue 10, 2014, Pages 1094-1102

  Willey, Andrea ^a,b   Anderson, R Rox ^c,d   Sakamoto, Fernanda H ^c,d  

^a Surgical and Aesthetic Dermatology Sacramento   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; PORPHYRIN; PHOTOSENSITIZING AGENT;

ACTINIC KERATOSIS; AGED; ARTICLE; BLOOD VESSEL TONE; BURN; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; ENVIRONMENTAL TEMPERATURE; ERYTHEMA; FEMALE; GLOBAL CHANGE; HEATING; HUMAN; HUMAN TISSUE; HUMIDITY; INCUBATION TIME; MALE; PATIENT SAFETY; PATIENT SATISFACTION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ROOM TEMPERATURE; SKIN TEMPERATURE; TEMPERATURE DEPENDENCE; THERMOMETER; BLISTER; CLINICAL PROTOCOL; LIMB; METHODOLOGY; MIDDLE AGED; PAIN; PHOTOCHEMOTHERAPY; PILOT STUDY; TEMPERATURE; TREATMENT OUTCOME; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AMINOLEVULINIC ACID; BLISTER; CLINICAL PROTOCOLS; ERYTHEMA; EXTREMITIES; FEMALE; HUMANS; KERATOSIS, ACTINIC; MALE; MIDDLE AGED; PAIN; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PILOT PROJECTS; SKIN TEMPERATURE; TEMPERATURE; TREATMENT OUTCOME;

EID: 84909581915     PISSN: 10760512     EISSN: 15244725     Source Type: Journal    
DOI: 10.1097/01.DSS.0000452662.69539.57     Document Type: Article

References (53)

1. Fink-Puches R, Hofer A, Smolle J, Kerl H, et al. Primary clinical response and long-term follow-up of solar keratoses treated with topically applied 5-aminolevulinic acid and irradiation by different wave bands of light. J Photochem Photobiol B 1997;41:145-51.
2. Jeffes EW, McCullough JL, Weinstein GD, Kaplan R, et al. Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light. J Am Acad Dermatol 2001;45:96-104.
3. Piacquadio DJ, Chen DM, Farber HF, Fowler JF Jr, et al. Photodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials. Arch Dermatol 2004; 140:41-6.
4. Tschen EH, Wong DS, Pariser DM, Dunlap FE, et al; Phase IV ALA-PDT Actinic Keratosis Study Group. Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up. Br J Dermatol 2006;155:1262-9.
5. Moloney FJ, Collins P. Randomized, double-blind, prospective study to compare topical 5-aminolaevulinic acid methylester with topical 5-aminolaevulinic acid photodynamic therapy for extensive scalp actinic keratosis. Br J Dermatol 2007;157:87-91.
6. Piaserico S, Belloni Fortina A, Rigotti P, Rossi B, et al. Topical photodynamic therapy of actinic keratosis in renal transplant recipients. Transplant Proc 2007;39:1847-50.
7. Stritt A, Merk HF, Braathen LR, Felbert V. Photodynamic therapy in the treatment of actinic keratosis. Photochem Photobiol 2008;84:388-98.
8. Smith S, Piacquadio D, Morhenn V, Atkin D, et al. Short incubation PDT versus 5-FU in treating actinic keratoses. J Drugs Dermatol 2003;2: 629-35.
9. Sotiriou E, Apalla Z, Maliamani F, Zaparas N, et al. Intraindividual, right-left comparison of topical 5-aminolevulinic acid photodynamic therapy vs. 5% imiquimod cream for actinic keratoses on the upper extremities. J Eur Acad Dermatol Venereol 2009;23:1061-5.
10. Taub AF, Garretson CB. A randomized, blinded, bilateral intraindividual vehicle-controlled trial of the use of photodynamic therapy with 5-aminolevulinic acid and blue light for the treatment of actinic keratoses of the upper extremities. J Drugs Dermatol 2011;10: 1049-56.
11. Apalla Z, Sotiriou E, Chovarda E, Lefaki I, et al. Skin Cancer: preventative photodynamic therapy in patients with face and scalp cancerization. A randomized placebo controlled study. Br J Dermatol 2010;162:171-5.
12. Goldberg LH, Landau JM, Moody MN, Marquez D, et al. Evaluation of the chemopreventative effects of ALA PDT in patients with multiple actinic keratoses and a history of skin cancer. J Drugs Dermatol 2012;11:593-7.
13. Morton CA, McKenna KE, Rhodes LE. Guidelines for topical photodynamic therapy: update. Br J Dermatol 2008;159:1245-66.
14. Braathen LR, Szeimies RM, Basset-Seguin N, Bissonnette R, et al; International Society for Photodynamic Therapy in Dermatology. Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005. J Am Acad Dermatol 2007;56:125-43.
15. Wulf HC, Pavel S, Stender I, Bakker-Wensveen CA. Topical photodynamic therapy for prevention of new skin lesions in renal transplant recipients. Acta Derm Venereol 2006;86:25-8.
16. Wennberg AM, Stenquist B, Stockfleth E, Keohane S, et al. Photodynamic therapy with methyl aminolevulinate for prevention of new skin lesions in transplant recipients: a randomized study. Transplantation 2008;86:423-9.
17. Willey A, Mehta S, Lee PK. Reduction in the incidence of squamous cell carcinoma in solid organ transplant recipients treated with cyclic photodynamic therapy. Dermatol Surg 2010;36:652-8.
18. Braathen LR, Morton CA, Basset-Seguin N, Bissonnette R, et al. Photodynamic therapy for skin field cancerization: an international consensus. International Society for Photodynamic Therapy in Dermatology. J Eur Acad Dermatol Venereol 2012;26:1063-6.
19. Zhao B, He YY. Recent advances in the prevention and treatment of skin cancer using photodynamic therapy. Expert Rev Anticancer Ther 2010;10:1797-809.
20. Hadley J, Tristani-Firouzi P, Hull C, Florell S, et al. Results of an investigator-initiated single-blind split-face comparison of photodynamic therapy and 5% imiquimod cream for the treatment of actinic keratoses. Dermatol Surg 2012;38:722-7.
21. Tyrrell JS, Morton C, Campbell SM, Curnow A. Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites. Br J Dermatol 2011;164:1362-8.
22. Lesar A, Ferguson J, Moseley H. An investigation of the fluorescence induced by topical application of 5-aminolaevulinic acid and methyl aminolaevulinate at different body sites on normal human skin. Photodiagnosis Photodyn Ther 2011;8:97-103.
23. Juzenas P, Sørensen R, Iani V, Moan J. Uptake of topically applied 5-aminolevulinic acid and production of protoporphyrin IX in normal mouse skin: dependence on skin temperature. Photochem Photobiol 1999;69:478-81.
24. Moan J, Berg K, Gadmarl OB, Ianil V, et al. The temperature dependence of protoporphyrin IX production in cells and tissues. Photochem and Photobiol 1999;70:669-73.
25. Juzeniene A, Juzenas P, Kaalhus O, Iani V, et al. Temperature effect on accumulation of protoporphyrin IX after topical application of 5-aminolevulinic acid and its methylester and hexylester derivatives in normal mouse skin. Photochem Photobiol 2002;76:452-6.
26. Ishida N,Watanabe D,Mizutani K, AkimotoM, et al. Heating increases protoporphyrin IX production in normal skin after delivery of 5-aminolevulinic acid by iontophoresis. Photodermatol Photoimmunol Photomed 2009;25:333-4.
27. Van den Akker JT, Boot K, Vernon DI, Brown SB, et al. Effect of elevating the skin temperature during topical ALA application on in vitro ALA penetration through mouse skin and in vivo PpIX production in human skin. Photochem Photobiol Sci 2004;3:263-7.
28. Yang J, Chen AC, Wu Q, Jiang S, et al. The influence of temperature on 5-aminole-vulinic acid-based photodynamic reaction in keratinocytes in vitro. Photodermatol Photoimmunol Photomed 2010;26:83-8.
29. Flanagin A. Who wrote the declaration of Helsinki? JAMA 1997;277: 925-6.
30. WMA's Declaration of Helsinki serves as a guide to physicians. JAMA 1964;189:33-4.
31. Rowell LB. Reflex control of the cutaneous vasculature. J Invest Dermatol 1977;69:154-66.
32. Johnson JM, Kellogg DL Jr. Local thermal control of the human cutaneous circulation. J Appl Physiol 2010;109:1229-38.
33. Mackowiak PA, Wasserman SS, Levine MM. A critical appraisal of 98.6 degrees F, the upper limit of the normal body temperature, and other legacies of Carl Reinhold AugustWunderlich. JAMA 1992;268:1578-80.
34. Petrofsky J, Alshahmmari F, Yim JE, Hamdan A, et al. The interrealtionship between locally applied heat, ageing and skin blood flow on heat transfer into and fromthe skin. J Med Eng Technol 2011;35:262-74.
35. Griffith JM, Hamilton A, Long G, Mujezinovic A, et al. Human skin temperature response to absorbed thermal power. SPIE Medical Imaging Symposium: Newport Beach, 1997; pp. 129-34.
36. Hertzman AB. Some relations between skin temperature and blood flow. Am J Phys Med 1953;32:233-51.
37. Hertzman AB. Vasomotor regulation of cutaneous circulation. Physiol Rev 1959;39:280-306.
38. Hertzman AB, Randall WC. Regional differences in the basal and maximal rates of blood flow in the skin. J Appl Physiol 1948;1:234-41.
39. Standard Number 1910.1000 OSHA Policy on Indoor Air Quality: Office Temperature/Humidity and Environmental Tobacco Smoke. Available from: www.osha.gov/pls/oshaweb/owadisp.show-document? p-table=INTERPRETATIONS&;p-id=24602. Accessed on December 8, 2013.
40. CharkoudianN. Skin blood flow in adult human thermoregulation: how it works, when it does not, and why. Mayo Clin Proc 2003;78:603-12.
41. Moritz AR, Henriques FC. Studies of Thermal Injury: II. The relative importance of time and surface temperature in the causation of cutaneous burns. Am J Pathol 1947;23:695-720.
42. Greenhalgh DG, Lawless MB, Chew BB, Crone WA, et al. Temperature threshold for burn injury: an oximeter safety study. J Burn Care Rehabil 2004;25:411-5.
43. Siekmann H. Recommended maximum temperatures for touchable surfaces. Appl Ergon 1990;21:69-73.
44. Diller KR. Analysis of burns caused by long-term exposure to a heating pad. J Burn Care Rehabil 1991;12:214-7.
45. Suzuki T, Hirayama T, Aihara K, Hirohata Y. Experimental studies of moderate temperature burns. Burns 1991;17:443-51.
46. Blatteis CM. Age-dependent changes in temperature regulation-a mini review. Gerontology 2012;58:289-95.
47. Bill TJ, Edlich RF, Himel HN. Electric heating pad burns. J Emerg Med 1994;12:819-24.
48. Gosselin TK. Thermal wounds following heating pad use. Clin J Oncol Nurs 2003;7:87-8.
49. Ozgenel Ege GY, Ozcan M. Heating-pad burn as a complication of abdominoplasty. Br J Plast Surg 2003;56:52-3.
50. Stevenson TR, Hammond DC, Keip D, Argenta LC. Heating pad burns in anesthetic skin. Ann Plast Surg 1985;15:73-5.
51. Katcher ML, Shapiro MM. Lower extremity burns related to sensory loss in diabetes mellitus. J Fam Pract 1987;24:149-51.
52. Kistemaker JA, Den Hartog EA, Daanen HA. Reliability of an infrared forehead skin thermometer for core temperature measurements. J Med Eng Technol 2006;30:252-61.
53. Burnham RS, McKinley RS, Vincent DD. Three types of skin-surface thermometers: a comparison of reliability, validity, and responsiveness. Am J Phys Med Rehabil 2006;85:553-8.