Whole-cell biotransformation with recombinant cytochrome P450 for the selective oxidation of Grundmann's ketone

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 20, 2014, Pages 5586-5592

  Hernández Martín, Alba ^a,b   Von Bühler, Clemens J ^a   Tieves, Florian ^a   Fernández, Susana ^b   Ferrero, Miguel ^b   Urlacher, Vlada B ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF OVIEDO   (Spain)

Author keywords

Cytochrome P450; Grundmann's ketone; Hydroxylation; Vitamin D3; Whole cell biocatalysis

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 102A2; CYTOCHROME P450 105A1; CYTOCHROME P450 BM3; GRUNDMANN KETONE; KETONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

ARTICLE; BIOTRANSFORMATION; ENZYME ACTIVITY; ESCHERICHIA COLI; HETEROLOGOUS EXPRESSION; IN VITRO STUDY; OXIDATION; BACILLUS SUBTILIS; BIOCATALYSIS; CHEMISTRY; CONFORMATION; CYTOLOGY; ENZYMOLOGY; METABOLISM; OXIDATION REDUCTION REACTION; PSEUDOMONAS PUTIDA;

BACILLUS SUBTILIS; BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; KETONES; MOLECULAR CONFORMATION; OXIDATION-REDUCTION; PSEUDOMONAS PUTIDA; RECOMBINANT PROTEINS;

EID: 84908554586     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.06.005     Document Type: Article

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