-
1
-
-
60549109895
-
Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease
-
Azeredo da Silveira S., Schneider B.L., Cifuentes-Diaz C., Sage D., Abbas-Terki T., Iwatsubo T., Unser M., Aebischer P. Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease. Hum. Mol. Genet. 2009, 18:872-887.
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 872-887
-
-
Azeredo da Silveira, S.1
Schneider, B.L.2
Cifuentes-Diaz, C.3
Sage, D.4
Abbas-Terki, T.5
Iwatsubo, T.6
Unser, M.7
Aebischer, P.8
-
2
-
-
84857834456
-
Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease
-
Coune P.G., Bensadoun J.C., Aebischer P., Schneider B.L. Rab1A over-expression prevents Golgi apparatus fragmentation and partially corrects motor deficits in an alpha-synuclein based rat model of Parkinson's disease. J. Parkinsons Dis. 2011, 1:373-387.
-
(2011)
J. Parkinsons Dis.
, vol.1
, pp. 373-387
-
-
Coune, P.G.1
Bensadoun, J.C.2
Aebischer, P.3
Schneider, B.L.4
-
3
-
-
84867741659
-
Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants
-
Covy J.P., Waxman E.A., Giasson B.I. Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. J. Neurosci. Res. 2012, 90:2306-2316.
-
(2012)
J. Neurosci. Res.
, vol.90
, pp. 2306-2316
-
-
Covy, J.P.1
Waxman, E.A.2
Giasson, B.I.3
-
4
-
-
84861162180
-
Neurodegenerative phenotypes in an A53T alpha-synuclein transgenic mouse model are independent of LRRK2
-
Daher J.P., Pletnikova O., Biskup S., Musso A., Gellhaar S., Galter D., Troncoso J.C., Lee M.K., Dawson T.M., Dawson V.L., et al. Neurodegenerative phenotypes in an A53T alpha-synuclein transgenic mouse model are independent of LRRK2. Hum. Mol. Genet. 2012, 21:2420-2431.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 2420-2431
-
-
Daher, J.P.1
Pletnikova, O.2
Biskup, S.3
Musso, A.4
Gellhaar, S.5
Galter, D.6
Troncoso, J.C.7
Lee, M.K.8
Dawson, T.M.9
Dawson, V.L.10
-
5
-
-
80051985178
-
GDNF fails to exert neuroprotection in a rat alpha-synuclein model of Parkinson's disease
-
Decressac M., Ulusoy A., Mattsson B., Georgievska B., Romero-Ramos M., Kirik D., Bjorklund A. GDNF fails to exert neuroprotection in a rat alpha-synuclein model of Parkinson's disease. Brain 2011, 134:2302-2311.
-
(2011)
Brain
, vol.134
, pp. 2302-2311
-
-
Decressac, M.1
Ulusoy, A.2
Mattsson, B.3
Georgievska, B.4
Romero-Ramos, M.5
Kirik, D.6
Bjorklund, A.7
-
6
-
-
0033977265
-
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease
-
Deglon N., Tseng J.L., Bensadoun J.C., Zurn A.D., Arsenijevic Y., Pereira de Almeida L., Zufferey R., Trono D., Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene Ther. 2000, 11:179-190.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 179-190
-
-
Deglon, N.1
Tseng, J.L.2
Bensadoun, J.C.3
Zurn, A.D.4
Arsenijevic, Y.5
Pereira de Almeida, L.6
Zufferey, R.7
Trono, D.8
Aebischer, P.9
-
7
-
-
84862189804
-
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration
-
Dehay B., Ramirez A., Martinez-Vicente M., Perier C., Canron M.H., Doudnikoff E., Vital A., Vila M., Klein C., Bezard E. Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration. Proc. Natl. Acad. Sci. U. S. A. 2012, 109:9611-9616.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 9611-9616
-
-
Dehay, B.1
Ramirez, A.2
Martinez-Vicente, M.3
Perier, C.4
Canron, M.H.5
Doudnikoff, E.6
Vital, A.7
Vila, M.8
Klein, C.9
Bezard, E.10
-
8
-
-
34248182509
-
ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease
-
Di Fonzo A., Chien H.F., Socal M., Giraudo S., Tassorelli C., Iliceto G., Fabbrini G., Marconi R., Fincati E., Abbruzzese G., et al. ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease. Neurology 2007, 68:1557-1562.
-
(2007)
Neurology
, vol.68
, pp. 1557-1562
-
-
Di Fonzo, A.1
Chien, H.F.2
Socal, M.3
Giraudo, S.4
Tassorelli, C.5
Iliceto, G.6
Fabbrini, G.7
Marconi, R.8
Fincati, E.9
Abbruzzese, G.10
-
9
-
-
67349270248
-
Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease
-
Dusonchet J., Bensadoun J.C., Schneider B.L., Aebischer P. Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease. Neurobiol. Dis. 2009, 35:32-41.
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 32-41
-
-
Dusonchet, J.1
Bensadoun, J.C.2
Schneider, B.L.3
Aebischer, P.4
-
10
-
-
69149089036
-
Molecular pathogenesis of Parkinson disease: insights from genetic studies
-
Gasser T. Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert. Rev. Mol. Med. 2009, 11:e22.
-
(2009)
Expert. Rev. Mol. Med.
, vol.11
, pp. e22
-
-
Gasser, T.1
-
12
-
-
84862646368
-
Nigrostriatal overabundance of alpha-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity
-
Gaugler M.N., Genc O., Bobela W., Mohanna S., Ardah M.T., El-Agnaf O.M., Cantoni M., Bensadoun J.C., Schneggenburger R., Knott G.W., et al. Nigrostriatal overabundance of alpha-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity. Acta Neuropathol. 2012, 123:653-669.
-
(2012)
Acta Neuropathol.
, vol.123
, pp. 653-669
-
-
Gaugler, M.N.1
Genc, O.2
Bobela, W.3
Mohanna, S.4
Ardah, M.T.5
El-Agnaf, O.M.6
Cantoni, M.7
Bensadoun, J.C.8
Schneggenburger, R.9
Knott, G.W.10
-
13
-
-
61349147706
-
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
-
Gitler A.D., Chesi A., Geddie M.L., Strathearn K.E., Hamamichi S., Hill K.J., Caldwell K.A., Caldwell G.A., Cooper A.A., Rochet J.C., et al. Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity. Nat. Genet. 2009, 41:308-315.
-
(2009)
Nat. Genet.
, vol.41
, pp. 308-315
-
-
Gitler, A.D.1
Chesi, A.2
Geddie, M.L.3
Strathearn, K.E.4
Hamamichi, S.5
Hill, K.J.6
Caldwell, K.A.7
Caldwell, G.A.8
Cooper, A.A.9
Rochet, J.C.10
-
14
-
-
84861883543
-
ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome
-
Grunewald A., Arns B., Seibler P., Rakovic A., Munchau A., Ramirez A., Sue C.M., Klein C. ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome. Neurobiol. Aging 2012, 33:31.
-
(2012)
Neurobiol. Aging
, vol.33
, pp. 31
-
-
Grunewald, A.1
Arns, B.2
Seibler, P.3
Rakovic, A.4
Munchau, A.5
Ramirez, A.6
Sue, C.M.7
Klein, C.8
-
15
-
-
84856578855
-
ATP13A2 regulates mitochondrial bioenergetics through macroautophagy
-
Gusdon A.M., Zhu J., Van Houten B., Chu C.T. ATP13A2 regulates mitochondrial bioenergetics through macroautophagy. Neurobiol. Dis. 2012, 45:962-972.
-
(2012)
Neurobiol. Dis.
, vol.45
, pp. 962-972
-
-
Gusdon, A.M.1
Zhu, J.2
Van Houten, B.3
Chu, C.T.4
-
16
-
-
55849122639
-
Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
-
Henchcliffe C., Beal M.F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol. 2008, 4:600-609.
-
(2008)
Nat. Clin. Pract. Neurol.
, vol.4
, pp. 600-609
-
-
Henchcliffe, C.1
Beal, M.F.2
-
17
-
-
84908501382
-
Parkinson's Disease linked human PARK9 / ATP13A2 maintains zinc homeostasis and promotes alphaSynuclein externalisation via exosomes
-
Kong S.M., Chan B.K., Park J.S., Hill K.J., Aitken J.B., Cottle L., Farghaian H., Cole A.R., Lay P.A., Sue C.M., et al. Parkinson's Disease linked human PARK9 / ATP13A2 maintains zinc homeostasis and promotes alphaSynuclein externalisation via exosomes. Hum. Mol. Genet. 2014, 6:6.
-
(2014)
Hum. Mol. Genet.
, vol.6
, pp. 6
-
-
Kong, S.M.1
Chan, B.K.2
Park, J.S.3
Hill, K.J.4
Aitken, J.B.5
Cottle, L.6
Farghaian, H.7
Cole, A.R.8
Lay, P.A.9
Sue, C.M.10
-
18
-
-
0032497504
-
Parkinson's disease. First of two parts
-
Lang A.E., Lozano A.M. Parkinson's disease. First of two parts. N. Engl. J. Med. 1998, 339:1044-1053.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1044-1053
-
-
Lang, A.E.1
Lozano, A.M.2
-
19
-
-
0032531924
-
Parkinson's disease. Second of two parts
-
Lang A.E., Lozano A.M. Parkinson's disease. Second of two parts. N. Engl. J. Med. 1998, 339:1130-1143.
-
(1998)
N. Engl. J. Med.
, vol.339
, pp. 1130-1143
-
-
Lang, A.E.1
Lozano, A.M.2
-
20
-
-
84865535547
-
Use of viral vectors to create animal models for Parkinson's disease
-
Low K., Aebischer P. Use of viral vectors to create animal models for Parkinson's disease. Neurobiol. Dis. 2012, 48:189-201.
-
(2012)
Neurobiol. Dis.
, vol.48
, pp. 189-201
-
-
Low, K.1
Aebischer, P.2
-
21
-
-
0037255184
-
Dual vectors expressing murine factor VIII result in sustained correction of hemophilia A mice
-
Mah C., Sarkar R., Zolotukhin I., Schleissing M., Xiao X., Kazazian H.H., Byrne B.J. Dual vectors expressing murine factor VIII result in sustained correction of hemophilia A mice. Hum. Gene Ther. 2003, 14:143-152.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 143-152
-
-
Mah, C.1
Sarkar, R.2
Zolotukhin, I.3
Schleissing, M.4
Xiao, X.5
Kazazian, H.H.6
Byrne, B.J.7
-
22
-
-
84876479782
-
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons
-
Matsui H., Sato F., Sato S., Koike M., Taruno Y., Saiki S., Funayama M., Ito H., Taniguchi Y., Uemura N., et al. ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons. FEBS Lett. 2013, 587:1316-1325.
-
(2013)
FEBS Lett.
, vol.587
, pp. 1316-1325
-
-
Matsui, H.1
Sato, F.2
Sato, S.3
Koike, M.4
Taruno, Y.5
Saiki, S.6
Funayama, M.7
Ito, H.8
Taniguchi, Y.9
Uemura, N.10
-
23
-
-
20744435383
-
Molecular pathophysiology of Parkinson's disease
-
Moore D.J., West A.B., Dawson V.L., Dawson T.M. Molecular pathophysiology of Parkinson's disease. Annu. Rev. Neurosci. 2005, 28:57-87.
-
(2005)
Annu. Rev. Neurosci.
, vol.28
, pp. 57-87
-
-
Moore, D.J.1
West, A.B.2
Dawson, V.L.3
Dawson, T.M.4
-
24
-
-
0028298816
-
Pallido-pyramidal degeneration, supranuclear upgaze paresis and dementia: Kufor-Rakeb syndrome
-
Najim al-Din A.S., Wriekat A., Mubaidin A., Dasouki M., Hiari M. Pallido-pyramidal degeneration, supranuclear upgaze paresis and dementia: Kufor-Rakeb syndrome. Acta Neurol. Scand. 1994, 89:347-352.
-
(1994)
Acta Neurol. Scand.
, vol.89
, pp. 347-352
-
-
Najim al-Din, A.S.1
Wriekat, A.2
Mubaidin, A.3
Dasouki, M.4
Hiari, M.5
-
25
-
-
42049103656
-
PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype
-
Ning Y.P., Kanai K., Tomiyama H., Li Y., Funayama M., Yoshino H., Sato S., Asahina M., Kuwabara S., Takeda A., et al. PARK9-linked parkinsonism in eastern Asia: mutation detection in ATP13A2 and clinical phenotype. Neurology 2008, 70:1491-1493.
-
(2008)
Neurology
, vol.70
, pp. 1491-1493
-
-
Ning, Y.P.1
Kanai, K.2
Tomiyama, H.3
Li, Y.4
Funayama, M.5
Yoshino, H.6
Sato, S.7
Asahina, M.8
Kuwabara, S.9
Takeda, A.10
-
26
-
-
84885363886
-
Polo-like kinase 2 regulates selective autophagic alpha-synuclein clearance and suppresses its toxicity in vivo
-
Oueslati A., Schneider B.L., Aebischer P., Lashuel H.A. Polo-like kinase 2 regulates selective autophagic alpha-synuclein clearance and suppresses its toxicity in vivo. Proc. Natl. Acad. Sci. U. S. A. 2013, 110:27.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 27
-
-
Oueslati, A.1
Schneider, B.L.2
Aebischer, P.3
Lashuel, H.A.4
-
28
-
-
79960836347
-
Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism
-
Park J.S., Mehta P., Cooper A.A., Veivers D., Heimbach A., Stiller B., Kubisch C., Fung V.S., Krainc D., Mackay-Sim A., et al. Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism. Hum. Mutat. 2011, 32:956-964.
-
(2011)
Hum. Mutat.
, vol.32
, pp. 956-964
-
-
Park, J.S.1
Mehta, P.2
Cooper, A.A.3
Veivers, D.4
Heimbach, A.5
Stiller, B.6
Kubisch, C.7
Fung, V.S.8
Krainc, D.9
Mackay-Sim, A.10
-
29
-
-
84899903061
-
Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction
-
Park J.S., Koentjoro B., Veivers D., Mackay-Sim A., Sue C.M. Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction. Hum. Mol. Genet. 2014, 15:15.
-
(2014)
Hum. Mol. Genet.
, vol.15
, pp. 15
-
-
Park, J.S.1
Koentjoro, B.2
Veivers, D.3
Mackay-Sim, A.4
Sue, C.M.5
-
30
-
-
84863091947
-
Common pathogenic effects of missense mutations in the P-type ATPase ATP13A2 (PARK9) associated with early-onset parkinsonism
-
Podhajska A., Musso A., Trancikova A., Stafa K., Moser R., Sonnay S., Glauser L., Moore D.J. Common pathogenic effects of missense mutations in the P-type ATPase ATP13A2 (PARK9) associated with early-onset parkinsonism. PLoS One 2012, 7:29.
-
(2012)
PLoS One
, vol.7
, pp. 29
-
-
Podhajska, A.1
Musso, A.2
Trancikova, A.3
Stafa, K.4
Moser, R.5
Sonnay, S.6
Glauser, L.7
Moore, D.J.8
-
31
-
-
33749133430
-
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase
-
Ramirez A., Heimbach A., Grundemann J., Stiller B., Hampshire D., Cid L.P., Goebel I., Mubaidin A.F., Wriekat A.L., Roeper J., et al. Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase. Nat. Genet. 2006, 38:1184-1191.
-
(2006)
Nat. Genet.
, vol.38
, pp. 1184-1191
-
-
Ramirez, A.1
Heimbach, A.2
Grundemann, J.3
Stiller, B.4
Hampshire, D.5
Cid, L.P.6
Goebel, I.7
Mubaidin, A.F.8
Wriekat, A.L.9
Roeper, J.10
-
32
-
-
79953758383
-
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
-
Ramonet D., Daher J.P., Lin B.M., Stafa K., Kim J., Banerjee R., Westerlund M., Pletnikova O., Glauser L., Yang L., et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS One 2011, 6:e18568.
-
(2011)
PLoS One
, vol.6
, pp. e18568
-
-
Ramonet, D.1
Daher, J.P.2
Lin, B.M.3
Stafa, K.4
Kim, J.5
Banerjee, R.6
Westerlund, M.7
Pletnikova, O.8
Glauser, L.9
Yang, L.10
-
33
-
-
84859246513
-
PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity
-
Ramonet D., Podhajska A., Stafa K., Sonnay S., Trancikova A., Tsika E., Pletnikova O., Troncoso J.C., Glauser L., Moore D.J. PARK9-associated ATP13A2 localizes to intracellular acidic vesicles and regulates cation homeostasis and neuronal integrity. Hum. Mol. Genet. 2012, 21:1725-1743.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 1725-1743
-
-
Ramonet, D.1
Podhajska, A.2
Stafa, K.3
Sonnay, S.4
Trancikova, A.5
Tsika, E.6
Pletnikova, O.7
Troncoso, J.C.8
Glauser, L.9
Moore, D.J.10
-
34
-
-
79951557128
-
Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variability
-
Santoro L., Breedveld G.J., Manganelli F., Iodice R., Pisciotta C., Nolano M., Punzo F., Quarantelli M., Pappata S., Di Fonzo A., et al. Novel ATP13A2 (PARK9) homozygous mutation in a family with marked phenotype variability. Neurogenetics 2011, 12:33-39.
-
(2011)
Neurogenetics
, vol.12
, pp. 33-39
-
-
Santoro, L.1
Breedveld, G.J.2
Manganelli, F.3
Iodice, R.4
Pisciotta, C.5
Nolano, M.6
Punzo, F.7
Quarantelli, M.8
Pappata, S.9
Di Fonzo, A.10
-
35
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
Satake W., Nakabayashi Y., Mizuta I., Hirota Y., Ito C., Kubo M., Kawaguchi T., Tsunoda T., Watanabe M., Takeda A., et al. Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat. Genet. 2009, 41:1303-1307.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
Kubo, M.6
Kawaguchi, T.7
Tsunoda, T.8
Watanabe, M.9
Takeda, A.10
-
36
-
-
84908512883
-
Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease
-
Schlaudraff F., Grundemann J., Fauler M., Dragicevic E., Hardy J., Liss B. Orchestrated increase of dopamine and PARK mRNAs but not miR-133b in dopamine neurons in Parkinson's disease. Neurobiol. Aging 2014, 22:016.
-
(2014)
Neurobiol. Aging
, vol.22
, pp. 016
-
-
Schlaudraff, F.1
Grundemann, J.2
Fauler, M.3
Dragicevic, E.4
Hardy, J.5
Liss, B.6
-
38
-
-
84877010484
-
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited alpha-synuclein accumulation and age-dependent sensorimotor deficits
-
Schultheis P.J., Fleming S.M., Clippinger A.K., Lewis J., Tsunemi T., Giasson B., Dickson D.W., Mazzulli J.R., Bardgett M.E., Haik K.L., et al. Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited alpha-synuclein accumulation and age-dependent sensorimotor deficits. Hum. Mol. Genet. 2013, 22:2067-2082.
-
(2013)
Hum. Mol. Genet.
, vol.22
, pp. 2067-2082
-
-
Schultheis, P.J.1
Fleming, S.M.2
Clippinger, A.K.3
Lewis, J.4
Tsunemi, T.5
Giasson, B.6
Dickson, D.W.7
Mazzulli, J.R.8
Bardgett, M.E.9
Haik, K.L.10
-
39
-
-
79952303794
-
PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease
-
Shin J.H., Ko H.S., Kang H., Lee Y., Lee Y.I., Pletinkova O., Troconso J.C., Dawson V.L., Dawson T.M. PARIS (ZNF746) repression of PGC-1alpha contributes to neurodegeneration in Parkinson's disease. Cell 2011, 144:689-702.
-
(2011)
Cell
, vol.144
, pp. 689-702
-
-
Shin, J.H.1
Ko, H.S.2
Kang, H.3
Lee, Y.4
Lee, Y.I.5
Pletinkova, O.6
Troconso, J.C.7
Dawson, V.L.8
Dawson, T.M.9
-
40
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
Simon-Sanchez J., Schulte C., Bras J.M., Sharma M., Gibbs J.R., Berg D., Paisan-Ruiz C., Lichtner P., Scholz S.W., Hernandez D.G., et al. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat. Genet. 2009, 41:1308-1312.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
Berg, D.6
Paisan-Ruiz, C.7
Lichtner, P.8
Scholz, S.W.9
Hernandez, D.G.10
-
41
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
42
-
-
84859187983
-
GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1
-
Stafa K., Trancikova A., Webber P.J., Glauser L., West A.B., Moore D.J. GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. PLoS Genet. 2012, 8:9.
-
(2012)
PLoS Genet.
, vol.8
, pp. 9
-
-
Stafa, K.1
Trancikova, A.2
Webber, P.J.3
Glauser, L.4
West, A.B.5
Moore, D.J.6
-
43
-
-
80051949129
-
Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein
-
Tan J., Zhang T., Jiang L., Chi J., Hu D., Pan Q., Wang D., Zhang Z. Regulation of intracellular manganese homeostasis by Kufor-Rakeb syndrome-associated ATP13A2 protein. J. Biol. Chem. 2011, 286:29654-29662.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 29654-29662
-
-
Tan, J.1
Zhang, T.2
Jiang, L.3
Chi, J.4
Hu, D.5
Pan, Q.6
Wang, D.7
Zhang, Z.8
-
44
-
-
84905646690
-
Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration
-
Tsika E., Glauser L., Moser R., Fiser A., Daniel G., Sheerin U.M., Lees A., Troncoso J.C., Lewis P.A., Bandopadhyay R., et al. Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration. Hum. Mol. Genet. 2014, 23:4612-4638.
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 4612-4638
-
-
Tsika, E.1
Glauser, L.2
Moser, R.3
Fiser, A.4
Daniel, G.5
Sheerin, U.M.6
Lees, A.7
Troncoso, J.C.8
Lewis, P.A.9
Bandopadhyay, R.10
-
45
-
-
85005851989
-
Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation
-
Tsunemi T., Krainc D. Zn2+ dyshomeostasis caused by loss of ATP13A2/PARK9 leads to lysosomal dysfunction and alpha-synuclein accumulation. Hum. Mol. Genet. 2013, 13:13.
-
(2013)
Hum. Mol. Genet.
, vol.13
, pp. 13
-
-
Tsunemi, T.1
Krainc, D.2
-
46
-
-
80052254663
-
Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death
-
Ugolino J., Fang S., Kubisch C., Monteiro M.J. Mutant Atp13a2 proteins involved in parkinsonism are degraded by ER-associated degradation and sensitize cells to ER-stress induced cell death. Hum. Mol. Genet. 2011, 20:3565-3577.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 3565-3577
-
-
Ugolino, J.1
Fang, S.2
Kubisch, C.3
Monteiro, M.J.4
-
47
-
-
77957224859
-
Viral vector-mediated overexpression of alpha-synuclein as a progressive model of Parkinson's disease
-
Ulusoy A., Decressac M., Kirik D., Bjorklund A. Viral vector-mediated overexpression of alpha-synuclein as a progressive model of Parkinson's disease. Prog. Brain Res. 2010, 184:89-111.
-
(2010)
Prog. Brain Res.
, vol.184
, pp. 89-111
-
-
Ulusoy, A.1
Decressac, M.2
Kirik, D.3
Bjorklund, A.4
-
48
-
-
84858403126
-
Deficiency of ATP13A2 leads to lysosomal dysfunction, alpha-synuclein accumulation, and neurotoxicity
-
Usenovic M., Tresse E., Mazzulli J.R., Taylor J.P., Krainc D. Deficiency of ATP13A2 leads to lysosomal dysfunction, alpha-synuclein accumulation, and neurotoxicity. J. Neurosci. 2012, 32:4240-4246.
-
(2012)
J. Neurosci.
, vol.32
, pp. 4240-4246
-
-
Usenovic, M.1
Tresse, E.2
Mazzulli, J.R.3
Taylor, J.P.4
Krainc, D.5
-
49
-
-
84865064424
-
Identification of novel ATP13A2 interactors and their role in alpha-synuclein misfolding and toxicity
-
Usenovic M., Knight A.L., Ray A., Wong V., Brown K.R., Caldwell G.A., Caldwell K.A., Stagljar I., Krainc D. Identification of novel ATP13A2 interactors and their role in alpha-synuclein misfolding and toxicity. Hum. Mol. Genet. 2012, 21:3785-3794.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 3785-3794
-
-
Usenovic, M.1
Knight, A.L.2
Ray, A.3
Wong, V.4
Brown, K.R.5
Caldwell, G.A.6
Caldwell, K.A.7
Stagljar, I.8
Krainc, D.9
|