Antifungal drug resistance evoked via RNAi-dependent epimutations

Nature

Volumn 513, Issue 7519, 2014, Pages 555-558

  Calo, Silvia ^a   Shertz Wall, Cecelia ^a   Lee, Soo Chan ^a   Bastidas, Robert J ^a   Nicolás, Francisco E ^b,c   Granek, Joshua A ^a   Mieczkowski, Piotr ^d   Torres Martínez, Santiago ^c   Ruiz Vázquez, Rosa M ^c   Cardenas, Maria E ^a   Heitman, Joseph ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Regional Campus of International Excellence Campus Mare Nostrum ^*  (Spain)

^c UNIVERSITY OF MURCIA   (Spain)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; DOUBLE STRANDED RNA; FUNGAL RNA; MESSENGER RNA; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE FKBP12; PHOSPHOPROTEIN PHOSPHATASE; TACROLIMUS; UNCLASSIFIED DRUG; FK 506 BINDING PROTEIN;

ANTIBIOTIC RESISTANCE; ENZYME ACTIVITY; FUNGAL DISEASE; GENE EXPRESSION; GENETIC ANALYSIS; INHIBITION; MICROORGANISM; MUTATION; PATHOGEN; PHENOTYPE; PHENOTYPIC PLASTICITY; PROTEIN; RNA; WILD POPULATION; YEAST;

ANTIFUNGAL RESISTANCE; ARTICLE; CAENORHABDITIS ELEGANS; EPIMUTATION; FKBA GENE; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; FUNGUS HYPHAE; GENE MUTATION; HIGH THROUGHPUT SEQUENCING; INDEL MUTATION; MUCOR CIRCINELLOIDES; NONHUMAN; PHENOTYPIC PLASTICITY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; RNA INTERFERENCE; SCHIZOSACCHAROMYCES POMBE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MUCOR; MUCORMYCOSIS; MUTATION; PHENOTYPE;

EUKARYOTA; FUNGI; MUCOR CIRCINELLOIDES;

CALCINEURIN; DRUG RESISTANCE, FUNGAL; EPIGENESIS, GENETIC; HUMANS; HYPHAE; MOLECULAR SEQUENCE DATA; MUCOR; MUCORMYCOSIS; MUTATION; PHENOTYPE; RNA INTERFERENCE; TACROLIMUS; TACROLIMUS BINDING PROTEIN 1A;

EID: 84908510460     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13575     Document Type: Article

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