The mating-related loci sexM and sexP of the zygomycetous fungus Mucor mucedo and their transcriptional regulation by trisporoid pheromones

Microbiology

Volumn 158, Issue 4, 2012, Pages 1016-1023

  Wetzel, Jana ^a   Burmester, Anke ^a   Kolbe, Melanie ^a   Wöstemeyer, Johannes ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP PROTEIN; HYBRID PROTEIN; PHEROMONE; PROTEIN SEXM; PROTEIN SEXP; RNA HELICASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; GENE LOCUS; INVERSE POLYMERASE CHAIN REACTION; MATING; MATING TYPE; MUCOR; MUCOR MUCEDO; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PHYCOMYCES BLAKESLEEANUS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REAL TIME POLYMERASE CHAIN REACTION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION REGULATION; ZYGOMYCETES;

DNA PRIMERS; DNA, FUNGAL; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GENES, MATING TYPE, FUNGAL; HIGH MOBILITY GROUP PROTEINS; MUCOR; NUCLEAR LOCALIZATION SIGNALS; PHEROMONES; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; TRANSCRIPTION, GENETIC;

FUNGI; MUCOR MUCEDO; MUCORALES; PHYCOMYCES BLAKESLEEANUS; SACCHAROMYCES CEREVISIAE;

EID: 84859129496     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/mic.0.054106-0     Document Type: Article

References (35)

1. Alvarez, M. I., Peláez, M. I. & Eslava, A. P. (1980). Recombination between ten markers in Phycomyces. Mol Gen Genet 179, 447-452.
2. Botstein, D., Falco, S. C., Stewart, S. E., Brennan, M., Scherer, S., Stinchcomb, D. T., Struhl, K. & Davis, R. W. (1979). Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments. Gene 8, 17-24.
3. Brameier, M., Krings, A. & MacCallum, R. M. (2007). NucPred-predicting nuclear localization of proteins. Bioinformatics 23, 1159-1160.
4. Bucher, P. (1990). Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J Mol Biol 212, 563-578.
5. Burmester, A. & Czempinski, K. (1994). Sequence comparison of a segment of the gene for 3-hydroxy-3-methylglutaryl-coenzyme A reductase in zygomycetes. Eur J Biochem 220, 403-408.
6. Burmester, A., Richter, M., Schultze, K., Voelz, K., Schachtschabel, D., Boland, W., Wöstemeyer, J. & Schimek, C. (2007). Cleavage of bcarotene as the first step in sexual hormone synthesis in zygomycetes is mediated by a trisporic acid regulated b-carotene oxygenase. Fungal Genet Biol 44, 1096-1108.
7. Covitz, P. A., Herskowitz, I. & Mitchell, A. P. (1991). The yeast RME1 gene encodes a putative zinc finger protein that is directly repressed by a1-alpha 2. Genes Dev 5, 1982-1989.
8. Czempinski, K., Kruft, V., Wöstemeyer, J. & Burmester, A. (1996). 4-Dihydromethyltrisporate dehydrogenase from Mucor mucedo, an enzyme of the sexual hormone pathway: purification, and cloning of the corresponding gene. Microbiology 142, 2647-2654.
9. Geiser, M., Döring, H. P., Wöstemeyer, J., Behrens, U., Tillmann, E. & Starlinger, P. (1980). A cDNA clone from Zea mays endosperm sucrose synthetase mRNA. Nucleic Acids Res 8, 6175-6188.
10. Gryganskyi, A. P., Lee, S. C., Litvintseva, A. P., Smith, M. E., Bonito, G., Porter, T. M., Anishchenko, I. M., Heitman, J. & Vilgalys, R. (2010). Structure, function, and phylogeny of the mating locus in the Rhizopus oryzae complex. PLoS ONE 5, e15273.
11. Herskowitz, I. (1988). Life cycle of the budding yeast Saccharomyces cerevisiae. Microbiol Rev 52, 536-553.
12. Hinnen, A., Hicks, J. B. & Fink, G. R. (1978). Transformation of yeast. Proc Natl Acad Sci U S A 75, 1929-1933.
13. Idnurm, A., Walton, F. J., Floyd, A. & Heitman, J. (2008). Identification of the sex genes in an early diverged fungus. Nature 451, 193-196.
14. Lee, S. C., Corradi, N., Byrnes, E. J., III, Torres-Martinez, S., Dietrich, F. S., Keeling, P. J. & Heitman, J. (2008). Microsporidia evolved from ancestral sexual fungi. Curr Biol 18, 1675-1679.
15. Lee, S. C., Ni, M., Li, W., Shertz, C. & Heitman, J. (2010). The evolution of sex: a perspective from the fungal kingdom. Microbiol Mol Biol Rev 74, 298-340.
16. Li, C. H., Cervantes, M., Springer, D. J., Boekhout, T., Ruiz-Vazquez, R. M., Torres-Martinez, S. R., Heitman, J. & Lee, S. C. (2011). Sporangiospore size dimorphism is linked to virulence of Mucor circinelloides. PLoS Pathog 7, e1002086.
17. 2ggCt Method. Methods 25, 402-408.
18. Mantovani, R. (1998). A survey of 178 NF-Y binding CCAAT boxes. Nucleic Acids Res 26, 1135-1143.
19. Mendoza-Mendoza, A., Eskova, A., Weise, C., Czajkowski, R. & Kahmann, R. (2009). Hap2 regulates the pheromone response transcription factor prf1 in Ustilago maydis. Mol Microbiol 72, 683-698.
20. Metzenberg, R. L. & Glass, N. L. (1990). Mating type and mating strategies in Neurospora. Bioessays 12, 53-59.
21. Pöggeler, S. (2001). Mating-type genes for classical strain improvements of ascomycetes. Appl Microbiol Biotechnol 56, 589-601.
22. Polaino, S., Herrador, M. M., Cerdá-Olmedo, E. & Barrero, A. F. (2010). Splitting of b-carotene in the sexual interaction of Phycomyces. Org Biomol Chem 8, 4229-4231.
23. Schilde, C., Wöstemeyer, J. & Burmester, A. (2001). Green fluorescent protein as a reporter for gene expression in the mucoralean fungus Absidia glauca. Arch Microbiol 175, 1-7.
24. Schimek, C. & Wöstemeyer, J. (2009). Carotene derivatives in sexual communication of zygomycete fungi. Phytochemistry 70, 1867-1875.
25. Schimek, C. & Wöstemeyer, J. (2010). Pheromone action in the fungal groups Chytridiomycota and Zygomycota, and in the Oomycota. In The Mycota I, 2nd edn, pp. 215-231. Edited by U. Kües & R. Fischer. Berlin, FL: Springer.
26. Schimek, C., Kleppe, K., Saleem, A. R., Voigt, K., Burmester, A. & Wöstemeyer, J. (2003). Sexual reactions in Mortierellales are mediated by the trisporic acid system. Mycol Res 107, 736-747.
27. Schimek, C., Petzold, A., Schultze, K., Wetzel, J., Wolschendorf, F., Burmester, A. & Wöstemeyer, J. (2005). 4-Dihydromethyltrisporate dehydrogenase, an enzyme of the sex hormone pathway in Mucor mucedo, is constitutively transcribed but its activity is differently regulated in (+) and (2) mating types. Fungal Genet Biol 42, 804-812.
28. Schultze, K., Schimek, C., Wöstemeyer, J. & Burmester, A. (2005). Sexuality and parasitism share common regulatory pathways in the fungus Parasitella parasitica. Gene 348, 33-44.
29. Steidl, S., Tüncher, A., Goda, H., Guder, C., Papadopoulou, N., Kobayashi, T., Tsukagoshi, N., Kato, M. & Brakhage, A. A. (2004). A single subunit of a heterotrimeric CCAAT-binding complex carries a nuclear localization signal: piggy back transport of the pre-assembled complex to the nucleus. J Mol Biol 342, 515-524.
30. Tschumper, G. & Carbon, J. (1980). Sequence of a yeast DNA fragment containing a chromosomal replicator and the TRP1 gene. Gene 10, 157-166.
31. Werkman, B. A. (1976). Localization and partial characterization of a sex-specific enzyme in homothallic and heterothallic Mucorales. Arch Microbiol 109, 209-213.
32. Wetzel, J., Scheibner, O., Burmester, A., Schimek, C. & Wöstemeyer, J. (2009). 4-dihydrotrisporin-dehydrogenase, an enzyme of the sex hormone pathway of Mucor mucedo: purification, cloning of the corresponding gene, and developmental expression. Eukaryot Cell 8, 88-95.
33. Wöstemeyer, J. (1985). Strain-dependent variation in ribosomal DNA arrangement in Absidia glauca. Eur J Biochem 146, 443-448.
34. Wöstemeyer, J., Wöstemeyer, A., Burmester, A. & Czempinski, K. (1995). Relationships between sexual processes and parasitic interactions in the host-pathogen system Absidia glauca-Parasitella parasitica. Can J Bot 73 (S1), S243-S250.
35. Wöstemeyer, J., Grünler, A., Schimek, C. & Voigt, K. (2005). Genetic regulation of carotenoid biosynthesis in fungi. In Applied Mycology and Biotechnology 5: Genes and Genomics, pp. 257-274. Edited by D. K. Arora. Amsterdam: Elsevier.