Efficacy of psychoeducational family intervention for bipolar i disorder: A controlled, multicentric, real-world study

Journal of Affective Disorders

Volumn 172, Issue , 2015, Pages 291-299

  Fiorillo, Andrea ^a   Del Vecchio, Valeria ^a   Luciano, Mario ^a   Sampogna, Gaia ^a   De Rosa, Corrado ^a   Malangone, Claudio ^a   Volpe, Umberto ^a   Bardicchia, Francesco ^b   Ciampini, Giuseppina ^c   Crocamo, Cristina ^d   Iapichino, Sonia ^e   Lampis, Debora ^f   Moroni, Anna ^g   Orlandi, Emanuele ^h   Piselli, Massimiliano ⁱ   Pompili, Enrico ^j   Veltro, Franco ^k   Carrà, Giuseppe ^l   Maj, Mario ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

^b Mental Health Centre of Grosseto   (Italy)

^c Mental Health Centre of Lanciano   (Italy)

^d UNIVERSITY OF PAVIA   (Italy)

^e Mental Health Centre of Montecatini   (Italy)

^f Mental Health Centre of Lanusei   (Italy)

^g OSPEDALE NIGUARDA CA GRANDA   (Italy)

^h Mental Health Centre of Sassuolo   (Italy)

ⁱ Mental Health Centre of Foligno   (Italy)

^j Mental Health Centre   (Italy)

^k Mental Health Department of Campobasso   (Italy)

^l UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

Bipolar I disorder; Family; Family burden; Outcome; Psychoeducation; Social functioning

Indexed keywords

ADULT; AGED; ARTICLE; BIPOLAR I DISORDER; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FAMILY THERAPY; FEMALE; HOSPITAL ADMISSION; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; MENTAL HEALTH CENTER; MULTICENTER STUDY; PSYCHOEDUCATION; SOCIAL INTERACTION; TREATMENT OUTCOME; BIPOLAR DISORDER; CLINICAL TRIAL; COGNITIVE THERAPY; HEALTH EDUCATION; METHODOLOGY; MIDDLE AGED; PROCEDURES; SCHIZOPHRENIA;

ADULT; BIPOLAR DISORDER; COGNITIVE THERAPY; FEMALE; HEALTH EDUCATION; HUMANS; ITALY; MALE; MIDDLE AGED; RESEARCH DESIGN; SCHIZOPHRENIA;

EID: 84908458815     PISSN: 01650327     EISSN: 15732517     Source Type: Journal    
DOI: 10.1016/j.jad.2014.10.021     Document Type: Article

References (82)

1. American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders- Text Revision (DSM-IV-TR) 2002 American Psychiatric Association Washington DC
2. R.J. Baldessarini, L. Tondo, G.H. Vazquez, J. Undurraga, L. Bolzani, A. Yildiz, H.K. Khalsa, M. Lai, B. Lepri, M. Lolich, P.M. Maffei, P. Salvatore, G.L. Faedda, E. Vieta, and M. Tohen Age at onset versus family history and clinical outcomes in 1.665 international bipolar-I disorder patients World Psychiatry 11 2012 40 46
3. T.A. Beentjes, P.J. Goossens, and I.E. Poslawsky Caregiver burden in bipolar hypomania and mania: a systematic review Perspect. Psychiatr. Care 48 2012 187 197
4. D. Bhugra, and A. Fiorillo Families, functioning and therapies Int. Rev. Psychiatry 24 2012 79 80
5. V. Candini, C. Buizza, C. Ferrari, M.T. Caldera, R. Ermentini, A. Ghilardi, G. Nobili, R. Pioli, M. Sabaudo, E. Sacchetti, F.M. Saviotti, G. Seggioli, A. Zanini, and G. de Girolamo Is structured group psychoeducation for bipolar patients effective in ordinary mental health services? A controlled trial in Italy J. Affect. Disord. 151 2013 149 155
6. G. Carrà, F. Bartoli, C. Crocamo, K.T. Brady, and M. Clerici Attempted suicide in people with co-occurring bipolar and substance use disorders: systematic review and meta-analysis J. Affect. Disord. 167 2014 125 135
7. G. Carrà, C.L. Cazzullo, and M. Clerici The association between expressed emotion, illness severity and subjective burden of care in relatives of patients with schizophrenia. Findings from an Italian population BMC Psychiatry 12 2012 140
8. G. Carrà, G.S. Lusignani, P. Sciarini, F. Barale, A. Marinoni, and M. Clerici And how shall we deal with adaptation and implementation of NICE schizophrenia guidelines in Italy? Epidemiol. Psichiatr. Soc. 17 2008 258 262
9. G. Carrà, C. Montomoli, M. Clerici, and C.L. Cazzullo Family interventions for schizophrenia in Italy: randomized controlled trial Eur. Arch. Psychiatry Clin. Neurosci. 257 2007 23 30
10. J.F. Clarkin, D. Carpenter, J. Hull, P. Wilner, and I. Glick Effects of psychoeducational intervention for married patients with bipolar disorder and their spouses Psychiatr. Serv. 49 1998 531 533
11. J.F. Clarkin, I.D. Glick, G.L. Haas, J.H. Spencer, A.B. Lewis, J. Peyser, N. DeMane, M. Good-Ellis, E. Harris, and V. Lestelle A randomized clinical trial of inpatient family intervention. V. Results for affective disorders J. Affect. Disord. 18 1990 17 28
12. F. Colom The evolution of psychoeducation for bipolar disorder: from lithium clinics to integrative psychoeducation World Psychiatry 13 2014 90 92
13. F. Colom, M. Reinares, I. Pacchiarotti, D. Popovic, L. Mazzarini, A. Martínez-Arán, C. Torrent, A. Rosa, R. Palomino-Otiniano, C. Franco, C.M. Bonnin, and E. Vieta Has number of previous episodes any effect on response to group psychoeducation in bipolar patients? A 5-year follow-up post hoc analysis Acta Neuropsychiatr. 22 2010 50 53
14. F. Colom, and E. Vieta Manual de Psicoeducacìon para el trastorno bipolar 2004 Ars medica Barcelona, Spain
15. F. Colom, E. Vieta, J. Sánchez-Moreno, R. Palomino-Otiniano, M. Reinares, J.M. Goikolea, A. Benabarre, and A. Martínez-Arán Group psychoeducation for stabilized bipolar disorders: 5-year outcome of a randomised clinical trial Br. J. Psychiatry 194 2009 260 265
16. K de Barros Pellegrinelli, L.F. de O Costa, K.I. Silval, V.V. Dias, M.C. Roso, M. Bandeira, F. Colom, and R.A. Moreno Efficacy of psychoeducation on symptomatic and functional recovery in bipolar disorder Acta Psychiatr. Scand. 127 2013 153 158
17. V. Del Vecchio, M. Luciano, C. Malangone, D. Giacco, C. De Rosa, G. Sampogna, L. Del Gaudio, V. Vinci, E. Di Iorio, N. Feliziani, R. Pescosolido, G. Ciampini, D. Lampis, L. De Falco, S. Biondi, E. Riva, E. Orlandi, C. Baronessa, M. Piselli, and A. Fiorillo Implementing family psychoeducational intervention for bipolar I disorder in 11 Italian Mental Health Centres J. Psychopathol. 17 2011 277 282
18. L.B. Dixon, A. Lucksted, D.R. Medoff, J. Burland, B. Stewart, A.F. Lehman, L.J. Fang, V. Sturm, C. Brown, and A. Murray-Swank Outcomes of a randomized study of a peer-taught Family-to-Family Education Program for mental illness Psychiatr. Serv. 62 2011 591 597
19. G. Fadden Research update: psychoeducational family interventions J. Fam. Ther. 20 1998 293 309
20. I.R.H. Falloon Family Management of Schizophrenia: A Controlled Study of Clinical, Social, Family and Economic Benefits 1985 John Hopkins University Press Baltimore, Maryland
21. A. Fiorillo, M. Luciano, V. Del Vecchio, G. Sampogna, C. Obradors-Tarragó, M. Maj ROAMER Consortium Priorities for mental health research in Europe: a survey among national stakeholders' associations within the ROAMER project World Psychiatry 12 2013 165 170
22. A. Fiorillo, G. Sampogna, L. Del Gaudio, M. Luciano, and V. Del Vecchio Efficacy of supportive family interventions in bipolar disorder: a review of the literature J. Psychopathol. 19 2013 134 142
23. K.K. Ganguly, R.K. Chadda, and T.B. Singh Caregiver burden and coping in schizophrenia and bipolar disorder: a qualitative study Am. J. Psychiatr. Rehabil. 13 2010 126 142
24. J.R. Geddes, and D.J. Miklowitz Treatment of bipolar disorder Lancet 11 2013 1672 1682
25. J.F. Goldberg, and M. Harrow Bipolar Disorders 1998 American Psychiatric Press Washington, Washington DC
26. G.M. Goodwin Consensus Group of the British Association for Psychopharmacology Evidence-based guidelines for treating bipolar disorder: revised second edition-recommendations from the British Association for Psychopharmacology J. Psychopharmacol. 23 2009 346 388
27. S.K. Gupta Intention-to-treat concept: a review. Perspect Clin. Res. 2 2011 109 112
28. A. Heru, and C. Ryan Depressive symptoms and family functioning in the caregivers of recently hospitalized patients with chronic / recurrent mood disorders Int. J. Psychosoc. Rehabil. 7 2002 53 60
29. N. Huxley, and R.J. Baldessarini Disability and its treatment in bipolar disorder patients Bipolar Disord. 9 2007 183 196
30. S. Jones, P. Hayward, and D. Lam Coping with Bipolar Disorder - A Guide to Living with Manic Depression 2002 One word publications Oxford, UK
31. L.P. Justo, B.G. Soares, and H.M. Calil Family interventions for bipolar disorder Cochrane Database Syst. Rev. 17 2007 CD005167
32. F. Kapczinski, V.V. Dias, M. Kauer-Sant'Anna, B.N. Frey, R. Grassi-Oliveira, F. Colom, and M. Berk Clinical implications of a staging model for bipolar disorders Exp. Rev. Neurother. 9 2009 957 966
33. S. Katotonka Consumer recovery: a call for partnership between researchers and consumers World Psychiatry 11 2012 170 171
34. E. Leclerc, R.B. Mansur, and E. Brietzke Determinants of adherence to treatment in bipolar disorder: a comprehensive review J. Affect. Disord. 149 2013 247 252
35. J. Leff Family work for schizophrenin: practical application Acta Psychiatr. Scand. 102 2000 78 82
36. H.P. Lefley Family Psychoeducation for Serious Mental Illness. Evidence-Based Practice Series 2009 Oxford University Press New York
37. M. Luciano, V. Del Vecchio, D. Giacco, C. De Rosa, C. Malangone, and A. Fiorillo A family affair? The impact of family psychoeducational interventions on depression Exp. Rev. Neurother. 12 2012 83 91
38. M. Luciano, G. Sampogna, V. Del Vecchio, D. Giacco, A. Mulè, C. De Rosa, A. Fiorillo, and M. Maj The family in Italy: cultural changes and implications for treatment Int. Rev. Psychiatry 24 2012 149 156
39. A. Lucksted, W. McFarlane, D. Downing, and L. Dixon Recent developments in family psychoeducation as an evidence-based practice J. Marital Fam. Ther. 38 2012 101 121
40. D. Lukoff, K.H. Nuechterlein, and J. Ventura Appendix A: manual for expanded Brief Psychiatric Rating Scale (BPRS) Schizophre. Bull. 12 1986 594 602
41. D.R. Lyman, L. Braude, P. George, R.H. Dougherty, A.S. Daniels, S.S. Ghose, and M.E. Delphin-Rittmon Consumer and family psychoeducation: assessing the evidence Psychiatr. Serv. 65 2014 416 428
42. K. Madigan, P. Egan, D. Brennan, S. Hill, B. Maguire, F. Horgan, C. Flood, A. Kinsella, and E. O'Callaghan A randomized controlled trial of carer-focused multi-family group psychoeducation in bipolar disorder Eur. Psychiatry 27 2012 281 284
43. L. Magliano, G. Fadden, A. Fiorillo, C. Malangone, D. Sorrentino, A. Robinson, and M. Maj Family burden and coping strategies in schizophrenia: are key relatives really different to other relatives? Acta Psychiatr. Scand. 99 1999 10 15
44. L. Magliano, A. Fiorillo, C. De Rosa, M. Maj National Mental Health Project Working Group Family burden and social network in schizophrenia vs. physical diseases: preliminary results from an Italian national study Acta Psychiatr. Scand. 113 2006 60 63
45. L. Magliano, A. Fiorillo, G. Fadden, F. Gair, M. Economou, T. Kallert, J. Schellong, M. Xavier, M. Gonçalves Pereira, F. Torres Gonzales, A. Palma-Crespo, and M. Maj Effectiveness of a psychoeducational intervention for families of patients with schizophrenia: results of a study funded by the European Commission World Psychiatry 4 2005 45 49
46. L. Magliano, A. Fiorillo, C. Malangone, C. De Rosa, and M. Maj Patient functioning and family burden in a controlled, real-world trial of family psychoeducation for schizophrenia Psychiatr. Serv. 57 2006 1784 1791
47. L. Magliano, A. Fiorillo, C. Malangone, C. De Rosa, M. Maj Family Intervention Working Group Implementing psychoeducational interventions in Italy for patients with schizophrenia and their families Psychiatr. Serv. 57 2006 266 269
48. L. Magliano, A. Orrico, A. Fiorillo, H. Del Vecchio, G. Castiello, C. Malangone, C. De Rosa, V. Capuano, M. Maj the IMDS working group Family burden in bipolar disorders: results from the Italian Mood Disorder Study (IMDS). Epidemiol Psychiatr. Sci. 18 2009 137 146
49. C. McDonald, K. Schulze, M.R. Murray, and M. Tohen Bipolar Disorder 2005 Taylor and Francis Group London, UK
50. W.R. McFarlane Multiple Family Group in the Treatment of Severe Psychiatric Disorders 2002 Guilford Press New York
51. D.J. Miklowitz The Bipolar Disorder Survival Guide: What You and Your Family Need to Know 2002 Guildford Press New York, New York
52. D.J. Miklowitz, E.L. George, J.A. Richards, T.L. Simoneau, and R.L. Suddath A randomized study of family-focused psychoeducation and pharmacotherapy in the outpatient management of bipolar disorder Arch. Gen. Psychiatry 60 2003 904 912
53. D.J. Miklowitz, and M.J. Goldstein Bipolar Disorder: A Family- Focused Treatment Approach 1997 Guilford Press New York
54. D.J. Miklowitz, and M.W. Otto Psychosocial interventions for bipolar disorder: a review of literature and introduction of the systematic treatment enhancement program Psychopharmacol. Bull. 40 2007 116 131
55. D.J. Miklowitz, and J. Scott Psychosocial treatments for bipolar disorder: cost-effectiveness, mediating mechanisms, and future directions Bipolar. Disord. 11 2009 110 122
56. D.J. Miklowitz, T.L. Simoneau, E.L. George, J.A. Richards, A. Kalbag, N. Sachs-Ericsson, and R. Suddath Family focused treatment of bipolar disorder: 1-year effects of a psychoeducational program in conjunction with pharmacotherapy Biol. Psychiatry 48 2000 582 592
57. I.W. Miller, G.I. Keitner, C.E. Ryan, L.A. Uebelacker, S.L. Johnson, and D.A. Solomon Family treatment for bipolar disorder: family impairment by treatment interactions J. Clin. Psychiatry 69 2008 732 740
58. P.L. Morosini, R. Roncone, F. Veltro, U. Palomba, and M. Casacchia Routine assessment tool in psychiatry: the questionnaire of family attitudes and burden Iran. J. Psychiatry Behav. Sci. 1 1991 95 101
59. K.T. Mueser, F. Deavers, D.L. Penn, and J.E. Cassisi Psychosocial treatments for schizophrenia Ann. Rev. Clin. Psychol. 9 2013 465 497
60. National Institute for Health and Care Excellence. 2013. Bipolar disorder. The management of bipolar disorder in adults, children and adolescents, in primary and secondary care. 〈http://www.nice.org.uk/nicemedia/live/10990/30193/30193.pdf〉
61. A.D. Ogilvie, N. Morant, and G.M Goodwin The burden on informal caregivers of people with bipolar disorders Bipolar Disord. 7 2005 25 32
62. S.V. Parikh, A. Zaretsky, S. Beaulieu, L.N. Yatham, L.T. Young, I. Patelis-Siotis, G.M. Macqueen, A. Levitt, T. Arenovich, P. Cervantes, V. Velyvis, S.H. Kennedy, and D.L. Streiner A randomized controlled trial of psychoeducation or cognitive-behavioral therapy in bipolar disorder: a Canadian Network for Mood and Anxiety treatments (CANMAT) study [CME] J. Clin. Psychiatry 73 2012 803 810
63. D.A. Perlick, D.J. Miklowitz, N. Lopez, J. Chou, C. Kalvin, V. Adzhiashvili, and A. Aronson Family-focused treatment for caregivers of patients with bipolar disorder Bipolar Disord. 12 2010 627 637
64. D.A. Perlick, R.A. Rosenheck, D.J. Mikolwitz, C. Chessick, N. Wolff, R. Kaczynski, M. Ostacher, J. Patel, R. Desai the STEP-BD Family Experience Collaborative Study Group Prevalence and correlates of burden among caregivers of patients with bipolar disorder enrolled in the Systematic Treatment Enhancement Program for Bipolar Disorder Bipolar Disord. 9 2007 262 273
65. M. Pompili, D. Harnic, X. Gonda, A. Forte, G. Dominici, M. Innamorati, K.N. Fountoulakis, G. Serafini, L. Sher, L. Janiri, Z. Rihmer, M. Amore, and P. Girardi Impact of living with bipolar patients: making sense of caregivers' burden World J. Psychiatry 22 2014 1 12
66. J. Prasko, M. Ociskova, D. Kamaradova, Z. Sedlackova, M. Cerna, B. Mainerova, and A. Sandoval Bipolar affective disorder and psychoeducation Neuro Endocrinol. Lett. 34 2013 83 96
67. B. Puschner, P. Neumann, H. Jordan, M. Slade, A. Fiorillo, D. Giacco, A. Egerházi, T. Ivánka, M.K. Bording, H.∅. Sørensen, A. Bär, W. Kawohl, S. Loos CEDAR study group Development and psychometric properties of a five-language multiperspective instrument to assess clinical decision making style in the treatment of people with severe mental illness (CDMS) BMC Psychiatry 13 2013 48
68. M. Reinares, F. Colom, A.R. Rosa, C.M. Bonnín, C. Franco, B. Solé, F. Kapczinski, and E. Vieta The impact of staging bipolar disorder on treatment outcome of family psychoeducation J. Affect. Disord. 123 2010 81 86
69. M. Reinares, F. Colom, J. Sánchez-Moreno, C. Torrent, A. Martínez-Arán, M. Comes, J.M. Goikolea, A. Benabarre, M. Salamero, and E. Vieta Impact of caregiver group psychoeducation on the course and outcome of bipolar patients in remission: a randomized controlled trial Bipolar Disord. 10 2008 511 519
70. M. Reinares, J. Sánchez-Moreno, and K.N. Fountoulakis Psychosocial interventions in bipolar disorder: what, for whom, and when J. Affect. Disord. 156 2014 46 55
71. M. Reinares, E. Vieta, F. Colom, A. Martínez-Arán, C. Torrent, M. Comes, J.M. Goikolea, A. Benabarre, and J. Sánchez-Moreno Impact of a psychoeducational family intervention on caregivers of stabilized bipolar patients Psychother. Psychosom. 73 2004 312 319
72. B.W. Rouget, and J.M. Aubry Efficacy of psychoeducational approaches on bipolar disorders: a review of the literature J. Affect. Disord. 98 2007 11 27
73. J. Scott, E. Paykel, R. Morriss, R. Bentall, P. Kinderman, T. Johnson, R. Abbott, and H. Hayhurst Cognitive-behavioural therapy for severe and recurrent bipolar disorders: randomised controlled trial Br. J. Psychiatry 188 2006 313 320
74. P. Solomon, J. Draine, and E. Mannion The impact of individualized consultation and group workshop family education interventions in ill relative outcomes J. Nerv. Ment. Dis. 184 1996 252 255
75. SPSS Inc. 2009. PASW Statistics for Windows, Version 18.0. Chicago, SPSS Inc.
76. N. Stafford, and F. Colom Purpose and effectiveness of psychoeducation in patients with bipolar disorder in a bipolar clinic setting Acta Psychiatr. Scand. Suppl. 442 2013 11 18
77. STATA, Statistical software package, Version 11.0. 2011. Stata Corp., College Station, Texas.
78. A. Steele, N. Maruyama, and I. Galynker Psychiatric symptoms in caregivers of patients with bipolar disorder: a review J. Affect. Disord. 121 2010 10 21
79. C. Torrent, M. Bonnin Cdel, A. Martínez-Arán, J. Valle, B.L. Amann, A. González-Pinto, J.M. Crespo, A. Ibáñez, M.P. Garcia-Portilla, R. Tabarés-Seisdedos, C. Arango, F. Colom, B. Solé, I. Pacchiarotti, A.R. Rosa, J.L. Ayuso-Mateos, C. Anaya, P. Fernández, R. Landín-Romero, S. Alonso-Lana, J. Ortiz-Gil, B. Segura, S. Barbeito, P. Vega, M. Fernández, A. Ugarte, M. Subirà, E. Cerrillo, N. Custal, JM. Menchón, J. Saiz-Ruiz, J.M. Rodao, S. Isella, A. Alegría, S. Al-Halabi, J. Bobes, G. Galván, P.A. Saiz, V. Balanzá-Martínez, G. Selva, I. Fuentes-Durá, P. Correa, M. Mayoral, G. Chiclana, J. Merchan-Naranjo, M. Rapado-Castro, M. Salamero, and E. Vieta Efficacy of functional remediation in bipolar disorder: a multicenter randomized controlled study Am. J. Psychiatry 170 2013 852 859
80. M.C. Viana, M.J. Gruber, V. Shahly, A. Alhamzawi, J. Alonso, L.H. Andrade, M.C. Angermeyer, C. Benjet, R. Bruffaerts, J.M. Caldas-de-Almeida, G. de Girolamo, P.d. Jonge, F. Ferry, S. Florescu, O. Gureje, J.M. Haro, H. Hinkov, C. Hu, E.G. Karam, J.P. Lepine, D. Levinson, J. Posada-Villa, N.A. Sampson, and R.C. Kessler Family burden related to mental and physical disorders in the world: results from the WHO World Mental Health (WMH) surveys Rev. Bras. Psiquiatr. 35 2013 115 125
81. H.A. Whiteford, L. Degenhardt, J. Rehm, A.J. Baxter, A.J. Ferrari, H.E. Erskine, F.J. Charlson, R.E. Norman, A.D. Flaxman, N. Johns, R. Burstein, C.J.L. Murray, and T. Vos Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2013 Lancet 382 2013 1575 1586
82. World Health Organization WHO psychiatric Disability Assessment Schedule 1988 WHO Geneva