Thiazolidone derivatives as inhibitors of chikungunya virus

European Journal of Medicinal Chemistry

Volumn 89, Issue , 2015, Pages 172-178

  Jadav, Surender Singh ^a   Sinha, Barij Nayan ^a   Hilgenfeld, Rolf ^b,c   Pastorino, Boris ^d   De Lamballerie, Xavier ^d   Jayaprakash, Venkatesan ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY   (India)

^b UNIVERSITY OF LÜBECK   (Germany)

^c German Center for Infection Research (DZIF)   (Germany)

^d AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Antiviral; Chikungunya virus; Molecular docking; nsp2 protease; Thiazolidinone

Indexed keywords

2 AMINO 5 [(2 METHYLPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(2 NITROPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(2, 4 DIHYDROXYPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(3 HYDROXYPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(3 METHYLPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(3 NITROPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(4 HYDROXYPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 2 AMINO 5 [(4 METHYLPHENYL)METHYLIDENE] 4,5 DIHYDRO 1,3 THIAZOL 4 ONE; 5 (NAPHTHALEN 2 YL METHYLIDENE) 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 (PYRIDIN 2 YL METHYLIDENE) 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 (PYRIDIN 3 YL METHYLIDENE) 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 (THIOPHEN 2 YL METHYLIDENE) 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(2 METHYLPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(2 NITROPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(4 CHLOROPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(4 CYANOPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(4 HYDROXYPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(4 METHOXYPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [(4 METHYLPHENYL)METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; 5 [[4 (DIMETHYLAMINO)PHENYL]METHYLIDENE] 2 SULFANYLIDENE 1,3 THIAZOLIDIN 4 ONE; ANTIVIRUS AGENT; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG; THIAZOLE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; CRYSTAL STRUCTURE; CULTURAL ANTHROPOLOGY; MOLECULAR DOCKING; NONHUMAN; PROTEINASE INHIBITION; VERO CELL LINE; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; CHIKUNGUNYA VIRUS; DOSE RESPONSE; DRUG EFFECTS; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTIVIRAL AGENTS; CHIKUNGUNYA VIRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 84908447953     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.10.042     Document Type: Article

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