-
1
-
-
79751504193
-
The pathogenesis of sepsis
-
Stearns-Kurosawa DJ, Osuchowski MF, Valentine C, Kurosawa S, Remick DG (2011) The pathogenesis of sepsis. Annu Rev Pathol 6: 19-48.
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 19-48
-
-
Stearns-Kurosawa, D.J.1
Osuchowski, M.F.2
Valentine, C.3
Kurosawa, S.4
Remick, D.G.5
-
3
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
Hotchkiss RS, Karl IE (2003) The pathophysiology and treatment of sepsis. N Engl J Med 348: 138-150.
-
(2003)
N Engl J Med
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
4
-
-
0036681725
-
Critical role of NK cells rather than V alpha 14(+)NKT cells in lipopolysac-charide-induced lethal shock in mice
-
Emoto M, Miyamoto M, Yoshizawa I, Emoto Y, Schaible UE, et al. (2002) Critical role of NK cells rather than V alpha 14(+)NKT cells in lipopolysac-charide-induced lethal shock in mice. J Immunol 169: 1426-1432.
-
(2002)
J Immunol
, vol.169
, pp. 1426-1432
-
-
Emoto, M.1
Miyamoto, M.2
Yoshizawa, I.3
Emoto, Y.4
Schaible, U.E.5
-
5
-
-
54049107296
-
Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response
-
Barkhausen T, Frerker C, Putz C, Pape HC, Krettek C, et al. (2008) Depletion of NK cells in a murine polytrauma model is associated with improved outcome and a modulation of the inflammatory response. Shock 30: 401-410.
-
(2008)
Shock
, vol.30
, pp. 401-410
-
-
Barkhausen, T.1
Frerker, C.2
Putz, C.3
Pape, H.C.4
Krettek, C.5
-
6
-
-
44449143573
-
NK but not CD1-restricted NKT cells facilitate systemic inflammation during polymicrobial intra-abdominal sepsis
-
Etogo AO, Nunez J, Lin CY, Toliver-Kinsky TE, Sherwood ER (2008) NK but not CD1-restricted NKT cells facilitate systemic inflammation during polymicrobial intra-abdominal sepsis. J Immunol 180: 6334-6345.
-
(2008)
J Immunol
, vol.180
, pp. 6334-6345
-
-
Etogo, A.O.1
Nunez, J.2
Lin, C.Y.3
Toliver-Kinsky, T.E.4
Sherwood, E.R.5
-
8
-
-
36248967595
-
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
-
Anderson AC, Anderson DE, Bregoli L, Hastings WD, Kassam N, et al. (2007) Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 318: 1141-1143.
-
(2007)
Science
, vol.318
, pp. 1141-1143
-
-
Anderson, A.C.1
Anderson, D.E.2
Bregoli, L.3
Hastings, W.D.4
Kassam, N.5
-
9
-
-
79955863018
-
HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: Implications for progression to neurological complications
-
Ndhlovu LC, Leal FE, Hasenkrug AM, Jha AR, Carvalho KI, et al. (2011) HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications. PLoS Negl Trop Dis 5: e1030.
-
(2011)
PLoS Negl Trop Dis
, vol.5
, pp. e1030
-
-
Ndhlovu, L.C.1
Leal, F.E.2
Hasenkrug, A.M.3
Jha, A.R.4
Carvalho, K.I.5
-
10
-
-
77549086947
-
T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B
-
Ju Y, Hou N, Meng J, Wang X, Zhang X, et al. (2010) T cell immunoglobulin- and mucin-domain-containing molecule-3 (Tim-3) mediates natural killer cell suppression in chronic hepatitis B. J Hepatol 52: 322-329.
-
(2010)
J Hepatol
, vol.52
, pp. 322-329
-
-
Ju, Y.1
Hou, N.2
Meng, J.3
Wang, X.4
Zhang, X.5
-
11
-
-
30044434075
-
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
-
Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, et al. (2005) The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 6: 1245-1252.
-
(2005)
Nat Immunol
, vol.6
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
-
12
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, Ndhlovu LC, Barbour JD, Sheth PM, Jha AR, et al. (2008) Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med 205: 2763-2779.
-
(2008)
J Exp Med
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
Ndhlovu, L.C.2
Barbour, J.D.3
Sheth, P.M.4
Jha, A.R.5
-
13
-
-
40849120400
-
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
-
Seki M, Oomizu S, Sakata KM, Sakata A, Arikawa T, et al. (2008) Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 127: 78-88.
-
(2008)
Clin Immunol
, vol.127
, pp. 78-88
-
-
Seki, M.1
Oomizu, S.2
Sakata, K.M.3
Sakata, A.4
Arikawa, T.5
-
14
-
-
59249099786
-
Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice
-
Nobumoto A, Oomizu S, Arikawa T, Katoh S, Nagahara K, et al. (2009) Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice. Clin Immunol 130: 322-330.
-
(2009)
Clin Immunol
, vol.130
, pp. 322-330
-
-
Nobumoto, A.1
Oomizu, S.2
Arikawa, T.3
Katoh, S.4
Nagahara, K.5
-
15
-
-
2442704124
-
T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
-
Khademi M, Illes Z, Gielen AW, Marta M, Takazawa N, et al. (2004) T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J Immunol 172: 7169-7176.
-
(2004)
J Immunol
, vol.172
, pp. 7169-7176
-
-
Khademi, M.1
Illes, Z.2
Gielen, A.W.3
Marta, M.4
Takazawa, N.5
-
16
-
-
84860337409
-
Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity
-
Ndhlovu LC, Lopez-Verges S, Barbour JD, Jones RB, Jha AR, et al. (2012) Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity. Blood 119: 3734-3743.
-
(2012)
Blood
, vol.119
, pp. 3734-3743
-
-
Ndhlovu, L.C.1
Lopez-Verges, S.2
Barbour, J.D.3
Jones, R.B.4
Jha, A.R.5
-
17
-
-
84859192882
-
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
-
Gleason MK, Lenvik TR, McCullar V, Felices M, O'Brien MS, et al. (2012) Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9. Blood 119: 3064-3072.
-
(2012)
Blood
, vol.119
, pp. 3064-3072
-
-
Gleason, M.K.1
Lenvik, T.R.2
McCullar, V.3
Felices, M.4
O'Brien, M.S.5
-
18
-
-
84862789324
-
Increased expression of T cell immunoglobulin- and mucin domain-containing molecule-3 on natural killer cells in atherogenesis
-
Hou N, Zhao D, Liu Y, Gao L, Liang X, et al. (2012) Increased expression of T cell immunoglobulin- and mucin domain-containing molecule-3 on natural killer cells in atherogenesis. Atherosclerosis 222: 67-73.
-
(2012)
Atherosclerosis
, vol.222
, pp. 67-73
-
-
Hou, N.1
Zhao, D.2
Liu, Y.3
Gao, L.4
Liang, X.5
-
19
-
-
84874269629
-
T cell Ig mucin-3 promotes homeostasis of sepsis by negatively regulating the TLR response
-
Yang X, Jiang X, Chen G, Xiao Y, Geng S, et al. (2013) T cell Ig mucin-3 promotes homeostasis of sepsis by negatively regulating the TLR response. J Immunol 190: 2068-2079.
-
(2013)
J Immunol
, vol.190
, pp. 2068-2079
-
-
Yang, X.1
Jiang, X.2
Chen, G.3
Xiao, Y.4
Geng, S.5
-
20
-
-
84896542597
-
Tim-3 signaling pathway as a novel negative mediator in lipopolysaccharide-induced endotoxic shock
-
Wang F, Hou H, Xu L, Jane M, Peng J, et al. (2014) Tim-3 signaling pathway as a novel negative mediator in lipopolysaccharide-induced endotoxic shock. Hum Immunol 75: 470-478.
-
(2014)
Hum Immunol
, vol.75
, pp. 470-478
-
-
Wang, F.1
Hou, H.2
Xu, L.3
Jane, M.4
Peng, J.5
-
21
-
-
42449151214
-
Functions of natural killer cells
-
Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S (2008) Functions of natural killer cells. Nat Immunol 9: 503-510.
-
(2008)
Nat Immunol
, vol.9
, pp. 503-510
-
-
Vivier, E.1
Tomasello, E.2
Baratin, M.3
Walzer, T.4
Ugolini, S.5
-
22
-
-
78650970845
-
Innate or adaptive immunity? The example of natural killer cells
-
Vivier E, Raulet DH, Moretta A, Caligiuri MA, Zitvogel L, et al. (2011) Innate or adaptive immunity? The example of natural killer cells. Science 331: 44-49.
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
Caligiuri, M.A.4
Zitvogel, L.5
-
23
-
-
79959503061
-
The role of natural killer cells in sepsis
-
Chiche L, Forel JM, Thomas G, Farnarier C, Vely F, et al. (2011) The role of natural killer cells in sepsis. J Biomed Biotechnol 2011: 986491.
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 986491
-
-
Chiche, L.1
Forel, J.M.2
Thomas, G.3
Farnarier, C.4
Vely, F.5
-
24
-
-
80054718314
-
Early natural killer cell counts in blood predict mortality in severe sepsis
-
Andaluz-Ojeda D, Iglesias V, Bobillo F, Almansa R, Rico L, et al. (2011) Early natural killer cell counts in blood predict mortality in severe sepsis. Crit Care 15: R243.
-
(2011)
Crit Care
, vol.15
, pp. R243
-
-
Andaluz-Ojeda, D.1
Iglesias, V.2
Bobillo, F.3
Almansa, R.4
Rico, L.5
-
25
-
-
77952630881
-
Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection
-
Gogos C, Kotsaki A, Pelekanou A, Giannikopoulos G, Vaki I, et al. (2010) Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. Crit Care 14: R96.
-
(2010)
Crit Care
, vol.14
, pp. R96
-
-
Gogos, C.1
Kotsaki, A.2
Pelekanou, A.3
Giannikopoulos, G.4
Vaki, I.5
-
26
-
-
34447623218
-
Early changes of CD4-positive lymphocytes and NK cells in patients with severe Gram-negative sepsis
-
Giamarellos-Bourboulis EJ, Tsaganos T, Spyridaki E, Mouktaroudi M, Plachouras D, et al. (2006) Early changes of CD4-positive lymphocytes and NK cells in patients with severe Gram-negative sepsis. Crit Care 10: R166.
-
(2006)
Crit Care
, vol.10
, pp. R166
-
-
Giamarellos-Bourboulis, E.J.1
Tsaganos, T.2
Spyridaki, E.3
Mouktaroudi, M.4
Plachouras, D.5
-
27
-
-
60849114014
-
Compensatory anti-inflammatory response syndrome
-
Adib-Conquy M, Cavaillon JM (2009) Compensatory anti-inflammatory response syndrome. Thromb Haemost 101: 36-47.
-
(2009)
Thromb Haemost
, vol.101
, pp. 36-47
-
-
Adib-Conquy, M.1
Cavaillon, J.M.2
-
28
-
-
84856101211
-
Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes
-
Kanzaki M, Wada J, Sugiyama K, Nakatsuka A, Teshigawara S, et al. (2012) Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes. Endocrinology 153: 612-620.
-
(2012)
Endocrinology
, vol.153
, pp. 612-620
-
-
Kanzaki, M.1
Wada, J.2
Sugiyama, K.3
Nakatsuka, A.4
Teshigawara, S.5
-
29
-
-
40849083349
-
Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts
-
Wang F, He W, Yuan J, Wu K, Zhou H, et al. (2008) Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts. Transpl Immunol 19: 12-19.
-
(2008)
Transpl Immunol
, vol.19
, pp. 12-19
-
-
Wang, F.1
He, W.2
Yuan, J.3
Wu, K.4
Zhou, H.5
-
30
-
-
41249096396
-
The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft
-
Wang F, He W, Zhou H, Yuan J, Wu K, et al. (2007) The Tim-3 ligand galectin-9 negatively regulates CD8+ alloreactive T cell and prolongs survival of skin graft. Cell Immunol 250: 68-74.
-
(2007)
Cell Immunol
, vol.250
, pp. 68-74
-
-
Wang, F.1
He, W.2
Zhou, H.3
Yuan, J.4
Wu, K.5
-
31
-
-
84865439684
-
Tumor immunity times out: TIM-3 and HMGB1
-
Tang D, Lotze MT (2012) Tumor immunity times out: TIM-3 and HMGB1. Nat Immunol 13: 808-810.
-
(2012)
Nat Immunol
, vol.13
, pp. 808-810
-
-
Tang, D.1
Lotze, M.T.2
-
32
-
-
77957744369
-
Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity
-
Sakuishi K, Apetoh L, Sullivan JM, Blazar BR, Kuchroo VK, et al. (2010) Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity. J Exp Med 207: 2187-2194.
-
(2010)
J Exp Med
, vol.207
, pp. 2187-2194
-
-
Sakuishi, K.1
Apetoh, L.2
Sullivan, J.M.3
Blazar, B.R.4
Kuchroo, V.K.5
-
33
-
-
84860347302
-
Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in patients with chronic hepatitis B
-
Wu W, Shi Y, Li S, Zhang Y, Liu Y, et al. (2012) Blockade of Tim-3 signaling restores the virus-specific CD8(+) T-cell response in patients with chronic hepatitis B. Eur J Immunol 42: 1180-1191.
-
(2012)
Eur J Immunol
, vol.42
, pp. 1180-1191
-
-
Wu, W.1
Shi, Y.2
Li, S.3
Zhang, Y.4
Liu, Y.5
-
34
-
-
69449091993
-
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
-
Golden-Mason L, Palmer BE, Kassam N, Townshend-Bulson L, Livingston S, et al. (2009) Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol 83: 9122-9130.
-
(2009)
J Virol
, vol.83
, pp. 9122-9130
-
-
Golden-Mason, L.1
Palmer, B.E.2
Kassam, N.3
Townshend-Bulson, L.4
Livingston, S.5
-
35
-
-
0028274201
-
Essential role for natural killer cells in the lethal lipopolysaccharide-induced Shwartzman-like reaction in mice
-
Heremans H, Dillen C, van Damme J, Billiau A (1994) Essential role for natural killer cells in the lethal lipopolysaccharide-induced Shwartzman-like reaction in mice. Eur J Immunol 24: 1155-1160.
-
(1994)
Eur J Immunol
, vol.24
, pp. 1155-1160
-
-
Heremans, H.1
Dillen, C.2
Van Damme, J.3
Billiau, A.4
-
36
-
-
0035111806
-
Role of T cells and gamma interferon during induction of hypersensitivity to lipopolysaccharide by toxic shock syndrome toxin 1 in mice
-
Dinges MM, Schlievert PM (2001) Role of T cells and gamma interferon during induction of hypersensitivity to lipopolysaccharide by toxic shock syndrome toxin 1 in mice. Infect Immun 69: 1256-1264.
-
(2001)
Infect Immun
, vol.69
, pp. 1256-1264
-
-
Dinges, M.M.1
Schlievert, P.M.2
-
37
-
-
21344456795
-
Activated cytotoxic T cells and NK cells in severe sepsis and septic shock and their role in multiple organ dysfunction
-
Zeerleder S, Hack CE, Caliezi C, van Mierlo G, Eerenberg-Belmer A, et al. (2005) Activated cytotoxic T cells and NK cells in severe sepsis and septic shock and their role in multiple organ dysfunction. Clin Immunol 116: 158-165.
-
(2005)
Clin Immunol
, vol.116
, pp. 158-165
-
-
Zeerleder, S.1
Hack, C.E.2
Caliezi, C.3
Van Mierlo, G.4
Eerenberg-Belmer, A.5
-
38
-
-
84857616057
-
Increased granzyme levels in cytotoxic T lymphocytes are associated with disease severity in emergency department patients with severe sepsis
-
Napoli AM, Fast LD, Gardiner F, Nevola M, Machan JT (2012) Increased granzyme levels in cytotoxic T lymphocytes are associated with disease severity in emergency department patients with severe sepsis. Shock 37: 257-262.
-
(2012)
Shock
, vol.37
, pp. 257-262
-
-
Napoli, A.M.1
Fast, L.D.2
Gardiner, F.3
Nevola, M.4
Machan, J.T.5
-
39
-
-
57349092199
-
Relationship between CD107a expression and cytotoxic activity
-
Aktas E, Kucuksezer UC, Bilgic S, Erten G, Deniz G (2009) Relationship between CD107a expression and cytotoxic activity. Cell Immunol 254: 149-154.
-
(2009)
Cell Immunol
, vol.254
, pp. 149-154
-
-
Aktas, E.1
Kucuksezer, U.C.2
Bilgic, S.3
Erten, G.4
Deniz, G.5
-
40
-
-
84908397938
-
Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade
-
da Silva IP, Gallois A, Jimenez-Baranda S, Khan S, Anderson AC, et al. (2014) Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade. Cancer Immunol Res 2: 410-422.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 410-422
-
-
Da Silva, I.P.1
Gallois, A.2
Jimenez-Baranda, S.3
Khan, S.4
Anderson, A.C.5
-
41
-
-
17044413706
-
Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways
-
Hotchkiss RS, Osmon SB, Chang KC, Wagner TH, Coopersmith CM, et al. (2005) Accelerated lymphocyte death in sepsis occurs by both the death receptor and mitochondrial pathways. J Immunol 174: 5110-5118.
-
(2005)
J Immunol
, vol.174
, pp. 5110-5118
-
-
Hotchkiss, R.S.1
Osmon, S.B.2
Chang, K.C.3
Wagner, T.H.4
Coopersmith, C.M.5
|