Streptolysin O and NAD-glycohydrolase prevent phagolysosome acidification and promote group A Streptococcus survival in macrophages

mBio

Volumn 5, Issue 5, 2014, Pages

  Bastiat Sempe, Benedicte ^a   Love, John F ^a,b   Lomayesva, Natalie ^a   Wessels, Michael R ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NICOTINAMIDE ADENINE DINUCLEOTIDE NUCLEOSIDASE; STREPTOLYSIN O; BACTERIAL PROTEIN; STREPTOLYSIN;

ACIDIFICATION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CYTOSOL; CYTOTOXICITY; EPITHELIUM CELL; MACROPHAGE; NONHUMAN; PHAGOLYSOSOME; PROTEIN FUNCTION; REGULATORY MECHANISM; STREPTOCOCCUS GROUP A; CELL LINE; CONFOCAL MICROSCOPY; DRUG EFFECTS; HUMAN; INTRACELLULAR MEMBRANE; METABOLISM; MICROBIOLOGY; MOLECULAR CLONING; PHAGOCYTOSIS; PHAGOSOME; STREPTOCOCCUS PYOGENES;

STREPTOCOCCUS SP. 'GROUP A';

BACTERIAL PROTEINS; CELL LINE; CLONING, MOLECULAR; CYTOSOL; EPITHELIAL CELLS; HUMANS; INTRACELLULAR MEMBRANES; MACROPHAGES; MICROSCOPY, CONFOCAL; NAD+ NUCLEOSIDASE; PHAGOCYTOSIS; PHAGOSOMES; STREPTOCOCCUS PYOGENES; STREPTOLYSINS;

EID: 84908409077     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.01690-14     Document Type: Article

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