Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function

Science Signaling

Volumn 7, Issue 347, 2014, Pages ra97-

  Liu, Xiaolei ^a,b   Pasula, Satish ^a   Song, Hoogeun ^a   Tessneer, Kandice L ^a   Dong, Yunzhou ^a   Hahn, Scott ^a   Yago, Tadayuki ^a   Brophy, Megan L ^a,b   Chang, Baojun ^a   Cai, Xiaofeng ^a   Wu, Hao ^a   McManus, John ^a   Ichise, Hirotake ^c   Georgescu, Constantin ^a   Wren, Jonathan D ^a,b   Griffin, Courtney ^a,b   Xia, Lijun ^a,b   Srinivasan, R Sathish ^a   Chen, Hong ^a,b  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; EPSIN; EPSIN 1; EPSIN 2; UBIQUITIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 3; 3-(4-DIMETHYLAMINO-NAPHTHALEN-1-YLMETHYLENE)-1,3-DIHYDRO-INDOL-2-ONE; EPSIN 2 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; INDOLE DERIVATIVE; LIGAND; NAPHTHALENE DERIVATIVE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; ENDOCYTOSIS; ENDOTHELIUM CELL; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LYMPH VESSEL; LYMPHANGIOGENESIS; LYMPHATIC DRAINAGE; LYMPHATIC SYSTEM; LYMPHATIC VALVE; MEDIATOR; MESENTERIC ARTERY; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN FUNCTION; SHEAR FLOW; SIGNAL TRANSDUCTION; SPATIOTEMPORAL ANALYSIS; ALLELE; ANIMAL; C57BL MOUSE; CELL PROLIFERATION; CELL SEPARATION; CHEMISTRY; CROSS BREEDING; CYTOLOGY; FEMALE; FLOW CYTOMETRY; KNOCKOUT MOUSE; LYMPH NODE; LYMPHEDEMA; METABOLISM; PATHOLOGY; PLASMID; TIME FACTOR;

MUS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALLELES; ANIMALS; CELL PROLIFERATION; CELL SEPARATION; CROSSES, GENETIC; ENDOCYTOSIS; ENDOTHELIAL CELLS; FEMALE; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; INDOLES; LIGANDS; LYMPH NODES; LYMPHATIC SYSTEM; LYMPHEDEMA; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NAPHTHALENES; PLASMIDS; SIGNAL TRANSDUCTION; TIME FACTORS; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3;

EID: 84908399275     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005413     Document Type: Article

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