Prostasin interacts with the epithelial Na+ channel and facilitates cleavage of the γ-subunit by a second protease

American Journal of Physiology - Renal Physiology

Volumn 307, Issue 9, 2014, Pages F1080-F1087

  Carattino, Marcelo D ^a   Mueller, Gunhild M ^a   Palmer, Lawrence G ^b   Frindt, Gustavo ^b   Rued, Anna C ^a   Hughey, Rebecca P ^a   Kleyman, Thomas R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Amiloride; Channel activating protease 1; Epithelial sodium channel; Prostasin; Proteases

Indexed keywords

ALPHA EPITHELIAL SODIUM CHANNEL; APROTININ; EPITHELIAL SODIUM CHANNEL; GAMMA EPITHELIAL SODIUM CHANNEL; PROSTASIN; PROTEINASE; SERINE PROTEINASE; UNCLASSIFIED DRUG; FURIN; PROTEIN SUBUNIT; SALT INTAKE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; SALT INTAKE; SODIUM ABSORPTION; SODIUM RESTRICTION; XENOPUS LAEVIS; ADMINISTRATION AND DOSAGE; ANIMAL; GENETICS; HEK293 CELL LINE; MALE; METABOLISM; PROTEIN SUBUNIT; SPRAGUE DAWLEY RAT;

ANIMALS; EPITHELIAL SODIUM CHANNELS; FEMALE; FURIN; HEK293 CELLS; HUMANS; MALE; OOCYTES; PROTEIN SUBUNITS; RATS, SPRAGUE-DAWLEY; SERINE ENDOPEPTIDASES; SODIUM CHLORIDE, DIETARY; XENOPUS LAEVIS;

EID: 84908388869     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00157.2014     Document Type: Article

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