Stepwise priming by acidic pH and a high K+ concentration is required for efficient uncoating of influenza a virus cores after penetration

Journal of Virology

Volumn 88, Issue 22, 2014, Pages 13029-13046

  Stauffer, Sarah ^a   Feng, Yuehan ^a   Nebioglu, Firat ^a   Heilig, Rosalie ^a   Picotti, Paola ^a   Helenius, Ari ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

MATRIX 1 PROTEIN; MATRIX 2 PROTEIN; MATRIX PROTEIN; POTASSIUM ION; RIBONUCLEOPROTEIN; SODIUM ION; UNCLASSIFIED DRUG; VALINOMYCIN; VIRUS NUCLEOPROTEIN; VIRUS PROTEIN; M2 PROTEIN, INFLUENZA A VIRUS; POTASSIUM; PROTEIN BINDING;

ACIDIFICATION; ACIDITY; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL VACUOLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENDOSOME; IN VITRO STUDY; INFLUENZA A; INFLUENZA VIRUS A; NONHUMAN; PH MEASUREMENT; PROTEIN CLEAVAGE; VIRUS CELL INTERACTION; VIRUS CORE; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS STRAIN; VIRUS UNCOATING; ANIMAL; DRUG EFFECTS; HUMAN; INFLUENZA A VIRUS; METABOLISM; PH; PHYSIOLOGY; PROTEIN CONFORMATION; VIROLOGY;

ANIMALS; ENDOSOMES; HUMANS; HYDROGEN-ION CONCENTRATION; INFLUENZA A VIRUS; POTASSIUM; PROTEIN BINDING; PROTEIN CONFORMATION; VIRAL MATRIX PROTEINS; VIRUS UNCOATING;

EID: 84908377302     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01430-14     Document Type: Article

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