Effects of bisoprolol and losartan treatment in the hypertrophic and failing right heart

Journal of Cardiac Failure

Volumn 20, Issue 11, 2014, Pages 864-873

  Andersen, Stine ^a   Schultz, Jacob Gammelgaard ^a   Andersen, Asger ^a   Ringgaard, Steffen ^a   Nielsen, Jan M ^a   Holmboe, Sarah ^a   Vildbrad, Mads D ^a   De Man, Frances S ^b   Bogaard, Harm J ^b   Vonk Noordegraaf, Anton ^b   Nielsen Kudsk, Jens Erik ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

angiotensin II receptor blocker; beta adrenergic receptor blocker; pulmonary hypertension; Right ventricular dysfunction

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BISOPROLOL; BRAIN NATRIURETIC PEPTIDE; LOSARTAN; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASCITES; CAPILLARY DENSITY; CARDIOVASCULAR MORTALITY; COMPARATIVE STUDY; CONTROLLED STUDY; CORONARY ARTERY SURGERY; DISEASE COURSE; DRUG EFFECT; HEART HYPERTROPHY; HEART MUSCLE FIBROSIS; HEART OUTPUT; HEART RATE; HEART RIGHT VENTRICLE FAILURE; HYDROTHORAX; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PROTEIN BLOOD LEVEL; PULMONARY TRUNK BANDING; RAT; SYSTOLIC BLOOD PRESSURE; TRICUSPID VALVE REGURGITATION; ANIMAL; DISEASE MODEL; DRUG COMBINATION; DRUG EFFECTS; HEART FAILURE; HEART RIGHT VENTRICLE FUNCTION; HYPERTROPHY, RIGHT VENTRICULAR; PATHOPHYSIOLOGY; WISTAR RAT;

ADRENERGIC BETA-1 RECEPTOR ANTAGONISTS; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BISOPROLOL; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG THERAPY, COMBINATION; HEART FAILURE; HYPERTROPHY, RIGHT VENTRICULAR; LOSARTAN; MALE; RATS; RATS, WISTAR; VENTRICULAR FUNCTION, RIGHT;

EID: 84908367963     PISSN: 10719164     EISSN: 15328414     Source Type: Journal    
DOI: 10.1016/j.cardfail.2014.08.003     Document Type: Article

References (39)

1. N.F. Voelkel, R.A. Quaife, L.A. Leinwand, R.J. Barst, M.D. McGoon, and D.R. Meldrum Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure Circulation 114 2006 1883 1891
2. G.E. d'Alonzo, R.J. Barst, S.M. Ayres, E.H. Bergofsky, B.H. Brundage, and K.M. Detre Survival in patients with primary pulmonary hypertension. Results from a national prospective registry Ann Intern Med 115 1991 343 349
3. M.L. Handoko, F.S. de Man, C.P. Allaart, W.J. Paulus, N. Westerhof, and A. Vonk-Noordegraaf Perspectives on novel therapeutic strategies for right heart failure in pulmonary arterial hypertension: lessons from the left heart Eur Respir Rev 19 2010 72 82
4. M.C. van de Veerdonk, T. Kind, J.T. Marcus, G.-J. Mauritz, M.W. Heymans, and H.J. Bogaard Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy J Am Coll Cardiol 58 2011 2511 2519
5. J.N. Cohn, G. Tognoni Valsartan Heart Failure Trial Investigators A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure N Engl J Med 345 2001 1667 1675
6. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF) Lancet 353 1999 2001 2007
7. F.S. de Man, L. Tu, M.L. Handoko, S. Rain, G. Ruiter, and C. François Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension Am J Respir Crit Care Med 186 2012 780 789
8. S. Mak, K.K. Witte, A. Al-Hesayen, J.J. Granton, and J.D. Parker Cardiac sympathetic activation in patients with pulmonary arterial hypertension Am J Physiol Regul Integr Comp Physiol 302 2012 R1153 R1157
9. A. Ciarka, V. Doan, S. Velez-Roa, R. Naeije, and P. van de Borne Prognostic significance of sympathetic nervous system activation in pulmonary arterial hypertension Am J Respir Crit Care Med 181 2010 1269 1275
10. P.R. Forfia, S.C. Mathai, M.R. Fisher, T. Housten-Harris, A.R. Hemnes, and H.C. Champion Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension Am J Respir Crit Care Med 177 2008 1364 1369
11. H.J. Bogaard, R. Natarajan, S. Mizuno, A. Abbate, P.J. Chang, and V.Q. Chau Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats Am J Respir Crit Care Med 182 2010 652 660
12. M. Ishikawa, N. Sato, K. Asai, T. Takano, and K. Mizuno Effects of a pure alpha/beta-adrenergic receptor blocker on monocrotaline-induced pulmonary arterial hypertension with right ventricular hypertrophy in rats Circ J 73 2009 2337 2341
13. F.S. de Man, M.L. Handoko, J.J. van Ballegoij, I. Schalij, S.J. Bogaards, and P.E. Postmus Bisoprolol delays progression towards right heart failure in experimental pulmonary hypertension Circ Heart Fail 5 2012 97 105
14. M.K. Friedberg, M.Y. Cho, J. Li, R.S. Assad, M. Sun, and S. Rohailla Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased TGFβ1 signaling and is abrogated by angiotensin receptor blockade Am J Respir Cell Mol Biol 49 2013 1019 1028
15. J.L. Segar, T.D. Scholz, K.A. Bedell, O.M. Smith, D.J. Huss, and E.N. Guillery Angiotensin AT1 receptor blockade fails to attenuate pressure-overload cardiac hypertrophy in fetal sheep Am J Physiol 273 1997 R1501 R1508
16. M.A. Borgdorff, B. Bartelds, M.G. Dickinson, P. Steendijk, and R.M.F. Berger A cornerstone of heart failure treatment is not effective in experimental right ventricular failure Int J Cardiol 169 2013 183 189
17. T. Nagayama, S. Hsu, M. Zhang, N. Koitabashi, D. Bedja, and K.L. Gabrielson Pressure-overload magnitude-dependence of the anti-hypertrophic efficacy of PDE5A inhibition J Mol Cell Cardiol 46 2009 560 567
18. M. Burnier Angiotensin II type 1 receptor blockers Circulation 103 2001 904 912
19. A. Andersen, J.M. Nielsen, S. Holmboe, M.D. Vildbrad, and J.E. Nielsen-Kudsk The effects of cyclic guanylate cyclase stimulation on right ventricular hypertrophy and failure alone and in combination with phosphodiesterase-5 inhibition J Cardiovasc Pharmacol 62 2013 167 173
20. H.J. Bogaard, R. Natarajan, S.C. Henderson, C.S. Long, D. Kraskauskas, and L. Smithson Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure Circulation 120 2009 1951 1960
21. M.U. Braun, P. Szalai, R.H. Strasser, and M.M. Borst Right ventricular hypertrophy and apoptosis after pulmonary artery banding: regulation of PKC isozymes Cardiovasc Res 59 2003 658 667
22. M. Bustamante-Labarta, S. Perrone, R.L. La Fuente De, P. Stutzbach, R.P. de la Hoz, and A. Torino Right atrial size and tricuspid regurgitation severity predict mortality or transplantation in primary pulmonary hypertension J Am Soc Echocardiogr 15 2002 1160 1164
23. H.J. Bogaard, K. Abe, A. Vonk Noordegraaf, and N.F. Voelkel The right ventricle under pressure: cellular and molecular mechanisms of right-heart failure in pulmonary hypertension Chest 135 2009 794 804
24. B.D. Lowes, W. Minobe, W.T. Abraham, M.N. Rizeq, T.J. Bohlmeyer, and R.A. Quaife Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium J Clin Invest 100 1997 2315 2324
25. M. Sano, T. Minamino, H. Toko, H. Miyauchi, M. Orimo, and Y. Qin p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload Nature 446 2007 444 448
26. N. Nagaya, T. Nishikimi, M. Uematsu, T. Satoh, S. Kyotani, and F. Sakamaki Plasma brain natriuretic peptide as a prognostic indicator in patients with primary pulmonary hypertension Circulation 102 2000 865 870
27. Y. Ohta, K. Watanabe, M. Nakazawa, T. Yamamoto, M. Ma, and K. Fuse Carvedilol enhances atrial and brain natriuretic peptide mRNA expression and release in rat heart J Cardiovasc Pharmacol 36 2000 S19 S23
28. M. Patrizio, M. Musumeci, T. Stati, P. Fasanaro, S. Palazzesi, and L. Catalano Propranolol causes a paradoxical enhancement of cardiomyocyte foetal gene response to hypertrophic stimuli Br J Pharmacol 152 2007 216 222
29. M.E. Davis, A.M. Richards, M.G. Nicholls, T.G. Yandle, C.M. Frampton, and R.W. Troughton Introduction of metoprolol increases plasma B-type cardiac natriuretic peptides in mild, stable heart failure Circulation 113 2006 977 985
30. S.-I. Usui, A. Yao, M. Hatano, O. Kohmoto, T. Takahashi, and R. Nagai Upregulated neurohumoral factors are associated with left ventricular remodeling and poor prognosis in rats with monocrotaline-induced pulmonary arterial hypertension Circ J 70 2006 1208 1215
31. K.M. Chin, and G. Coghlan Characterizing the right ventricle: advancing our knowledge Am J Cardiol 110 2012 3S 8S
32. S. Holverda, C.T.-J. Gan, J.T. Marcus, P.E. Postmus, A. Boonstra, and A. Vonk Noordegraaf Impaired stroke volume response to exercise in pulmonary arterial hypertension J Am Coll Cardiol 47 2006 1732 1733
33. A. Peacock, and K. Ross Pulmonary hypertension: a contraindication to the use of β-adrenoceptor blocking agents Thorax 65 2010 454 455
34. M. Koide, B.A. Carabello, C.C. Conrad, J.M. Buckley, G. DeFreyte, and M. Barnes Hypertrophic response to hemodynamic overload: role of load vs renin-angiotensin system activation Am J Physiol 276 1999 H350 H358
35. N.W. Morrell, K.G. Morris, and K.R. Stenmark Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension Am J Physiol 269 1995 H1186 H1194
36. M.A. Alpert, T.A. Pressly, V. Mukerji, C.R. Lambert, and B. Mukerji Short- and long-term hemodynamic effects of captopril in patients with pulmonary hypertension and selected connective tissue disease Chest 102 1992 1407 1412
37. H. Ikram, A.H. Maslowski, M.G. Nicholls, E.A. Espiner, and F.T. Hull Haemodynamic and hormonal effects of captopril in primary pulmonary hypertension Br Heart J 48 1982 541 545
38. J. Therrien, Y. Provost, J. Harrison, M. Connelly, H. Kaemmerer, and G.D. Webb Effect of angiotensin receptor blockade on systemic right ventricular function and size: A small, randomized, placebo-controlled study Int J Cardiol 129 2008 187 192
39. T. van der Bom, M.M. Winter, B.J. Bouma, M. Groenink, H.W. Vliegen, and P.G. Pieper The effect of valsartan on the systemic right ventricular function: a double-blind randomized placebo-controlled pilot trial Circulation 127 2013 322 330