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Volumn 62, Issue 2, 2013, Pages 167-173

The effects of cyclic guanylate cyclase stimulation on right ventricular hypertrophy and failure alone and in combination with phosphodiesterase-5 inhibition

Author keywords

heart failure; hypertrophy; phosphodiesterase inhibitors; pulmonary hypertension; Right heart

Indexed keywords

4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; CYCLIC GMP; GUANYLATE CYCLASE; PHOSPHODIESTERASE V; SILDENAFIL;

EID: 84883305305     PISSN: 01602446     EISSN: 15334023     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318294a1cf     Document Type: Article
Times cited : (14)

References (32)
  • 2
    • 3142777629 scopus 로고    scopus 로고
    • Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    • McLaughlin VV, Presberg KW, Doyle RL, et al. Prognosis of pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines. Chest. 2004;126:78S-92S.
    • (2004) Chest. , vol.126
    • McLaughlin, V.V.1    Presberg, K.W.2    Doyle, R.L.3
  • 3
    • 19944428363 scopus 로고    scopus 로고
    • CGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism
    • Takimoto E, Champion HC, Belardi D, et al. cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism. Circ Res. 2005;96:100-109.
    • (2005) Circ Res. , vol.96 , pp. 100-109
    • Takimoto, E.1    Champion, H.C.2    Belardi, D.3
  • 4
    • 0035956914 scopus 로고    scopus 로고
    • A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy
    • Kishimoto I, Rossi K, Garbers DL. A genetic model provides evidence that the receptor for atrial natriuretic peptide (guanylyl cyclase-A) inhibits cardiac ventricular myocyte hypertrophy. Proc Natl Acad Sci U S A. 2001;98:2703-2706.
    • (2001) Proc Natl Acad Sci U S A. , vol.98 , pp. 2703-2706
    • Kishimoto, I.1    Rossi, K.2    Garbers, D.L.3
  • 5
    • 84865468239 scopus 로고    scopus 로고
    • Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle
    • Borgdorff MA, Bartelds B, Dickinson MG, et al. Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle. Eur J Heart Fail. 2012;14:1067-1074.
    • (2012) Eur J Heart Fail. , vol.14 , pp. 1067-1074
    • Borgdorff, M.A.1    Bartelds, B.2    Dickinson, M.G.3
  • 6
    • 56349169853 scopus 로고    scopus 로고
    • Effects of phosphodiesterase-5 inhibition by sildenafil in the pressure overloaded right heart
    • Andersen A, Nielsen JM, Peters CD, et al. Effects of phosphodiesterase-5 inhibition by sildenafil in the pressure overloaded right heart. Eur J Heart Fail. 2008;10:1158-1165.
    • (2008) Eur J Heart Fail. , vol.10 , pp. 1158-1165
    • Andersen, A.1    Nielsen, J.M.2    Peters, C.D.3
  • 7
    • 62349088023 scopus 로고    scopus 로고
    • Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling
    • Schäfer S, Ellinghaus P, Janssen W, et al. Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling. Cardiovasc Res. 2009;82:30-39.
    • (2009) Cardiovasc Res. , vol.82 , pp. 30-39
    • Schäfer, S.1    Ellinghaus, P.2    Janssen, W.3
  • 9
    • 10744233302 scopus 로고    scopus 로고
    • Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats
    • Schermuly RT, Kreisselmeier KP, Ghofrani HA, et al. Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats. Am J Respir Crit Care Med. 2004;169:39-45.
    • (2004) Am J Respir Crit Care Med. , vol.169 , pp. 39-45
    • Schermuly, R.T.1    Kreisselmeier, K.P.2    Ghofrani, H.A.3
  • 10
    • 0033058382 scopus 로고    scopus 로고
    • Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man
    • Walker DK, Ackland MJ, James GC, et al. Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man. Xenobiotica. 1999; 29:297-310.
    • (1999) Xenobiotica. , vol.29 , pp. 297-310
    • Walker, D.K.1    Ackland, M.J.2    James, G.C.3
  • 11
    • 0035826261 scopus 로고    scopus 로고
    • NO-independent regulatory site on soluble guanylate cyclase
    • Stasch JP, Becker EM, Alonso-Alija C, et al. NO-independent regulatory site on soluble guanylate cyclase. Nature. 2001;410:212-215.
    • (2001) Nature. , vol.410 , pp. 212-215
    • Stasch, J.P.1    Becker, E.M.2    Alonso-Alija, C.3
  • 12
    • 0036178227 scopus 로고    scopus 로고
    • Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: In vivo studies
    • Stasch JP, Dembowsky K, Perzborn E, et al. Cardiovascular actions of a novel NO-independent guanylyl cyclase stimulator, BAY 41-8543: in vivo studies. Br J Pharmacol. 2002;135:344-355.
    • (2002) Br J Pharmacol. , vol.135 , pp. 344-355
    • Stasch, J.P.1    Dembowsky, K.2    Perzborn, E.3
  • 13
    • 33748748913 scopus 로고    scopus 로고
    • Sequence of echocardiographic changes during development of right ventricular failure in rat
    • Hardziyenka M, Campian ME, de Bruin-Bon HA, et al. Sequence of echocardiographic changes during development of right ventricular failure in rat. J Am Soc Echocardiogr. 2006;19:1272-1279.
    • (2006) J Am Soc Echocardiogr. , vol.19 , pp. 1272-1279
    • Hardziyenka, M.1    Campian, M.E.2    De Bruin-Bon, H.A.3
  • 14
    • 77956713444 scopus 로고    scopus 로고
    • Validation of high-resolution echocardiography and magnetic resonance imaging vs high-fidelity catheterization in experimental pulmonary hypertension
    • Urboniene D, Haber I, Fang YH, et al. Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2010;299:L401-L412.
    • (2010) Am J Physiol Lung Cell Mol Physiol. , vol.299
    • Urboniene, D.1    Haber, I.2    Fang, Y.H.3
  • 15
    • 0345401521 scopus 로고
    • Multiple comparison procedures: The practical solution
    • Saville DJ. Multiple comparison procedures: The practical solution. Am Stat. 1990;44:174-180.
    • (1990) Am Stat. , vol.44 , pp. 174-180
    • Saville, D.J.1
  • 16
    • 77954910405 scopus 로고    scopus 로고
    • Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension
    • Ghio S, Klersy C, Magrini G, et al. Prognostic relevance of the echocardiographic assessment of right ventricular function in patients with idiopathic pulmonary arterial hypertension. Int J Cardiol. 2010;140:272-278.
    • (2010) Int J Cardiol. , vol.140 , pp. 272-278
    • Ghio, S.1    Klersy, C.2    Magrini, G.3
  • 17
    • 22044445138 scopus 로고    scopus 로고
    • Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: Correlations with the degree of hypertrophy
    • Faber MJ, Dalinghaus M, Lankhuizen IM, et al. Proteomic changes in the pressure overloaded right ventricle after 6 weeks in young rats: Correlations with the degree of hypertrophy. Proteomics. 2005;5:2519-2530.
    • (2005) Proteomics. , vol.5 , pp. 2519-2530
    • Faber, M.J.1    Dalinghaus, M.2    Lankhuizen, I.M.3
  • 18
    • 72449124776 scopus 로고    scopus 로고
    • Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure
    • Bogaard HJ, Natarajan R, Henderson SC, et al. Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure. Circulation. 2009;120:1951-1960.
    • (2009) Circulation. , vol.120 , pp. 1951-1960
    • Bogaard, H.J.1    Natarajan, R.2    Henderson, S.C.3
  • 19
    • 61449084450 scopus 로고    scopus 로고
    • Pressure-overload magnitudedependence of the anti-hypertrophic efficacy of PDE5A inhibition
    • Nagayama T, Hsu S, Zhang M, et al. Pressure-overload magnitudedependence of the anti-hypertrophic efficacy of PDE5A inhibition. J Mol Cell Cardiol. 2009;46:560-567.
    • (2009) J Mol Cell Cardiol. , vol.46 , pp. 560-567
    • Nagayama, T.1    Hsu, S.2    Zhang, M.3
  • 20
    • 47949087086 scopus 로고    scopus 로고
    • Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil
    • Nagayama T, Zhang M, Hsu S, et al. Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil. J Pharmacol Exp Ther. 2008;326: 380-387.
    • (2008) J Pharmacol Exp Ther. , vol.326 , pp. 380-387
    • Nagayama, T.1    Zhang, M.2    Hsu, S.3
  • 21
    • 61749089404 scopus 로고    scopus 로고
    • Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice
    • Takimoto E, Koitabashi N, Hsu S, et al. Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest. 2009;119: 408-420.
    • (2009) J Clin Invest. , vol.119 , pp. 408-420
    • Takimoto, E.1    Koitabashi, N.2    Hsu, S.3
  • 22
    • 20044363270 scopus 로고    scopus 로고
    • Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
    • Takimoto E, Champion HC, Li M, et al. Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med. 2005;11:214-222.
    • (2005) Nat Med. , vol.11 , pp. 214-222
    • Takimoto, E.1    Champion, H.C.2    Li, M.3
  • 23
    • 77957322681 scopus 로고    scopus 로고
    • BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats
    • Thorsen LB, Eskildsen-Helmond Y, Zibrandtsen H, et al. BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats. Eur J Pharmacol. 2010;647:147-154.
    • (2010) Eur J Pharmacol. , vol.647 , pp. 147-154
    • Thorsen, L.B.1    Eskildsen-Helmond, Y.2    Zibrandtsen, H.3
  • 24
    • 2442651359 scopus 로고    scopus 로고
    • A decade of discoveries in cardiac biology
    • Olson EN. A decade of discoveries in cardiac biology. Nat Med. 2004; 10:467-474.
    • (2004) Nat Med. , vol.10 , pp. 467-474
    • Olson, E.N.1
  • 25
    • 34547611337 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility
    • Nagendran J, Archer SL, Soliman D, et al. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007;116:238-248.
    • (2007) Circulation. , vol.116 , pp. 238-248
    • Nagendran, J.1    Archer, S.L.2    Soliman, D.3
  • 26
    • 84859628031 scopus 로고    scopus 로고
    • Differential expression of PDE5 in failing and non-failing human myocardium
    • Shan X, Quaile MP, Monk JK, et al. Differential expression of PDE5 in failing and non-failing human myocardium. Circ Heart Fail. 2012;5:79-86.
    • (2012) Circ Heart Fail. , vol.5 , pp. 79-86
    • Shan, X.1    Quaile, M.P.2    Monk, J.K.3
  • 27
    • 0037465434 scopus 로고    scopus 로고
    • Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: Structural deterioration and compensatory mechanisms
    • Hein S, Arnon E, Kostin S, et al. Progression from compensated hypertrophy to failure in the pressure-overloaded human heart: Structural deterioration and compensatory mechanisms. Circulation. 2003;107: 984-991.
    • (2003) Circulation. , vol.107 , pp. 984-991
    • Hein, S.1    Arnon, E.2    Kostin, S.3
  • 28
    • 67650547955 scopus 로고    scopus 로고
    • Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart
    • Masuyama H, Tsuruda T, Sekita Y, et al. Pressure-independent effects of pharmacological stimulation of soluble guanylate cyclase on fibrosis in pressure-overloaded rat heart. Hypertens Res. 2009;32:597-603.
    • (2009) Hypertens Res. , vol.32 , pp. 597-603
    • Masuyama, H.1    Tsuruda, T.2    Sekita, Y.3
  • 29
    • 0021894599 scopus 로고
    • The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation
    • Ignarro LJ, Kadowitz PJ. The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation. Annu Rev Pharmacol Toxicol. 1985;25:171-191.
    • (1985) Annu Rev Pharmacol Toxicol. , vol.25 , pp. 171-191
    • Ignarro, L.J.1    Kadowitz, P.J.2
  • 30
    • 79958128614 scopus 로고    scopus 로고
    • Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease
    • Stasch JP, Pacher P, Evgenov OV. Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease. Circulation. 2011;123:2263-2273.
    • (2011) Circulation. , vol.123 , pp. 2263-2273
    • Stasch, J.P.1    Pacher, P.2    Evgenov, O.V.3
  • 31
    • 78649616051 scopus 로고    scopus 로고
    • Effects of heart rate and anesthetic timing on high-resolution echocardiographic assessment under isoflurane anesthesia in mice
    • Wu J, Bu L, Gong H, et al. Effects of heart rate and anesthetic timing on high-resolution echocardiographic assessment under isoflurane anesthesia in mice. J Ultrasound Med. 2010;29:1771-1778.
    • (2010) J Ultrasound Med. , vol.29 , pp. 1771-1778
    • Wu, J.1    Bu, L.2    Gong, H.3
  • 32
    • 0036080246 scopus 로고    scopus 로고
    • Impact of anesthesia on cardiac function during echocardiography in mice
    • Roth DM, Swaney JS, Dalton ND, et al. Impact of anesthesia on cardiac function during echocardiography in mice. Am J Physiol Heart Circ Physiol. 2002;282:H2134-H2140.
    • (2002) Am J Physiol Heart Circ Physiol. , vol.282
    • Roth, D.M.1    Swaney, J.S.2    Dalton, N.D.3


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