Serum irisin levels, precocious myocardial infarction, and healthy exceptional longevity

American Journal of Medicine

Volumn 127, Issue 9, 2014, Pages 888-890

  Emanuele, Enzo ^a   Minoretti, Piercarlo ^a   Pareja Galeano, Helios ^b   Sanchis Gomar, Fabian ^b   Garatachea, Nuria ^c,d   Lucia, Alejandro ^e  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITY OF ZARAGOZA   (Spain)

^d Instituto de Investigación Hospital 12 de Octubre ^*  (Spain)

^e UNIVERSIDAD EUROPEA DE MADRID   (Spain)

Author keywords

Centenarians; Longevity; Myocardial infarction; Myokines

Indexed keywords

IRISIN; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; FIBRONECTIN; FNDC5 PROTEIN, HUMAN;

ACUTE HEART INFARCTION; ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; LONGEVITY; MAJOR CLINICAL STUDY; MALE; MUSCLE MASS; SKELETAL MUSCLE; VERY ELDERLY; BLOOD; CASE CONTROL STUDY; HEART INFARCTION; MULTIVARIATE ANALYSIS; MYOKINES; NORMAL HUMAN; PHYSIOLOGY; STATISTICAL MODEL;

CENTENARIANS; LONGEVITY; MYOCARDIAL INFARCTION; MYOKINES;

ADULT; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBRONECTINS; HEALTHY VOLUNTEERS; HUMANS; LOGISTIC MODELS; LONGEVITY; MALE; MULTIVARIATE ANALYSIS; MYOCARDIAL INFARCTION;

EID: 84908340703     PISSN: 00029343     EISSN: 15557162     Source Type: Journal    
DOI: 10.1016/j.amjmed.2014.04.025     Document Type: Article

References (27)

1. M.A. Febbraio, and B.K. Pedersen Contraction-induced myokine production and release: is skeletal muscle an endocrine organ? Exerc Sport Sci Rev 33 2005 114 119
2. H. Duzova Skeletal muscle, myokines and health Med Science 1 2012 211 231
3. P. Bostrom, J. Wu, and M.P. Jedrychowski A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis Nature 481 2012 463 468
4. S.A. Polyzos, J. Kountouras, K. Shields, and C.S. Mantzoros Irisin: a renaissance in metabolism? Metabolism 62 2013 1037 1044
5. B.M. Spiegelman Banting lecture 2012: regulation of adipogenesis: toward new therapeutics for metabolic disease Diabetes 62 2013 1774 1782
6. F. Sanchis-Gomar The skeletal muscle-metabolism axis in prostate-cancer therapy N Engl J Med 367 2013 2257 2258
7. F. Sanchis-Gomar, G. Lippi, S. Mayero, C. Perez-Quilis, and J.L. Garcia-Gimenez Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes J Diabetes 4 2012 196
8. K. Hojlund, and P. Bostrom Irisin in obesity and type 2 diabetes J Diabetes Complications 27 2013 303 304
9. F. Sanchis-Gomar, and C. Perez-Quilis The p38-PGC-1alpha-irisin-betatrophin axis: exploring new pathways in insulin resistance Adipocyte 3 2014 67 68
10. U. Elbelt, T. Hofmann, and A. Stengel Irisin: what promise does it hold? Curr Opin Clin Nutr Metab Care 16 2013 541 547
11. F. Villarroya Irisin, turning up the heat Cell Metab 15 2013 277 278
12. F. Sanchis-Gomar, and C. Perez-Quilis Irisinemia: a novel concept to coin in clinical medicine? Ann Nutr Metab 63 2013 60 61
13. G.M. Reaven Insulin resistance: the link between obesity and cardiovascular disease Med Clin North Am 95 2011 875 892
14. T. Kuloglu, S. Aydin, and M.N. Eren Irisin: a potentially candidate marker for myocardial infarction Peptides 55C 2014 85 91
15. M.J. Berger, and T.J. Doherty Sarcopenia: prevalence, mechanisms, and functional consequences Interdiscip Top Gerontol 37 2010 94 114
16. P.A. Bostrom, and J.M. Fernandez-Real Metabolism: irisin, the metabolic syndrome and follistatin in humans Nat Rev Endocrinol 10 2014 11 12
17. J.Y. Huh, G. Panagiotou, and V. Mougios FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise Metabolism 61 2012 1725 1738
18. A. Stengel, T. Hofmann, M. Goebel-Stengel, U. Elbelt, P. Kobelt, and B.F. Klapp Circulating levels of irisin in patients with anorexia nervosa and different stages of obesity-correlation with body mass index Peptides 39 2013 125 130
19. J.M. Moreno-Navarrete, F. Ortega, and M. Serrano Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance J Clin Endocrinol Metab 98 2013 E769 E778
20. Y.K. Choi, M.K. Kim, and K.H. Bae Serum irisin levels in new-onset type 2 diabetes Diabetes Res Clin Pract 100 2013 96 101
21. J.J. Liu, M.D. Wong, and W.C. Toy Lower circulating irisin is associated with type 2 diabetes mellitus J Diabetes Complications 27 2013 365 369
22. K.H. Park, L. Zaichenko, and M. Brinkoetter Circulating irisin in relation to insulin resistance and the metabolic syndrome J Clin Endocrinol Metab 98 2013 4899 4907
23. M.T. Vamvini, K.N. Aronis, and G. Panagiotou Irisin mRNA and circulating levels in relation to other myokines in healthy and morbidly obese humans Eur J Endocrinol 169 2013 829 834
24. F. Sanchis-Gomar, R. Alis, H. Pareja-Galeano, M. Romagnoli, and C. Perez-Quilis Inconsistency in circulating Irisin levels: what is really happening? Horm Metab Res 46 2014 1 6
25. F. Sanchis-Gomar, R. Alis, and H. Pareja-Galeano Circulating irisin levels are not correlated with BMI, age, and other biological parameters in obese and diabetic patients Endocrine 46 2014 674 677
26. K.S. Rana, M. Arif, and E.J. Hill Plasma irisin levels predict telomere length in healthy adults Age (Dordr) 36 2014 995 1001
27. S. Brouilette, R.K. Singh, J.R. Thompson, A.H. Goodall, and N.J. Samani White cell telomere length and risk of premature myocardial infarction Arterioscler Thromb Vasc Biol 23 2003 842 846