The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

PLoS Pathogens

Volumn 10, Issue 10, 2014, Pages

  Bertuzzi, Margherita ^a   Schrettl, Markus ^b,c   Alcazar Fuoli, Laura ^d   Cairns, Timothy C ^e   Muñoz, Alberto ^a   Walker, Louise A ^f   Herbst, Susanne ^g   Safari, Maryam ^a   Cheverton, Angela M ^g   Chen, Dan ^h   Liu, Hong ⁱ   Saijo, Shinobu ^j   Fedorova, Natalie D ^h   Armstrong James, Darius ^g   Munro, Carol A ^f   Read, Nick D ^a   Filler, Scott G ⁱ   Espeso, Eduardo A ^k   Nierman, William C ^h   Haas, Hubertus ^b   Bignell, Elaine M ^a   more..

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c NOVARTIS PHARMA AG   (Switzerland)

^d INSTITUTO DE SALUD CARLOS III   (Spain)

^e UNIVERSITY OF EXETER   (United Kingdom)

^f UNIVERSITY OF ABERDEEN   (United Kingdom)

^g IMPERIAL COLLEGE LONDON   (United Kingdom)

^h NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

^j CHIBA UNIVERSITY   (Japan)

^k CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPAIN; CASPOFUNGIN; CD16 ANTIGEN; CHROMIUM 51; CONCANAVALIN A; CYCLOPHOSPHAMIDE; DECTIN 1; ECHINOCANDIN; FLUORESCEIN ISOTHIOCYANATE; LACTATE DEHYDROGENASE; NYSTATIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PACC; TRANSCRIPTOME; UNCLASSIFIED DRUG; FUNGAL PROTEIN; PACC PROTEIN, ASPERGILLUS;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANION EXCHANGE CHROMATOGRAPHY; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; CELL ADHESION ASSAY; CELL INVASION; CELL MEMBRANE TRANSPORT; COLONY FORMING UNIT; CONTROLLED STUDY; DENSITOMETRY; DRUG SENSITIVITY; EPITHELIAL MONOLAYER; EPITHELIUM CELL; FLUORESCENCE ACTIVATED CELL SORTING; FUNGAL CELL WALL; FUNGAL STRUCTURES; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INTERNALIZATION; LEUKOPENIA; LUNG ASPERGILLOSIS; LUNG LAVAGE; MALE; MONOLAYER CULTURE; MOUSE; NONHUMAN; PH; PHENOTYPE; POLYMERASE CHAIN REACTION; RESPIRATORY EPITHELIUM; SURVIVAL; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; METABOLISM; MICROBIOLOGY;

ASPERGILLUS FUMIGATUS;

ANIMALS; ASPERGILLUS FUMIGATUS; EPITHELIAL CELLS; FUNGAL PROTEINS; HYDROGEN-ION CONCENTRATION; MICE; PULMONARY ASPERGILLOSIS; TRANSCRIPTION FACTORS;

EID: 84908333934     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004413     Document Type: Article

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