Protein competition switches the function of COP9 from self-renewal to differentiation

Nature

Volumn 514, Issue 7521, 2014, Pages 233-236

  Pan, Lei ^a,b   Wang, Su ^a,c   Lu, Tinglin ^d   Weng, Changjiang ^a   Song, Xiaoqing ^a   Park, Joseph K ^e,f   Sun, Jin ^d   Yang, Zhi Hao ^d   Yu, Junjing ^a,b   Tang, Hong ^b   McKearin, Dennis M ^e,f   Chamovitz, Daniel A ^g   Ni, Jianquan ^d   Xie, Ting ^a,c  

^a STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b INSTITUTE OF BIOPHYSICS   (China)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d TSINGHUA UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^g TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

BAM PROTEIN, DROSOPHILA; BGCN PROTEIN, DROSOPHILA; COP9 SIGNALOSOME; CSN4 PROTEIN, DROSOPHILA; CSN5 PROTEIN, DROSOPHILA; DNA HELICASE; DROSOPHILA PROTEIN; MULTIPROTEIN COMPLEX; NEDD8 PROTEIN, DROSOPHILA; PEPTIDE HYDROLASE; SIGNAL PEPTIDE; UBIQUITIN;

ANIMAL; ARTICLE; BINDING COMPETITION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DROSOPHILA MELANOGASTER; FEMALE; MALE; METABOLISM; OVARY; PROTEIN BINDING; STEM CELL;

ANIMALS; BINDING, COMPETITIVE; CELL DIFFERENTIATION; CELL PROLIFERATION; DNA HELICASES; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MULTIPROTEIN COMPLEXES; OVARY; PEPTIDE HYDROLASES; PROTEIN BINDING; STEM CELLS; UBIQUITINS;

EID: 84908326265     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13562     Document Type: Article

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