Lack of formyl peptide receptor 1 and 2 leads to more severe inflammation and higher mortality in mice with of pneumococcal meningitis

Immunology

Volumn 143, Issue 3, 2014, Pages 447-461

  Oldekamp, Sandra ^a   Pscheidl, Sebastian ^a   Kress, Eugenia ^a   Soehnlein, Oliver ^b   Jansen, Sandra ^a   Pufe, Thomas ^a   Wang, Ji Ming ^c   Tauber, Simone C ^d   Brandenburg, Lars Ove ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

Bacterial meningitis; Formyl peptide receptor; Glia cell; Innate immunity; Streptococcus pneumoniae

Indexed keywords

ANTIINFLAMMATORY AGENT; CHEMOKINE; CYTOKINE; FORMYLPEPTIDE RECEPTOR; FORMYLPEPTIDE RECEPTOR 1; FORMYLPEPTIDE RECEPTOR 2; POLYPEPTIDE ANTIBIOTIC AGENT; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; FORMYL PEPTIDE RECEPTOR 2, MOUSE; FPR1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GROWTH; BACTERIAL LOAD; BACTERIAL MENINGITIS; CELL DENSITY; CELL VIABILITY; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FRONTAL CORTEX; GENE EXPRESSION; GLIA CELL; HIPPOCAMPUS; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; MALE; MICROGLIA; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PNEUMOCOCCAL MENINGITIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; ANIMAL; BRAIN; CELL COUNT; CELL SURVIVAL; DEFICIENCY; DISEASE MODEL; GENETICS; GLIA; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; MICROBIOLOGY; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ANIMALS; BACTERIAL LOAD; BIOMARKERS; BRAIN; CELL COUNT; CELL SURVIVAL; CHEMOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IMMUNITY, INNATE; MALE; MENINGITIS, PNEUMOCOCCAL; MICE; MICE, KNOCKOUT; NEUROGLIA; NEUTROPHIL INFILTRATION; RECEPTORS, FORMYL PEPTIDE; SEVERITY OF ILLNESS INDEX;

EID: 84908301356     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12324     Document Type: Article

References (49)

1. Traore Y, Tameklo TA, Njanpop-Lafourcade BM et al. Incidence, seasonality, age distribution, and mortality of pneumococcal meningitis in Burkina Faso and Togo. Clin Infect Dis 2009; 48(Suppl. 2):S181-9.
2. Gessner BD, Mueller JE, Yaro S. African meningitis belt pneumococcal disease epidemiology indicates a need for an effective serotype 1 containing vaccine, including for older children and adults. BMC Infect Dis 2010; 10:22.
3. Schuchat A, Robinson K, Wenger JD, Harrison LH, Farley M, Reingold AL, Lefkowitz L, Perkins BA. Bacterial meningitis in the United States in 1995. Active Surveillance Team. N Engl J Med 1997; 337:970-6.
4. Koedel U, Klein M, Pfister HW. New understandings on the pathophysiology of bacterial meningitis. Curr Opin Infect Dis 2010; 23:217-23.
5. Mariani MM, Kielian T. Microglia in infectious diseases of the central nervous system. J Neuroimmune Pharmacol 2009; 4:448-61.
6. Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. J Neurochem 2006; 99:1-12.
7. Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol 2007; 81:1-5.
8. Carp H. Mitochondrial N-formylmethionyl proteins as chemoattractants for neutrophils. J Exp Med 1982; 155:264-75.
9. Zhang Q, Raoof M, Chen Y et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 2010; 464:104-7.
10. Gao JL, Chen H, Filie JD, Kozak CA, Murphy PM. Differential expansion of the Nformylpeptide receptor gene cluster in human and mouse. Genomics 1998; 51:270-6.
11. He HQ, Liao D, Wang ZG, Wang ZL, Zhou HC, Wang MW, Ye RD. Functional characterization of three mouse formyl peptide receptors. Mol Pharmacol 2013; 83:389-98.
12. Migeotte I, Communi D, Parmentier M. Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses. Cytokine Growth Factor Rev 2006; 17:501-19.
13. Brandenburg LO, Konrad M, Wruck CJ, Koch T, Lucius R, Pufe T. Functional and physical interactions between formyl-peptide-receptors and scavenger receptor MARCO and their involvement in amyloid b1-42-induced signal transduction in glial cells. J Neurochem 2010; 113:749-60.
14. Cattaneo F, Guerra G, Ammendola R. Expression and signaling of formyl-peptide receptors in the brain. Neurochem Res 2010; 35:2018-26.
15. Liu M, Chen K, Yoshimura T et al. Formylpeptide receptors are critical for rapid neutrophil mobilization in host defense against Listeria monocytogenes. Sci Rep 2012; 2:786.
16. Gao JL, Lee EJ, Murphy PM. Impaired antibacterial host defense in mice lacking the Nformylpeptide receptor. J Exp Med 1999; 189:657-62.
17. Braun BJ, Slowik A, Leib SL et al. The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis. J Neuroinflammation 2011; 8:11.
18. Dufton N, Hannon R, Brancaleone V et al. Anti-inflammatory role of the murine formyl- peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation. J Immunol 2010; 184:2611-9.
19. Chen K, Le Y, Liu Y et al. A critical role for the G protein-coupled receptor mFPR2 in airway inflammation and immune responses. J Immunol 2010; 184:3331-5.
20. Brandenburg LO, Varoga D, Nicolaeva N et al. Expression and regulation of antimicrobial peptide rCRAMP after bacterial infection in primary rat meningeal cells. J Neuroimmunol 2009; 217:55-64.
21. McCarthy KD, de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol 1980; 85:890-902.
22. Slowik A, Merres J, Elfgen A, Jansen S, Mohr F, Wruck CJ, Pufe T, Brandenburg LO. Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE) - and amyloid b1-42-induced signal transduction in glial cells. Mol Neurodegener 2012; 7:55.
23. Gerber J, Raivich G, Wellmer A, Noeske C, Kunst T, Werner A, Bruck W, Nau R. A mouse model of Streptococcus pneumoniae meningitis mimicking several features of human disease. Acta Neuropathol 2001; 101:499-508.
24. Liebetanz D, Gerber J, Schiffner C, Schutze S, Klinker F, Jarry H, Nau R, Tauber SC. Pre-infection physical exercise decreases mortality and stimulates neurogenesis in bacterial meningitis. J Neuroinflamm 2012; 9:168.
25. Tauber SC, Stadelmann C, Spreer A, Bruck W, Nau R, Gerber J. Increased expression of BDNF and proliferation of dentate granule cells after bacterial meningitis. J Neuropathol Exp Neurol 2005; 64:806-15.
26. Merres J, Hoss J, Albrecht LJ et al. Role of the cathelicidin-related antimicrobial peptide in inflammation and mortality in a mouse model of bacterial meningitis. J Innate Immun 2014; 6:205-18.
27. Brandenburg LO, Jansen S, Albrecht LJ, Merres J, Gerber J, Pufe T, Tauber SC. CpG oligodeoxynucleotides induce the expression of the antimicrobial peptide cathelicidin in glial cells. J Neuroimmunol 2013; 255:18-31.
28. Buschmann JP, Berger K, Awad H, Clarner T, Beyer C, Kipp M. Inflammatory response and chemokine expression in the white matter corpus callosum and gray matter cortex region during cuprizone-induced demyelination. J Mol Neurosci 2012; 48:66-76.
29. Kettenmann H, Hanisch UK, Noda M, Verkhratsky A. Physiology of microglia. Physiol Rev 2011; 91:461-553.
30. Brandenburg L-O, Merres J, Albrecht L-J, Varoga D, Pufe T. Antimicrobial peptides:multifunctional drugs for different applications. Polymers 2012; 4:539-60.
31. Gallo RL, Kim KJ, Bernfield M, Kozak CA, Zanetti M, Merluzzi L, Gennaro R. Identification of CRAMP, a cathelin-related antimicrobial peptide expressed in the embryonic and adult mouse. J Biol Chem 1997; 272:13088-93.
32. Hanke ML, Kielian T. Toll-like receptors in health and disease in the brain: mechanisms and therapeutic potential. Clin Sci (Lond) 2011; 121:367-87.
33. Perrier S, Darakhshan F, Hajduch E. IL-1 receptor antagonist in metabolic diseases: Dr Jekyll or Mr Hyde? FEBS Lett 2006; 580:6289-94.
34. Cuadrado A, Rojo AI. Heme oxygenase-1 as a therapeutic target in neurodegenerative diseases and brain infections. Curr Pharm Des 2008; 14:429-42.
35. Yadav A, Saini V, Arora S. MCP-1: chemoattractant with a role beyond immunity: a review. Clin Chim Acta 2010; 411:1570-9.
36. Mirabelli-Badenier M, Braunersreuther V, Viviani GL, Dallegri F, Quercioli A, Veneselli E, Mach F, Montecucco F. CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke. Thromb Haemost 2011; 105:409-20.
37. Cattaneo F, Parisi M, Ammendola R. Distinct signaling cascades elicited by different formyl Peptide receptor 2 (FPR2) agonists. Int J Mol Sci 2013; 14:7193-230.
38. Brandenburg LO, Koch T, Sievers J, Lucius R. Internalization of PrP106-126 by the formyl-peptide-receptor-like-1 in glial cells. J Neurochem 2007; 101:718-28.
39. Le Y, Murphy PM, Wang JM. Formyl-peptide receptors revisited. Trends Immunol 2002; 23:541-8.
40. - mice with experimental pneumococcal meningitis. BMC Infect Dis 2007; 7:25.
41. Gauthier JF, Fortin A, Bergeron Y, Dumas MC, Champagne ME, Bergeron MG. Differential contribution of bacterial N-formyl-methionyl-leucyl- phenylalanine and hostderived CXC chemokines to neutrophil infiltration into pulmonary alveoli during murine pneumococcal pneumonia. Infect Immun 2007; 75:5361-7.
42. Chen K, Iribarren P, Hu J et al. Activation of Toll-like receptor 2 on microglia promotes cell uptake of Alzheimer disease-associated amyloid β peptide. J Biol Chem 2006; 281:3651-9.
43. Chen K, Zhang L, Huang J, Gong W, Dunlop NM, Wang JM. Cooperation between NOD2 and Toll-like receptor 2 ligands in the up-regulation of mouse mFPR2, a G-protein- coupled Aβ42 peptide receptor, in microglial cells. J Leukoc Biol 2008; 83:1467-75.
44. Lee HY, Kim SD, Shim JW, Yun J, Kim K, Bae YS. Activation of formyl peptide receptor like-1 by serum amyloid A induces CCL2 production in human umbilical vein endothelial cells. Biochem Biophys Res Commun 2009; 380:313-7.
45. Gouwy M, Struyf S, Verbeke H, Put W, Proost P, Opdenakker G, van Damme J. CC chemokine ligand-2 synergizes with the nonchemokine G protein-coupled receptor ligand fMLP in monocyte chemotaxis, and it cooperates with the TLR ligand LPS via induction of CXCL8. J Leukoc Biol 2009; 86:671-80.
46. Chen K, Liu M, Liu Y et al. Signal relay by CC chemokine receptor 2 (CCR2) and formylpeptide receptor 2 (Fpr2) in the recruitment of monocyte-derived dendritic cells in allergic airway inflammation. J Biol Chem 2013; 288:16262-73.
47. Amor S, Puentes F, Baker D, van der Valk P. Inflammation in neurodegenerative diseases. Immunology 2010; 129:154-69.
48. Ransohoff RM, Brown MA. Innate immunity in the central nervous system. J Clin Invest 2012; 122:1164-71.
49. Finsen B, Owens T. Innate immune responses in central nervous system inflammation. FEBS Lett 2011; 585:3806-12.