Direct toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages

Stem Cells

Volumn 30, Issue 7, 2012, Pages 1486-1495

  Megías, Javier ^a   Yáñez, Alberto ^b   Moriano, Silvia ^b   O'Connor, José Enrique ^a   Gozalbo, Daniel ^b   Gil, María Luisa ^b  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Hematopoietic stem and progenitor cells; Macrophages; MyD88; Toll like receptors

Indexed keywords

CD11B ANTIGEN; CD19 ANTIGEN; CD45 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; LIPOPOLYSACCHARIDE; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; LYMPHOPOIESIS; MACROPHAGE; MOUSE; NONHUMAN; SPLEEN;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; MACROPHAGES; MICE; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

MURINAE; MUS;

EID: 84862865733     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1110     Document Type: Article

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