-
1
-
-
84888247676
-
Molecular and cellular endocrinology: Special issue on cytokine signaling
-
Groner B. Molecular and cellular endocrinology: special issue on cytokine signaling. Mol Cell Endocrinol 2014;382:551.
-
(2014)
Mol Cell Endocrinol
, vol.382
, pp. 551
-
-
Groner, B.1
-
2
-
-
84900524766
-
Determinants of the extent and duration of STAT3 signaling
-
Groner B. Determinants of the extent and duration of STAT3 signaling. JAKSTAT 2012;1:211-5.
-
(2012)
JAKSTAT
, vol.1
, pp. 211-215
-
-
Groner, B.1
-
3
-
-
0034722896
-
STAT proteins: Novel molecular targets for cancer drug discovery
-
Turkson J, Jove R. STAT proteins: novel molecular targets for cancer drug discovery. Oncogene 2000;19:6613-26.
-
(2000)
Oncogene
, vol.19
, pp. 6613-6626
-
-
Turkson, J.1
Jove, R.2
-
4
-
-
0036251154
-
Stat proteins and oncogenesis
-
Bromberg J. Stat proteins and oncogenesis. J Clin Invest 2002;109:1139-42.
-
(2002)
J Clin Invest
, vol.109
, pp. 1139-1142
-
-
Bromberg, J.1
-
5
-
-
84882586020
-
A membrane penetrating peptide aptamer inhibits STAT3 function and suppresses the growth of STAT3 addicted tumor cells
-
Borghouts C, Delis N, Brill B, Weiss A, Mack L, Lucks P, et al. A membrane penetrating peptide aptamer inhibits STAT3 function and suppresses the growth of STAT3 addicted tumor cells. JAKSTAT 2012;1:44-54.
-
(2012)
JAKSTAT
, vol.1
, pp. 44-54
-
-
Borghouts, C.1
Delis, N.2
Brill, B.3
Weiss, A.4
Mack, L.5
Lucks, P.6
-
6
-
-
5444237088
-
STAT proteins as novel targets for cancer drug discovery
-
Turkson J. STAT proteins as novel targets for cancer drug discovery. Expert Opin Ther Targets 2004;8:409-22.
-
(2004)
Expert Opin Ther Targets
, vol.8
, pp. 409-422
-
-
Turkson, J.1
-
7
-
-
33645514646
-
PIAS proteins and transcriptional regulation-more than just SUMO E3 ligases?
-
Sharrocks AD. PIAS proteins and transcriptional regulation-more than just SUMO E3 ligases? Genes Dev 2006;20:754-8.
-
(2006)
Genes Dev
, vol.20
, pp. 754-758
-
-
Sharrocks, A.D.1
-
8
-
-
32644459132
-
Regulation of cytokine signaling pathways by PIAS proteins
-
Shuai K. Regulation of cytokine signaling pathways by PIAS proteins. Cell Res 2006;16:196-202.
-
(2006)
Cell Res
, vol.16
, pp. 196-202
-
-
Shuai, K.1
-
9
-
-
0030725378
-
Specific inhibition of Stat3 signal transduction by PIAS3
-
Chung CD, Liao J, Liu B, Rao X, Jay P, Berta P, et al. Specific inhibition of Stat3 signal transduction by PIAS3. Science 1997;278:1803-5.
-
(1997)
Science
, vol.278
, pp. 1803-1805
-
-
Chung, C.D.1
Liao, J.2
Liu, B.3
Rao, X.4
Jay, P.5
Berta, P.6
-
10
-
-
72449201204
-
The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent
-
Dabir S, Kluge A, Dowlati A. The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependent. Mol Cancer Res 2009;7:1854-60.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1854-1860
-
-
Dabir, S.1
Kluge, A.2
Dowlati, A.3
-
11
-
-
68549117088
-
Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer
-
Kluge A, Dabir S, Kern J, Nethery D, Halmos B, Ma P, et al. Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer. Int J Cancer 2009;125:1728-34.
-
(2009)
Int J Cancer
, vol.125
, pp. 1728-1734
-
-
Kluge, A.1
Dabir, S.2
Kern, J.3
Nethery, D.4
Halmos, B.5
Ma, P.6
-
12
-
-
33749858519
-
Overexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivation
-
Ogata Y, Osaki T, Naka T, Iwahori K, Furukawa M, Nagatomo I, et al. Overexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivation. Neoplasia 2006;8:817-25.
-
(2006)
Neoplasia
, vol.8
, pp. 817-825
-
-
Ogata, Y.1
Osaki, T.2
Naka, T.3
Iwahori, K.4
Furukawa, M.5
Nagatomo, I.6
-
13
-
-
51049089073
-
Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: Implications for STAT-3 activation and gene expression
-
Brantley EC, Nabors LB, Gillespie GY, Choi YH, Palmer CA, Harrison K, et al. Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression. Clin Cancer Res 2008;14:4694-704.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 4694-4704
-
-
Brantley, E.C.1
Nabors, L.B.2
Gillespie, G.Y.3
Choi, Y.H.4
Palmer, C.A.5
Harrison, K.6
-
14
-
-
79957503772
-
Protein inhibitor of activated STAT3 expression in lung cancer
-
Kluge A, Dabir S, Vlassenbroeck I, Eisenberg R, Dowlati A. Protein inhibitor of activated STAT3 expression in lung cancer. Mol Oncol 2011;5:256-64.
-
(2011)
Mol Oncol
, vol.5
, pp. 256-264
-
-
Kluge, A.1
Dabir, S.2
Vlassenbroeck, I.3
Eisenberg, R.4
Dowlati, A.5
-
15
-
-
79960390329
-
Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors
-
Dabir S, Kluge A, Aziz MA, Houghton JA, Dowlati A. Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors. Cancer Biol Ther 2011;12:139-51.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 139-151
-
-
Dabir, S.1
Kluge, A.2
Aziz, M.A.3
Houghton, J.A.4
Dowlati, A.5
-
16
-
-
0035914305
-
Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2
-
Unkila M, McColl KS, Thomenius MJ, Heiskanen K, Distelhorst CW. Unreliability of the cytochrome c-enhanced green fluorescent fusion protein as a marker of cytochrome c release in cells that overexpress Bcl-2. J Biol Chem 2001;276:39132-7.
-
(2001)
J Biol Chem
, vol.276
, pp. 39132-39137
-
-
Unkila, M.1
McColl, K.S.2
Thomenius, M.J.3
Heiskanen, K.4
Distelhorst, C.W.5
-
17
-
-
77951164211
-
The intracellular delivery of a recombinant peptide derived from the acidic domain of PIAS3 inhibits STAT3 transactivation and induces tumor cell death
-
Borghouts C, Tittmann H, Delis N, Kirchenbauer M, Brill B, Groner B. The intracellular delivery of a recombinant peptide derived from the acidic domain of PIAS3 inhibits STAT3 transactivation and induces tumor cell death. Mol Cancer Res 2010;8:539-53.
-
(2010)
Mol Cancer Res
, vol.8
, pp. 539-553
-
-
Borghouts, C.1
Tittmann, H.2
Delis, N.3
Kirchenbauer, M.4
Brill, B.5
Groner, B.6
-
18
-
-
0000336139
-
Regression Models and Life-Tables
-
Cox DR. Regression Models and Life-Tables. J R Stat Soc Ser B-Stat Methodol 1972;34:187-220.
-
(1972)
J R Stat Soc Ser B-Stat Methodol
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
19
-
-
84859169877
-
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
-
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, et al. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012;483:603-7.
-
(2012)
Nature
, vol.483
, pp. 603-607
-
-
Barretina, J.1
Caponigro, G.2
Stransky, N.3
Venkatesan, K.4
Margolin, A.A.5
Kim, S.6
-
20
-
-
0036735386
-
Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma
-
Gordon GJ, Jensen RV, Hsiao LL, Gullans SR, Blumenstock JE, Ramaswamy S, et al. Translation of microarray data into clinically relevant cancer diagnostic tests using gene expression ratios in lung cancer and mesothelioma. Cancer Res 2002;62:4963-7.
-
(2002)
Cancer Res
, vol.62
, pp. 4963-4967
-
-
Gordon, G.J.1
Jensen, R.V.2
Hsiao, L.L.3
Gullans, S.R.4
Blumenstock, J.E.5
Ramaswamy, S.6
-
21
-
-
33845382806
-
Nonparametric Estimation from Incomplete Observations
-
Kaplan EL, Meier P. Nonparametric Estimation from Incomplete Observations. J Am Stat Assoc 1958;53:457-81.
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meier, P.2
-
23
-
-
51349137454
-
Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins
-
Kunnumakkara AB, Anand P, Aggarwal BB. Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins. Cancer Lett 2008;269:199-225.
-
(2008)
Cancer Lett
, vol.269
, pp. 199-225
-
-
Kunnumakkara, A.B.1
Anand, P.2
Aggarwal, B.B.3
-
24
-
-
77952077836
-
Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells
-
Saydmohammed M, Joseph D, Syed V. Curcumin suppresses constitutive activation of STAT-3 by up-regulating protein inhibitor of activated STAT-3 (PIAS-3) in ovarian and endometrial cancer cells. J Cell Biochem 2010;110:447-56.
-
(2010)
J Cell Biochem
, vol.110
, pp. 447-456
-
-
Saydmohammed, M.1
Joseph, D.2
Syed, V.3
-
25
-
-
34548710844
-
Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: Possible role for chemotherapeutic intervention
-
Achcar Rde O, Cagle PT, Jagirdar J. Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: possible role for chemotherapeutic intervention. Arch Pathol Lab Med 2007;131:1350-60.
-
(2007)
Arch Pathol Lab Med
, vol.131
, pp. 1350-1360
-
-
Achcar Rde, O.1
Cagle, P.T.2
Jagirdar, J.3
-
26
-
-
26444458845
-
Advances in malignant mesothelioma
-
Robinson BW, Lake RA. Advances in malignant mesothelioma. N Engl J Med 2005;353:1591-603.
-
(2005)
N Engl J Med
, vol.353
, pp. 1591-1603
-
-
Robinson, B.W.1
Lake, R.A.2
-
27
-
-
79955562300
-
Review on clinical trials of targeted treatments in malignant mesothelioma
-
Jakobsen JN, Sorensen JB. Review on clinical trials of targeted treatments in malignant mesothelioma. Cancer Chemother Pharmacol 2011;68:1-15.
-
(2011)
Cancer Chemother Pharmacol
, vol.68
, pp. 1-15
-
-
Jakobsen, J.N.1
Sorensen, J.B.2
-
28
-
-
72849130471
-
Molecular targets in malignant pleural mesothelioma treatment
-
Pasello G, Favaretto A. Molecular targets in malignant pleural mesothelioma treatment. Curr Drug Targets 2009;10:1235-44.
-
(2009)
Curr Drug Targets
, vol.10
, pp. 1235-1244
-
-
Pasello, G.1
Favaretto, A.2
-
29
-
-
79952269646
-
A phosphotyrosine proteomic screen identifies multiple tyrosine kinase signaling pathways aberrantly activated in malignant mesothelioma
-
Menges CW, Chen Y, Mossman BT, Chernoff J, Yeung AT, Testa JR. A phosphotyrosine proteomic screen identifies multiple tyrosine kinase signaling pathways aberrantly activated in malignant mesothelioma. Genes Cancer 2010;1:493-505.
-
(2010)
Genes Cancer
, vol.1
, pp. 493-505
-
-
Menges, C.W.1
Chen, Y.2
Mossman, B.T.3
Chernoff, J.4
Yeung, A.T.5
Testa, J.R.6
-
30
-
-
78650972238
-
Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma
-
Ou WB, Hubert C, Corson JM, Bueno R, Flynn DL, Sugarbaker DJ, et al. Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma. Neoplasia 2011;13:12-22.
-
(2011)
Neoplasia
, vol.13
, pp. 12-22
-
-
Ou, W.B.1
Hubert, C.2
Corson, J.M.3
Bueno, R.4
Flynn, D.L.5
Sugarbaker, D.J.6
-
31
-
-
16844372990
-
Gefitinib in patients with malignant mesothelioma: A phase II study by the Cancer and Leukemia Group B
-
Govindan R, Kratzke RA, Herndon JE II, Niehans GA, Vollmer R, Watson D, et al. Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. Clin Cancer Res 2005;11:2300-4.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2300-2304
-
-
Govindan, R.1
Kratzke, R.A.2
Herndon, J.E.3
Niehans, G.A.4
Vollmer, R.5
Watson, D.6
-
32
-
-
34347273808
-
Phase II study of erlotinib in patients with malignant pleural mesothelioma: A Southwest Oncology Group Study
-
Garland LL, Rankin C, Gandara DR, Rivkin SE, Scott KM, Nagle RB, et al. Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study. J Clin Oncol 2007;25:2406-13.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2406-2413
-
-
Garland, L.L.1
Rankin, C.2
Gandara, D.R.3
Rivkin, S.E.4
Scott, K.M.5
Nagle, R.B.6
-
33
-
-
84862193781
-
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
-
Zhang X, Yue P, Page BDG, Li T, Zhao W, Namanja AT, et al. Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci U S A 2012;109:9623-8.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 9623-9628
-
-
Zhang, X.1
Yue, P.2
Page, B.D.G.3
Li, T.4
Zhao, W.5
Namanja, A.T.6
-
34
-
-
84888438758
-
PIAS3 may represent a potential biomarker for diagnosis and therapeutic of human colorectal cancer
-
Li H, Gao H, Bijukchhe SM, Wang Y, Li T. PIAS3 may represent a potential biomarker for diagnosis and therapeutic of human colorectal cancer. Med Hypotheses 2013;81:1151-4.
-
(2013)
Med Hypotheses
, vol.81
, pp. 1151-1154
-
-
Li, H.1
Gao, H.2
Bijukchhe, S.M.3
Wang, Y.4
Li, T.5
-
35
-
-
80955179046
-
The expression of protein inhibitor of activated signal transducers and activators of transcription 3 in the evolutionary process of gastric cancer
-
Liu LM, Yan MG, Yang DH, Sun WW, Zhang JX. The expression of protein inhibitor of activated signal transducers and activators of transcription 3 in the evolutionary process of gastric cancer. Eur J Intern Med 2011;22:e31-5.
-
(2011)
Eur J Intern Med
, vol.22
, pp. e31-e35
-
-
Liu, L.M.1
Yan, M.G.2
Yang, D.H.3
Sun, W.W.4
Zhang, J.X.5
-
37
-
-
84866897574
-
Curcumin-cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer
-
Rocks N, Bekaert S, Coia I, Paulissen G, Gueders M, Evrard B, et al. Curcumin-cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer. Br J Cancer 2012;107:1083-92.
-
(2012)
Br J Cancer
, vol.107
, pp. 1083-1092
-
-
Rocks, N.1
Bekaert, S.2
Coia, I.3
Paulissen, G.4
Gueders, M.5
Evrard, B.6
-
38
-
-
40349111099
-
Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition
-
Borghouts C, Kunz C, Delis N, Groner B. Monomeric recombinant peptide aptamers are required for efficient intracellular uptake and target inhibition. Mol Cancer Res 2008;6:267-81.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 267-281
-
-
Borghouts, C.1
Kunz, C.2
Delis, N.3
Groner, B.4
-
39
-
-
84901304213
-
Base-catalyzed bicyclization of dialkyl glutaconates with cinnamoylacetamides: A synthetic strategy for isoquinolinedione derivatives
-
Li L, Zhao YL, Wang H, Li YJ, Xu X, Liu Q. Base-catalyzed bicyclization of dialkyl glutaconates with cinnamoylacetamides: a synthetic strategy for isoquinolinedione derivatives. Chem Commun 2014;50:6458-60.
-
(2014)
Chem Commun
, vol.50
, pp. 6458-6460
-
-
Li, L.1
Zhao, Y.L.2
Wang, H.3
Li, Y.J.4
Xu, X.5
Liu, Q.6
-
40
-
-
84893861378
-
Targeting survivin in cancer: Novel drug development approaches
-
Groner B, Weiss A. Targeting survivin in cancer: novel drug development approaches. Biodrugs 2014;28:27-39.
-
(2014)
Biodrugs
, vol.28
, pp. 27-39
-
-
Groner, B.1
Weiss, A.2
|