메뉴 건너뛰기




Volumn 10, Issue 12, 2009, Pages 1235-1244

Molecular targets in malignant pleural mesothelioma treatment

Author keywords

Angiogenesis; Apoptosis; Growth factor; Mesothelioma; Targeted therapies

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; 5,6 DIHYDROAZACITIDINE; ARENEGYR; BEVACIZUMAB; BORTEZOMIB; CARBOPLATIN; CEDIRANIB; CISPLATIN; DASATINIB; DOXORUBICIN; ERLOTINIB; GEFITINIB; GEMCITABINE; HISTONE DEACETYLASE INHIBITOR; IMATINIB; N (3 CHLOROPHENYL) 3 [3,5 DIMETHYL 4 (4 METHYL 1 PIPERAZINYLCARBONYL) 1H PYRROL 2 YLMETHYLENE] 2,3 DIHYDRO N METHYL 2 OXO 1H INDOLE 5 SULFONAMIDE; OCTREOTIDE; PEMETREXED; PLACEBO; PROTEASOME INHIBITOR; RANPIRNASE; RIBONUCLEASE INHIBITOR; SEMAXANIB; SOMATOMEDIN C DERIVATIVE; SORAFENIB; SUNITINIB; THALIDOMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANDETANIB; VASCULOTROPIN INHIBITOR; VATALANIB; VORINOSTAT;

EID: 72849130471     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/138945009789753200     Document Type: Review
Times cited : (24)

References (68)
  • 1
    • 33750057002 scopus 로고    scopus 로고
    • Biology and management of malignant pleural mesothelioma
    • DOI 10.1016/j.ejca.2006.07.011, PII S095980490600685X
    • Zucali PA, Giaccone G. Biology and management of malignant pleural mesothelioma. Eur J Cancer 2006; 42: 2706-2714 (Pubitemid 44584672)
    • (2006) European Journal of Cancer , vol.42 , Issue.16 , pp. 2706-2714
    • Zucali, P.A.1    Giaccone, G.2
  • 2
    • 56649103705 scopus 로고    scopus 로고
    • Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors
    • Weiner SJ, Neragi-Miandoab S. Pathogenesis of malignant pleural mesothelioma and the role of environmental and genetic factors. J Cancer Res Clin Oncol 2009; 135(1):15-27.
    • (2009) J Cancer Res Clin Oncol , vol.135 , Issue.1 , pp. 15-27
    • Weiner, S.J.1    Neragi-Miandoab, S.2
  • 3
    • 28444448395 scopus 로고    scopus 로고
    • Molecular biology pf malignant mesothelioma: A review
    • Pisick E, Salgia R. Molecular biology pf malignant mesothelioma: a review. Oncol Clin North Am 2005; 19(6): 997-1023.
    • (2005) Oncol Clin North Am , vol.19 , Issue.6 , pp. 997-1023
    • Pisick, E.1    Salgia, R.2
  • 5
    • 34547656272 scopus 로고    scopus 로고
    • Malignant mesothelioma: Global incidence and relationship with asbestos
    • DOI 10.2486/indhealth.45.379
    • Bianchi C, Bianchi T. Malignant mesothelioma: global incidence and relationship with asbestos. Ind Health 2007; 45(3): 379-387 (Pubitemid 47217199)
    • (2007) Industrial Health , vol.45 , Issue.3 , pp. 379-387
    • Bianchi, C.1    Bianchi, T.2
  • 6
    • 0032952875 scopus 로고    scopus 로고
    • Resection margins, extrapelural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: Results in 183 patients
    • Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, et al. Resection margins, extrapelural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. J Thorac Cardiovasc Surg 1999; 117: 54-63.
    • (1999) J Thorac Cardiovasc Surg , vol.117 , pp. 54-63
    • Sugarbaker, D.J.1    Flores, R.M.2    Jaklitsch, M.T.3    Richards, W.G.4    Strauss, G.M.5    Corson, J.M.6
  • 7
    • 4444316200 scopus 로고    scopus 로고
    • Neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma
    • Weder W, Kestenholz P, Taverna C, Bodis S, Lardinois D, Jerman M, et al. Neoadjuvant chemotherapy followed by extrapleural pneumonectomy in malignant pleural mesothelioma. J Clin Oncol 2004; 22(17): 3451-3457
    • (2004) J Clin Oncol , vol.22 , Issue.17 , pp. 3451-3457
    • Weder, W.1    Kestenholz, P.2    Taverna, C.3    Bodis, S.4    Lardinois, D.5    Jerman, M.6
  • 8
    • 34249665493 scopus 로고    scopus 로고
    • Induction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): Feasibility and results
    • DOI 10.1016/j.lungcan.2007.02.004, PII S0169500207001134
    • Rea F, Marulli G, Bortolotti L, Breda C, Favaretto AG, Loreggian L, et al. Induction chemotherapy, extrapleural pneumonectomy (EPP) and adjuvant hemi-thoracic radiation in malignant pleural mesothelioma (MPM): feasibility and results. Lung Cancer 2007; 57: 89-95. (Pubitemid 46843340)
    • (2007) Lung Cancer , vol.57 , Issue.1 , pp. 89-95
    • Rea, F.1    Marulli, G.2    Bortolotti, L.3    Breda, C.4    Favaretto, A.G.5    Loreggian, L.6    Sartori, F.7
  • 9
    • 63049128051 scopus 로고    scopus 로고
    • Trimodality therapy with induction chemotherapy followed by extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma
    • De Perrot M, Feld R, Cho BCJ, Bezjac A, Anraku M, Burkes R, et al. Trimodality therapy with induction chemotherapy followed by extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for malignant pleural mesothelioma. J Clin Oncol 2009; 27 (9): 1413-1418
    • (2009) J Clin Oncol , vol.27 , Issue.9 , pp. 1413-1418
    • De Perrot, M.1    Feld, R.2    Cho, B.C.J.3    Bezjac, A.4    Anraku, M.5    Burkes, R.6
  • 10
    • 67650002101 scopus 로고    scopus 로고
    • Multicenter Phase II Trial of Neoadjuvant Pemetrexed Plus Cisplatin Followed by Extrapleural Pneumonectomy and Radiation for Malignant Pleural Mesothelioma
    • Apr 13 [Epub ahead of print] DOI: 10.1200/JCO2008.20.3943
    • Krug LM, Pass HI, Rusch VW, Kindler HL, Sugarbaker DJ, Rosenzweig KE, et al. Multicenter Phase II Trial of Neoadjuvant Pemetrexed Plus Cisplatin Followed by Extrapleural Pneumonectomy and Radiation for Malignant Pleural Mesothelioma. J Clin Oncol 2009; Apr 13 [Epub ahead of print] DOI: 10.1200/JCO2008.20.3943.
    • (2009) J Clin Oncol
    • Krug, L.M.1    Pass, H.I.2    Rusch, V.W.3    Kindler, H.L.4    Sugarbaker, D.J.5    Rosenzweig, K.E.6
  • 11
    • 0041629528 scopus 로고    scopus 로고
    • Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma
    • Vogelzang NJ, Rusthoven JJ, Symanowski J, Denham C, Kaukel E, Ruffie P, et al. Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma. J Clin Oncol 2003; 21:2636-2644
    • (2003) J Clin Oncol , vol.21 , pp. 2636-2644
    • Vogelzang, N.J.1    Rusthoven, J.J.2    Symanowski, J.3    Denham, C.4    Kaukel, E.5    Ruffie, P.6
  • 14
    • 58149083475 scopus 로고    scopus 로고
    • Systemic treatments for mesothelioma: Standard and novel
    • Kindler HL. Systemic treatments for mesothelioma: standard and novel. Curr Treat Options Oncol 2008; 9(2-3): 171-179
    • (2008) Curr Treat Options Oncol , vol.9 , Issue.2-3 , pp. 171-179
    • Kindler, H.L.1
  • 16
    • 33745684876 scopus 로고    scopus 로고
    • Molecular pathways in malignant pleural mesothelioma
    • DOI 10.1016/j.canlet.2005.08.010, PII S0304383505007640
    • Whitson BA, Kratzke RA. Molecular pathways in malignant pleural mesothelioma. Cancer Lett 2006; 239: 183-189 (Pubitemid 43996826)
    • (2006) Cancer Letters , vol.239 , Issue.2 , pp. 183-189
    • Whitson, B.A.1    Kratzke, R.A.2
  • 17
    • 28444438883 scopus 로고    scopus 로고
    • Antiangiogenic therapies for mesothelioma
    • Dowell JE, Kindler HL. Antiangiogenic therapies for mesothelioma. Hematol Oncol Clin N Am 2005; 19: 1137-1145
    • (2005) Hematol Oncol Clin N Am , vol.19 , pp. 1137-1145
    • Dowell, J.E.1    Kindler, H.L.2
  • 18
    • 40749158416 scopus 로고    scopus 로고
    • Final analysis of a multicenter, double-blind, placebo-controlled randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma
    • abstract
    • Karrison T, Kindler HL, Gandara DR, Lu C, Guterz TL, Nichols K, et al. Final analysis of a multicenter, double-blind, placebo-controlled randomized phase II trial of gemcitabine/cisplatin plus bevacizumab or placebo in patients with malignant mesothelioma [abstract]. J Clin Oncol 2007; 25(18S):7526.
    • (2007) J Clin Oncol , vol.25 , Issue.18 S , pp. 7526
    • Karrison, T.1    Kindler, H.L.2    Gandara, D.R.3    Lu, C.4    Guterz, T.L.5    Nichols, K.6
  • 19
    • 72849133670 scopus 로고    scopus 로고
    • A multicenter phase II study of pemetrexed, cisplatin, and bevacizumab in patients with advanced malignant mesothelioma
    • Abstr. 7578
    • Dowell J, Taub R, Lan C, Xie Y, Dunphy F, Blake V, et al. A multicenter phase II study of pemetrexed, cisplatin, and bevacizumab in patients with advanced malignant mesothelioma. J Clin Oncol 2009; 27(15S): 401s (Abstr. 7578).
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Dowell, J.1    Taub, R.2    Lan, C.3    Xie, Y.4    Dunphy, F.5    Blake, V.6
  • 20
    • 65849296369 scopus 로고    scopus 로고
    • Growth inhibition by tyrosine kinase inhibitors in mesothelioma cell lines
    • Mar 23 [Epub ahead of print]
    • Nutt JE, O'Tool K, Gonzalez D, Lunec J. Growth inhibition by tyrosine kinase inhibitors in mesothelioma cell lines. Eur J Cancer 2009; Mar 23 [Epub ahead of print].
    • (2009) Eur J Cancer
    • Nutt, J.E.1    O'Tool, K.2    Gonzalez, D.3    Lunec, J.4
  • 21
    • 65349156374 scopus 로고    scopus 로고
    • Phase II study of sunitinib as second-line therapy in malignant pleural mesothelioma (MPM)
    • Abstract 8063
    • Nowak AK, Millward MJ, Francis R, van der Schaaff A, Musk AW, Byrne MJ. Phase II study of sunitinib as second-line therapy in malignant pleural mesothelioma (MPM). J Clin Oncol 2008; 26 (15S): Abstract 8063.
    • (2008) J Clin Oncol , vol.26 , Issue.15 S
    • Nowak, A.K.1    Millward, M.J.2    Francis, R.3    Van Der Schaaff, A.4    Musk, A.W.5    Byrne, M.J.6
  • 22
    • 72849108411 scopus 로고    scopus 로고
    • SWOG S0509: A phase II study of novel oral antiangiogenic agent AZD2171 (NSC-732208) in malignant pleural mesothelioma
    • Abstr. 7511
    • Garland LL, Chansky K, Wozniak A, Tsao A, Gadgeel S, Vershraegen C, et al. SWOG S0509: A phase II study of novel oral antiangiogenic agent AZD2171 (NSC-732208) in malignant pleural mesothelioma. J Clin Oncol 2009; 27(15S): 384s (Abstr. 7511).
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Garland, L.L.1    Chansky, K.2    Wozniak, A.3    Tsao, A.4    Gadgeel, S.5    Vershraegen, C.6
  • 24
    • 17044391939 scopus 로고    scopus 로고
    • Thalidomide alone or in combination with cisplatin/gemcitabine in malignant pleural mesothelioma: Interim results from two parallel non randomized phase II studies
    • abstract
    • Pavlakis N, Abraham R, Harvie R, Brock C, Bell D, Boyle F, et al. Thalidomide alone or in combination with cisplatin/gemcitabine in malignant pleural mesothelioma: interim results from two parallel non randomized phase II studies [abstract]. Lung Cancer 2003; 41(2S): S11.
    • (2003) Lung Cancer , vol.41 , Issue.2 S
    • Pavlakis, N.1    Abraham, R.2    Harvie, R.3    Brock, C.4    Bell, D.5    Boyle, F.6
  • 27
    • 24744463358 scopus 로고    scopus 로고
    • Limited efficacy of imatinib mesylate in malignant mesothelioma: A phase II trial
    • DOI 10.1016/j.lungcan.2005.04.010, PII S0169500205001959
    • Mathy A, Baas P, Dalesio O, van Zandwijk N. Limited efficacy of imatinib mesylate in malignant mesotelioma: a phase II trial. Lung Cancer 2005; 50(1): 83-86 (Pubitemid 41297473)
    • (2005) Lung Cancer , vol.50 , Issue.1 , pp. 83-86
    • Mathy, A.1    Baas, P.2    Dalesio, O.3    Van Zandwijk, N.4
  • 28
    • 34547765871 scopus 로고    scopus 로고
    • Preliminary data suggestive of a novel translational approach to mesothelioma treatment: Imatinib mesylate with gemcitabine or pemetrexed
    • DOI 10.1136/thx.2006.069872
    • Bertino P, Porta C, Barbone D, Germano S, Busacca S, Pinato S, et al. Preliminary data suggestive of a novel translational approach to mesothelioma treatment: imatinib mesylate with gemcitabine or pemetrexed. Thorax 2007; 62(8):690-695 (Pubitemid 47235011)
    • (2007) Thorax , vol.62 , Issue.8 , pp. 690-695
    • Bertino, P.1    Porta, C.2    Barbone, D.3    Germano, S.4    Busacca, S.5    Pinato, S.6    Tassi, G.7    Favoni, R.8    Gaudino, G.9    Mutti, L.10
  • 29
    • 38949184992 scopus 로고    scopus 로고
    • Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts
    • Bertino P, Piccardi F, Porta C, Favoni R, Cilli M, Mutti L, et al. Imatinib mesylate enhances therapeutic effects of gemcitabine in human malignant mesothelioma xenografts. Clin Cancer Res 2008; 14(2):541-548
    • (2008) Clin Cancer Res , vol.14 , Issue.2 , pp. 541-548
    • Bertino, P.1    Piccardi, F.2    Porta, C.3    Favoni, R.4    Cilli, M.5    Mutti, L.6
  • 30
    • 34447316429 scopus 로고    scopus 로고
    • Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion
    • Tsao AS, He D, Saigal B, Liu S, Lee JJ, Bakkannagari S, et al. Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion. Mol Cancer Ther 2007; 6(7): 1962-1972
    • (2007) Mol Cancer Ther , vol.6 , Issue.7 , pp. 1962-1972
    • Tsao, A.S.1    He, D.2    Saigal, B.3    Liu, S.4    Lee, J.J.5    Bakkannagari, S.6
  • 31
    • 62549100461 scopus 로고    scopus 로고
    • Neoadjuvant and intrapleural therapies for malignant pleural mesothelioma
    • Tsao AS, Mehran R, Roth JA. Neoadjuvant and intrapleural therapies for malignant pleural mesothelioma. Clin Lung Cancer 2009; 10(1): 36-41.
    • (2009) Clin Lung Cancer , vol.10 , Issue.1 , pp. 36-41
    • Tsao, A.S.1    Mehran, R.2    Roth, J.A.3
  • 32
    • 72849106482 scopus 로고    scopus 로고
    • Phase I trial of neoadjuvant dasatinib in patients with resectable malignant pleural mesothelioma
    • Abstr. 7580
    • Mehran R, Gil J, Rice D, Swisher S, Lee JJ, Lippman S, et al. Phase I trial of neoadjuvant dasatinib in patients with resectable malignant pleural mesothelioma. J Clin Oncol 2009; 27(15S): 402s (Abstr. 7580).
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Mehran, R.1    Gil, J.2    Rice, D.3    Swisher, S.4    Lee, J.J.5    Lippman, S.6
  • 33
    • 58049192366 scopus 로고    scopus 로고
    • MET as a target for treatment of chest tumours
    • Cipriani NA, Abidoy OO, Vokes E, Salgia R. MET as a target for treatment of chest tumours. Lung Cancer 2009; 63(2): 169-179
    • (2009) Lung Cancer , vol.63 , Issue.2 , pp. 169-179
    • Cipriani, N.A.1    Abidoy, O.O.2    Vokes, E.3    Salgia, R.4
  • 34
    • 0141481285 scopus 로고    scopus 로고
    • A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase
    • Sattler M, Pride YB, Ma P, Gramlich JL, Chu SC, Quinnan LA, et al. A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase. Cancer Res 2003; 63(17): 5462-5469
    • (2003) Cancer Res , vol.63 , Issue.17 , pp. 5462-5469
    • Sattler, M.1    Pride, Y.B.2    Ma, P.3    Gramlich, J.L.4    Chu, S.C.5    Quinnan, L.A.6
  • 36
    • 72849113493 scopus 로고    scopus 로고
    • Phase II clinical trial of NGR-hTNF, a novel vascular targeting agent (VTA), as second-line therapy in malignant pleural mesothelioma (MPM)
    • abstract
    • Ceresoli GL, Gregorc V, Zucali PA, Noberasco C, Bajetta E, Santoro A et al. Phase II clinical trial of NGR-hTNF, a novel vascular targeting agent (VTA), as second-line therapy in malignant pleural mesothelioma (MPM). Ann Oncol 2008; 19(8S): abstract 334 p.
    • (2008) Ann Oncol , vol.19 , Issue.8 S
    • Ceresoli, G.L.1    Gregorc, V.2    Zucali, P.A.3    Noberasco, C.4    Bajetta, E.5    Santoro, A.6
  • 38
    • 31344449869 scopus 로고    scopus 로고
    • EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinicopathological correlations
    • Destro A, Ceresoli GL, Falleni L, Zucali PA, Morenghi E, Bianchi P, et al. EGFR overexpression in malignant pleural mesothelioma. An immunohistochemical and molecular study with clinicopathological correlations. Lung Cancer 2006; 51: 207-215
    • (2006) Lung Cancer , vol.51 , pp. 207-215
    • Destro, A.1    Ceresoli, G.L.2    Falleni, L.3    Zucali, P.A.4    Morenghi, E.5    Bianchi, P.6
  • 39
    • 33750313674 scopus 로고    scopus 로고
    • EGFR expression and associations with outcome and clinicopathological variables in malignant pleural mesothelioma
    • Edwards GJ, Swinson DE, Jones JL, Waller DA, O'Byrne KJ. EGFR expression and associations with outcome and clinicopathological variables in malignant pleural mesothelioma. Lung Cancer 2006; 54: 399-407.
    • (2006) Lung Cancer , vol.54 , pp. 399-407
    • Edwards, G.J.1    Swinson, D.E.2    Jones, J.L.3    Waller, D.A.4    O'Byrne, K.J.5
  • 40
    • 50249128105 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma
    • Okuda K, Sasaki H, Kawano O, Yukiue H, Yokoyama T, Yano M, et al. Epidermal growth factor receptor gene mutation, amplification and protein expression in malignant pleural mesothelioma. J Cancer Res Clin Oncol 2008; 134: 1105-1111
    • (2008) J Cancer Res Clin Oncol , vol.134 , pp. 1105-1111
    • Okuda, K.1    Sasaki, H.2    Kawano, O.3    Yukiue, H.4    Yokoyama, T.5    Yano, M.6
  • 41
    • 0037105665 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma
    • Janne PA, Taffaro ML, Salgia R, Johnson BE. Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma. Cancer Res 2002; 62: 5242-5247 (Pubitemid 35024597)
    • (2002) Cancer Research , vol.62 , Issue.18 , pp. 5242-5247
    • Janne, P.A.1    Taffaro, M.L.2    Salgia, R.3    Johnson, B.E.4
  • 42
    • 16844372990 scopus 로고    scopus 로고
    • Gefitinib in patients with malignant mesothelioma: A phase II study by the Cancer and Leukemia Group B
    • Govindan R, Kratzke RA, Herndon JE 2nd, Niehans GA, Vollmer R, Watson D et al. Gefitinib in patients with malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B. Clin Cancer Res 2005; 11: 2300-2304
    • (2005) Clin Cancer Res , vol.11 , pp. 2300-2304
    • Govindan, R.1    Kratzke, R.A.2    Herndon II, J.E.3    Niehans, G.A.4    Vollmer, R.5    Watson, D.6
  • 43
    • 34347273808 scopus 로고    scopus 로고
    • Phase II study of erlotinib in patients with malignant pleural mesothelioma: A Southwest Oncology Group Study
    • Garland LL, Rankin C, Gandara DR, Rivkin SE, Scott KM, Nagle RB, et al. Phase II study of erlotinib in patients with malignant pleural mesothelioma: a Southwest Oncology Group Study. J Clin Oncol 2007; 25(17): 2406-2413
    • (2007) J Clin Oncol , vol.25 , Issue.17 , pp. 2406-2413
    • Garland, L.L.1    Rankin, C.2    Gandara, D.R.3    Rivkin, S.E.4    Scott, K.M.5    Nagle, R.B.6
  • 44
    • 67650132370 scopus 로고    scopus 로고
    • Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells
    • Apr 20 [epub ahead of print]
    • Kawaguchi K, Murakami H, Taniguchi T, Fujii M, Kawata S, Fukui T, et al. Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells. Carcinogenesis 2009; Apr 20 [epub ahead of print].
    • (2009) Carcinogenesis
    • Kawaguchi, K.1    Murakami, H.2    Taniguchi, T.3    Fujii, M.4    Kawata, S.5    Fukui, T.6
  • 45
    • 50249155473 scopus 로고    scopus 로고
    • Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma
    • Jackman DM, Kindler HL, Yeap BY, Fidias P, Salgia R, Lucca J, et al. Erlotinib plus bevacizumab in previously treated patients with malignant pleural mesothelioma. Cancer 2008; 113: 808-814
    • (2008) Cancer , vol.113 , pp. 808-814
    • Jackman, D.M.1    Kindler, H.L.2    Yeap, B.Y.3    Fidias, P.4    Salgia, R.5    Lucca, J.6
  • 46
    • 43449119495 scopus 로고    scopus 로고
    • Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement
    • Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, et al. Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement. Cancer Lett 2008; 265: 55-66.
    • (2008) Cancer Lett , vol.265 , pp. 55-66
    • Ogino, H.1    Yano, S.2    Kakiuchi, S.3    Yamada, T.4    Ikuta, K.5    Nakataki, E.6
  • 47
    • 63449104490 scopus 로고    scopus 로고
    • Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines
    • Kai K, D'Costa S, Sills RC, Kim Yongbaek. Inhibition of the insulin-like growth factor 1 receptor pathway enhances the antitumor effect of cisplatin in human malignant mesothelioma cell lines. Cancer Lett 2009; 278: 49-55.
    • (2009) Cancer Lett , vol.278 , pp. 49-55
    • Kai, K.1    D'Costa, S.2    Sills, R.C.3    Yongbaek, K.4
  • 48
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 49
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis: A link between cancer genetics and chemotherapy
    • Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: a link between cancer genetics and chemotherapy. Cell 2002; 108: 153-164
    • (2002) Cell , vol.108 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 50
    • 2542443539 scopus 로고    scopus 로고
    • Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: Opportunities for effective drug development
    • Fennell DA, Rudd RM. Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development. Lancet Oncol 2004; 5(6): 354-362
    • (2004) Lancet Oncol , vol.5 , Issue.6 , pp. 354-362
    • Fennell, D.A.1    Rudd, R.M.2
  • 51
    • 34247146844 scopus 로고    scopus 로고
    • Update on the molecular biology of malignant mesothelioma
    • DOI 10.1002/cncr.22552
    • Lee AY, Raz DJ, He B, Jablons DM. Update on the molecular biology of malignant mesothelioma. Cancer 2007; 109(8):1454-1461 (Pubitemid 46595678)
    • (2007) Cancer , vol.109 , Issue.8 , pp. 1454-1461
    • Lee, A.Y.1    Ras, D.J.2    He, B.3    Jablons, D.M.4
  • 52
    • 0036837992 scopus 로고    scopus 로고
    • INK4a expression in malignant mesothelioma by methylation
    • DOI 10.1016/S0169-5002(02)00178-2, PII S0169500202001782
    • Wong L, Zhou J, Anderson D, Kratzke RA. Inactivation of p16INK4a expression in malignant mesothelioma methylation. Lung Cancer 2002; 38:131-136 (Pubitemid 35154376)
    • (2002) Lung Cancer , vol.38 , Issue.2 , pp. 131-136
    • Wong, L.1    Zhou, J.2    Anderson, D.3    Kratzke, R.A.4
  • 53
    • 0031000513 scopus 로고    scopus 로고
    • Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B
    • Vogelzang NJ, Herndon JE 2nd, Cirrincione C, Harmon DC, Antman KH, Corson JM, et al. Dihydro-5-azacytidine in malignant mesothelioma. A phase II trial demonstrating activity accompanied by cardiac toxicity. Cancer and Leukemia Group B. Cancer 1997; 79(11):2237-2242
    • (1997) Cancer , vol.79 , Issue.11 , pp. 2237-2242
    • Vogelzang, N.J.1    Herndon II, J.E.2    Cirrincione, C.3    Harmon, D.C.4    Antman, K.H.5    Corson, J.M.6
  • 54
    • 0032522949 scopus 로고    scopus 로고
    • Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma: A phase II study by the Cancer and Leukemia Group B
    • Samuels BL, Herndon JE 2nd, Harmon DC, Carey R, Aisner J, Corson JM, et al. Dihydro-5-azacytidine and cisplatin in the treatment of malignant mesothelioma : a phase II study by the Cancer and Leukemia Group B. Cancer 1998; 82(8): 1578-1584
    • (1998) Cancer , vol.82 , Issue.8 , pp. 1578-1584
    • Samuels, B.L.1    Herndon II, J.E.2    Harmon, D.C.3    Carey, R.4    Aisner, J.5    Corson, J.M.6
  • 55
    • 41749102001 scopus 로고    scopus 로고
    • Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a
    • Kratzke RA, Wang X, Wong L, Kratzke MG, Green MR, Vokes EE, et al. Response to the methylation inhibitor dihydro-5-azacytidine in mesothelioma is not associated with methylation of p16INK4a . J Thorac Oncol 2008; 3(4): 417-421
    • (2008) J Thorac Oncol , vol.3 , Issue.4 , pp. 417-421
    • Kratzke, R.A.1    Wang, X.2    Wong, L.3    Kratzke, M.G.4    Green, M.R.5    Vokes, E.E.6
  • 56
    • 67349285731 scopus 로고    scopus 로고
    • Enhancing the apoptotic and therapeutic effects of HDAC inhibitors
    • Apr 7 [epub ahead of print]
    • Frew AJ, Johnstone RW, Bolden JE. Enhancing the apoptotic and therapeutic effects of HDAC inhibitors. Cancer Lett 2009; Apr 7 [epub ahead of print]
    • (2009) Cancer Lett
    • Frew, A.J.1    Johnstone, R.W.2    Bolden, J.E.3
  • 57
    • 33244458274 scopus 로고    scopus 로고
    • Potential role of histone deacetylase inhibitors in mesothelioma: Clinical experience with suberoylanilide hydroxamic acid
    • Krug LM, Curley T, Schwartz L, Richardson S, Marks P, Chiao J, et al. Potential role of histone deacetylase inhibitors in mesothelioma: clinical experience with suberoylanilide hydroxamic acid. Clin Lung Cancer 2006; 7: 257-261 (Pubitemid 43280028)
    • (2006) Clinical Lung Cancer , vol.7 , Issue.4 , pp. 257-261
    • Krug, L.M.1    Curley, T.2    Schwartz, L.3    Richardson, S.4    Marks, P.5    Chiao, J.6    Kelly, W.K.7
  • 58
    • 65249096105 scopus 로고    scopus 로고
    • Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma
    • Vandermeers F, Hubert P, Delvenne P, Mascaux C, Grigoriu B, Burny A, et al. Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma. Clin Cancer Res 2009; 15(8): 2818-2828
    • (2009) Clin Cancer Res , vol.15 , Issue.8 , pp. 2818-2828
    • Vandermeers, F.1    Hubert, P.2    Delvenne, P.3    Mascaux, C.4    Grigoriu, B.5    Burny, A.6
  • 59
    • 33644832724 scopus 로고    scopus 로고
    • Targeted induction of apoptosis in cancer management: The emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents
    • Rowinsky EK. Targeted induction of apoptosis in cancer management: the emerging role of tumor necrosis factor-related apoptosis-inducing ligand receptor activating agents. J Clin Oncol 2005; 23(36): 9394-9407
    • (2005) J Clin Oncol , vol.23 , Issue.36 , pp. 9394-9407
    • Rowinsky, E.K.1
  • 60
    • 37249013515 scopus 로고    scopus 로고
    • Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin
    • DOI 10.1186/1476-4598-6-66
    • Belyanskaya LL, Marti TM, Hopkins-Donaldson S, Kurtz S, Felley-Bosco E, Stahel R. Human agonistic TRAIL receptor antibodies Mapatumumab and Lexatumumab induce apoptosis in malignant mesothelioma and act synergistically with cisplatin. Mol Cancer 2007; 6:66. (Pubitemid 350278695)
    • (2007) Molecular Cancer , vol.6 , pp. 66
    • Belyanskaya, L.L.1    Marti, T.M.2    Hopkins-Donaldson, S.3    Kurtz, S.4    Felley-Bosco, E.5    Stahel, R.A.6
  • 61
    • 44349114451 scopus 로고    scopus 로고
    • Molecular targets and targeted therapies for malignant mesothelioma
    • DOI 10.2174/092986708783955446
    • Palumbo C, Bei R, Procopio A, Modesti A. Molecular targets and targeted terapies for malignant mesotelioma. Curr Med Chem 2008; 15(9): 855-867 (Pubitemid 351736408)
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.9 , pp. 855-867
    • Palumbo, C.1    Bei, R.2    Procopio, A.3    Modesti, A.4
  • 62
    • 67349127898 scopus 로고    scopus 로고
    • The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents
    • Apr 21 [Epub ahead of print]
    • Sankhala K, Mita A, Kelly K, Mahalingam D, Giles F, Mita M. The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. Target Oncol 2009; Apr 21 [Epub ahead of print].
    • (2009) Target Oncol
    • Sankhala, K.1    Mita, A.2    Kelly, K.3    Mahalingam, D.4    Giles, F.5    Mita, M.6
  • 64
    • 69249211723 scopus 로고    scopus 로고
    • Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells
    • Yuan B-Z, Chapman JA, and Reynolds SH. Proteasome inhibitor MG132 induces apoptosis and inhibits invasion of human malignant pleural mesothelioma cells. Translat Oncol 2008; 1(3): 129-140
    • (2008) Translat Oncol , vol.1 , Issue.3 , pp. 129-140
    • Yuan, B.-Z.1    Chapman, J.A.2    Reynolds, S.H.3
  • 65
    • 77649132326 scopus 로고    scopus 로고
    • Randomized, multicenter phase III study of ranpirnase plus doxorubicin versus doxorubicin in patients with unresectable malignant mesothelioma
    • Abstr.7507
    • Reck M, Krzakowski M, Jassem J, Eschbach C, Kozielski J, Costanzi JJ, et al. Randomized, multicenter phase III study of ranpirnase plus doxorubicin versus doxorubicin in patients with unresectable malignant mesothelioma. J Clin Oncol 2009; 27 (15S): 383s (Abstr.7507).
    • (2009) J Clin Oncol , vol.27 , Issue.15 S
    • Reck, M.1    Krzakowski, M.2    Jassem, J.3    Eschbach, C.4    Kozielski, J.5    Costanzi, J.J.6
  • 66
    • 33846391728 scopus 로고    scopus 로고
    • Vatalanib for patients with previously untreated advanced malignant mesothelioma: A phase II study by the Cancer and Leukemia Group B (CALGB 30107)
    • Abstract 7081
    • Jahan TM, Gu L, Wang X, Kratzke RA, Dudek AZ, Green MR, et al. Vatalanib for patients with previously untreated advanced malignant mesothelioma: a phase II study by the Cancer and Leukemia Group B (CALGB 30107). J Clin Oncol 2006; 24(18S): Abstract 7081.
    • (2006) J Clin Oncol , vol.24 , Issue.18 S
    • Jahan, T.M.1    Gu, L.2    Wang, X.3    Kratzke, R.A.4    Dudek, A.Z.5    Green, M.R.6
  • 68
    • 58149092517 scopus 로고    scopus 로고
    • Sorafenib in malignant mesothelioma: A phase II trial of the Cancer and Leukemia Group B (CALGB 30307)
    • Abstract 7707
    • Janne PA, Wang XF, Krug LM, Hodgson L, Vokes EE, Kindler HL. Sorafenib in malignant mesothelioma: a phase II trial of the Cancer and Leukemia Group B (CALGB 30307). J Clin Oncol 2007; 25 (17S): Abstract 7707.
    • (2007) J Clin Oncol , vol.25 , Issue.17 S
    • Janne, P.A.1    Wang, X.F.2    Krug, L.M.3    Hodgson, L.4    Vokes, E.E.5    Kindler, H.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.