Synthesis, in silico preclinical evaluation, antidepressant potential of 5-substituted phenyl-3-(thiophen-2-yl)-4,5-dihydro-1h-pyrazole-1-carboxamides

Biomedicine and Aging Pathology

Volumn 4, Issue 4, 2014, Pages 327-333

  Mathew, Bijo ^a   Suresh, Jerad ^b   Anbazhagan, S ^c  

^a Department of Pharmaceutical Chemistry   (India)

^b MADRAS MEDICAL COLLEGE   (India)

^c Surya School of Pharmacy   (India)

Author keywords

2 Acetyl thiophene; Antidepressant; In silico toxicity prediction; Pyrazolines

Indexed keywords

5 (3 NITROPHENYL) 3 (THIOPHEN 2 YL) 4,5 DIHYDRO 1H PYROAZOLE 1 CARBOXAMIDE; AMIDE; ANTIDEPRESSANT AGENT; CHLORINE; IMIPRAMINE; PYRAZOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDEPRESSANT ACTIVITY; ARTICLE; BLOOD BRAIN BARRIER; CARBON NUCLEAR MAGNETIC RESONANCE; COMPUTER MODEL; CONTROLLED STUDY; DRUG ABSORPTION; FORCED SWIM TEST; HUMAN; INFRARED RADIATION; MOUSE; NEUROTOXICITY; NONHUMAN; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ROTAROD TEST; SYNTHESIS; TAIL SUSPENSION TEST;

EID: 84908269895     PISSN: 22105220     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomag.2014.08.002     Document Type: Article

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