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Volumn 21, Issue 4, 2011, Pages 1253-1256
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Discovery of new anti-depressants from structurally novel 5-HT3 receptor antagonists: Design, synthesis and pharmacological evaluation of 3-ethoxyquinoxalin-2-carboxamides
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Author keywords
5 HT3 receptor antagonists; Anti depressants; Forced swim test; Quinoxalines; Serotonin; Spontaneous locomotor activity
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Indexed keywords
(3 ETHOXYQUINOXALIN 2 YL)(4 METHYLPIPERAZIN 1 YL)METHANONE;
1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE;
1 HYDROXYBENZOTRIAZOLE;
3 ETHOXYQUINOXALIN 2 CARBOXAMIDE DERIVATIVE;
ANTIDEPRESSANT AGENT;
BENZOTRIAZOLE DERIVATIVE;
ONDANSETRON;
QUINOXALINE DERIVATIVE;
SEROTONIN 3 ANTAGONIST;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL TISSUE;
ARTICLE;
DOSE RESPONSE;
DRUG ACTIVITY;
DRUG DESIGN;
DRUG STRUCTURE;
DRUG SYNTHESIS;
EXPERIMENTAL GUINEA PIG;
FORCED SWIMMING TEST;
LOCOMOTION;
MALE;
MOUSE;
MYENTERIC PLEXUS;
NONHUMAN;
PHARMACOPHORE;
AMIDES;
ANIMALS;
ANTIDEPRESSIVE AGENTS;
DRUG DESIGN;
DRUG EVALUATION, PRECLINICAL;
GUINEA PIGS;
MYENTERIC PLEXUS;
PIPERAZINES;
QUINOXALINES;
RECEPTORS, SEROTONIN, 5-HT3;
SEROTONIN 5-HT3 RECEPTOR ANTAGONISTS;
STRUCTURE-ACTIVITY RELATIONSHIP;
CAVIA;
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EID: 79851512235
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2010.12.064 Document Type: Article |
Times cited : (29)
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References (28)
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