메뉴 건너뛰기




Volumn 49, Issue 9, 2014, Pages 1314-1323

Novel risk factors for lymph node metastasis in early invasive colorectal cancer: A multi-institution pathology review

(18)  Ueno, Hideki a   Hase, Kazuo a   Hashiguchi, Yojiro b   Shimazaki, Hideyuki a   Yoshii, Shinji c   Kudo, Shin ei d   Tanaka, Masafumi e   Akagi, Yoshito f   Suto, Takeshi g   Nagata, Shinji h   Matsuda, Keiji b   Komori, Koji i   Yoshimatsu, Kazuhiko j   Tomita, Yasuhiko k   Yokoyama, Shozo l   Shinto, Eiji a   Nakamura, Takahiro a   Sugihara, Kenichi m  


Author keywords

Endoscopic excision; Lymph node metastases; Poorly differentiated clusters; T1 colorectal cancer; Tumor budding

Indexed keywords

MUCIN;

EID: 84908263241     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-013-0881-3     Document Type: Review
Times cited : (96)

References (55)
  • 1
    • 84856032575 scopus 로고    scopus 로고
    • Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: A systematic review
    • Repici A, Hassan C, Pessoa DDP, Pagano N, Arezzo A, Zullo A, et al. Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy. 2012;44: 137-47.
    • (2012) Endoscopy , vol.44 , pp. 137-147
    • Repici, A.1    Hassan, C.2    Pessoa, D.D.P.3    Pagano, N.4    Arezzo, A.5    Zullo, A.6
  • 2
    • 84868206173 scopus 로고    scopus 로고
    • Comparison of endoscopic submucosal dissection with laparoscopic-assisted colorectal surgery for earlystage colorectal cancer: A retrospective analysis
    • Kiriyama S, Saito Y, Yamamoto S, Soetikno R, Matsuda T, Nakajima T, et al. Comparison of endoscopic submucosal dissection with laparoscopic-assisted colorectal surgery for earlystage colorectal cancer: a retrospective analysis. Endoscopy. 2012;44:1024-30.
    • (2012) Endoscopy , vol.44 , pp. 1024-1030
    • Kiriyama, S.1    Saito, Y.2    Yamamoto, S.3    Soetikno, R.4    Matsuda, T.5    Nakajima, T.6
  • 3
    • 84893829896 scopus 로고    scopus 로고
    • Endoscopic submucosal dissection for colorectal tumors-1000 colorectal ESD cases one specialized institute's experiences
    • (Epub ahead of print)
    • Lee EJ, Lee JB, Lee SH, Kim DS, Lee DH, Lee DS, et al. Endoscopic submucosal dissection for colorectal tumors-1000 colorectal ESD cases: one specialized institute's experiences. Surg Endosc 2012 (Epub ahead of print).
    • (2012) Surg Endosc
    • Lee, E.J.1    Lee, J.B.2    Lee, S.H.3    Kim, D.S.4    Lee, D.H.5    Lee, D.S.6
  • 4
    • 0021059477 scopus 로고
    • Surgical pathology of endoscopically removed malignant polyps of the colon and rectum
    • Cooper HS. Surgical pathology of endoscopically removed malignant polyps of the colon and rectum. Am J Surg Pathol. 1983;7:613-23.
    • (1983) Am J Surg Pathol , vol.7 , pp. 613-623
    • Cooper, H.S.1
  • 5
    • 0021369278 scopus 로고
    • Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy
    • Morson BC, Whiteway JE, Jones EA, Macrae FA, Williams CB. Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy. Gut. 1984;25:437-44.
    • (1984) Gut , vol.25 , pp. 437-444
    • Morson, B.C.1    Whiteway, J.E.2    Jones, E.A.3    Macrae, F.A.4    Williams, C.B.5
  • 6
    • 0019867466 scopus 로고
    • Endoscopic polypectomy: Inadequate treatment for invasive colorectal carcinoma
    • Colacchio TA, Forde KA, Scantlebury VP. Endoscopic polypectomy: inadequate treatment for invasive colorectal carcinoma. Ann Surg. 1981;194:704-7.
    • (1981) Ann Surg , vol.194 , pp. 704-707
    • Colacchio, T.A.1    Forde, K.A.2    Scantlebury, V.P.3
  • 7
    • 0024376489 scopus 로고
    • Management of patients with invasive carcinoma removed by colonoscopic polypectomy
    • Sugihara K, Muto T, Morioka Y. Management of patients with invasive carcinoma removed by colonoscopic polypectomy. Dis Colon Rectum. 1989;32:829-34.
    • (1989) Dis Colon Rectum , vol.32 , pp. 829-834
    • Sugihara, K.1    Muto, T.2    Morioka, Y.3
  • 8
    • 0022647237 scopus 로고
    • When is endoscopic polypectomy adequate therapy for colonic polyps containing invasive carcinoma?
    • Cranley JP, Petras RE, Carey WD, Paradis K, Sivak MV. When is endoscopic polypectomy adequate therapy for colonic polyps containing invasive carcinoma? Gastroenterology. 1986;91: 419-27.
    • (1986) Gastroenterology , vol.91 , pp. 419-427
    • Cranley, J.P.1    Petras, R.E.2    Carey, W.D.3    Paradis, K.4    Sivak, M.V.5
  • 9
    • 0024416097 scopus 로고
    • Colorectal adenomas containing invasive carcinoma: Pathologic assessment of lymph node metastatic potential
    • Coverlizza S, Risio M, Ferrari A, Fenoglio-Preiser CM, Rossini FP. Colorectal adenomas containing invasive carcinoma: pathologic assessment of lymph node metastatic potential. Cancer. 1989;64:1937-47.
    • (1989) Cancer , vol.64 , pp. 1937-1947
    • Coverlizza, S.1    Risio, M.2    Ferrari, A.3    Fenoglio-Preiser, C.M.4    Rossini, F.P.5
  • 10
    • 0024421044 scopus 로고
    • Significance of venous and lymphatic invasion in malignant polyps of the colon and rectum
    • Muller S, Chesner IM, Egan MJ, Rowlands DC, Collard MJ, Swarbrick ET, et al. Significance of venous and lymphatic invasion in malignant polyps of the colon and rectum. Gut. 1989;30:1385-91.
    • (1989) Gut , vol.30 , pp. 1385-1391
    • Muller, S.1    Chesner, I.M.2    Egan, M.J.3    Rowlands, D.C.4    Collard, M.J.5    Swarbrick, E.T.6
  • 11
    • 81055135326 scopus 로고    scopus 로고
    • (version 4. 2013). Accessed Dec 3 2012
    • National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology-colon cancer (version 4. 2013). 2012. http://www.nccn.org/professionals/physician_gls/pdf/colon.pdf. Accessed Dec 3 2012.
    • (2012) NCCN clinical practice guidelines in oncology-colon cancer
  • 14
    • 22744449900 scopus 로고    scopus 로고
    • Histologic risk factors and clinical outcome in colorectal malignant polyp: A pooled-data analysis
    • Hassan C, Zullo A, Risio M, Rossini FP, Morini S. Histologic risk factors and clinical outcome in colorectal malignant polyp: a pooled-data analysis. Dis Colon Rectum. 2005;48:1588-96.
    • (2005) Dis Colon Rectum , vol.48 , pp. 1588-1596
    • Hassan, C.1    Zullo, A.2    Risio, M.3    Rossini, F.P.4    Morini, S.5
  • 15
    • 0028879456 scopus 로고
    • Management and outcome of patients with invasive carcinoma arising in colorectal polyps
    • Volk EE, Goldblum JR, Petras RE, Carey WD, Fazio VW. Management and outcome of patients with invasive carcinoma arising in colorectal polyps. Gastroenterology. 1995;109:1801-7.
    • (1995) Gastroenterology , vol.109 , pp. 1801-1807
    • Volk, E.E.1    Goldblum, J.R.2    Petras, R.E.3    Carey, W.D.4    Fazio, V.W.5
  • 16
    • 0024536711 scopus 로고
    • Factors influencing mortality after curative resection for large bowel cancer in elderly patients
    • Fielding LP, Phillips RKS, Hittinger R. Factors influencing mortality after curative resection for large bowel cancer in elderly patients. Lancet. 1989;18:595-7.
    • (1989) Lancet , vol.18 , pp. 595-597
    • Fielding, L.P.1    Phillips, R.K.S.2    Hittinger, R.3
  • 17
    • 77953289296 scopus 로고    scopus 로고
    • The concurrence of histologically positive resection margins and sessile morphology is an important risk factor for lymph node metastasis after complete endoscopic removal of malignant colorectal polyps
    • Boenicke L, Fein M, Sailer M, Isbert C, Germer C-T, Thalheimer A. The concurrence of histologically positive resection margins and sessile morphology is an important risk factor for lymph node metastasis after complete endoscopic removal of malignant colorectal polyps. Int J Colorectal Dis. 2010;25:433-8.
    • (2010) Int J Colorectal Dis , vol.25 , pp. 433-438
    • Boenicke, L.1    Fein, M.2    Sailer, M.3    Isbert, C.4    Germer, C.-T.5    Thalheimer, A.6
  • 18
    • 84867988580 scopus 로고    scopus 로고
    • Additional colectomy after colonoscopic polypectomy for T1 colon cancer: A fine balance between oncologic benefit and operative risk
    • Benizri EI, Bereder J-M, Rahili A, Bernard J-L, Vanbiervliet G, Filippi J, et al. Additional colectomy after colonoscopic polypectomy for T1 colon cancer: a fine balance between oncologic benefit and operative risk. Int J Colorectal Dis. 2012;27:1473-8.
    • (2012) Int J Colorectal Dis , vol.27 , pp. 1473-1478
    • Benizri, E.I.1    Bereder, J.-M.2    Rahili, A.3    Bernard, J.-L.4    Vanbiervliet, G.5    Filippi, J.6
  • 19
    • 84867122727 scopus 로고    scopus 로고
    • ESMOconsensus guidelines for management of patients with colon and rectal cancer.Apersonalized approach to clinical decision making
    • Schmoll HJ, Van Cutsem V, Stein A, Valentini V, Glimelius B, Haustermans K, et al.ESMOconsensus guidelines for management of patients with colon and rectal cancer.Apersonalized approach to clinical decision making. Ann Oncol. 2012;23:2479-516.
    • (2012) Ann Oncol , vol.23 , pp. 2479-2516
    • Schmoll, H.J.1    Van Cutsem, V.2    Stein, A.3    Valentini, V.4    Glimelius, B.5    Haustermans, K.6
  • 20
    • 84862296538 scopus 로고    scopus 로고
    • Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer
    • Watanabe T, Itabashi M, Shimada Y, Tanaka S, Ito Y, Ajioka Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer. Int J Clin Oncol. 2009;17:1-29.
    • (2009) Int J Clin Oncol , vol.17 , pp. 1-29
    • Watanabe, T.1    Itabashi, M.2    Shimada, Y.3    Tanaka, S.4    Ito, Y.5    Ajioka, Y.6
  • 22
    • 84871501676 scopus 로고    scopus 로고
    • Colorectal carcinoma grading by quantifying poorly differentiated cell clusters is more reproducible and provides more robust prognostic information than conventional grading
    • Barresi V, Bonetti LR, Branca G, Gregorio CD, de Leon MP, Tuccari G. Colorectal carcinoma grading by quantifying poorly differentiated cell clusters is more reproducible and provides more robust prognostic information than conventional grading. Virchows Arch. 2012;461:621-8.
    • (2012) Virchows Arch , vol.461 , pp. 621-628
    • Barresi, V.1    Bonetti, L.R.2    Branca, G.3    Gregorio, C.D.4    de Leon, M.P.5    Tuccari, G.6
  • 24
    • 0021810993 scopus 로고
    • Prognostic factors in colorectal carcinomas arising in adenomas: Implications for lesions removed by endoscopic polypectomy
    • Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology. 1985;89:328-36.
    • (1985) Gastroenterology , vol.89 , pp. 328-336
    • Haggitt, R.C.1    Glotzbach, R.E.2    Soffer, E.E.3    Wruble, L.D.4
  • 28
    • 0027500802 scopus 로고
    • Endoscopic mucosal resection of flat and depressed types of early colorectal cancer
    • Kudo S. Endoscopic mucosal resection of flat and depressed types of early colorectal cancer. Endoscopy. 1993;25:455-61.
    • (1993) Endoscopy , vol.25 , pp. 455-461
    • Kudo, S.1
  • 29
    • 0028785465 scopus 로고
    • Management of early invasive colorectal cancerrisk of recurrence and clinical guidelines
    • Kikuchi R, Takano M, Takagi K, Fujimoto N, Nozaki R, Fujiyoshi T, et al. Management of early invasive colorectal cancerrisk of recurrence and clinical guidelines. Dis Colon Rectum. 1995;38:1286-95.
    • (1995) Dis Colon Rectum , vol.38 , pp. 1286-1295
    • Kikuchi, R.1    Takano, M.2    Takagi, K.3    Fujimoto, N.4    Nozaki, R.5    Fujiyoshi, T.6
  • 30
    • 0037322977 scopus 로고    scopus 로고
    • Risk of lymph node and distant metastases in patients with early invasive colorectal cancer classified as Haggitt's level 4 invasion
    • Suzuki T, Sadahiro S, Mukoyama S, Ishikawa K, Yasuda S, Tajima T, et al. Risk of lymph node and distant metastases in patients with early invasive colorectal cancer classified as Haggitt's level 4 invasion. Dis Colon Rectum. 2003;46:203-8.
    • (2003) Dis Colon Rectum , vol.46 , pp. 203-208
    • Suzuki, T.1    Sadahiro, S.2    Mukoyama, S.3    Ishikawa, K.4    Yasuda, S.5    Tajima, T.6
  • 31
    • 77955172282 scopus 로고    scopus 로고
    • Pathological prognostic factors predicting lymph node metastasis in submucosal invasive (T1) colorectal carcinoma
    • Tateishi Y, Nakanishi Y, Taniguchi H, Shimoda T, Uemura S. Pathological prognostic factors predicting lymph node metastasis in submucosal invasive (T1) colorectal carcinoma. Mod Pathol. 2010;23:1068-72.
    • (2010) Mod Pathol , vol.23 , pp. 1068-1072
    • Tateishi, Y.1    Nakanishi, Y.2    Taniguchi, H.3    Shimoda, T.4    Uemura, S.5
  • 32
    • 0027793178 scopus 로고
    • Clinicopathological characteristics of colorectal submucosal carcinoma with lymph node metastasis
    • Araki Y, Isomoto H, Shirouzu K, Miura K, Iwanaga H, Okita A, et al. Clinicopathological characteristics of colorectal submucosal carcinoma with lymph node metastasis. Kurume Med J. 1993;40:123-7.
    • (1993) Kurume Med J , vol.40 , pp. 123-127
    • Araki, Y.1    Isomoto, H.2    Shirouzu, K.3    Miura, K.4    Iwanaga, H.5    Okita, A.6
  • 34
    • 3042804834 scopus 로고    scopus 로고
    • Analysis of pathological risk factors for lymph node metastasis of submucosal invasive colon cancer
    • Egashira Y, Yoshida T, Hirata I, Hamamoto N, Akutagawa H, Takeshita A, et al. Analysis of pathological risk factors for lymph node metastasis of submucosal invasive colon cancer. Mod Pathol. 2004;17:503-11.
    • (2004) Mod Pathol , vol.17 , pp. 503-511
    • Egashira, Y.1    Yoshida, T.2    Hirata, I.3    Hamamoto, N.4    Akutagawa, H.5    Takeshita, A.6
  • 35
    • 22944491767 scopus 로고    scopus 로고
    • Myofibroblasts correlate with lymphatic microvessel density and lymph node metastasis in early-stage invasive colorectal carcinoma
    • Liang P, Hong J-W, Ubukata H, Liu G, Katano M, Motohashi G, et al. Myofibroblasts correlate with lymphatic microvessel density and lymph node metastasis in early-stage invasive colorectal carcinoma. Anticancer Res. 2005;25:2705-12.
    • (2005) Anticancer Res , vol.25 , pp. 2705-2712
    • Liang, P.1    Hong, J.-W.2    Ubukata, H.3    Liu, G.4    Katano, M.5    Motohashi, G.6
  • 36
    • 0034887516 scopus 로고    scopus 로고
    • Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer
    • Oh-e H, Tanaka S, Kitadai Y, Shimamoto F, Yoshihara M, Haruma K. Angiogenesis at the site of deepest penetration predicts lymph node metastasis of submucosal colorectal cancer. Dis Colon Rectum. 2001;44:1129-36.
    • (2001) Dis Colon Rectum , vol.44 , pp. 1129-1136
    • Ohe, H.1    Tanaka, S.2    Kitadai, Y.3    Shimamoto, F.4    Yoshihara, M.5    Haruma, K.6
  • 38
    • 3242878100 scopus 로고    scopus 로고
    • Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: A Japanese collaboration study
    • Kitajima K, Fujimori T, Fujii S, Takeda J, Ohkura Y, Kawamata H, et al. Correlations between lymph node metastasis and depth of submucosal invasion in submucosal invasive colorectal carcinoma: a Japanese collaboration study. J Gastroenterol. 2004;39:534-43.
    • (2004) J Gastroenterol , vol.39 , pp. 534-543
    • Kitajima, K.1    Fujimori, T.2    Fujii, S.3    Takeda, J.4    Ohkura, Y.5    Kawamata, H.6
  • 39
    • 33845599552 scopus 로고    scopus 로고
    • Tumour budding in colorectal carcinoma
    • Prall E. Tumour budding in colorectal carcinoma. Histopathology. 2007;50:151-62.
    • (2007) Histopathology , vol.50 , pp. 151-162
    • Prall, E.1
  • 40
    • 84861457224 scopus 로고    scopus 로고
    • Tumour budding: A promising parameter in colorectal cancer
    • Lugli A, Karamitopoulou E, Zlobec I. Tumour budding: a promising parameter in colorectal cancer. Br J Cancer. 2012;106: 1713-7.
    • (2012) Br J Cancer , vol.106 , pp. 1713-1717
    • Lugli, A.1    Karamitopoulou, E.2    Zlobec, I.3
  • 41
    • 33846433124 scopus 로고    scopus 로고
    • Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer
    • Kaneko I, Shinji S, Oka S, Kawamura T, Hiyama T, Ito M, et al. Lymphatic vessel density at the site of deepest penetration as a predictor of lymph node metastasis in submucosal colorectal cancer. Dis Colon Rectum. 2006;50:13-21.
    • (2006) Dis Colon Rectum , vol.50 , pp. 13-21
    • Kaneko, I.1    Shinji, S.2    Oka, S.3    Kawamura, T.4    Hiyama, T.5    Ito, M.6
  • 42
    • 34547990276 scopus 로고    scopus 로고
    • Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer
    • Kaneko I, Tanaka S, Oka S, Yoshida S, Hiyama T, Arihiro K, et al. Immunohistochemical molecular markers as predictors of curability of endoscopically resected submucosal colorectal cancer. World J Gastroenterol. 2007;28:3829-35.
    • (2007) World J Gastroenterol , vol.28 , pp. 3829-3835
    • Kaneko, I.1    Tanaka, S.2    Oka, S.3    Yoshida, S.4    Hiyama, T.5    Arihiro, K.6
  • 44
    • 70350450358 scopus 로고    scopus 로고
    • Evaluation of venous invasion by elastica van Gieson stain and tumor budding predicts local and distant metastases in patients with T1 stage colorectal cancer
    • Suzuki A, Togashi K, Nokubi M, Koinuma K, Miyakura Y, Horie H, et al. Evaluation of venous invasion by elastica van Gieson stain and tumor budding predicts local and distant metastases in patients with T1 stage colorectal cancer. Am J Surg Pathol. 2009;33:1601-7.
    • (2009) Am J Surg Pathol , vol.33 , pp. 1601-1607
    • Suzuki, A.1    Togashi, K.2    Nokubi, M.3    Koinuma, K.4    Miyakura, Y.5    Horie, H.6
  • 45
    • 79251561871 scopus 로고    scopus 로고
    • Is ''depth of submucosal invasion[=1,000 mm'' an important predictive factor for lymph node metastasis in early invasive colorectal cancer (PT1)?
    • Komori K, Hirai T, Kanemitsu Y, Shimizu Y, Sano T, Ito S, et al. Is ''depth of submucosal invasion[=1,000 mm'' an important predictive factor for lymph node metastasis in early invasive colorectal cancer (PT1)? Hepatogastroenterology. 2010;57: 1123-7.
    • (2010) Hepatogastroenterology , vol.57 , pp. 1123-1127
    • Komori, K.1    Hirai, T.2    Kanemitsu, Y.3    Shimizu, Y.4    Sano, T.5    Ito, S.6
  • 46
    • 84861466427 scopus 로고    scopus 로고
    • Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection
    • Nakadoi K, Tanaka S, Kanao H, Terasaki M, Takata S, Oka S, et al. Management of T1 colorectal carcinoma with special reference to criteria for curative endoscopic resection. J Gastroenterol Hepatol. 2012;27:1057-62.
    • (2012) J Gastroenterol Hepatol , vol.27 , pp. 1057-1062
    • Nakadoi, K.1    Tanaka, S.2    Kanao, H.3    Terasaki, M.4    Takata, S.5    Oka, S.6
  • 48
    • 33947187210 scopus 로고    scopus 로고
    • Recommendations for the reporting of surgically resected specimens of colorectal carcinoma
    • Jass JR, O'Brien MJ, Riddell RH, Snover DC. Recommendations for the reporting of surgically resected specimens of colorectal carcinoma. Hum Pathol. 2007;38:537-45.
    • (2007) Hum Pathol , vol.38 , pp. 537-545
    • Jass, J.R.1    O'Brien, M.J.2    Riddell, R.H.3    Snover, D.C.4
  • 49
    • 78650783032 scopus 로고    scopus 로고
    • 1st edn. Accessed Feb 19 2013
    • The Royal College of Pathologists of Australasia. Colorectal cancer structured reporting protocol, 1st edn. 2010. http://www. rcpa.edu.au. Accessed Feb 19 2013.
    • (2010) Colorectal cancer structured reporting protocol
  • 51
    • 31444456086 scopus 로고    scopus 로고
    • Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2
    • Kazama S, Watanabe T, Ajioka Y, Kanazawa T, Nagawa H. Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2. Br J Cancer. 2006;94: 293-8.
    • (2006) Br J Cancer , vol.94 , pp. 293-298
    • Kazama, S.1    Watanabe, T.2    Ajioka, Y.3    Kanazawa, T.4    Nagawa, H.5
  • 52
    • 39049151426 scopus 로고    scopus 로고
    • Histopathologic determinants of regional lymph node metastasis in early colorectal cancer
    • Ishikawa Y, Akishima-Fukasawa Y, Ito K, Akasaka Y, Yokoo T, Ishii T. Histopathologic determinants of regional lymph node metastasis in early colorectal cancer. Cancer. 2008;112:924-33.
    • (2008) Cancer , vol.112 , pp. 924-933
    • Ishikawa, Y.1    Akishima-Fukasawa, Y.2    Ito, K.3    Akasaka, Y.4    Yokoo, T.5    Ishii, T.6
  • 53
    • 67651120152 scopus 로고    scopus 로고
    • Tumor budding is predictive of lymphatic involvement and lymph node metastases in submucosal invasive colorectal adenocarcinomas and in non-polypoid compared with polypoid growths
    • Ogawa T, Yoshida T, Tsuruta T, Tokuyama W, Adachi S, Kikuchi M, et al. Tumor budding is predictive of lymphatic involvement and lymph node metastases in submucosal invasive colorectal adenocarcinomas and in non-polypoid compared with polypoid growths. Scand J Gastroenterol. 2009;44:605-14.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 605-614
    • Ogawa, T.1    Yoshida, T.2    Tsuruta, T.3    Tokuyama, W.4    Adachi, S.5    Kikuchi, M.6
  • 54
    • 84876466556 scopus 로고    scopus 로고
    • Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer
    • (Epub ahead of print)
    • Horcic M, Koelzer VH, Karamitopoulou E, Terracciano L, Puppa G, Zlobec I, et al. Tumor budding score based on 10 high-power fields is a promising basis for a standardized prognostic scoring system in stage II colorectal cancer. Hum Pathol. 2012 (Epub ahead of print).
    • (2012) Hum Pathol
    • Horcic, M.1    Koelzer, V.H.2    Karamitopoulou, E.3    Terracciano, L.4    Puppa, G.5    Zlobec, I.6
  • 55
    • 84871925029 scopus 로고    scopus 로고
    • Diagnostic reproducibility of tumour budding in colorectal cancer: A multicentre, multinational study using virtual microscopy
    • (Epub ahead print)
    • Puppa G, Senore C, Sheahan K, Vieth M, Lugli A, Zlobec I, et al. Diagnostic reproducibility of tumour budding in colorectal cancer: a multicentre, multinational study using virtual microscopy. Histopathology. 2012 (Epub ahead print).
    • (2012) Histopathology
    • Puppa, G.1    Senore, C.2    Sheahan, K.3    Vieth, M.4    Lugli, A.5    Zlobec, I.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.