메뉴 건너뛰기




Volumn 94, Issue 2, 2006, Pages 293-298

Tumour budding at the deepest invasive margin correlates with lymph node metastasis in submucosal colorectal cancer detected by anticytokeratin antibody CAM5.2

Author keywords

CAM5.2; D2 40; Isolated tumour cells; Micrometastasis; Tumour budding

Indexed keywords

CYTOKERATIN ANTIBODY; CYTOKERATIN ANTIBODY CAM5.2; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 31444456086     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6602927     Document Type: Article
Times cited : (99)

References (38)
  • 1
    • 0033978219 scopus 로고    scopus 로고
    • Micrometastasis in lymph nodes and microinvasion of the muscularis propria in primary lesions of submucosal gastric cancer
    • Cai J, Ikeguchi M, Maeta M, Kaibara N (1999) Micrometastasis in lymph nodes and microinvasion of the muscularis propria in primary lesions of submucosal gastric cancer. Surgery 127: 32-39
    • (1999) Surgery , vol.127 , pp. 32-39
    • Cai, J.1    Ikeguchi, M.2    Maeta, M.3    Kaibara, N.4
  • 2
    • 3042757006 scopus 로고    scopus 로고
    • Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40
    • Fogt F, Zimmerman RL, Ross HM, Daly T, Gausas RE (2004) Identification of lymphatic vessels in malignant, adenomatous and normal colonic mucosa using the novel immunostain D2-40. Oncol Rep 11: 47-50
    • (2004) Oncol Rep , vol.11 , pp. 47-50
    • Fogt, F.1    Zimmerman, R.L.2    Ross, H.M.3    Daly, T.4    Gausas, R.E.5
  • 3
    • 4143121238 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis in head and neck squamous cell carcinoma: A morphometric study with clinical correlations
    • Franchi A, Gallo O, Massi D, Baroni G, Santucci M (2004) Tumor lymphangiogenesis in head and neck squamous cell carcinoma: a morphometric study with clinical correlations. Cancer 101: 973-978
    • (2004) Cancer , vol.101 , pp. 973-978
    • Franchi, A.1    Gallo, O.2    Massi, D.3    Baroni, G.4    Santucci, M.5
  • 4
    • 0032925597 scopus 로고    scopus 로고
    • Histologic features associated with lymph node metastasis in stage T1 and superficial T2 rectal adenocarcinomas in abdominoperineal resection specimens. Identifying a subset of patients for whom treatment with adjuvant therapy or completion abdominoperineal resection should be considered after local excision
    • Goldstein NS, Hart J (1999) Histologic features associated with lymph node metastasis in stage T1 and superficial T2 rectal adenocarcinomas in abdominoperineal resection specimens. Identifying a subset of patients for whom treatment with adjuvant therapy or completion abdominoperineal resection should be considered after local excision. Am J Clin Pathol 111: 51-58
    • (1999) Am J Clin Pathol , vol.111 , pp. 51-58
    • Goldstein, N.S.1    Hart, J.2
  • 6
    • 0026763520 scopus 로고
    • The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma
    • Haboubi NY, Clark P, Kaftan SM, Schofield PF (1992) The importance of combining xylene clearance and immunohistochemistry in the accurate staging of colorectal carcinoma. J R Soc Med 85: 386-388
    • (1992) J R Soc Med , vol.85 , pp. 386-388
    • Haboubi, N.Y.1    Clark, P.2    Kaftan, S.M.3    Schofield, P.F.4
  • 7
    • 0021810993 scopus 로고
    • Prognostic factors in colorectal carcinomas arising in adenomas: Implications for lesions removed by endoscopic polypectomy
    • Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD (1985) Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology 89: 328-336
    • (1985) Gastroenterology , vol.89 , pp. 328-336
    • Haggitt, R.C.1    Glotzbach, R.E.2    Soffer, E.E.3    Wruble, L.D.4
  • 8
    • 0027272850 scopus 로고
    • Prognostic value of tumor 'budding' in patients with colorectal cancer
    • Hase K, Shatney C, Johnson D, Trollope M, Vierra M (1993) Prognostic value of tumor 'budding' in patients with colorectal cancer. Dis Colon Rectum 36: 627-635
    • (1993) Dis Colon Rectum , vol.36 , pp. 627-635
    • Hase, K.1    Shatney, C.2    Johnson, D.3    Trollope, M.4    Vierra, M.5
  • 9
    • 0033573070 scopus 로고    scopus 로고
    • Classification of isolated tumor cells and micrometastasis
    • International Union Against Cancer
    • Hermanek P, Hutter RV, Sobin LH, Wittekind C (1999) International Union Against Cancer. classification of isolated tumor cells and micrometastasis. Cancer 86: 2668-2673
    • (1999) Cancer , vol.86 , pp. 2668-2673
    • Hermanek, P.1    Hutter, R.V.2    Sobin, L.H.3    Wittekind, C.4
  • 10
    • 0032766836 scopus 로고    scopus 로고
    • Prognostic significance of perirectal lymph node micrometastases in Dukes' B rectal carcinoma: An immunohistochemical study by CAM5.2
    • Isaka N, Nozue M, Doy M, Fukao K (1999) Prognostic significance of perirectal lymph node micrometastases in Dukes' B rectal carcinoma: an immunohistochemical study by CAM5.2. Clin Cancer Res 5: 2065-2068
    • (1999) Clin Cancer Res , vol.5 , pp. 2065-2068
    • Isaka, N.1    Nozue, M.2    Doy, M.3    Fukao, K.4
  • 12
    • 0035149139 scopus 로고    scopus 로고
    • The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation
    • Jung A, Schrauder M, Oswald U, Knoll C, Sellberg P, Palmqvist R, Niedobitek G, Brabletz T, Kirchner T (2001) The invasion front of human colorectal adenocarcinomas shows co-localization of nuclear beta-catenin, cyclin D1, and p16INK4A and is a region of low proliferation. Am J Pathol 159: 1613-1617
    • (2001) Am J Pathol , vol.159 , pp. 1613-1617
    • Jung, A.1    Schrauder, M.2    Oswald, U.3    Knoll, C.4    Sellberg, P.5    Palmqvist, R.6    Niedobitek, G.7    Brabletz, T.8    Kirchner, T.9
  • 13
    • 0036715251 scopus 로고    scopus 로고
    • A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors
    • Kahn HJ, Marks A (2002) A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest 82: 1255-1257
    • (2002) Lab Invest , vol.82 , pp. 1255-1257
    • Kahn, H.J.1    Marks, A.2
  • 17
    • 0035889961 scopus 로고    scopus 로고
    • Possible contribution of CD44 variant 6 and nuclear beta-catenin expression to the formation of budding tumor cells in patients with T1 colorectal carcinoma
    • Masaki T, Goto A, Sugiyama M, Matsuoka H, Abe N, Sakamoto A, Atomi Y (2001a) Possible contribution of CD44 variant 6 and nuclear beta-catenin expression to the formation of budding tumor cells in patients with T1 colorectal carcinoma. Cancer 92: 2539-2546
    • (2001) Cancer , vol.92 , pp. 2539-2546
    • Masaki, T.1    Goto, A.2    Sugiyama, M.3    Matsuoka, H.4    Abe, N.5    Sakamoto, A.6    Atomi, Y.7
  • 18
    • 0035906826 scopus 로고    scopus 로고
    • Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas
    • Masaki T, Matsuoka H, Sugiyama M, Abe N, Goto A, Sakamoto A, Atomi Y (2001b) Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas. Br J Cancer 84: 1317-1321
    • (2001) Br J Cancer , vol.84 , pp. 1317-1321
    • Masaki, T.1    Matsuoka, H.2    Sugiyama, M.3    Abe, N.4    Goto, A.5    Sakamoto, A.6    Atomi, Y.7
  • 19
    • 0038726469 scopus 로고    scopus 로고
    • Coexpression of matrilysin and laminin-5 gamma2 chain may contribute to tumor cell migration in colorectal carcinomas
    • Masaki T, Sugiyama M, Matsuoka H, Abe N, Izumisato Y, Sakamoto A, Atomi Y (2003) Coexpression of matrilysin and laminin-5 gamma2 chain may contribute to tumor cell migration in colorectal carcinomas. Dig Dis Sci 48: 1262-1267
    • (2003) Dig Dis Sci , vol.48 , pp. 1262-1267
    • Masaki, T.1    Sugiyama, M.2    Matsuoka, H.3    Abe, N.4    Izumisato, Y.5    Sakamoto, A.6    Atomi, Y.7
  • 20
    • 0020467073 scopus 로고
    • The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
    • Moll R, Franke WW, Schiller DL, Geiger B, Krepler R (1982) The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell 31: 11-24
    • (1982) Cell , vol.31 , pp. 11-24
    • Moll, R.1    Franke, W.W.2    Schiller, D.L.3    Geiger, B.4    Krepler, R.5
  • 21
    • 0024599662 scopus 로고
    • An index for estimating the probability of lymph node metastasis in rectal cancers. Lymph node metastasis and the histopathology of actively invasive regions of cancer
    • Morodomi T, Isomoto H, Shirouzu K, Kakegawa K, Irie K, Morimatsu M (1989) An index for estimating the probability of lymph node metastasis in rectal cancers. Lymph node metastasis and the histopathology of actively invasive regions of cancer. Cancer 63: 539-543
    • (1989) Cancer , vol.63 , pp. 539-543
    • Morodomi, T.1    Isomoto, H.2    Shirouzu, K.3    Kakegawa, K.4    Irie, K.5    Morimatsu, M.6
  • 22
    • 0017606229 scopus 로고
    • Policy of local excision for early cancer of the colorectum
    • Morson BC, Bussey HJ, Samoorian S (1977) Policy of local excision for early cancer of the colorectum. Gut 18: 1045-1050
    • (1977) Gut , vol.18 , pp. 1045-1050
    • Morson, B.C.1    Bussey, H.J.2    Samoorian, S.3
  • 23
  • 24
    • 0031751217 scopus 로고    scopus 로고
    • Are lymph node micrometastases of any clinical significance in Dukes Stages A and B colorectal cancer?
    • Oberg A, Stenling R, Tavelin B, Lindmark G (1998) Are lymph node micrometastases of any clinical significance in Dukes Stages A and B colorectal cancer? Dis Colon Rectum 41: 1244-1249
    • (1998) Dis Colon Rectum , vol.41 , pp. 1244-1249
    • Oberg, A.1    Stenling, R.2    Tavelin, B.3    Lindmark, G.4
  • 25
    • 0036251472 scopus 로고    scopus 로고
    • Budding as a risk factor for lymph node metastasis in pT1 or pT2 well-differentiated colorectal adenocarcinoma
    • Okuyama T, Oya M, Ishikawa H (2002) Budding as a risk factor for lymph node metastasis in pT1 or pT2 well-differentiated colorectal adenocarcinoma. Dis Colon Rectum 45: 628-634
    • (2002) Dis Colon Rectum , vol.45 , pp. 628-634
    • Okuyama, T.1    Oya, M.2    Ishikawa, H.3
  • 26
    • 0029810605 scopus 로고    scopus 로고
    • Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in the primary lesion of patients with colorectal carcinoma with liver metastasis
    • Ono M, Sakamoto M, Ino Y, Moriya Y, Sugihara K, Muto T, Hirohashi S (1996) Cancer cell morphology at the invasive front and expression of cell adhesion-related carbohydrate in the primary lesion of patients with colorectal carcinoma with liver metastasis. Cancer 78: 1179-1186
    • (1996) Cancer , vol.78 , pp. 1179-1186
    • Ono, M.1    Sakamoto, M.2    Ino, Y.3    Moriya, Y.4    Sugihara, K.5    Muto, T.6    Hirohashi, S.7
  • 27
    • 22744438539 scopus 로고    scopus 로고
    • Intensity of tumor budding and its prognostic implications in invasive colon carcinoma
    • Park KJ, Choi HJ, Roh MS, Kwon HC, Kim C (2005) Intensity of tumor budding and its prognostic implications in invasive colon carcinoma. Dis Colon Rectum 48: 1597-1602
    • (2005) Dis Colon Rectum , vol.48 , pp. 1597-1602
    • Park, K.J.1    Choi, H.J.2    Roh, M.S.3    Kwon, H.C.4    Kim, C.5
  • 28
    • 0031910672 scopus 로고    scopus 로고
    • Immunoperoxidase staining for cytokeratins 8 and 18 is very sensitive for detection of occult node metastasis of colorectal cancer: A comparison with genetic analysis of K-ras
    • Sasaki M, Watanabe H, Jass JR, Ajioka Y, Kobayashi M, Hatakeyama K (1998) Immunoperoxidase staining for cytokeratins 8 and 18 is very sensitive for detection of occult node metastasis of colorectal cancer: a comparison with genetic analysis of K-ras. Histopathology 32: 199-208
    • (1998) Histopathology , vol.32 , pp. 199-208
    • Sasaki, M.1    Watanabe, H.2    Jass, J.R.3    Ajioka, Y.4    Kobayashi, M.5    Hatakeyama, K.6
  • 29
    • 0034568845 scopus 로고    scopus 로고
    • Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment
    • Sordat I, Rousselle P, Chaubert P, Petermann O, Aberdam D, Bosman FT, Sordat B (2000) Tumor cell budding and laminin-5 expression in colorectal carcinoma can be modulated by the tissue micro-environment. Int J Cancer 88: 708-717
    • (2000) Int J Cancer , vol.88 , pp. 708-717
    • Sordat, I.1    Rousselle, P.2    Chaubert, P.3    Petermann, O.4    Aberdam, D.5    Bosman, F.T.6    Sordat, B.7
  • 30
    • 0042529110 scopus 로고    scopus 로고
    • Tumor budding at the invasive margin can predict patients at high risk of recurrence after curative surgery for stage II, T3 colon cancer
    • Tanaka M, Hashiguchi Y, Ueno H, Hase K, Mochizuki H (2003) Tumor budding at the invasive margin can predict patients at high risk of recurrence after curative surgery for stage II, T3 colon cancer. Dis Colon Rectum 46: 1054-1059
    • (2003) Dis Colon Rectum , vol.46 , pp. 1054-1059
    • Tanaka, M.1    Hashiguchi, Y.2    Ueno, H.3    Hase, K.4    Mochizuki, H.5
  • 31
    • 85047694512 scopus 로고    scopus 로고
    • Immunohistochemically demonstrated lymph node micrometastasis and prognosis in patients with otherwise node-negative hilar cholangiocarcinoma
    • Tojima Y, Nagino M, Ebata T, Uesaka K, Kamiya J, Nimura Y (2003) Immunohistochemically demonstrated lymph node micrometastasis and prognosis in patients with otherwise node-negative hilar cholangiocarcinoma. Ann Surg 237: 201-207
    • (2003) Ann Surg , vol.237 , pp. 201-207
    • Tojima, Y.1    Nagino, M.2    Ebata, T.3    Uesaka, K.4    Kamiya, J.5    Nimura, Y.6
  • 32
    • 0035014806 scopus 로고    scopus 로고
    • Endoscopic treatment of colorectal polyps and early cancer
    • Tung SY, Wu CS, Wu MC, Su MY (2001) Endoscopic treatment of colorectal polyps and early cancer. Dig Dis Sci 46: 1152-1156
    • (2001) Dig Dis Sci , vol.46 , pp. 1152-1156
    • Tung, S.Y.1    Wu, C.S.2    Wu, M.C.3    Su, M.Y.4
  • 34
    • 0036164967 scopus 로고    scopus 로고
    • Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer
    • Ueno H, Murphy J, Jass JR, Mochizuki H, Talbot IC (2002) Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer. Histopathology 40: 127-132
    • (2002) Histopathology , vol.40 , pp. 127-132
    • Ueno, H.1    Murphy, J.2    Jass, J.R.3    Mochizuki, H.4    Talbot, I.C.5
  • 35
    • 0022657987 scopus 로고
    • Early invasive carcinoma in colonic polyps. A review of the literature with emphasis on the assessment of the risk of metastasis
    • Wilcox GM, Anderson PB, Colacchio TA (1986) Early invasive carcinoma in colonic polyps. A review of the literature with emphasis on the assessment of the risk of metastasis. Cancer 57: 160-171
    • (1986) Cancer , vol.57 , pp. 160-171
    • Wilcox, G.M.1    Anderson, P.B.2    Colacchio, T.A.3
  • 36
    • 0033810104 scopus 로고    scopus 로고
    • Endoscopic management of polypoid early colon cancer
    • Williams CB, Saunders BP, Talbot IC (2000) Endoscopic management of polypoid early colon cancer. World J Surg 24: 1047-1051
    • (2000) World J Surg , vol.24 , pp. 1047-1051
    • Williams, C.B.1    Saunders, B.P.2    Talbot, I.C.3
  • 38
    • 0033121110 scopus 로고    scopus 로고
    • Immunohistochemical detection of lymph node micrometastases from gallbladder carcinoma using monoclonal anticytokeratin antibody
    • Yokoyama N, Shirai Y, Hatakeyama K (1999) Immunohistochemical detection of lymph node micrometastases from gallbladder carcinoma using monoclonal anticytokeratin antibody. Cancer 85: 1465-1469
    • (1999) Cancer , vol.85 , pp. 1465-1469
    • Yokoyama, N.1    Shirai, Y.2    Hatakeyama, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.