메뉴 건너뛰기




Volumn 15, Issue 11, 2014, Pages 825-829

Anticholinergic Drug Use and Negative Outcomes Among the Frail Elderly Population Living in a Nursing Home

Author keywords

Anticholinergic medications; Delirium; Falls; Functional decline

Indexed keywords

AMANTADINE; AMITRIPTYLINE; ATROPINE; BENZATROPINE MESILATE; CARISOPRODOL; CHLORPHENIRAMINE MALEATE; CHLORPROMAZINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CYPROHEPTADINE; DICYCLOVERINE; DIPHENHYDRAMINE; FLUPHENAZINE; HALOPERIDOL; HYDROXYZINE; HYDROXYZINE EMBONATE; HYOSCYAMINE; IMIPRAMINE; LEVODOPA; MECLOZINE; OXYBUTYNIN; PAROXETINE; PERPHENAZINE; PROMETHAZINE; QUETIAPINE; RISPERIDONE; THIORIDAZINE; TIOTIXENE; TIZANIDINE; TRIFLUOPERAZINE; UNINDEXED DRUG;

EID: 84908223855     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2014.08.002     Document Type: Article
Times cited : (102)

References (42)
  • 1
    • 84884151512 scopus 로고    scopus 로고
    • Medication reconciliation in continuum of care transitions: A moving target
    • Sinvani L.D., Beizer J., Akerman M., et al. Medication reconciliation in continuum of care transitions: A moving target. JAm Med Dir Assoc 2013, 14:668-672.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 668-672
    • Sinvani, L.D.1    Beizer, J.2    Akerman, M.3
  • 2
    • 84878836322 scopus 로고    scopus 로고
    • Exploratory evaluation of medication classes most commonly involved in nursing home errors
    • Desai R.J., Williams C.E., Greene S.B., et al. Exploratory evaluation of medication classes most commonly involved in nursing home errors. JAm Med Dir Assoc 2013, 14:403-408.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 403-408
    • Desai, R.J.1    Williams, C.E.2    Greene, S.B.3
  • 3
    • 27644480374 scopus 로고    scopus 로고
    • Impact of inappropriate drug use among hospitalized older adults
    • Onder G., Landi F., Liperoti R., et al. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol 2005, 61:453-459.
    • (2005) Eur J Clin Pharmacol , vol.61 , pp. 453-459
    • Onder, G.1    Landi, F.2    Liperoti, R.3
  • 4
    • 84876799013 scopus 로고    scopus 로고
    • The development and test of an intervention to improve ADR screening in nursing homes
    • Dilles T., Vander Stichele R.H., Van Bortel L.M., Elseviers M.M. The development and test of an intervention to improve ADR screening in nursing homes. JAm Med Dir Assoc 2013, 14:379.e1-379.e6.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 379.e1-379.e6
    • Dilles, T.1    Vander Stichele, R.H.2    Van Bortel, L.M.3    Elseviers, M.M.4
  • 5
    • 0030802061 scopus 로고    scopus 로고
    • Explicit criteria for determining potentially inappropriate medication use by the elderly. An update
    • Beers M.H. Explicit criteria for determining potentially inappropriate medication use by the elderly. An update. Arch Intern Med 1997, 157:1531-1536.
    • (1997) Arch Intern Med , vol.157 , pp. 1531-1536
    • Beers, M.H.1
  • 7
    • 80052773815 scopus 로고    scopus 로고
    • Associations between the anticholinergic risk scale score and physical function: Potential implications for adverse outcomes in older hospitalized patients
    • Lowry E., Woodman R.J., Soiza R.L., Mangoni A.A. Associations between the anticholinergic risk scale score and physical function: Potential implications for adverse outcomes in older hospitalized patients. JAm Med Dir Assoc 2011, 12:565-572.
    • (2011) JAm Med Dir Assoc , vol.12 , pp. 565-572
    • Lowry, E.1    Woodman, R.J.2    Soiza, R.L.3    Mangoni, A.A.4
  • 8
    • 33644776510 scopus 로고    scopus 로고
    • Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: Longitudinal cohort study
    • Ancelin M.L., Artero S., Portet F., et al. Non-degenerative mild cognitive impairment in elderly people and use of anticholinergic drugs: Longitudinal cohort study. BMJ 2006, 332:455-459.
    • (2006) BMJ , vol.332 , pp. 455-459
    • Ancelin, M.L.1    Artero, S.2    Portet, F.3
  • 9
    • 0036759078 scopus 로고    scopus 로고
    • Anticholinergic burden and the risk of falls among elderly psychiatric inpatients: A 4-year case-control study
    • Aizenberg D., Sigler M., Weizman A., Barak Y. Anticholinergic burden and the risk of falls among elderly psychiatric inpatients: A 4-year case-control study. Int Psychogeriatr 2002, 14:307-310.
    • (2002) Int Psychogeriatr , vol.14 , pp. 307-310
    • Aizenberg, D.1    Sigler, M.2    Weizman, A.3    Barak, Y.4
  • 10
    • 80053199964 scopus 로고    scopus 로고
    • Anticholinergic medications and cognition
    • Morley J.E. Anticholinergic medications and cognition. JAm Med Dir Assoc 2011, 12:543-543.e1.
    • (2011) JAm Med Dir Assoc , vol.12 , pp. 543-543.e1
    • Morley, J.E.1
  • 11
    • 41949083073 scopus 로고    scopus 로고
    • The anticholinergic risk scale and anticholinergic adverse effects in older persons
    • Rudolph J.L., Salow M.J., Angelini M.C., McGlinchey R.E. The anticholinergic risk scale and anticholinergic adverse effects in older persons. Arch Intern Med 2008, 168:508-513.
    • (2008) Arch Intern Med , vol.168 , pp. 508-513
    • Rudolph, J.L.1    Salow, M.J.2    Angelini, M.C.3    McGlinchey, R.E.4
  • 12
    • 84859708880 scopus 로고    scopus 로고
    • Anticholinergic drugs and their effects on delirium and mortality in the elderly
    • Luukkanen M.J., Uusvaara J., Laurila J.V., et al. Anticholinergic drugs and their effects on delirium and mortality in the elderly. Dement Geriatr Cogn Dis Extra 2011, 1:43-50.
    • (2011) Dement Geriatr Cogn Dis Extra , vol.1 , pp. 43-50
    • Luukkanen, M.J.1    Uusvaara, J.2    Laurila, J.V.3
  • 13
    • 84873129459 scopus 로고    scopus 로고
    • Prevalence and potentially reversible factors associated with anorexia among older nursing home residents: Results from the ULISSE project
    • Landi F., Lattanzio F., Dell'Aquila G., et al. Prevalence and potentially reversible factors associated with anorexia among older nursing home residents: Results from the ULISSE project. JAm Med Dir Assoc 2013, 14:119-124.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 119-124
    • Landi, F.1    Lattanzio, F.2    Dell'Aquila, G.3
  • 14
    • 84855186989 scopus 로고    scopus 로고
    • Predictors of hospitalization in Italian nursing home residents: The U.L.I.S.S.E. project
    • Cherubini A., Eusebi P., Dell'Aquila G., et al. Predictors of hospitalization in Italian nursing home residents: The U.L.I.S.S.E. project. JAm Med Dir Assoc 2012, 13:84.e5-84.e10.
    • (2012) JAm Med Dir Assoc , vol.13 , pp. 84.e5-84.e10
    • Cherubini, A.1    Eusebi, P.2    Dell'Aquila, G.3
  • 16
    • 0034573999 scopus 로고    scopus 로고
    • Minimum data set for home care: A valid instrument to assess frail older people living in the community
    • Landi F., Tua E., Onder G., et al. Minimum data set for home care: A valid instrument to assess frail older people living in the community. Med Care 2000, 38:1184-1190.
    • (2000) Med Care , vol.38 , pp. 1184-1190
    • Landi, F.1    Tua, E.2    Onder, G.3
  • 17
    • 34249931170 scopus 로고    scopus 로고
    • Anemia status, hemoglobin concentration, and mortality in nursing home older residents
    • Landi F., Russo A., Danese P., et al. Anemia status, hemoglobin concentration, and mortality in nursing home older residents. JAm Med Dir Assoc 2007, 8:322-327.
    • (2007) JAm Med Dir Assoc , vol.8 , pp. 322-327
    • Landi, F.1    Russo, A.2    Danese, P.3
  • 18
    • 84856113252 scopus 로고    scopus 로고
    • Sarcopenia and mortality among older nursing home residents
    • Landi F., Liperoti R., Fusco D., et al. Sarcopenia and mortality among older nursing home residents. JAm Med Dir Assoc 2012, 13:121-126.
    • (2012) JAm Med Dir Assoc , vol.13 , pp. 121-126
    • Landi, F.1    Liperoti, R.2    Fusco, D.3
  • 19
    • 34347393475 scopus 로고    scopus 로고
    • Preliminary derivation of a nursing home confusion assessment method based on data from the minimum data set
    • Dosa D., Intrator O., McNicoll L., et al. Preliminary derivation of a nursing home confusion assessment method based on data from the minimum data set. JAm Geriatr Soc 2007, 55:1099-1105.
    • (2007) JAm Geriatr Soc , vol.55 , pp. 1099-1105
    • Dosa, D.1    Intrator, O.2    McNicoll, L.3
  • 23
    • 67349224750 scopus 로고    scopus 로고
    • Apreliminary study of anticholinergic burden and relationship to a quality of life indicator, engagement in activities, in nursing home residents with dementia
    • Kolanowski A., Fick D.M., Campbell J., et al. Apreliminary study of anticholinergic burden and relationship to a quality of life indicator, engagement in activities, in nursing home residents with dementia. JAm Med Dir Assoc 2009, 10:252-257.
    • (2009) JAm Med Dir Assoc , vol.10 , pp. 252-257
    • Kolanowski, A.1    Fick, D.M.2    Campbell, J.3
  • 24
    • 0037315114 scopus 로고    scopus 로고
    • Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance
    • Mulsant B.H., Pollock B.G., Kirshner M., et al. Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance. Arch Gen Psychiatry 2003, 60:198-203.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 198-203
    • Mulsant, B.H.1    Pollock, B.G.2    Kirshner, M.3
  • 25
    • 84890532577 scopus 로고    scopus 로고
    • Evaluation of anticholinergic burden of medications in older adults
    • West T., Pruchnicki M.C., Porter K., Emptage R. Evaluation of anticholinergic burden of medications in older adults. JAm Pharm Assoc 2013, 53:496-504.
    • (2013) JAm Pharm Assoc , vol.53 , pp. 496-504
    • West, T.1    Pruchnicki, M.C.2    Porter, K.3    Emptage, R.4
  • 26
    • 33846563104 scopus 로고    scopus 로고
    • Anticholinergic drugs and physical function among frail elderly population
    • Landi F., Russo A., Liperoti R., et al. Anticholinergic drugs and physical function among frail elderly population. Clin Pharmacol Ther 2007, 81:235-241.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 235-241
    • Landi, F.1    Russo, A.2    Liperoti, R.3
  • 27
    • 84876274675 scopus 로고    scopus 로고
    • Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: Comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: Results from the REPOSI study
    • Pasina L., Djade C.D., Lucca U., et al. Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: Comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: Results from the REPOSI study. Drugs Aging 2013, 30:103-112.
    • (2013) Drugs Aging , vol.30 , pp. 103-112
    • Pasina, L.1    Djade, C.D.2    Lucca, U.3
  • 28
    • 79955982494 scopus 로고    scopus 로고
    • Associations between drug burden index and falls in older people in residential aged care
    • Wilson N.M., Hilmer S.N., March L.M., et al. Associations between drug burden index and falls in older people in residential aged care. JAm Geriatr Soc 2011, 59:875-880.
    • (2011) JAm Geriatr Soc , vol.59 , pp. 875-880
    • Wilson, N.M.1    Hilmer, S.N.2    March, L.M.3
  • 29
    • 0034167388 scopus 로고    scopus 로고
    • Serum anticholinergic activity levels and delirium in the elderly
    • Tune L.E. Serum anticholinergic activity levels and delirium in the elderly. Semin Clin Neuropsychiatry 2000, 5:149-153.
    • (2000) Semin Clin Neuropsychiatry , vol.5 , pp. 149-153
    • Tune, L.E.1
  • 30
    • 84878015693 scopus 로고    scopus 로고
    • The management of behavioral and psychological symptoms of dementia: The need for tailored interventions
    • Liperoti R., Landi F. The management of behavioral and psychological symptoms of dementia: The need for tailored interventions. JAm Med Dir Assoc 2013, 14:306-307.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 306-307
    • Liperoti, R.1    Landi, F.2
  • 31
    • 84884658777 scopus 로고    scopus 로고
    • Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures
    • Mangoni A.A., van Munster B.C., Woodman R.J., de Rooij S.E. Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures. Am J Geriatr Psychiatry 2013, 21:785-793.
    • (2013) Am J Geriatr Psychiatry , vol.21 , pp. 785-793
    • Mangoni, A.A.1    van Munster, B.C.2    Woodman, R.J.3    de Rooij, S.E.4
  • 32
    • 84898473029 scopus 로고    scopus 로고
    • Impact of high risk drug use on hospitalization and mortality in older people with and without Alzheimer's disease: A national population cohort study
    • Gnjidic D., Hilmer S.N., Hartikainen S., et al. Impact of high risk drug use on hospitalization and mortality in older people with and without Alzheimer's disease: A national population cohort study. PLoS One 2014, 9:e83224.
    • (2014) PLoS One , vol.9 , pp. e83224
    • Gnjidic, D.1    Hilmer, S.N.2    Hartikainen, S.3
  • 33
    • 28744450289 scopus 로고    scopus 로고
    • Cholinesterase inhibitors and anticholinergic drugs: Is the pharmacologic antagonism myth or reality?
    • Beier M.T. Cholinesterase inhibitors and anticholinergic drugs: Is the pharmacologic antagonism myth or reality?. JAm Med Dir Assoc 2005, 6:413-414.
    • (2005) JAm Med Dir Assoc , vol.6 , pp. 413-414
    • Beier, M.T.1
  • 34
    • 84897078369 scopus 로고    scopus 로고
    • Knowledge of and perceived need for evidence-based education about antipsychotic medications among nursing home leadership and staff
    • Lemay C.A., Mazor K.M., Field T.S., et al. Knowledge of and perceived need for evidence-based education about antipsychotic medications among nursing home leadership and staff. JAm Med Dir Assoc 2013, 14:895-900.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 895-900
    • Lemay, C.A.1    Mazor, K.M.2    Field, T.S.3
  • 35
    • 84908240939 scopus 로고    scopus 로고
    • Anticholinergic drugs and their effects on delirium and mortality in the elderly
    • Luukkanen M.J., Uusvaara J., Laurila J.V., et al. Anticholinergic drugs and their effects on delirium and mortality in the elderly. JAm Geriatr Soc 2011, 59:S277-S281.
    • (2011) JAm Geriatr Soc , vol.59 , pp. S277-S281
    • Luukkanen, M.J.1    Uusvaara, J.2    Laurila, J.V.3
  • 36
    • 0038053038 scopus 로고    scopus 로고
    • Inappropriate medication use among hospitalized older adults in Italy: Results from the Italian Group of Pharmacoepidemiology in the Elderly
    • Onder G., Landi F., Cesari M., Investigators of the GIFA Study, et al. Inappropriate medication use among hospitalized older adults in Italy: Results from the Italian Group of Pharmacoepidemiology in the Elderly. Eur J Clin Pharmacol 2003, 59:157-162.
    • (2003) Eur J Clin Pharmacol , vol.59 , pp. 157-162
    • Onder, G.1    Landi, F.2    Cesari, M.3
  • 37
    • 77954632583 scopus 로고    scopus 로고
    • Inappropriate drug prescriptions among older nursing-home residents: The Italian perspective
    • Ruggiero C., Lattanzio F., Dell'Aquila G., et al. Inappropriate drug prescriptions among older nursing-home residents: The Italian perspective. Drugs Aging 2009, 26:15-30.
    • (2009) Drugs Aging , vol.26 , pp. 15-30
    • Ruggiero, C.1    Lattanzio, F.2    Dell'Aquila, G.3
  • 38
    • 77956304894 scopus 로고    scopus 로고
    • Potentially inappropriate drug prescriptions and risk of hospitalization among Italian older nursing home residents: The U.L.I.S.S.E. project on behalf of the ULISSE study group
    • Ruggiero C., Dell'Aquila G., Gasperini B., for the U.L.I.S.S.E.study group, et al. Potentially inappropriate drug prescriptions and risk of hospitalization among Italian older nursing home residents: The U.L.I.S.S.E. project on behalf of the ULISSE study group. Drug Aging 2010, 27:747-758.
    • (2010) Drug Aging , vol.27 , pp. 747-758
    • Ruggiero, C.1    Dell'Aquila, G.2    Gasperini, B.3
  • 39
    • 84871687512 scopus 로고    scopus 로고
    • Improving medication use in the nursing homes: A European perspective
    • Cestac P., Tavassoli N., Vellas B., Rolland Y. Improving medication use in the nursing homes: A European perspective. JAm Med Dir Assoc 2013, 14:6-9.
    • (2013) JAm Med Dir Assoc , vol.14 , pp. 6-9
    • Cestac, P.1    Tavassoli, N.2    Vellas, B.3    Rolland, Y.4
  • 40
    • 79956288670 scopus 로고    scopus 로고
    • Physician intervention for medication reduction in a nursing home: The polypharmacy outcomes project
    • Tamura B.K., Bell C.L., Lubimir K., et al. Physician intervention for medication reduction in a nursing home: The polypharmacy outcomes project. JAm Med Dir Assoc 2011, 12:326-330.
    • (2011) JAm Med Dir Assoc , vol.12 , pp. 326-330
    • Tamura, B.K.1    Bell, C.L.2    Lubimir, K.3
  • 41
    • 79956275120 scopus 로고    scopus 로고
    • Evaluation of the fleetwood model of long-term care pharmacy
    • Lapane K.L., Hughes C.M., Christian J.B., et al. Evaluation of the fleetwood model of long-term care pharmacy. JAm Med Dir Assoc 2011, 12:355-363.
    • (2011) JAm Med Dir Assoc , vol.12 , pp. 355-363
    • Lapane, K.L.1    Hughes, C.M.2    Christian, J.B.3
  • 42
    • 84873628373 scopus 로고    scopus 로고
    • Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: A randomized controlled trial
    • Kersten H., Molden E., Tolo I.K., et al. Cognitive effects of reducing anticholinergic drug burden in a frail elderly population: A randomized controlled trial. JGerontol A Biol Sci Med Sci 2013, 68:271-278.
    • (2013) JGerontol A Biol Sci Med Sci , vol.68 , pp. 271-278
    • Kersten, H.1    Molden, E.2    Tolo, I.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.