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Volumn 21, Issue 8, 2013, Pages 785-793

Measures of anticholinergic drug exposure, serum anticholinergic activity, and all-cause postdischarge mortality in older hospitalized patients with hip fractures

Author keywords

Anticholinergic drug scoring systems; Cognitive impairment; Delirium; Mortality; Older patients; Serum anticholinergic activity

Indexed keywords

CHOLINERGIC RECEPTOR BLOCKING AGENT;

EID: 84884658777     PISSN: 10647481     EISSN: 15457214     Source Type: Journal    
DOI: 10.1016/j.jagp.2013.01.012     Document Type: Article
Times cited : (92)

References (41)
  • 1
    • 77954890671 scopus 로고    scopus 로고
    • Association between prescribing of antimuscarinic drugs and antimuscarinic adverse effects in older people
    • Bostock CV, Soiza RL, Mangoni AA: Association between prescribing of antimuscarinic drugs and antimuscarinic adverse effects in older people. Expert Rev Clin Pharmacol 2010; 3(4): 441-452
    • (2010) Expert Rev Clin Pharmacol , vol.3 , Issue.4 , pp. 441-452
    • Bostock, C.V.1    Soiza, R.L.2    Mangoni, A.A.3
  • 2
    • 0027636902 scopus 로고
    • The problems of anticholinergic adverse effects in older patients
    • Feinberg M: The problems of anticholinergic adverse effects in older patients. Drugs Aging 1993; 3(4): 335-348
    • (1993) Drugs Aging , vol.3 , Issue.4 , pp. 335-348
    • Feinberg, M.1
  • 3
    • 0028919397 scopus 로고
    • Postoperative delirium. A review of 80 primary data-collection studies
    • Dyer CB, Ashton CM, Teasdale TA: Postoperative delirium. A review of 80 primary data-collection studies. Arch Intern Med 1995; 155(5): 461-465
    • (1995) Arch Intern Med , vol.155 , Issue.5 , pp. 461-465
    • Dyer, C.B.1    Ashton, C.M.2    Teasdale, T.A.3
  • 4
    • 0034920302 scopus 로고    scopus 로고
    • Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients
    • Han L, McCusker J, Cole M, et al: Use of medications with anticholinergic effect predicts clinical severity of delirium symptoms in older medical inpatients. Arch Intern Med 2001; 161(8): 1099-1105
    • (2001) Arch Intern Med , vol.161 , Issue.8 , pp. 1099-1105
    • Han, L.1    McCusker, J.2    Cole, M.3
  • 5
    • 41949083073 scopus 로고    scopus 로고
    • The Anticholinergic Risk Scale and anticholinergic adverse effects in older persons
    • Rudolph JL, Salow MJ, Angelini MC, et al: The Anticholinergic Risk Scale and anticholinergic adverse effects in older persons. Arch Intern Med 2008; 168(5): 508-513
    • (2008) Arch Intern Med , vol.168 , Issue.5 , pp. 508-513
    • Rudolph, J.L.1    Salow, M.J.2    Angelini, M.C.3
  • 6
    • 33750720279 scopus 로고    scopus 로고
    • The Anticholinergic Drug Scale as a measure of drug-related anticholinergic burden: Associations with serum anticholinergic activity
    • Carnahan RM, Lund BC, Perry PJ, et al: The Anticholinergic Drug Scale as a measure of drug-related anticholinergic burden: associations with serum anticholinergic activity. J Clin Pharmacol 2006; 46(12): 1481-1486
    • (2006) J Clin Pharmacol , vol.46 , Issue.12 , pp. 1481-1486
    • Carnahan, R.M.1    Lund, B.C.2    Perry, P.J.3
  • 7
    • 34247547047 scopus 로고    scopus 로고
    • A drug burden index to define the functional burden of medications in older people
    • Hilmer SN, Mager DE, Simonsick EM, et al: A drug burden index to define the functional burden of medications in older people. Arch Intern Med 2007; 167(8): 781-787
    • (2007) Arch Intern Med , vol.167 , Issue.8 , pp. 781-787
    • Hilmer, S.N.1    Mager, D.E.2    Simonsick, E.M.3
  • 8
    • 79960941923 scopus 로고    scopus 로고
    • Anticholinergic medication use and cognitive impairment in the older population: The medical research council cognitive function and ageing study [published online ahead of print June 24, 2011]
    • Fox C, Richardson K, Maidment ID, et al: Anticholinergic medication use and cognitive impairment in the older population: the medical research council cognitive function and ageing study [published online ahead of print June 24, 2011]. J Am Geriatr Soc 2011; 59(8): 1477-1483
    • (2011) J Am Geriatr Soc , vol.59 , Issue.8 , pp. 1477-1483
    • Fox, C.1    Richardson, K.2    Maidment, I.D.3
  • 9
    • 72049093999 scopus 로고    scopus 로고
    • Drug burden index score and functional decline in older people
    • Hilmer SN, Mager DE, Simonsick EM, et al: Drug burden index score and functional decline in older people. Am J Med 2009; 122(12): 1142-1149
    • (2009) Am J Med , vol.122 , Issue.12 , pp. 1142-1149
    • Hilmer, S.N.1    Mager, D.E.2    Simonsick, E.M.3
  • 10
    • 80052773815 scopus 로고    scopus 로고
    • Associations between the Anticholinergic Risk Scale score and physical function: Potential implications for adverse outcomes in older hospitalized patients
    • Lowry E, Woodman RJ, Soiza RL, et al: Associations between the Anticholinergic Risk Scale score and physical function: potential implications for adverse outcomes in older hospitalized patients. J Am Med Dir Assoc 2011; 12(8): 565-572
    • (2011) J Am Med Dir Assoc , vol.12 , Issue.8 , pp. 565-572
    • Lowry, E.1    Woodman, R.J.2    Soiza, R.L.3
  • 11
    • 77954428356 scopus 로고    scopus 로고
    • Anti-cholinergic load, health care utilization, and survival in people with advanced cancer: A pilot study
    • Agar M, To T, Plummer J, et al: Anti-cholinergic load, health care utilization, and survival in people with advanced cancer: a pilot study. J Palliat Med 2010; 13(6): 745-752
    • (2010) J Palliat Med , vol.13 , Issue.6 , pp. 745-752
    • Agar, M.1    To, T.2    Plummer, J.3
  • 12
    • 0020373680 scopus 로고
    • Antimuscarinic drugs: Traditional and potential new therapeutic agents
    • Turbanti L, Subissi A, Bramanti G: Antimuscarinic drugs: traditional and potential new therapeutic agents. Pharmacol Res Commun 1982; 14(10): 923-940
    • (1982) Pharmacol Res Commun , vol.14 , Issue.10 , pp. 923-940
    • Turbanti, L.1    Subissi, A.2    Bramanti, G.3
  • 13
    • 0018870462 scopus 로고
    • Serum levels of anticholinergic drugs in treatment of acute extrapyramidal side effects
    • Tune L, Coyle JT: Serum levels of anticholinergic drugs in treatment of acute extrapyramidal side effects. Arch Gen Psychiatry 1980; 37(3): 293-297
    • (1980) Arch Gen Psychiatry , vol.37 , Issue.3 , pp. 293-297
    • Tune, L.1    Coyle, J.T.2
  • 14
    • 48449102484 scopus 로고    scopus 로고
    • Anticholinergic activity of 107 medications commonly used by older adults
    • Chew ML, Mulsant BH, Pollock BG, et al: Anticholinergic activity of 107 medications commonly used by older adults. J Am Geriatr Soc 2008; 56(7): 1333-1341
    • (2008) J Am Geriatr Soc , vol.56 , Issue.7 , pp. 1333-1341
    • Chew, M.L.1    Mulsant, B.H.2    Pollock, B.G.3
  • 15
    • 0036516999 scopus 로고    scopus 로고
    • A critical appraisal of the utility of the serum anticholinergic activity assay in research and clinical practice
    • Carnahan RM, Lund BC, Perry PJ, et al: A critical appraisal of the utility of the serum anticholinergic activity assay in research and clinical practice. Psychopharmacol Bull 2002; 36(2): 24-39
    • (2002) Psychopharmacol Bull , vol.36 , Issue.2 , pp. 24-39
    • Carnahan, R.M.1    Lund, B.C.2    Perry, P.J.3
  • 16
    • 0347319044 scopus 로고    scopus 로고
    • Age-related changes in pharmacokinetics and pharmacodynamics: Basic principles and practical applications
    • Mangoni AA, Jackson SH: Age-related changes in pharmacokinetics and pharmacodynamics: basic principles and practical applications. Br J Clin Pharmacol 2004; 57(1): 6-14
    • (2004) Br J Clin Pharmacol , vol.57 , Issue.1 , pp. 6-14
    • Mangoni, A.A.1    Jackson, S.H.2
  • 17
    • 0024362650 scopus 로고
    • The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): Socio-demographic correlates, reliability, validity and some norms
    • Jorm AF, Jacomb PA: The Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE): socio-demographic correlates, reliability, validity and some norms. Psychol Med 1989; 19(4): 1015-1022
    • (1989) Psychol Med , vol.19 , Issue.4 , pp. 1015-1022
    • Jorm, A.F.1    Jacomb, P.A.2
  • 18
    • 0021013073 scopus 로고
    • Assessing self-maintenance: Activities of daily living, mobility, and instrumental activities of daily living
    • Katz S: Assessing self-maintenance: activities of daily living, mobility, and instrumental activities of daily living. J Am Geriatr Soc 1983; 31(12): 721-727
    • (1983) J Am Geriatr Soc , vol.31 , Issue.12 , pp. 721-727
    • Katz, S.1
  • 19
    • 0025667229 scopus 로고
    • Clarifying confusion: The confusion assessment method. A new method for detection of delirium
    • Inouye SK, van Dyck CH, Alessi CA, et al: Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med 1990; 113(12): 941-948
    • (1990) Ann Intern Med , vol.113 , Issue.12 , pp. 941-948
    • Inouye, S.K.1    Van Dyck, C.H.2    Alessi, C.A.3
  • 20
    • 0038660290 scopus 로고    scopus 로고
    • The Delirium Observation Screening Scale: A screening instrument for delirium
    • Schuurmans MJ, Shortridge-Baggett LM, Duursma SA: The Delirium Observation Screening Scale: a screening instrument for delirium. Res Theory Nurs Pract 2003; 17(1): 31-50
    • (2003) Res Theory Nurs Pract , vol.17 , Issue.1 , pp. 31-50
    • Schuurmans, M.J.1    Shortridge-Baggett, L.M.2    Duursma, S.A.3
  • 21
    • 0027133523 scopus 로고
    • Risk adjustment in outcome assessment: The Charlson comorbidity index
    • D'Hoore W, Sicotte C, Tilquin C: Risk adjustment in outcome assessment: the Charlson comorbidity index. Methods Inf Med 1993; 32(5): 382-387
    • (1993) Methods Inf Med , vol.32 , Issue.5 , pp. 382-387
    • D'Hoore, W.1    Sicotte, C.2    Tilquin, C.3
  • 22
    • 48249104393 scopus 로고    scopus 로고
    • Impact of anticholinergics on the aging brain: A review and practical application
    • Boustani MA, Campbell N, Munger S, et al: Impact of anticholinergics on the aging brain: a review and practical application. Aging Health 2008; 4(3): 311-320
    • (2008) Aging Health , vol.4 , Issue.3 , pp. 311-320
    • Boustani, M.A.1    Campbell, N.2    Munger, S.3
  • 23
    • 0037315114 scopus 로고    scopus 로고
    • Serum anticholinergic activity in a community-based sample of older adults: Relationship with cognitive performance
    • Mulsant BH, Pollock BG, Kirshner M, et al: Serum anticholinergic activity in a community-based sample of older adults: relationship with cognitive performance. Arch Gen Psychiatry 2003; 60(2): 198-203
    • (2003) Arch Gen Psychiatry , vol.60 , Issue.2 , pp. 198-203
    • Mulsant, B.H.1    Pollock, B.G.2    Kirshner, M.3
  • 24
    • 0029071961 scopus 로고
    • Serum anticholinergic activity in hospitalized older persons with delirium: A preliminary study
    • Mach JR Jr, Dysken MW, Kuskowski M, et al: Serum anticholinergic activity in hospitalized older persons with delirium: a preliminary study. J Am Geriatr Soc 1995; 43(5): 491-495
    • (1995) J Am Geriatr Soc , vol.43 , Issue.5 , pp. 491-495
    • Mach Jr., J.R.1    Dysken, M.W.2    Kuskowski, M.3
  • 25
    • 69949103030 scopus 로고    scopus 로고
    • The cognitive cost of anticholinergic burden: Decreased response to cognitive training in schizophrenia
    • Vinogradov S, Fisher M, Warm H, et al: The cognitive cost of anticholinergic burden: decreased response to cognitive training in schizophrenia. Am J Psychiatry 2009; 166(9): 1055-1062
    • (2009) Am J Psychiatry , vol.166 , Issue.9 , pp. 1055-1062
    • Vinogradov, S.1    Fisher, M.2    Warm, H.3
  • 26
    • 84903070020 scopus 로고    scopus 로고
    • Serum anticholinergic activity and cognition in patients with moderate-to-severe dementia
    • Chew ML, Mulsant BH, Pollock BG: Serum anticholinergic activity and cognition in patients with moderate-to-severe dementia. Am J Geriatr Psychiatry 2005; 13(6): 535-538
    • (2005) Am J Geriatr Psychiatry , vol.13 , Issue.6 , pp. 535-538
    • Chew, M.L.1    Mulsant, B.H.2    Pollock, B.G.3
  • 27
    • 34047152829 scopus 로고    scopus 로고
    • Serum anticholinergic activity and motor performance in elderly persons
    • Nebes RD, Pollock BG, Halligan EM, et al: Serum anticholinergic activity and motor performance in elderly persons. J Gerontol A Biol Sci Med Sci 2007; 62(1): 83-85
    • (2007) J Gerontol A Biol Sci Med Sci , vol.62 , Issue.1 , pp. 83-85
    • Nebes, R.D.1    Pollock, B.G.2    Halligan, E.M.3
  • 28
    • 34047110667 scopus 로고    scopus 로고
    • Significant correlation between plasma and CSF anticholinergic activity in presurgical patients
    • Plaschke K, Thomas C, Engelhardt R, et al: Significant correlation between plasma and CSF anticholinergic activity in presurgical patients. Neurosci Lett 2007; 417(1): 16-20
    • (2007) Neurosci Lett , vol.417 , Issue.1 , pp. 16-20
    • Plaschke, K.1    Thomas, C.2    Engelhardt, R.3
  • 29
    • 69549124151 scopus 로고    scopus 로고
    • Flaws in the serum anticholinergic activity assay: Implications for the study of delirium
    • Cox EA, Kwatra SG, Shetty S, et al: Flaws in the serum anticholinergic activity assay: implications for the study of delirium. J Am Geriatr Soc 2009; 57(9): 1707-1708
    • (2009) J Am Geriatr Soc , vol.57 , Issue.9 , pp. 1707-1708
    • Cox, E.A.1    Kwatra, S.G.2    Shetty, S.3
  • 30
    • 0034982685 scopus 로고    scopus 로고
    • Endogenous anticholinergic substances may exist during acute illness in elderly medical patients
    • Flacker JM, Wei JY: Endogenous anticholinergic substances may exist during acute illness in elderly medical patients. J Gerontol A Biol Sci Med Sci 2001; 56(6):M353-M355
    • (2001) J Gerontol A Biol Sci Med Sci , vol.56 , Issue.6
    • Flacker, J.M.1    Wei, J.Y.2
  • 31
    • 0032935345 scopus 로고    scopus 로고
    • Serum anticholinergic activity changes with acute illness in elderly medical patients
    • Flacker JM, Lipsitz LA: Serum anticholinergic activity changes with acute illness in elderly medical patients. J Gerontol A Biol Sci Med Sci 1999; 54(1):M12-M16
    • (1999) J Gerontol A Biol Sci Med Sci , vol.54 , Issue.1
    • Flacker, J.M.1    Lipsitz, L.A.2
  • 32
    • 34250347319 scopus 로고    scopus 로고
    • Serum anticholinergic activity in patients following cardiac surgery and healthy individuals following amitriptyline application
    • Brecht S, Reiff J, Vock U, et al: Serum anticholinergic activity in patients following cardiac surgery and healthy individuals following amitriptyline application. Methods Find Exp Clin Pharmacol 2007; 29(3): 223-230
    • (2007) Methods Find Exp Clin Pharmacol , vol.29 , Issue.3 , pp. 223-230
    • Brecht, S.1    Reiff, J.2    Vock, U.3
  • 33
    • 80052770923 scopus 로고    scopus 로고
    • Assessing the adverse effects of antimuscarinic drugs in older patients: Which way forward?
    • Mangoni AA: Assessing the adverse effects of antimuscarinic drugs in older patients: which way forward? Expert Rev Clin Pharmacol 2011; 4(5): 531-533
    • (2011) Expert Rev Clin Pharmacol , vol.4 , Issue.5 , pp. 531-533
    • Mangoni, A.A.1
  • 34
    • 79955982494 scopus 로고    scopus 로고
    • Associations between drug burden index and falls in older people in residential aged care
    • Wilson NM, Hilmer SN, March LM, et al: Associations between drug burden index and falls in older people in residential aged care. J Am Geriatr Soc 2011; 59(5): 875-880
    • (2011) J Am Geriatr Soc , vol.59 , Issue.5 , pp. 875-880
    • Wilson, N.M.1    Hilmer, S.N.2    March, L.M.3
  • 35
    • 84870458315 scopus 로고    scopus 로고
    • Drug Burden Index, physical function, and adverse outcomes in older hospitalized patients
    • [published online ahead of print December 13, 2011]., DOI: 10.1177/0091270011421489
    • Lowry E, Woodman RJ, Soiza RL, et al: Drug Burden Index, physical function, and adverse outcomes in older hospitalized patients [published online ahead of print December 13, 2011]. J Clin Pharmacol DOI: 10.1177/0091270011421489
    • J Clin Pharmacol
    • Lowry, E.1    Woodman, R.J.2    Soiza, R.L.3
  • 36
    • 27644507352 scopus 로고    scopus 로고
    • Serum anticholinergic activity, white matter hyperintensities, and cognitive performance
    • Nebes RD, Pollock BG, Meltzer CC, et al: Serum anticholinergic activity, white matter hyperintensities, and cognitive performance. Neurology 2005; 65(9): 1487-1489
    • (2005) Neurology , vol.65 , Issue.9 , pp. 1487-1489
    • Nebes, R.D.1    Pollock, B.G.2    Meltzer, C.C.3
  • 37
    • 78651230387 scopus 로고    scopus 로고
    • Influence of anticholinergic activity in serum on clinical symptoms of Alzheimer's disease
    • Hori K, Konishi K, Watanabe K, et al: Influence of anticholinergic activity in serum on clinical symptoms of Alzheimer's disease. Neuropsychobiology 2011; 63(3): 147-153
    • (2011) Neuropsychobiology , vol.63 , Issue.3 , pp. 147-153
    • Hori, K.1    Konishi, K.2    Watanabe, K.3
  • 38
    • 78149305187 scopus 로고    scopus 로고
    • Increased cortisol levels and anticholinergic activity in cognitively unimpaired patients
    • Plaschke K, Kopitz J, Mattern J, et al: Increased cortisol levels and anticholinergic activity in cognitively unimpaired patients. J Neuropsychiatry Clin Neurosci 2010; 22(4): 433-441
    • (2010) J Neuropsychiatry Clin Neurosci , vol.22 , Issue.4 , pp. 433-441
    • Plaschke, K.1    Kopitz, J.2    Mattern, J.3
  • 39
    • 37549045307 scopus 로고    scopus 로고
    • Predictive value of six risk scores for outcome after surgical repair of hip fracture in elderly patients
    • Burgos E, Gomez-Arnau JI, Diez R, et al: Predictive value of six risk scores for outcome after surgical repair of hip fracture in elderly patients. Acta Anaesthesiol Scand 2008; 52(1): 125-131
    • (2008) Acta Anaesthesiol Scand , vol.52 , Issue.1 , pp. 125-131
    • Burgos, E.1    Gomez-Arnau, J.I.2    Diez, R.3
  • 40
    • 33748639911 scopus 로고    scopus 로고
    • Mortality within 1 year after hip fracture surgical repair in the elderly according to postoperative period: A probabilistic record linkage study in Brazil
    • Vidal EI, Coeli CM, Pinheiro RS, et al: Mortality within 1 year after hip fracture surgical repair in the elderly according to postoperative period: a probabilistic record linkage study in Brazil. Osteoporos Int 2006; 17(10): 1569-1576
    • (2006) Osteoporos Int , vol.17 , Issue.10 , pp. 1569-1576
    • Vidal, E.I.1    Coeli, C.M.2    Pinheiro, R.S.3
  • 41
    • 79952911444 scopus 로고    scopus 로고
    • Nottingham Hip Fracture Score as a predictor of one year mortality in patients undergoing surgical repair of fractured neck of femur
    • Wiles MD, Moran CG, Sahota O, et al: Nottingham Hip Fracture Score as a predictor of one year mortality in patients undergoing surgical repair of fractured neck of femur. Br J Anaesth 2011; 106(4): 501-504
    • (2011) Br J Anaesth , vol.106 , Issue.4 , pp. 501-504
    • Wiles, M.D.1    Moran, C.G.2    Sahota, O.3


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