Anemia Status, Hemoglobin Concentration, and Mortality in Nursing Home Older Residents

Journal of the American Medical Directors Association

Volumn 8, Issue 5, 2007, Pages 322-327

  Landi, Francesco ^a   Russo, Andrea ^a   Danese, Paola ^a   Liperoti, Rosa ^a   Barillaro, Christian ^a   Bernabei, Roberto ^a   Onder, Graziano ^a  

^a CATHOLIC UNIVERSITY   (Italy)

Author keywords

anemia; frail elderly; Hemoglobin concentration; mortality

Indexed keywords

CREATININE; HEMOGLOBIN;

AGED; ANEMIA; ARTICLE; BODY MASS; CANCER; COGNITIVE DEFECT; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; DECUBITUS; FEMALE; FOLLOW UP; FRAIL ELDERLY; FUNCTIONAL STATUS; HAZARD RATIO; HEMOGLOBIN DETERMINATION; HUMAN; MALE; MORBIDITY; MORTALITY; NURSING HOME; NURSING HOME PATIENT; OUTCOME ASSESSMENT; RISK ASSESSMENT; SAMPLE SIZE; STATISTICAL SIGNIFICANCE; STROKE; SURVIVAL;

EID: 34249931170     PISSN: 15258610     EISSN: 15389375     Source Type: Journal    
DOI: 10.1016/j.jamda.2007.01.028     Document Type: Article

References (28)

1. World Health Organization. Nutritional Anaemias. Report of a WHO scientific group (Technical Report Series no. 405) (1968), World Health Organization, Geneva
2. Salive M.E., Cornoni-Huntley J., Guralnik J.M., et al. Anemia and haemoglobin levels in older persons: Relationship with age, gender, and health status. J Am Geriatr Soc 40 (1992) 489-496
3. Joosten E., Pelemans W., Hiele M., et al. Prevalence and causes of anaemia in a geriatric hospitalized population. Gerontology 38 (1992) 111-117
4. Ania B.J., Suman V.J., Fairbanks V.F., et al. Incidence of anemia in older people: An epidemiologic study in a well defined population. J Am Geriatr Soc 45 (1997) 825-831
5. Izaks G.J., Westendorp R.G., and Knook D.L. The definition of anemia in older persons. JAMA 281 (1999) 1714-1717
6. Nissenson A.R., Goodnough L.T., and Dubois R.W. Anemia: not just an innocent bystander?. Arch Intern Med 163 (2003) 1400-1404
7. Zakai N.A., Katz R., Hirsch C., et al. A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort-the Cardiovascular Health Study. Arch Intern Med 165 (2005) 2214-2220
8. Fuchs Z., Blumstein T., Novikov I., et al. Morbidity, comorbidity, and their association with disability among community-dwelling oldest-old in Israel. J Gerontol Med Sci 53A (1998) M447-M455
9. Penninx B.W.J.H., Pahor M., Cesari M., et al. Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc 52 (2004) 1811-1816
10. Penninx B.W.J.H., Guralnik J.M., Onder G., Ferrucci L., Wallace R.B., and Pahor M. Anemia and decline in physical performance among older persons. Am J Med 115 (2003) 104-110
11. Boogaerts M., Coiffier B., and Kainz C. Impact of epoetin beta on quality of life in patients with malignant disease. Br J Cancer 88 (2003) 988-995
12. Guralnik J.M., Eisenstaedt R.S., Ferrucci L., Klein H.G., and Woodman R.C. Prevalence of anemia in persons 65 years and older in the United States: Evidence for a high rate of unexplained anemia. Blood 104 (2004) 2263-2268
13. Chaves P.H., Ashar B., Guralnik J.M., and Fried L.P. Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women: Should the criteria currently used to define anemia in older people be reevaluated?. J Am Geriatr Soc 50 (2002) 1257-1264
14. Oliver D.P., Porock D., and Zweig S. End-of-life care in US nursing homes: A review of the evidence. J Am Med Dir Assoc 3 (2005) S21-S30
15. Dharmarajan T.S., Avula S., and Norkus E.P. Anemia increases risk for falls in hospitalized older adults: An evaluation of falls in 362 hospitalized ambulatory, long-term care, and community patients. J Am Med Dir Assoc 5 (2006) 287-293
16. Gambassi G., Landi F., Peng L., et al. Validity of diagnostic and drug data in standardized nursing home resident assessments: Potential for geriatric pharmacoepidemiology. Med Care 36 (1998) 167-179
17. Morris J., Hawes C., Murphy K., Nonemaker S., Phillips C., Fries B., and Mor V. Minimum data set plus training manual (1991), Eliot Press, Natick, MA
18. Bernabei R., Gambassi G., Lapane K., et al. Characteristics of the SAGE database: A new resource for research on outcomes in long-term care. J Gerontol A Biol Sci Med Sci 54 (1999) M25-M33
19. Morris J.N., Fries B.E., and Meher D.R. MDS Cognitive Performance Scale. J Gerontol 49 (1994) M174-M182
20. Landi F., Tua E., Onder G., et al. Minimum data set for home care: A valid instrument to assess frail older people living in the community. Med Care 38 12 (2000) 1184-1190
21. Artz A. Outcomes of anemia in the elderly: What we know. J Am Med Dir Assoc 4 (2005) S1-S4
22. Tangalos E.G., Hoggard J.G., Murray A.M., and Thomas D.R. Treatment of kidney disease and anemia in elderly, long-term care residents. J Am Med Dir Assoc 5 (2004) H1-H6
23. Spivak J.L. Anemia in the elderly. Time for new blood in old vessels?. Arch Intern Med 165 (2005) 1187-1190
24. Kikuchi M., Inagaki T., and Shinagawa N. Five-year survival of older people with anemia: Variation with hemoglobin concentration. J Am Geriatr Soc 49 (2001) 1226-1228
25. Chaves P.H.M., Xue Q.L., Guralnik J.M., Ferrucci L., Volpato S., and Fried L.P. What constitutes normal hemoglobin concentration in community-dwelling disabled older women?. J Am Geriatr Soc 52 (2004) 1811-1816
26. Lipschitz D.A., Mitchell C.O., and Thompson C. The anemia of senescence. Am J Hematol 11 (1981) 47-54
27. van Dijk P.T.M., Mehr D.R., Ooms M.E., et al. Comorbidity and 1-year mortality risks in nursing home residents. J Am Geriatr Soc 53 (2005) 660-665
28. Dharmarajan T., and Norkus E.P. Mild anemia and the risk of falls in older adults from nursing homes and the community. J Am Med Dir Assoc 5 (2004) 395-400