Adiponectin alleviates genioglossal mitochondrial dysfunction in rats exposed to intermittent hypoxia

PLoS ONE

Volumn 9, Issue 10, 2014, Pages

  Huang, Hanpeng ^a   Jiang, Xiufeng ^b   Dong, Yanbin ^c   Zhang, Xiaofeng ^c   Ding, Ning ^c   Liu, Jiannan ^d   Hutchinson, Sean Z ^e   Lu, Gan ^d   Zhang, Xilong ^c  

^a AFFILIATED HOSPITAL OF JIANGSU UNIVERSITY   (China)

^b WUXI PEOPLE S HOSPITAL AFFILIATED TO NANJING MEDICAL UNIVERSITY   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

^d Department of Respiratory Diseases Jangsu Geriatric Hospital   (China)

^e UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ADIPONECTIN; CYTOCHROME C; CYTOCHROME C OXIDASE; DNA GLYCOSYLTRANSFERASE; ESTROGEN RELATED RECEPTOR ALPHA; NUCLEAR RESPIRATORY FACTOR 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PROTEIN KINASE LKB1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE);

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BIOGENESIS; CELL FUNCTION; CELL ULTRASTRUCTURE; CHRONIC INTERMITTENT HYPOXIA; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENIOGLOSSAL INJURY; GENIOGLOSSUS; HISTOPATHOLOGY; MALE; MITOCHONDRION; MUSCLE; MUSCLE CELL; NONHUMAN; PATHOPHYSIOLOGY; RAT; SARCOLEMMA; SIGNAL TRANSDUCTION; SLEEP DISORDERED BREATHING; ANIMAL; ANOXIA; COMPLICATION; DRUG EFFECTS; METABOLISM; PATHOLOGY;

RATTUS;

ADIPONECTIN; ANIMALS; ANOXIA; MALE; MITOCHONDRIA; MUSCLES; RATS; SIGNAL TRANSDUCTION;

EID: 84908191410     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0109284     Document Type: Article

References (37)

1. Zhang XL, Yin KS, Mao H, Wang H., Yang Y (2004) Serum adiponectin level in patients with obstructive sleep apnea hypopnea syndrome. Chin Med J (Engl) 117: 1603-1606.
2. Kanbay A, Kokturk O, Ciftci T.U., Tavil Y., Bukan N (2008) Comparison of serum adiponectin and tumor necrosis factor-alpha levels between patients with and without obstructive sleep apnea syndrome. Respiration 76: 324-330.
3. Huang H, Zhang X, Ding N., Li Q, Min Y, et al. (2012) Effects of chronic intermittent hypoxia on genioglossus in rats. Sleep Breath 16: 505-510.
4. Shehzad A, Iqbal W, Shehzad O., Lee YS (2012) Adiponectin: regulation of its production and its role in human diseases. Hormones (Athens) 11: 8-20.
5. Yamauchi T, Nio Y, Maki T., Kobayashi M, Takazawa T, et al. (2007) Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions. Nat Med 13: 332-339.
6. Ohashi K, Ouchi N, Matsuzawa Y (2012) Anti-inflammatory and anti-atherogenic properties of adiponectin. Biochimie 94: 2137-2142.
7. Arita Y, Kihara S, Ouchi N., Takahashi M, Maeda K, et al. (1999) Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257: 79-83.
8. Illan-Gomez F, Gonzalvez-Ortega M, Orea-Soler I, Alcaraz-Tafalla MS, Aragon-Alonso A, et al. (2012) Obesity and inflammation: change in adiponectin, C-reactive protein, tumour necrosis factor-alpha and interleukin-6 after bariatric surgery. Obes Surg 22: 950-955.
9. Civitarese AE, Ukropcova B, Carling S., Hulver M, DeFronzo RA, et al. (2006) Role of adiponectin in human skeletal muscle bioenergetics. Cell Metab 4: 75-87.
10. Qiao L, Kinney B, Yoo H.S., Lee B., Schaack J, et al. (2012) Adiponectin increases skeletal muscle mitochondrial biogenesis by suppressing mitogen-activated protein kinase phosphatase-1. Diabetes 61: 1463-1470.
11. Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K., Nakagawa T, et al. (2010) Adiponectin and AdipoR1 regulate PGC-1alpha and mitochondria by Ca(2+) and AMPK/SIRT1. Nature 464: 1313-1319.
12. Zhu XD, Zhuang Y, Ben J.J., Qian LL, Huang HP, et al. (2011) Caveolae-dependent endocytosis is required for class A macrophage scavenger receptor-mediated apoptosis in macrophages. J Biol Chem 286: 8231-8239.
13. Seligman AM, Karnovsky MJ, Wasserkrug H.L., Hanker JS (1968) Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB). J Cell Biol 38: 1-14.
14. Nachlas MM, Tsou KC, De Souza E, Cheng CS, Seligman AM (1957) Cytochemical demonstration of succinic dehydrogenase by the use of a new p-nitrophenyl substituted ditetrazole. J Histochem Cytochem 5: 420-436.
15. Carrera M, Barbe F, Sauleda J., Tomas M, Gomez C, et al. (1999) Patients with obstructive sleep apnea exhibit genioglossus dysfunction that is normalized after treatment with continuous positive airway pressure. Am J Respir Crit Care Med 159: 1960-1966.
16. Trinder J, Jordan AS (2011) Activation of the upper airway dilator muscle genioglossus during sleep is largely dependent on an interaction between chemical drive and mechanoreceptor feedback. Sleep 34: 983-984.
17. Young T, Palta M, Dempsey J., Skatrud J, Weber S, et al. (1993) The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328: 1230-1235.
18. Jordan AS, White DP, Owens R.L., Eckert DJ, Rahangdale S, et al. (2010) The effect of increased genioglossus activity and end-expiratory lung volume on pharyngeal collapse. J Appl Physiol 109: 469-475.
19. Bailey EF (2011) Activities of human genioglossus motor units. Respir Physiol Neurobiol 179: 14-22.
20. Oliven A, Tov N, Geitini L., Steinfeld U, Oliven R, et al. (2007) Effect of genioglossus contraction on pharyngeal lumen and airflow in sleep apnoea patients. Eur Respir J 30: 748-758.
21. Bonnard C, Durand A, Peyrol S., Chanseaume E, Chauvin MA, et al. (2008) Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J Clin Invest 118: 789-800.
22. Li L, Muhlfeld C, Niemann B., Pan R, Li R, et al. (2011) Mitochondrial biogenesis and PGC-1alpha deacetylation by chronic treadmill exercise: differential response in cardiac and skeletal muscle. Basic Res Cardiol 106: 1221-1234.
23. Kong X, Wang R, Xue Y., Liu X, Zhang H, et al. (2010) Sirtuin 3, a new target of PGC-1alpha, plays an important role in the suppression of ROS and mitochondrial biogenesis. PLoS One 5: e11707.
24. Scarpulla RC (2011) Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network. Biochim Biophys Acta 1813: 1269-1278.
25. Douglas RM, Ryu J, Kanaan A., Del Carmen Rivero M, Dugan LL, et al. (2010) Neuronal death during combined intermittent hypoxia/hypercapnia is due to mitochondrial dysfunction. Am J Physiol Cell Physiol 298: C1594-1602.
26. Lee SD, Kuo WW, Lin J.A., Chu YF, Wang CK, et al. (2007) Effects of long-term intermittent hypoxia on mitochondrial and Fas death receptor dependent apoptotic pathways in rat hearts. Int J Cardiol 116: 348-356.
27. Sutlive TG, Shall MS, McClung J.R., Goldberg SJ (2000) Contractile properties of the tongue's genioglossus muscle and motor units in the rat. Muscle Nerve 23: 416-425.
28. Kadi F, Karlsson C, Larsson B., Eriksson J, Larval M, et al. (2002) The effects of physical activity and estrogen treatment on rat fast and slow skeletal muscles following ovariectomy. J Muscle Res Cell Motil 23: 335-339.
29. Boyd JH, Petrof BJ, Hamid Q, Fraser R., Kimoff RJ (2004) Upper airway muscle inflammation and denervation changes in obstructive sleep apnea. Am J Respir Crit Care Med 170: 541-546.
30. Lin J, Wu H, Tarr P.T., Zhang CY, Wu Z, et al. (2002) Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature 418: 797-801.
31. Hardie DG, Ross FA, Hawley SA (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13: 251-262.
32. Fritah A, Steel JH, Parker N, Nikolopoulou E., Christian M, et al. (2012) Absence of RIP140 reveals a pathway regulating glut4-dependent glucose uptake in oxidative skeletal muscle through UCP1-mediated activation of AMPK. PLoS One 7: e32520.
33. Bergeron R, Ren JM, Cadman K.S., Moore IK, Perret P, et al. (2001) Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis. Am J Physiol Endocrinol Metab 281: E1340-1346.
34. Ix JH, Sharma K (2010) Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK. J Am Soc Nephrol 21: 406-412.
35. Bonneau GA, Pedrozo WR, Berg G.(2013) Adiponectin and waist circumference as predictors of insulin-resistance in women. Diabetes Metab Syndr. 8(1): 3-7.
36. de Almeida AR, Monte-Alegre S, Zanini M.B., Souza AL, Etchebehere M, et al.(2014) Association between prehypertension, metabolic and inflammatory markers, decreased adiponectin and enhanced insulinemia in obese subjects. Nutr Metab (Lond). 11: 25.
37. Miniello VL, Faienza MF, Scicchitano P, Cortese F., Gesualdo M, et al. (2014) Insulin resistance and endothelial function in children and adolescents. Int J Cardiol. 174: 343-347.