-
1
-
-
0033533596
-
Diabetes and cardiovascular disease: A statement for healthcare professionals from the American heart association
-
Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, et al. (1999) Diabetes and cardiovascular disease: a statement for healthcare professionals from the American Heart Association. Circulation 100: 1134-1146.
-
(1999)
Circulation
, vol.100
, pp. 1134-1146
-
-
Grundy, S.M.1
Benjamin, I.J.2
Burke, G.L.3
Chait, A.4
Eckel, R.H.5
-
2
-
-
29244462334
-
Insulin signaling and the regulation of glucose transport
-
Chang L, Chiang SH, Saltiel AR (2004) Insulin signaling and the regulation of glucose transport. Mol Med 10: 65-71.
-
(2004)
Mol Med
, vol.10
, pp. 65-71
-
-
Chang, L.1
Chiang, S.H.2
Saltiel, A.R.3
-
3
-
-
0036434431
-
Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
-
Khan AH, Pessin JE (2002) Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 45: 1475-1483.
-
(2002)
Diabetologia
, vol.45
, pp. 1475-1483
-
-
Khan, A.H.1
Pessin, J.E.2
-
4
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
de Souza CJ, Eckhardt M, Gagen K, Dong M, Chen W, et al. (2001) Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes 50: 1863-1871.
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
De Souza, C.J.1
Eckhardt, M.2
Gagen, K.3
Dong, M.4
Chen, W.5
-
5
-
-
33845677575
-
Rosiglitazone inhibits mouse liver regeneration
-
Turmelle YP, Shikapwashya O, Tu S, Hruz PW, Yan Q, et al. (2006) Rosiglitazone inhibits mouse liver regeneration. FASEB J 20: 2609-2611.
-
(2006)
FASEB J
, vol.20
, pp. 2609-2611
-
-
Turmelle, Y.P.1
Shikapwashya, O.2
Tu, S.3
Hruz, P.W.4
Yan, Q.5
-
6
-
-
0347719481
-
Bone is a target for the antidiabetic compound rosiglitazone
-
Rzonca SO, Suva LJ, Gaddy D, Montague DC, Lecka-Czernik B (2004) Bone is a target for the antidiabetic compound rosiglitazone. Endocrinology 145: 401-406.
-
(2004)
Endocrinology
, vol.145
, pp. 401-406
-
-
Rzonca, S.O.1
Suva, L.J.2
Gaddy, D.3
Montague, D.C.4
Lecka-Czernik, B.5
-
7
-
-
38949149637
-
Ursolic acid: An anti- and pro-inflammatory triterpenoid
-
Ikeda Y, Murakami A, Ohigashi H (2008) Ursolic acid: an anti- and pro-inflammatory triterpenoid. Mol Nutr Food Res 52: 26-42.
-
(2008)
Mol Nutr Food Res
, vol.52
, pp. 26-42
-
-
Ikeda, Y.1
Murakami, A.2
Ohigashi, H.3
-
8
-
-
23044440041
-
Oleanolic acid and ursolic acid: Research perspectives
-
Liu J (2005) Oleanolic acid and ursolic acid: research perspectives. J Ethnopharmacol 100: 92-94.
-
(2005)
J Ethnopharmacol
, vol.100
, pp. 92-94
-
-
Liu, J.1
-
9
-
-
31044449046
-
Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in cornelian cherry (Cornus mas)
-
Jayaprakasam B, Olson LK, Schutzki RE, Tai MH, Nair MG (2006) Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas). J Agric Food Chem 54: 243-248.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 243-248
-
-
Jayaprakasam, B.1
Olson, L.K.2
Schutzki, R.E.3
Tai, M.H.4
Nair, M.G.5
-
10
-
-
80755175244
-
Ursolic acid, a pentacyclic triterpene from sambucus australis, prevents abdominal adiposity in mice fed a high-fat diet
-
Rao VS, de Melo CL, Queiroz MG, Lemos TL, Menezes DB, et al. (2011) Ursolic acid, a pentacyclic triterpene from Sambucus australis, prevents abdominal adiposity in mice fed a high-fat diet. J Med Food 14: 1375-1382.
-
(2011)
J Med Food
, vol.14
, pp. 1375-1382
-
-
Rao, V.S.1
De Melo, C.L.2
Queiroz, M.G.3
Lemos, T.L.4
Menezes, D.B.5
-
11
-
-
68649103280
-
Anti-lipase and lipolytic activities of ursolic acid isolated from the roots of actinidia arguta
-
Kim J, Jang DS, Kim H, Kim JS (2009) Anti-lipase and lipolytic activities of ursolic acid isolated from the roots of Actinidia arguta. Arch Pharm Res 32: 983-987.
-
(2009)
Arch Pharm Res
, vol.32
, pp. 983-987
-
-
Kim, J.1
Jang, D.S.2
Kim, H.3
Kim, J.S.4
-
12
-
-
78349294211
-
Ursolic acid stimulates lipolysis in primary-cultured rat adipocytes
-
Li Y, Kang Z, Li S, Kong T, Liu X, et al. (2010) Ursolic acid stimulates lipolysis in primary-cultured rat adipocytes. Mol Nutr Food Res 54: 1609-1617.
-
(2010)
Mol Nutr Food Res
, vol.54
, pp. 1609-1617
-
-
Li, Y.1
Kang, Z.2
Li, S.3
Kong, T.4
Liu, X.5
-
13
-
-
84880770584
-
Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1/AMPK pathway
-
He Y, Li Y, Zhao T, Wang Y, Sun C (2013) Ursolic acid inhibits adipogenesis in 3T3-L1 adipocytes through LKB1/AMPK pathway. PLoS One 8: e70135.
-
(2013)
PLoS One
, vol.8
-
-
He, Y.1
Li, Y.2
Zhao, T.3
Wang, Y.4
Sun, C.5
-
14
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
15
-
-
77949433071
-
Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice
-
Jang SM, Kim MJ, Choi MS, Kwon EY, Lee MK (2010) Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice. Metabolism 59: 512-519.
-
(2010)
Metabolism
, vol.59
, pp. 512-519
-
-
Jang, S.M.1
Kim, M.J.2
Choi, M.S.3
Kwon, E.Y.4
Lee, M.K.5
-
16
-
-
58149464690
-
Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet
-
Jang SM, Yee ST, Choi J, Choi MS, Do GM, et al. (2009) Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet. Int Immunopharmacol 9: 113-119.
-
(2009)
Int Immunopharmacol
, vol.9
, pp. 113-119
-
-
Jang, S.M.1
Yee, S.T.2
Choi, J.3
Choi, M.S.4
Do, G.M.5
-
17
-
-
83055184172
-
Anti-diabetic potential of ursolic acid stearoyl glucoside: A new triterpenic gycosidic ester from lantana camara
-
Kazmi I, Rahman M, Afzal M, Gupta G, Saleem S, et al. (2012) Anti-diabetic potential of ursolic acid stearoyl glucoside: a new triterpenic gycosidic ester from Lantana camara. Fitoterapia 83: 142-146.
-
(2012)
Fitoterapia
, vol.83
, pp. 142-146
-
-
Kazmi, I.1
Rahman, M.2
Afzal, M.3
Gupta, G.4
Saleem, S.5
-
18
-
-
79958072409
-
MRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass
-
Kunkel SD, Suneja M, Ebert SM, Bongers KS, Fox DK, et al. (2011) mRNA expression signatures of human skeletal muscle atrophy identify a natural compound that increases muscle mass. Cell Metab 13: 627-638.
-
(2011)
Cell Metab
, vol.13
, pp. 627-638
-
-
Kunkel, S.D.1
Suneja, M.2
Ebert, S.M.3
Bongers, K.S.4
Fox, D.K.5
-
19
-
-
78149466792
-
Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice
-
Lee J, Yee ST, Kim JJ, Choi MS, Kwon EY, et al. (2010) Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice. Chem Biol Interact 188: 635-642.
-
(2010)
Chem Biol Interact
, vol.188
, pp. 635-642
-
-
Lee, J.1
Yee, S.T.2
Kim, J.J.3
Choi, M.S.4
Kwon, E.Y.5
-
20
-
-
84862665187
-
Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease
-
Kunkel SD, Elmore CJ, Bongers KS, Ebert SM, Fox DK, et al. (2012) Ursolic acid increases skeletal muscle and brown fat and decreases diet-induced obesity, glucose intolerance and fatty liver disease. PLoS One 7: e39332.
-
(2012)
PLoS One
, vol.7
-
-
Kunkel, S.D.1
Elmore, C.J.2
Bongers, K.S.3
Ebert, S.M.4
Fox, D.K.5
-
21
-
-
33748882713
-
Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake
-
Zhang W, Hong D, Zhou Y, Zhang Y, Shen Q, et al. (2006) Ursolic acid and its derivative inhibit protein tyrosine phosphatase 1B, enhancing insulin receptor phosphorylation and stimulating glucose uptake. Biochim Biophys Acta 1760: 1505-1512.
-
(2006)
Biochim Biophys Acta
, vol.1760
, pp. 1505-1512
-
-
Zhang, W.1
Hong, D.2
Zhou, Y.3
Zhang, Y.4
Shen, Q.5
-
22
-
-
77953884960
-
Ursolic acid and luteolin-7-glucoside improve lipid profiles and increase liver glycogen content through glycogen synthase kinase-3
-
Azevedo MF, Camsari C, Sa CM, Lima CF, Fernandes-Ferreira M, et al. (2010) Ursolic acid and luteolin-7-glucoside improve lipid profiles and increase liver glycogen content through glycogen synthase kinase-3. Phytother Res 24 Suppl 2: S220-224.
-
(2010)
Phytother Res
, vol.24
, pp. S220-224
-
-
Azevedo, M.F.1
Camsari, C.2
Sa, C.M.3
Lima, C.F.4
Fernandes-Ferreira, M.5
-
23
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen ED, Spiegelman BM (2006) Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444: 847-853.
-
(2006)
Nature
, vol.444
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
24
-
-
84879606038
-
Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes
-
He Y, Li Y, Zhang S, Perry B, Zhao T, et al. (2013) Radicicol, a heat shock protein 90 inhibitor, inhibits differentiation and adipogenesis in 3T3-L1 preadipocytes. Biochem Biophys Res Commun 436: 169-174.
-
(2013)
Biochem Biophys Res Commun
, vol.436
, pp. 169-174
-
-
He, Y.1
Li, Y.2
Zhang, S.3
Perry, B.4
Zhao, T.5
-
26
-
-
84897382346
-
Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats
-
Li S, Liao X, Meng F, Wang Y, Sun Z, et al. (2014) Therapeutic role of ursolic acid on ameliorating hepatic steatosis and improving metabolic disorders in high-fat diet-induced non-alcoholic fatty liver disease rats. PLoS One 9: e86724.
-
(2014)
PLoS One
, vol.9
-
-
Li, S.1
Liao, X.2
Meng, F.3
Wang, Y.4
Sun, Z.5
-
27
-
-
18244382304
-
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
-
Donnelly KL, Smith CI, Schwarzenberg SJ, Jessurun J, Boldt MD, et al. (2005) Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 115: 1343-1351.
-
(2005)
J Clin Invest
, vol.115
, pp. 1343-1351
-
-
Donnelly, K.L.1
Smith, C.I.2
Schwarzenberg, S.J.3
Jessurun, J.4
Boldt, M.D.5
-
28
-
-
1842454705
-
Adipose tissue and adipokines: For better or worse
-
Guerre-Millo M (2004) Adipose tissue and adipokines: for better or worse. Diabetes Metab 30: 13-19.
-
(2004)
Diabetes Metab
, vol.30
, pp. 13-19
-
-
Guerre-Millo, M.1
-
29
-
-
33646161443
-
Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
-
Haukeland JW, Damas JK, Konopski Z, Loberg EM, Haaland T, et al. (2006) Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2. J Hepatol 44: 1167-1174.
-
(2006)
J Hepatol
, vol.44
, pp. 1167-1174
-
-
Haukeland, J.W.1
Damas, J.K.2
Konopski, Z.3
Loberg, E.M.4
Haaland, T.5
-
30
-
-
33644825288
-
Increased serum resistin in nonalcoholic fatty liver disease is related to liver disease severity and not to insulin resistance
-
Pagano C, Soardo G, Pilon C, Milocco C, Basan L, et al. (2006) Increased serum resistin in nonalcoholic fatty liver disease is related to liver disease severity and not to insulin resistance. J Clin Endocrinol Metab 91: 1081-1086.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 1081-1086
-
-
Pagano, C.1
Soardo, G.2
Pilon, C.3
Milocco, C.4
Basan, L.5
-
31
-
-
0035825643
-
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver
-
Abel ED, Peroni O, Kim JK, Kim YB, Boss O, et al. (2001) Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver. Nature 409: 729-733.
-
(2001)
Nature
, vol.409
, pp. 729-733
-
-
Abel, E.D.1
Peroni, O.2
Kim, J.K.3
Kim, Y.B.4
Boss, O.5
-
32
-
-
0031038052
-
Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport
-
Bandyopadhyay G, Standaert ML, Zhao L, Yu B, Avignon A, et al. (1997) Activation of protein kinase C (alpha, beta, and zeta) by insulin in 3T3/L1 cells. Transfection studies suggest a role for PKC-zeta in glucose transport. J Biol Chem 272: 2551-2558.
-
(1997)
J Biol Chem
, vol.272
, pp. 2551-2558
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Zhao, L.3
Yu, B.4
Avignon, A.5
-
33
-
-
0141815503
-
Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both glut4 translocation and p38 MAPK activity
-
Bazuine M, Ouwens DM, Gomes de Mesquita DS, Maassen JA (2003) Arsenite stimulated glucose transport in 3T3-L1 adipocytes involves both Glut4 translocation and p38 MAPK activity. Eur J Biochem 270: 3891-3903.
-
(2003)
Eur J Biochem
, vol.270
, pp. 3891-3903
-
-
Bazuine, M.1
Ouwens, D.M.2
Gomes De Mesquita, D.S.3
Maassen, J.A.4
-
34
-
-
0035504158
-
GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: Potential activation of GLUT4 via p38 mitogen-activated protein kinase
-
Somwar R, Kim DY, Sweeney G, Huang C, Niu W, et al. (2001) GLUT4 translocation precedes the stimulation of glucose uptake by insulin in muscle cells: potential activation of GLUT4 via p38 mitogen-activated protein kinase. Biochem J 359: 639-649.
-
(2001)
Biochem J
, vol.359
, pp. 639-649
-
-
Somwar, R.1
Kim, D.Y.2
Sweeney, G.3
Huang, C.4
Niu, W.5
-
35
-
-
25144470594
-
Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes
-
Yamaguchi S, Katahira H, Ozawa S, Nakamichi Y, Tanaka T, et al. (2005) Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab 289: E643-649.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
, pp. E643-649
-
-
Yamaguchi, S.1
Katahira, H.2
Ozawa, S.3
Nakamichi, Y.4
Tanaka, T.5
-
36
-
-
4344559467
-
The glucose transporter families SGLT and GLUT: Molecular basis of normal and aberrant function
-
Scheepers A, Joost HG, Schurmann A (2004) The glucose transporter families SGLT and GLUT: molecular basis of normal and aberrant function. JPEN J Parenter Enteral Nutr 28: 364-371.
-
(2004)
JPEN J Parenter Enteral Nutr
, vol.28
, pp. 364-371
-
-
Scheepers, A.1
Joost, H.G.2
Schurmann, A.3
-
37
-
-
0033595121
-
Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus
-
Shepherd PR, Kahn BB (1999) Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus. N Engl J Med 341: 248-257.
-
(1999)
N Engl J Med
, vol.341
, pp. 248-257
-
-
Shepherd, P.R.1
Kahn, B.B.2
-
38
-
-
28544435205
-
Full intracellular retention of GLUT4 requires AS160 rab GTPase activating protein
-
Eguez L, Lee A, Chavez JA, Miinea CP, Kane S, et al. (2005) Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein. Cell Metab 2: 263-272.
-
(2005)
Cell Metab
, vol.2
, pp. 263-272
-
-
Eguez, L.1
Lee, A.2
Chavez, J.A.3
Miinea, C.P.4
Kane, S.5
-
39
-
-
27844528870
-
Characterization of the role of the rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking
-
Larance M, Ramm G, Stockli J, van Dam EM, Winata S, et al. (2005) Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem 280: 37803-37813.
-
(2005)
J Biol Chem
, vol.280
, pp. 37803-37813
-
-
Larance, M.1
Ramm, G.2
Stockli, J.3
Van Dam, E.M.4
Winata, S.5
-
40
-
-
10644289369
-
Regulation of GLUT1-mediated glucose uptake by PKClambda-PKCbeta(II) interactions in 3T3-L1 adipocytes
-
Bosch RR, Bazuine M, Span PN, Willems PH, Olthaar AJ, et al. (2004) Regulation of GLUT1-mediated glucose uptake by PKClambda-PKCbeta(II) interactions in 3T3-L1 adipocytes. Biochem J 384: 349-355.
-
(2004)
Biochem J
, vol.384
, pp. 349-355
-
-
Bosch, R.R.1
Bazuine, M.2
Span, P.N.3
Willems, P.H.4
Olthaar, A.J.5
|