-
1
-
-
33745779244
-
Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States
-
P. Nourjah, S.R. Ahmad, C. Karwoski, and M. Willy Estimates of acetaminophen (Paracetomal)-associated overdoses in the United States Pharmacoepidemiol Drug Saf 15 2006 398 405
-
(2006)
Pharmacoepidemiol Drug Saf
, vol.15
, pp. 398-405
-
-
Nourjah, P.1
Ahmad, S.R.2
Karwoski, C.3
Willy, M.4
-
2
-
-
70350482795
-
Prolonged N-acetylcysteine therapy in late acetaminophen poisoning associated with acute liver failure: A need to be more cautious?
-
T.N. Athuraliya, and A.L. Jones Prolonged N-acetylcysteine therapy in late acetaminophen poisoning associated with acute liver failure: a need to be more cautious? Crit Care 13 2009 144
-
(2009)
Crit Care
, vol.13
, pp. 144
-
-
Athuraliya, T.N.1
Jones, A.L.2
-
3
-
-
0035109768
-
Liver transplantation: Current status and novel approaches to liver replacement
-
E.B. Keeffe Liver transplantation: current status and novel approaches to liver replacement Gastroenterology 120 2001 749 762
-
(2001)
Gastroenterology
, vol.120
, pp. 749-762
-
-
Keeffe, E.B.1
-
4
-
-
11244353296
-
Alpha-fetoprotein is a predictor of outcome in acetaminophen-induced liver injury
-
L.E. Schmidt, and K. Dalhoff Alpha-fetoprotein is a predictor of outcome in acetaminophen-induced liver injury Hepatology 41 2005 26 31
-
(2005)
Hepatology
, vol.41
, pp. 26-31
-
-
Schmidt, L.E.1
Dalhoff, K.2
-
5
-
-
70349254047
-
Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury
-
U. Apte, S. Singh, G. Zeng, B. Cieply, M.A. Virji, T. Wu, and S.P. Monga Beta-catenin activation promotes liver regeneration after acetaminophen-induced injury Am J Pathol 175 2009 1056 1065
-
(2009)
Am J Pathol
, vol.175
, pp. 1056-1065
-
-
Apte, U.1
Singh, S.2
Zeng, G.3
Cieply, B.4
Virji, M.A.5
Wu, T.6
Monga, S.P.7
-
6
-
-
51149120023
-
Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in mice
-
B. Hu, and L.M. Colletti Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in mice Am J Physiol Gastrointest Liver Physiol 295 2008 G45 G53
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.295
, pp. 45-G53
-
-
Hu, B.1
Colletti, L.M.2
-
7
-
-
77953762064
-
Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity
-
B.C. Donahower, S.S. McCullough, L. Hennings, P.M. Simpson, C.D. Stowe, A.G. Saad, R.C. Kurten, J.A. Hinson, and L.P. James Human recombinant vascular endothelial growth factor reduces necrosis and enhances hepatocyte regeneration in a mouse model of acetaminophen toxicity J Pharmacol Exp Ther 334 2010 33 43
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 33-43
-
-
Donahower, B.C.1
McCullough, S.S.2
Hennings, L.3
Simpson, P.M.4
Stowe, C.D.5
Saad, A.G.6
Kurten, R.C.7
Hinson, J.A.8
James, L.P.9
-
9
-
-
13444269608
-
Tissue repair: An important determinant of final outcome of toxicant-induced injury
-
H.M. Mehendale Tissue repair: an important determinant of final outcome of toxicant-induced injury Toxicol Pathol 33 2005 41 51
-
(2005)
Toxicol Pathol
, vol.33
, pp. 41-51
-
-
Mehendale, H.M.1
-
10
-
-
0038507468
-
Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture
-
S.S. Anand, S.N. Murthy, V.S. Vaidya, M.M. Mumtaz, and H.M. Mehendale Tissue repair plays pivotal role in final outcome of liver injury following chloroform and allyl alcohol binary mixture Food Chem Toxicol 41 2003 1123 1132
-
(2003)
Food Chem Toxicol
, vol.41
, pp. 1123-1132
-
-
Anand, S.S.1
Murthy, S.N.2
Vaidya, V.S.3
Mumtaz, M.M.4
Mehendale, H.M.5
-
11
-
-
0028914370
-
Tissue repair response as a function of dose in thioacetamide hepatotoxicity
-
R.S. Mangipudy, S. Chanda, and H.M. Mehendale Tissue repair response as a function of dose in thioacetamide hepatotoxicity Environ Health Perspect 103 1995 260 267
-
(1995)
Environ Health Perspect
, vol.103
, pp. 260-267
-
-
Mangipudy, R.S.1
Chanda, S.2
Mehendale, H.M.3
-
12
-
-
0037387956
-
Mechanisms of increased liver tissue repair and survival in diet-restricted rats treated with equitoxic doses of thioacetamide
-
U.M. Apte, P.B. Limaye, D. Desaiah, T.J. Bucci, A. Warbritton, and H.M. Mehendale Mechanisms of increased liver tissue repair and survival in diet-restricted rats treated with equitoxic doses of thioacetamide Toxicol Sci 72 2003 272 282
-
(2003)
Toxicol Sci
, vol.72
, pp. 272-282
-
-
Apte, U.M.1
Limaye, P.B.2
Desaiah, D.3
Bucci, T.J.4
Warbritton, A.5
Mehendale, H.M.6
-
13
-
-
77951487860
-
Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin
-
K.N. Nejak-Bowen, M.D. Thompson, S. Singh, W.C. Bowen Jr., M.J. Dar, J. Khillan, C. Dai, and S.P. Monga Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant beta-catenin Hepatology 51 2010 1603 1613
-
(2010)
Hepatology
, vol.51
, pp. 1603-1613
-
-
Nejak-Bowen, K.N.1
Thompson, M.D.2
Singh, S.3
Bowen, W.C.4
Dar, M.J.5
Khillan, J.6
Dai, C.7
Monga, S.P.8
-
14
-
-
79959491395
-
Increased activation of the Wnt/beta-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice
-
A. Wolfe, A. Thomas, G. Edwards, R. Jaseja, G.L. Guo, and U. Apte Increased activation of the Wnt/beta-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice J Pharmacol Exp Ther 338 2011 12 21
-
(2011)
J Pharmacol Exp Ther
, vol.338
, pp. 12-21
-
-
Wolfe, A.1
Thomas, A.2
Edwards, G.3
Jaseja, R.4
Guo, G.L.5
Apte, U.6
-
15
-
-
84871876340
-
Hepatocyte-specific deletion of hepatocyte nuclear factor-4alpha in adult mice results in increased hepatocyte proliferation
-
C. Walesky, S. Gunewardena, E.F. Terwilliger, G. Edwards, P. Borude, and U. Apte Hepatocyte-specific deletion of hepatocyte nuclear factor-4alpha in adult mice results in increased hepatocyte proliferation Am J Physiol Gastrointest Liver Physiol 304 2013 G26 G37
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, pp. 26-G37
-
-
Walesky, C.1
Gunewardena, S.2
Terwilliger, E.F.3
Edwards, G.4
Borude, P.5
Apte, U.6
-
16
-
-
0034007745
-
Liver regeneration
-
N. Fausto Liver regeneration J Hepatol 32 2000 19 31
-
(2000)
J Hepatol
, vol.32
, pp. 19-31
-
-
Fausto, N.1
-
17
-
-
0037382797
-
C-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration
-
R.F. Schwabe, C.A. Bradham, T. Uehara, E. Hatano, B.L. Bennett, R. Schoonhoven, and D.A. Brenner c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration Hepatology 37 2003 824 832
-
(2003)
Hepatology
, vol.37
, pp. 824-832
-
-
Schwabe, R.F.1
Bradham, C.A.2
Uehara, T.3
Hatano, E.4
Bennett, B.L.5
Schoonhoven, R.6
Brenner, D.A.7
-
18
-
-
84855892790
-
Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity
-
H. Jaeschke, M.R. McGill, and A. Ramachandran Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity Drug Metab Rev 44 2012 88 106
-
(2012)
Drug Metab Rev
, vol.44
, pp. 88-106
-
-
Jaeschke, H.1
McGill, M.R.2
Ramachandran, A.3
-
19
-
-
47949101861
-
Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury
-
M. Bourdi, M.C. Korrapati, M. Chakraborty, S.B. Yee, and L.R. Pohl Protective role of c-Jun N-terminal kinase 2 in acetaminophen-induced liver injury Biochem Biophys Res Commun 374 2008 6 10
-
(2008)
Biochem Biophys Res Commun
, vol.374
, pp. 6-10
-
-
Bourdi, M.1
Korrapati, M.C.2
Chakraborty, M.3
Yee, S.B.4
Pohl, L.R.5
-
20
-
-
0032588186
-
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1
-
D.C. Guttridge, C. Albanese, J.Y. Reuther, R.G. Pestell, and A.S. Baldwin Jr. NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1 Mol Cell Biol 19 1999 5785 5799
-
(1999)
Mol Cell Biol
, vol.19
, pp. 5785-5799
-
-
Guttridge, D.C.1
Albanese, C.2
Reuther, J.Y.3
Pestell, R.G.4
Baldwin, A.S.5
-
21
-
-
11844269840
-
Phosphorylation of NF-kappaB and IkappaB proteins: Implications in cancer and inflammation
-
P. Viatour, M.P. Merville, V. Bours, and A. Chariot Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation Trends Biochem Sci 30 2005 43 52
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 43-52
-
-
Viatour, P.1
Merville, M.P.2
Bours, V.3
Chariot, A.4
-
22
-
-
79952043062
-
Beta-catenin signaling, liver regeneration and hepatocellular cancer: Sorting the good from the bad
-
K.N. Nejak-Bowen, and S.P. Monga Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad Semin Cancer Biol 21 2011 44 58
-
(2011)
Semin Cancer Biol
, vol.21
, pp. 44-58
-
-
Nejak-Bowen, K.N.1
Monga, S.P.2
-
23
-
-
33846450620
-
Wnt'er in liver: Expression of Wnt and frizzled genes in mouse
-
G. Zeng, F. Awan, W. Otruba, P. Muller, U. Apte, X. Tan, C. Gandhi, A.J. Demetris, and S.P. Monga Wnt'er in liver: expression of Wnt and frizzled genes in mouse Hepatology 45 2007 195 204
-
(2007)
Hepatology
, vol.45
, pp. 195-204
-
-
Zeng, G.1
Awan, F.2
Otruba, W.3
Muller, P.4
Apte, U.5
Tan, X.6
Gandhi, C.7
Demetris, A.J.8
Monga, S.P.9
-
24
-
-
79958827787
-
The transforming growth factor-alpha and cyclin D1 genes are direct targets of beta-catenin signaling in hepatocyte proliferation
-
C. Torre, S. Benhamouche, C. Mitchell, C. Godard, P. Veber, F. Letourneur, N. Cagnard, S. Jacques, L. Finzi, C. Perret, and S. Colnot The transforming growth factor-alpha and cyclin D1 genes are direct targets of beta-catenin signaling in hepatocyte proliferation J Hepatol 55 2011 86 95
-
(2011)
J Hepatol
, vol.55
, pp. 86-95
-
-
Torre, C.1
Benhamouche, S.2
Mitchell, C.3
Godard, C.4
Veber, P.5
Letourneur, F.6
Cagnard, N.7
Jacques, S.8
Finzi, L.9
Perret, C.10
Colnot, S.11
-
25
-
-
42249102412
-
Acute liver failure: Summary of a workshop
-
W.M. Lee, R.H. Squires Jr., S.L. Nyberg, E. Doo, and J.H. Hoofnagle Acute liver failure: summary of a workshop Hepatology 47 2008 1401 1415
-
(2008)
Hepatology
, vol.47
, pp. 1401-1415
-
-
Lee, W.M.1
Squires, R.H.2
Nyberg, S.L.3
Doo, E.4
Hoofnagle, J.H.5
-
26
-
-
0037236634
-
Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform
-
S.S. Anand, M.G. Soni, V.S. Vaidya, S.N. Murthy, M.M. Mumtaz, and H.M. Mehendale Extent and timeliness of tissue repair determines the dose-related hepatotoxicity of chloroform Int J Toxicol 22 2003 25 33
-
(2003)
Int J Toxicol
, vol.22
, pp. 25-33
-
-
Anand, S.S.1
Soni, M.G.2
Vaidya, V.S.3
Murthy, S.N.4
Mumtaz, M.M.5
Mehendale, H.M.6
-
27
-
-
0031588966
-
Tissue injury and repair as parallel and opposing responses to CCl4 hepatotoxicity: A novel dose-response
-
P.S. Rao, R.S. Mangipudy, and H.M. Mehendale Tissue injury and repair as parallel and opposing responses to CCl4 hepatotoxicity: a novel dose-response Toxicology 118 1997 181 193
-
(1997)
Toxicology
, vol.118
, pp. 181-193
-
-
Rao, P.S.1
Mangipudy, R.S.2
Mehendale, H.M.3
-
28
-
-
0036862006
-
Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy
-
A. Koteish, S. Yang, H. Lin, J. Huang, and A.M. Diehl Ethanol induces redox-sensitive cell-cycle inhibitors and inhibits liver regeneration after partial hepatectomy Alcohol Clin Exp Res 26 2002 1710 1718
-
(2002)
Alcohol Clin Exp Res
, vol.26
, pp. 1710-1718
-
-
Koteish, A.1
Yang, S.2
Lin, H.3
Huang, J.4
Diehl, A.M.5
-
29
-
-
84883210289
-
The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice
-
L.E. Buitrago-Molina, S. Marhenke, T. Longerich, A.D. Sharma, A.E. Boukouris, R. Geffers, B. Guigas, M.P. Manns, and A. Vogel The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice Hepatology 58 2013 1143 1152
-
(2013)
Hepatology
, vol.58
, pp. 1143-1152
-
-
Buitrago-Molina, L.E.1
Marhenke, S.2
Longerich, T.3
Sharma, A.D.4
Boukouris, A.E.5
Geffers, R.6
Guigas, B.7
Manns, M.P.8
Vogel, A.9
-
31
-
-
0027416617
-
Administration of hepatic stimulatory substance alone or with other liver growth factors does not ameliorate acetaminophen-induced liver failure
-
A. Francavilla, A. Azzarone, G. Carrieri, U. Cillo, D. Van Thiel, V. Subbottin, and T.E. Starzl Administration of hepatic stimulatory substance alone or with other liver growth factors does not ameliorate acetaminophen-induced liver failure Hepatology 17 1993 429 433
-
(1993)
Hepatology
, vol.17
, pp. 429-433
-
-
Francavilla, A.1
Azzarone, A.2
Carrieri, G.3
Cillo, U.4
Van Thiel, D.5
Subbottin, V.6
Starzl, T.E.7
-
32
-
-
0027976450
-
Plasma hepatocyte growth factor and biliprotein levels and outcome in fulminant hepatic failure
-
R.D. Hughes, L. Zhang, H. Tsubouchi, Y. Daikuhara, and R. Williams Plasma hepatocyte growth factor and biliprotein levels and outcome in fulminant hepatic failure J Hepatol 20 1994 106 111
-
(1994)
J Hepatol
, vol.20
, pp. 106-111
-
-
Hughes, R.D.1
Zhang, L.2
Tsubouchi, H.3
Daikuhara, Y.4
Williams, R.5
-
33
-
-
1242336976
-
Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice
-
M. Horimoto, P. Fulop, Z. Derdak, J.R. Wands, and G. Baffy Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice Hepatology 39 2004 386 392
-
(2004)
Hepatology
, vol.39
, pp. 386-392
-
-
Horimoto, M.1
Fulop, P.2
Derdak, Z.3
Wands, J.R.4
Baffy, G.5
-
34
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway J Biol Chem 271 1996 20608 20616
-
(1996)
J Biol Chem
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
35
-
-
0036314662
-
STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers
-
M. Torbenson, S.Q. Yang, H.Z. Liu, J. Huang, W. Gage, and A.M. Diehl STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers Am J Pathol 161 2002 155 161
-
(2002)
Am J Pathol
, vol.161
, pp. 155-161
-
-
Torbenson, M.1
Yang, S.Q.2
Liu, H.Z.3
Huang, J.4
Gage, W.5
Diehl, A.M.6
-
36
-
-
0033839769
-
Hyperstimulation with interleukin 6 inhibits cell cycle progression after hepatectomy in mice
-
T. Wustefeld, T. Rakemann, S. Kubicka, M.P. Manns, and C. Trautwein Hyperstimulation with interleukin 6 inhibits cell cycle progression after hepatectomy in mice Hepatology 32 2000 514 522
-
(2000)
Hepatology
, vol.32
, pp. 514-522
-
-
Wustefeld, T.1
Rakemann, T.2
Kubicka, S.3
Manns, M.P.4
Trautwein, C.5
-
37
-
-
0345687490
-
Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice
-
H. Chiu, C.R. Gardner, D.M. Dambach, S.K. Durham, J.A. Brittingham, J.D. Laskin, and D.L. Laskin Role of tumor necrosis factor receptor 1 (p55) in hepatocyte proliferation during acetaminophen-induced toxicity in mice Toxicol Appl Pharmacol 193 2003 218 227
-
(2003)
Toxicol Appl Pharmacol
, vol.193
, pp. 218-227
-
-
Chiu, H.1
Gardner, C.R.2
Dambach, D.M.3
Durham, S.K.4
Brittingham, J.A.5
Laskin, J.D.6
Laskin, D.L.7
-
38
-
-
21244451115
-
Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: A kinetic study of proliferating cell nuclear antigen and cytokine expression
-
L.P. James, R.C. Kurten, L.W. Lamps, S. McCullough, and J.A. Hinson Tumour necrosis factor receptor 1 and hepatocyte regeneration in acetaminophen toxicity: a kinetic study of proliferating cell nuclear antigen and cytokine expression Basic Clin Pharmacol Toxicol 97 2005 8 14
-
(2005)
Basic Clin Pharmacol Toxicol
, vol.97
, pp. 8-14
-
-
James, L.P.1
Kurten, R.C.2
Lamps, L.W.3
McCullough, S.4
Hinson, J.A.5
-
39
-
-
81055149723
-
Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity
-
R. Yang, S. Zhang, H. Kajander, S. Zhu, M.L. Koskinen, and J. Tenhunen Ringer's lactate improves liver recovery in a murine model of acetaminophen toxicity BMC Gastroenterol 11 2011 125
-
(2011)
BMC Gastroenterol
, vol.11
, pp. 125
-
-
Yang, R.1
Zhang, S.2
Kajander, H.3
Zhu, S.4
Koskinen, M.L.5
Tenhunen, J.6
-
40
-
-
65449172838
-
Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity
-
R. Yang, K. Miki, X. He, M.E. Killeen, and M.P. Fink Prolonged treatment with N-acetylcystine delays liver recovery from acetaminophen hepatotoxicity Crit Care 13 2009 9
-
(2009)
Crit Care
, vol.13
, pp. 9
-
-
Yang, R.1
Miki, K.2
He, X.3
Killeen, M.E.4
Fink, M.P.5
|