War and peace at the feto-placental front line: Recurrent spontaneous abortion

Israel Medical Association Journal

Volumn 16, Issue 10, 2014, Pages 667-668

  De Carolis, Caterina ^a   Perricone, Carlo ^b   Perricone, Roberto ^c  

^a SAN GIOVANNI ADDOLORATA HOSPITAL   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Cytokines; Natural killer cells (NK); Recurrent spontaneous abortion (RSA) antiphospholipid syndrome (APS); Thyroid

Indexed keywords

CYTOKINE; PHOSPHOLIPID ANTIBODY;

ABORTION, HABITUAL; BLOOD; FEMALE; FETOMATERNAL TRANSFUSION; HUMAN; IMMUNOLOGY; LYMPHOCYTE COUNT; NATURAL KILLER CELL; PHYSIOLOGY; PLACENTA CIRCULATION; PREGNANCY; PROCEDURES; TH1 CELL; THYROID GLAND;

ABORTION, HABITUAL; ANTIBODIES, ANTIPHOSPHOLIPID; CYTOKINES; FEMALE; HUMANS; KILLER CELLS, NATURAL; LYMPHOCYTE COUNT; MATERNAL-FETAL EXCHANGE; PLACENTAL CIRCULATION; PREGNANCY; TH1 CELLS; THYROID GLAND;

EID: 84908174000     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (10)

1. Wilczynski JR (2005) Th1/Th2 cytokines balance – yin and yang of reproductive immunology [Review]. Eur J Obstet Gynecol Reprod Biol 2005; 122: 136-43
2. Practice Committee of the American Society for Reproductive Medicine. Evaluation and treatment of recurrent pregnancy loss: a committee opinion. Fertil Steril 2012; 98: 1103-11
3. Perricone C, De Carolis C, Giacomelli R, et al. High levels of NK cells in the peripheral blood of patients affected with anti-phospholipid syndrome and recurrent spontaneous abortion: a potential new hypothesis. Rheumatology (Oxford) 2007; 46: 1574-8
4. Aoki K, Kajiura S, Matsumoto Y, et al. 1995. Preconceptional natural-killercell activity as a predictor of miscarriage. Lancet 1995; 345: 1340-2
5. Carp HJ, Shoenfeld Y. Recurrent spontaneous abortions in antiphospholipid syndrome: natural killer cells – an additional mechanism in a multi factorial process. Rheumatology (Oxford) 2007; 46: 1517-19
6. Perricone R, Di Muzio G, Perricone C, et al. High levels of peripheral blood NK cells in women suffering from recurrent spontaneous abortion are reverted from high-dose intravenous immunoglobulins. Am J Reprod Immunol 2006; 55: 232-9
7. Galarza-Maldonado C, Kourilovitch MR, Perez-Fernandez OM, et al. Obstetric antiphospholipid syndrome [Review]. Autoimmun Rev 2012; 11 (4): 288-95
8. Carvalheiras G, Faria R, Braga J, Vasconcelos C. Fetal outcome in autoimmune diseases [Review]. Autoimmun Rev 2012; 11 (6-7): A520-30
9. De Carolis C, Greco E, Guarino MD, et al. Anti-thyroid antibodies and antiphospholipid syndrome: evidence of reduced fecundity and poor pregnancy outcome in recurrent spontaneous aborters. Am J Reprod Immunol 2004; 52: 263-6
10. Twig G, Shina A, Amital H, Shoenfeld Y. Pathogenesis of infertility and recurrent pregnancy loss in thyroid autoimmunity. J Autoimm 2012; 38: 275-81