Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway

Cancer Letters

Volumn 355, Issue 2, 2014, Pages 273-280

  Zhang, Wanying ^a   Li, Haonan ^a   Yang, Yihe ^a   Liao, Jie ^a   Yang, Guang Yu ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

AKR1B10; E cadherin; Invasion; KRAS; Migration; Pancreatic adenocarcinoma

Indexed keywords

ALDO KETO REDUCTASE 1B10; K RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; OLEANOLIC ACID; OXIDOREDUCTASE; RAF PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; UVOMORULIN; AKR1B10 PROTEIN, HUMAN; ALDEHYDE REDUCTASE; CADHERIN; CD18 ANTIGEN; ENZYME INHIBITOR; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN; SMALL INTERFERING RNA;

ANCHORAGE INDEPENDENT GROWTH; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CD18 CELL LINE; CELL INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; GENE SILENCING; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IC50; IMMUNOHISTOCHEMISTRY; MIGRATION INHIBITION; MOUSE; NONHUMAN; ONCOLOGICAL PARAMETERS; PANCREAS CARCINOMA; PANCREATIC CANCER CELL LINE; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TUMOR WEIGHT; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUDE MOUSE; ONCOGENE RAS; PANCREATIC NEOPLASMS; PATHOLOGY; TUMOR CELL LINE; UPREGULATION;

ALDEHYDE REDUCTASE; ANIMALS; ANTIGENS, CD18; CADHERINS; CELL LINE, TUMOR; DOWN-REGULATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENES, RAS; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; OLEANOLIC ACID; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84908170196     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.09.031     Document Type: Article

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