메뉴 건너뛰기




Volumn 12, Issue 1, 2014, Pages

The prognostic value of microRNA-126 and microvessel density in patients with stage II colon cancer: Results from a population cohort

Author keywords

Angiogenesis; Colon cancer; Duke's B; microRNA 126; Microvessel density; Prognostic markers

Indexed keywords

ENDOGLIN; MICRORNA 126; MICRORNA; MIRN126 MICRORNA, HUMAN;

EID: 84908137028     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-014-0254-6     Document Type: Article
Times cited : (19)

References (44)
  • 2
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
    • 8996149
    • O'Connell MJ, Mailliard JA, Kahn MJ, Macdonald JS, Haller DG, Mayer RJ, Wieand HS. Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol 1997, 15:246-250. 8996149.
    • (1997) J Clin Oncol , vol.15 , pp. 246-250
    • O'Connell, M.J.1    Mailliard, J.A.2    Kahn, M.J.3    Macdonald, J.S.4    Haller, D.G.5    Mayer, R.J.6    Wieand, H.S.7
  • 6
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • 21376230
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674. 10.1016/j.cell.2011.02.013, 21376230.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • 1688381
    • Folkman J. What is the evidence that tumors are angiogenesis dependent?. J Natl Cancer Inst 1990, 82:4-6. 10.1093/jnci/82.1.4, 1688381.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 8
    • 33745102388 scopus 로고    scopus 로고
    • Microvessel density and VEGF expression are prognostic factors in colorectal cancer. Meta-analysis of the literature
    • Des GG, Uzzan B, Nicolas P, Cucherat M, Morere JF, Benamouzig R, Breau JL, Perret GY. Microvessel density and VEGF expression are prognostic factors in colorectal cancer. Meta-analysis of the literature. Br J Cancer 2006, 94:1823-1832. 10.1038/sj.bjc.6603176.
    • (2006) Br J Cancer , vol.94 , pp. 1823-1832
    • Des, G.G.1    Uzzan, B.2    Nicolas, P.3    Cucherat, M.4    Morere, J.F.5    Benamouzig, R.6    Breau, J.L.7    Perret, G.Y.8
  • 9
    • 0026083903 scopus 로고
    • Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma
    • 1701519
    • Weidner N, Semple JP, Welch WR, Folkman J. Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma. N Engl J Med 1991, 324:1-8. 10.1056/NEJM199101033240101, 1701519.
    • (1991) N Engl J Med , vol.324 , pp. 1-8
    • Weidner, N.1    Semple, J.P.2    Welch, W.R.3    Folkman, J.4
  • 10
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
    • 18197166
    • Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?. Nat Rev Genet 2008, 9:102-114. 10.1038/nrg2290, 18197166.
    • (2008) Nat Rev Genet , vol.9 , pp. 102-114
    • Filipowicz, W.1    Bhattacharyya, S.N.2    Sonenberg, N.3
  • 11
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • 16557279
    • Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006, 6:259-269. 10.1038/nrc1840, 16557279.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 12
    • 75349097162 scopus 로고    scopus 로고
    • MicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard
    • 19782719
    • Heusschen R, van Gink M, Griffioen AW, Thijssen VL. MicroRNAs in the tumor endothelium: novel controls on the angioregulatory switchboard. Biochim Biophys Acta 2010, 1805:87-96. 19782719.
    • (2010) Biochim Biophys Acta , vol.1805 , pp. 87-96
    • Heusschen, R.1    van Gink, M.2    Griffioen, A.W.3    Thijssen, V.L.4
  • 15
    • 79953702227 scopus 로고    scopus 로고
    • Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2
    • 21249429
    • Zhu N, Zhang D, Xie H, Zhou Z, Chen H, Hu T, Bai Y, Shen Y, Yuan W, Jing Q, Qin Y. Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2. Mol Cell Biochem 2011, 351:157-164. 10.1007/s11010-011-0723-7, 21249429.
    • (2011) Mol Cell Biochem , vol.351 , pp. 157-164
    • Zhu, N.1    Zhang, D.2    Xie, H.3    Zhou, Z.4    Chen, H.5    Hu, T.6    Bai, Y.7    Shen, Y.8    Yuan, W.9    Jing, Q.10    Qin, Y.11
  • 16
    • 79959954361 scopus 로고    scopus 로고
    • Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: coexpression with vascular endothelial growth factor-A predicts poor survival
    • 21264844
    • Donnem T, Lonvik K, Eklo K, Berg T, Sorbye SW, Al-Shibli K, Al-Saad S, Andersen S, Stenvold H, Bremnes RM, Busund LT. Independent and tissue-specific prognostic impact of miR-126 in nonsmall cell lung cancer: coexpression with vascular endothelial growth factor-A predicts poor survival. Cancer 2011, 117:3193-3200. 10.1002/cncr.25907, 21264844.
    • (2011) Cancer , vol.117 , pp. 3193-3200
    • Donnem, T.1    Lonvik, K.2    Eklo, K.3    Berg, T.4    Sorbye, S.W.5    Al-Shibli, K.6    Al-Saad, S.7    Andersen, S.8    Stenvold, H.9    Bremnes, R.M.10    Busund, L.T.11
  • 18
    • 84855813448 scopus 로고    scopus 로고
    • A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
    • 22170610
    • Png KJ, Halberg N, Yoshida M, Tavazoie SF. A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 2011, 481:190-194. 10.1038/nature10661, 22170610.
    • (2011) Nature , vol.481 , pp. 190-194
    • Png, K.J.1    Halberg, N.2    Yoshida, M.3    Tavazoie, S.F.4
  • 19
    • 84864881089 scopus 로고    scopus 로고
    • Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer
    • 22836510
    • Sasahira T, Kurihara M, Bhawal UK, Ueda N, Shimomoto T, Yamamoto K, Kirita T, Kuniyasu H. Downregulation of miR-126 induces angiogenesis and lymphangiogenesis by activation of VEGF-A in oral cancer. Br J Cancer 2012, 107:700-706. 10.1038/bjc.2012.330, 22836510.
    • (2012) Br J Cancer , vol.107 , pp. 700-706
    • Sasahira, T.1    Kurihara, M.2    Bhawal, U.K.3    Ueda, N.4    Shimomoto, T.5    Yamamoto, K.6    Kirita, T.7    Kuniyasu, H.8
  • 20
    • 84866653610 scopus 로고    scopus 로고
    • let-7b and miR-126 are down-regulated in tumor tissue and correlate with microvessel density and survival outcomes in non--small--cell lung cancer
    • Jusufovic E, Rijavec M, Keser D, Korosec P, Sodja E, Iljazovic E, Radojevic Z, Kosnik M: let-7b and miR-126 are down-regulated in tumor tissue and correlate with microvessel density and survival outcomes in non--small--cell lung cancer.PLoS One 2012, doi:10.1371/journal.pone.0045577.
    • (2012) PLoS One
    • Jusufovic, E.1    Rijavec, M.2    Keser, D.3    Korosec, P.4    Sodja, E.5    Iljazovic, E.6    Radojevic, Z.7    Kosnik, M.8
  • 23
    • 84857942226 scopus 로고    scopus 로고
    • The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer
    • Hansen TF, Soerensen FB, Lindebjerg J, Jakobsen A: The predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancer.BMC Cancer 2012, doi:10.1186/1471-2407-12-83.
    • (2012) BMC Cancer
    • Hansen, T.F.1    Soerensen, F.B.2    Lindebjerg, J.3    Jakobsen, A.4
  • 24
    • 24944452378 scopus 로고    scopus 로고
    • REporting recommendations for tumour MARKer prognostic studies (REMARK)
    • 16106245
    • McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, Clark GM. REporting recommendations for tumour MARKer prognostic studies (REMARK). Br J Cancer 2005, 93:387-391. 10.1038/sj.bjc.6602678, 16106245.
    • (2005) Br J Cancer , vol.93 , pp. 387-391
    • McShane, L.M.1    Altman, D.G.2    Sauerbrei, W.3    Taube, S.E.4    Gion, M.5    Clark, G.M.6
  • 27
    • 77949724737 scopus 로고    scopus 로고
    • Microvessel density and the association with single nucleotide polymorphisms of the vascular endothelial growth factor receptor 2 in patients with colorectal cancer
    • 20143086
    • Hansen TF, Sorensen FB, Spindler KL, Olsen DA, Andersen RF, Lindebjerg J, Brandslund I, Jakobsen A. Microvessel density and the association with single nucleotide polymorphisms of the vascular endothelial growth factor receptor 2 in patients with colorectal cancer. Virchows Arch 2010, 456:251-260. 10.1007/s00428-009-0878-8, 20143086.
    • (2010) Virchows Arch , vol.456 , pp. 251-260
    • Hansen, T.F.1    Sorensen, F.B.2    Spindler, K.L.3    Olsen, D.A.4    Andersen, R.F.5    Lindebjerg, J.6    Brandslund, I.7    Jakobsen, A.8
  • 28
    • 0018087404 scopus 로고
    • Estimators of the number of objects per area unbiased by edge effects
    • Gundersen HJ. Estimators of the number of objects per area unbiased by edge effects. Microsc Acta 1978, 81:07-117.
    • (1978) Microsc Acta , vol.81 , pp. 7-117
    • Gundersen, H.J.1
  • 29
    • 79957894276 scopus 로고    scopus 로고
    • Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
    • 21629292
    • Carmeliet P, Jain RK. Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases. Nat Rev Drug Discov 2011, 10:417-427. 10.1038/nrd3455, 21629292.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 417-427
    • Carmeliet, P.1    Jain, R.K.2
  • 30
    • 84655175072 scopus 로고    scopus 로고
    • Down-regulation of miR-126 expression in colorectal cancer and its clinical significance
    • 20680522
    • Li XM, Wang AM, Zhang J, Yi H. Down-regulation of miR-126 expression in colorectal cancer and its clinical significance. Med Oncol 2011, 28:1054-1057. 10.1007/s12032-010-9637-6, 20680522.
    • (2011) Med Oncol , vol.28 , pp. 1054-1057
    • Li, X.M.1    Wang, A.M.2    Zhang, J.3    Yi, H.4
  • 31
    • 80052713735 scopus 로고    scopus 로고
    • Elevated microRNA-126 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in colorectal cancer
    • 22848274
    • Hansen TF, Andersen CL, Nielsen BS, Spindler KL, Sorensen FB, Lindebjerg J, Brandslund I, Jakobsen A. Elevated microRNA-126 is associated with high vascular endothelial growth factor receptor 2 expression levels and high microvessel density in colorectal cancer. Oncol Lett 2011, 2:1101-1106. 22848274.
    • (2011) Oncol Lett , vol.2 , pp. 1101-1106
    • Hansen, T.F.1    Andersen, C.L.2    Nielsen, B.S.3    Spindler, K.L.4    Sorensen, F.B.5    Lindebjerg, J.6    Brandslund, I.7    Jakobsen, A.8
  • 32
    • 52249096359 scopus 로고    scopus 로고
    • The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers
    • 18663744
    • Guo C, Sah JF, Beard L, Willson JK, Markowitz SD, Guda K. The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers. Genes Chromosomes Cancer 2008, 47:939-946. 10.1002/gcc.20596, 18663744.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 939-946
    • Guo, C.1    Sah, J.F.2    Beard, L.3    Willson, J.K.4    Markowitz, S.D.5    Guda, K.6
  • 33
    • 84881659562 scopus 로고    scopus 로고
    • Visualising and quantifying angiogenesis in metastatic colorectal cancer: A comparison of methods and their predictive value for chemotherapy response
    • Hansen TF, Nielsen BS, Jakobsen A, Sorensen FB. Visualising and quantifying angiogenesis in metastatic colorectal cancer: A comparison of methods and their predictive value for chemotherapy response. Cell Oncol 2013, 36:341-350. 10.1007/s13402-013-0139-3.
    • (2013) Cell Oncol , vol.36 , pp. 341-350
    • Hansen, T.F.1    Nielsen, B.S.2    Jakobsen, A.3    Sorensen, F.B.4
  • 34
    • 84893461051 scopus 로고    scopus 로고
    • MiR-126 in human cancers: Clinical roles and current perspectives
    • 24368110
    • Ebrahimi F, Gopalan V, Smith RA, Lam AK-Y. miR-126 in human cancers: Clinical roles and current perspectives. Exp Mol Pathol 2014, 96:98-107. 10.1016/j.yexmp.2013.12.004, 24368110.
    • (2014) Exp Mol Pathol , vol.96 , pp. 98-107
    • Ebrahimi, F.1    Gopalan, V.2    Smith, R.A.3    Lam, A.K.-Y.4
  • 37
    • 77951587943 scopus 로고    scopus 로고
    • MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer
    • 20429937
    • Chang KH, Mestdagh P, Vandesompele J, Kerin MJ, Miller N. MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer 2010, 10:173. 10.1186/1471-2407-10-173, 20429937.
    • (2010) BMC Cancer , vol.10 , pp. 173
    • Chang, K.H.1    Mestdagh, P.2    Vandesompele, J.3    Kerin, M.J.4    Miller, N.5
  • 38
    • 78149407836 scopus 로고    scopus 로고
    • Normalization strategies for microRNA profiling experiments: a " normal" way to a hidden layer of complexity?
    • 20703800
    • Meyer SU, Pfaffl MW, Ulbrich SE. Normalization strategies for microRNA profiling experiments: a " normal" way to a hidden layer of complexity?. Biotechnol Lett 2010, 32:1777-1788. 10.1007/s10529-010-0380-z, 20703800.
    • (2010) Biotechnol Lett , vol.32 , pp. 1777-1788
    • Meyer, S.U.1    Pfaffl, M.W.2    Ulbrich, S.E.3
  • 40
    • 0037134709 scopus 로고    scopus 로고
    • Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us
    • 12072542
    • Hlatky L, Hahnfeldt P, Folkman J. Clinical application of antiangiogenic therapy: microvessel density, what it does and doesn't tell us. J Natl Cancer Inst 2002, 94:883-893. 10.1093/jnci/94.12.883, 12072542.
    • (2002) J Natl Cancer Inst , vol.94 , pp. 883-893
    • Hlatky, L.1    Hahnfeldt, P.2    Folkman, J.3
  • 41
    • 0035017536 scopus 로고    scopus 로고
    • Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies
    • 11382917
    • Fonsatti E, Del VL, Altomonte M, Sigalotti L, Nicotra MR, Coral S, Natali PG, Maio M. Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies. J Cell Physiol 2001, 188:1-7. 10.1002/jcp.1095, 11382917.
    • (2001) J Cell Physiol , vol.188 , pp. 1-7
    • Fonsatti, E.1    Del, V.L.2    Altomonte, M.3    Sigalotti, L.4    Nicotra, M.R.5    Coral, S.6    Natali, P.G.7    Maio, M.8
  • 42
    • 33644823334 scopus 로고    scopus 로고
    • Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer
    • 16365183
    • Jubb AM, Hurwitz HI, Bai W, Holmgren EB, Tobin P, Guerrero AS, Kabbinavar F, Holden SN, Novotny WF, Frantz GD, Hillan KJ, Koeppen H. Impact of vascular endothelial growth factor-A expression, thrombospondin-2 expression, and microvessel density on the treatment effect of bevacizumab in metastatic colorectal cancer. J Clin Oncol 2006, 24:217-227. 10.1200/JCO.2005.01.5388, 16365183.
    • (2006) J Clin Oncol , vol.24 , pp. 217-227
    • Jubb, A.M.1    Hurwitz, H.I.2    Bai, W.3    Holmgren, E.B.4    Tobin, P.5    Guerrero, A.S.6    Kabbinavar, F.7    Holden, S.N.8    Novotny, W.F.9    Frantz, G.D.10    Hillan, K.J.11    Koeppen, H.12
  • 43
    • 84862676572 scopus 로고    scopus 로고
    • The relationship between the stromal mast cell number, microvessel density, c-erbB-2 staining and survival and prognostic factors in colorectal carcinoma
    • 22627628
    • Elezoglu B, Tolunay S. The relationship between the stromal mast cell number, microvessel density, c-erbB-2 staining and survival and prognostic factors in colorectal carcinoma. Turk Patoloji Derg 2012, 28:110-118. 22627628.
    • (2012) Turk Patoloji Derg , vol.28 , pp. 110-118
    • Elezoglu, B.1    Tolunay, S.2
  • 44
    • 58149260293 scopus 로고    scopus 로고
    • Clinical and biological significance of angiogenesis and lymphangiogenesis in colorectal cancer
    • 19038587
    • Gao J, Knutsen A, Arbman G, Carstensen J, Franlund B, Sun XF. Clinical and biological significance of angiogenesis and lymphangiogenesis in colorectal cancer. Dig Liver Dis 2009, 41:116-122. 10.1016/j.dld.2008.07.315, 19038587.
    • (2009) Dig Liver Dis , vol.41 , pp. 116-122
    • Gao, J.1    Knutsen, A.2    Arbman, G.3    Carstensen, J.4    Franlund, B.5    Sun, X.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.