Urinary metabolomics revealed arsenic internal dose-related metabolic alterations: A proof-of-concept study in a chinese male cohort

Environmental Science and Technology

Volumn 48, Issue 20, 2014, Pages 12265-12274

  Zhang, Jie ^a   Shen, Heqing ^a   Xu, Weipan ^a   Xia, Yankai ^b   Barr, Dana Boyd ^c   Mu, Xiaoli ^a   Wang, Xiaoxue ^a   Liu, Liangpo ^a   Huang, Qingyu ^a   Tian, Meiping ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOMARKERS; HEALTH RISKS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEAST SQUARES APPROXIMATIONS; MASS SPECTROMETRY; METABOLISM; POSITIVE IONS; RISK ASSESSMENT;

ALCOHOL CONSUMPTION; BIOCHEMICAL CHANGES; DIMETHYLARSINIC ACIDS; ENDOCRINE DISRUPTION; METABOLIC BIOMARKERS; METHYLARSONIC ACIDS; PARTIAL LEAST SQUARES DISCRIMINANTS; QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY;

ARSENIC;

ARSENIC; ARSENOBETAINE; BIOLOGICAL MARKER; CACODYLIC ACID; GUANINE; HIPPURIC ACID; METHANEARSONIC ACID; TESTOSTERONE; HIPPURIC ACID DERIVATIVE; ORGANOARSENIC DERIVATIVE;

ARSENIC; ASSESSMENT METHOD; BIOCHEMICAL COMPOSITION; BIOMONITORING; COHORT ANALYSIS; DOSE-RESPONSE RELATIONSHIP; ENDOCRINE DISRUPTOR; MASS SPECTROMETRY; METABOLISM; NUMERICAL MODEL; ORGANIC ACID; POLLUTION EXPOSURE; RISK ASSESSMENT;

ADULT; ALCOHOL CONSUMPTION; AREA UNDER THE CURVE; ARTICLE; BODY MASS; CHINESE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MASS SPECTROMETRY; METABOLIC DISORDER; METABOLIC REGULATION; METABOLOME; METABOLOMICS; OXIDATIVE STRESS; QUESTIONNAIRE; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SMOKING; TIME OF FLIGHT MASS SPECTROMETRY; URINALYSIS; URINARY METABOLOMICS; URINE; ENVIRONMENTAL MONITORING; REGRESSION ANALYSIS; YOUNG ADULT;

ADULT; ARSENIC; ARSENICALS; BIOMARKERS; CACODYLIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENVIRONMENTAL MONITORING; GUANINE; HIPPURATES; HUMANS; LEAST-SQUARES ANALYSIS; MALE; MASS SPECTROMETRY; METABOLOME; METABOLOMICS; TESTOSTERONE; YOUNG ADULT;

EID: 84908136039     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es503659w     Document Type: Article

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