Serum metabolomic pertubations among workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Environmental and Molecular Mutagenesis

Volumn 54, Issue 7, 2013, Pages 558-565

  Saberi Hosnijeh, Fatemeh ^a,b   Pechlivanis, Alexandros ^c   Keun, Hector C ^c   Portengen, Lützen ^a   Bueno de Mesquita, H Bas ^d,e   Heederik, Dick ^a   Vermeulen, Roel ^a,e  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ZANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Cross sectional study; Dioxin; Metabolomics; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN;

ADULT; AGED; ARTICLE; BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; MASS FRAGMENTOGRAPHY; METABOLOMICS; OCCUPATIONAL EXPOSURE; QUALITY CONTROL; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

CROSS SECTIONAL STUDY; DIOXIN; METABOLOMICS; TCDD;

AGED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COHORT STUDIES; HUMANS; MASS SPECTROMETRY; METABOLOMICS; MIDDLE AGED; OCCUPATIONAL EXPOSURE; TETRACHLORODIBENZODIOXIN;

EID: 84882237628     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21802     Document Type: Article

References (20)

1. Aylward LL, Brunet RC, Starr TB, Carrier G, Delzell E, Cheng H, Beall C. 2005. Exposure reconstruction for the TCDD-exposed NIOSH cohort using a concentration- and age-dependent model of elimination. Risk Anal 25:945-956.
2. Boers D, Portengen L, Bueno-de-Mesquita HB, Heederik DJJ, Vermeulen R. 2010. Cause-specific mortality of Dutch chlorophenoxy herbicide manufacturing workers. Occup Environ Med 67:24-31.
3. Boers D, Portengen L, Turner WE, Bueno-de-Mesquita HB, Heederik D, Vermeulen R. 2012. Plasma dioxin levels and cause-specific mortality in an occupational cohort of workers exposed to chlorophenoxy herbicides, chlorophenols and contaminants. Occup Environ Med 69:113-118.
4. Boffetta P, Mundt KA, Adami HO, Cole P, Mandel JS. 2011. TCDD and cancer: A critical review of epidemiologic studies. Crit Rev Toxicol 41:622-636.
5. Bueno de Mesquita HB, Doornbos G, van der Kuip DA, Kogevinas M, Winkelmann R. 1993. Occupational exposure to phenoxy herbicides and chlorophenols and cancer mortality in the Netherlands. Am J Ind Med 23:289-300.
6. Hooiveld M, Heederik DJJ, Kogevinas M, Boffetta P, Needham LL, Patterson DG, Bueno-de-Mesquita HB. 1998. Second follow-up of a Dutch cohort occupationally exposed to phenoxy herbicides, chlorophenols, and contaminants. Am J Epidemiol 147:891-899.
7. International Agency for Research on Cancer (IARC). 1997. Polychlorinated dibenzo-para-dioxins and polychlorinated dibenzofurans. IARC Monogr Eval Carcinog Risk Hum 69:33-45.
8. Kaddurah-Daouk R, Krishnan KRR. 2008. Metabolomics: A global biochemical approach to the study of central nervous system diseases. Neuropsychopharmacol J 34:173-186.
9. Kogevinas M, Becher H, Benn T, Bertazzi PA, Boffetta P, Bueno-de-Mesqurta HB, Coggon D, Colin D, Flesch-Janys D, Fingerhut M, Green L, Kauppinen T, Littorin M, Lynge E, Mathews JD, Neuberger M, Pearce N, Saracci R. 1997. Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins. An expanded and updated international cohort study. Am J Epidemiol 145:1061-1075.
10. Lin S, Yang Z, Shen Y, Cai Z. 2011. LC/MS-based non-targeted metabolomics for the investigation of general toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in C57BL/6J and DBA/2J mice. Int J Mass Spectrom 301:29-36.
11. Marshall NB, Kerkvliet NI. 2010. Dioxin and immune regulation. Ann N Y Acad Sci 1183:25-37.
12. Mevik BH, Wehrens R. 2007. The pls package: Principal component and partial least squares regression in R. J Stat Softw 18:1-24.
13. Michalek JE, Pirkle JL, Needham LL, Patterson DG Jr, Caudill SP, Tripathi RC, Mocarelli P. 2002. Pharmacokinetics of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in Seveso adults and veterans of operation Ranch Hand. J Expo Anal Environ Epidemiol 12:44-53.
14. Patterson DJ, Isaacs S, Alexander L, Turner W, Hampton L, Bernert J, Needham L. 1991. Determination of specific polychlorinated dibenzo-p-dioxins and dibenzofurans in blood and adipose tissue by isotope dilution-high-resolution mass spectrometry. IARC Sci Publ 108:299-342.
15. Ruiz-Aracama A, Peijnenburg A, Kleinjans J, Jennen D, van Delft J, Hellfrisch C, Lommen A. 2011. An untargeted multi-technique metabolomics approach to studying intracellular metabolites of HepG2 cells exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. BMC Genom 12:251.
16. Saberi Hosnijeh F, Boers D, Portengen L, Bueno-de-Mesquita HB, Heederik D, Vermeulen R. 2011. Long-term effects on humoral immunity among workers exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Occup Environ Med 68:419-424.
17. Saberi Hosnijeh F, Lenters V, Boers D, Portengen L, Baeten E, Bueno-de-Mesquita HB, Heederik DJ, Bloem AC, Vermeulen R. 2012. Changes in lymphocyte subsets in workers exposed to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD). Occup Environ Med 69:781-786.
18. Scheipl F, Fahrmeir L, Kneib T. 2012. Spike-and-slab priors for function selection in structured additive regression models. JASA 107:1518-1532.
19. Storey JD. 2003. The positive false discovery rate: A Bayesian interpretation and the q-value. Ann Stat 31:2013-2035.
20. Veselkov KA, Vingara LK, Masson P, Robinette SL, Want E, Li JV, Barton RH, Boursier-Neyret C, Walther B, Ebbels TM. 2011. Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery. Anal Chem 83:5864-5872.