Tanshinone IIA inhibits human gastric carcinoma AGS cell growth by decreasing BiP, TCTP, Mcl-1 and Bcl-xL and increasing Bax and CHOP protein expression

International Journal of Molecular Medicine

Volumn 34, Issue 6, 2014, Pages 1661-1668

  Su, Chin Cheng ^a,b  

^a CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Endoplasmic reticulum stress; Gastric carcinoma AGS cells; Myeloid cell leukemia 1 protein; Tanshinone IIA; Translationally controlled tumor protein

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; BETA ACTIN; BINDING IMMUNOGLOBULIN PROTEIN; BINDING PROTEIN; CALNEXIN; CASPASE 12; CASPASE 3; CASPASE 9; ENZYME; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INOSITOL REQUIRING ENZYME 1ALPHA; PROTEIN BAX; PROTEIN BCL XL; PROTEIN KINASE; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN MCL 1; TANSHINONE IIA; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; ANTINEOPLASTIC AGENT; BAX PROTEIN, HUMAN; BCL2L1 PROTEIN, HUMAN; CASPASE; DDIT3 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; MCL1 PROTEIN, HUMAN; MOLECULAR CHAPERONE GRP78; PROTEIN BCL X; TANSHINONE; TUMOR MARKER; TUMOR PROTEIN, TRANSLATIONALLY-CONTROLLED 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL GROWTH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; GASTRIC CANCER CELL LINE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; STOMACH CARCINOMA; UPREGULATION; CELL PROLIFERATION; CELL SURVIVAL; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; METABOLISM; PATHOLOGY; STOMACH TUMOR; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BLOTTING, WESTERN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HEAT-SHOCK PROTEINS; HUMANS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; STOMACH NEOPLASMS; TIME FACTORS; TRANSCRIPTION FACTOR CHOP; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84908072596     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2014.1949     Document Type: Article

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