Tanshinone IIA inhibits the growth of Pancreatic cancer BxPC-3 cells by decreasing Protein expression of TCTP, MCL-1 and Bcl-xL

Molecular Medicine Reports

Volumn 7, Issue 3, 2013, Pages 1045-1049

  Huang, Cheng Yen ^a,b   Chiu, Tsung Lang ^c   Kuo, Shou Jen ^a   Chien, Su Yu ^d   Chen, Dar Ren ^a,b   Su, Chin Cheng ^a,b,e  

^a Tumor Research Center of Integrative Medicine   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^d Department of Pharmacy ^*  (China)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

BxPC 3 cells; MCL 1; Tanshinone IIA; TCTP

Indexed keywords

CASPASE 3; PROTEIN BAX; PROTEIN BCL XL; PROTEIN MCL 1; TANSHINONE IIA; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INHIBITION; CELL CYCLE G1 PHASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PANCREAS CANCER; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; CASPASE 3; CELL LINE, TUMOR; DITERPENES, ABIETANE; DOWN-REGULATION; HUMANS; MYELOID CELL LEUKEMIA SEQUENCE 1 PROTEIN; PANCREATIC NEOPLASMS; SALVIA MILTIORRHIZA; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84873110500     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1290     Document Type: Article

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